PAR-24-305-Full-Announcement.html

This document is a Notice of Funding Opportunity (NOFO) for the Centers for Precision Disease Modeling (U54) Cooperative Agreement. The funding opportunity aims to support collaborative research projects that link personalized medicine efforts in human subjects with advances in animal genomics and genetic manipulation technologies, including the creation of interspecies somatic hybrids. The goal is to enhance the predictive value of preclinical studies through the use of precision animal models. Each Center will develop a process to nominate human genomic variants for high-throughput testing in an animal model pipeline, conduct functional and phenotyping analyses, and create and distribute precision animal model resources and related services. The funding is provided by the Department of Health and Human Services, National Institutes of Health, under the Research Infrastructure Programs (CFDA 93.351). The NOFO is open to a wide range of applicant types, including higher education institutions, public housing authorities, state and local governments, for-profit organizations, and non-profit entities.