PA-27-036-Full-Announcement.html

Department of Health and Human Services

Part 1. Overview Information

Participating Organization(s)

National Institutes of Health (NIH)

Components of Participating Organizations

Office of The Director, National Institutes of Health (OD)

National Eye Institute (NEI)

National Heart, Lung, and Blood Institute (NHLBI)

National Human Genome Research Institute (NHGRI)

National Institute on Aging (NIA)

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

National Institute of Allergy and Infectious Diseases (NIAID)

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

National Institute on Deafness and Other Communication Disorders (NIDCD)

National Institute of Dental and Craniofacial Research (NIDCR)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

National Institute on Drug Abuse (NIDA)

National Institute of Environmental Health Sciences (NIEHS)

National Institute of General Medical Sciences (NIGMS)

National Institute of Mental Health (NIMH)

National Institute of Neurological Disorders and Stroke (NINDS)

National Institute of Nursing Research (NINR)

National Library of Medicine (NLM)

National Cancer Institute (NCI)

Tribal Health Research Office (THRO)

All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.

Office of Research on Women's Health (ORWH)

INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE Project)

Office of Data Science Strategy (ODSS)

Funding Opportunity Title

NIH Research Education Program - Research Experiences (Parent R25 - Clinical Trial Not Allowed)

Activity Code

R25 Education Projects

Announcement Type

New

Related Notices

Check for any recent Notices of NIH Policy Changes that may impact application requirements.

Funding Opportunity Number (FON)

PA-27-036

Companion Funding Opportunity

PA-27-034

, R25 Education Projects

PA-27-035

, R25 Education Projects

Number of Applications

See Section III. 3. Additional Information on Eligibility.

Assistance Listing Number(s)

93.310, 93.859, 93.273, 93.279, 93.361, 93.313, 93.T21, 93.233, 93.837, 93.838, 93.839, 93.840, 93.242, 93.866, 93.172, 93.113, 93.THR, 93.121, 93.853, 93.867, 93.173, 93.847, 93.855, 93.879, 93.398, 93.865

Funding Opportunity Purpose

The National Institutes of Health (NIH) Research Education Program supports research education activities in the mission areas of the NIH. The overarching goal of the Research Education program is to:

To accomplish the stated over-arching goal, this NOFO will support educational activities with a primary focus on:

Research Experiences

Funding Opportunity Announcement Goal(s)

NIH's mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability.

Key Dates

Posted Date

Open Date (Earliest Submission Date)

August 25, 2026

The following table includes NIH standard due dates marked with an asterisk.

September 25, 2026 *

September 25, 2026 *

Not Applicable

July 2027

January 25, 2027 *

January 25, 2027 *

Not Applicable

December 2027

May 25, 2027 *

May 25, 2027 *

Not Applicable

April 2028

September 25, 2027 *

September 25, 2027 *

Not Applicable

July 2028

January 25, 2028 *

January 25, 2028 *

Not Applicable

December 2028

May 25, 2028 *

May 25, 2028 *

Not Applicable

April 2029

September 25, 2028 *

September 25, 2028 *

Not Applicable

July 2029

January 25, 2029 *

January 25, 2029 *

Not Applicable

December 2029

May 25, 2029 *

May 25, 2029 *

Not Applicable

April 2030

All applications are due by 5:00 PM local time of applicant organization.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Expiration Date

May 26, 2029

Due Dates for E.O. 12372

Not Applicable

Required Application Instructions

It is critical that applicants follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide, except where instructed to do otherwise (in this NOFO or in a Notice from NIH Guide for Grants and Contracts).

Conformance to all requirements (both in the How to Apply - Application Guide and the NOFO) is required and strictly enforced. Applicants must read and follow all application instructions in the How to Apply - Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the How to Apply - Application Guide, follow the program-specific instructions.

Applications that do not comply with these instructions may be delayed or not accepted for review.

Table of Contents

Part 1. Overview Information Key Dates Part 2. Full Text of Announcement Section I. Funding Opportunity Description Section II. Award Information Other Award Budget Information Section III. Eligibility Information Section IV. Application and Submission Information Section V. Application Review Information Section VI. Award Administration Information Section VII. Agency Contacts Section VIII. Other Information

Part 2. Full Text of Announcement

Section I. Funding Opportunity Description

The NIH Research Education Program (R25) supports research educational activities that complement other formal training programs in the mission areas of the NIH Institutes and Centers.

To help meet these objectives, this Notice of Funding Opportunity (NOFO) will support educational activities with a primary focus on Research Experiences.

Research Education Program Structure Proposed programs should provide mentored research experiences as part of a comprehensive program based on educational practices designed to stimulate the interest, skills and knowledge base of participants. In addition to providing mentored research experiences, programs are expected to include complementary activities appropriate to the educational stage of program participants that support the participants' scientific development, such as scientific writing and presentation skills, and instruction to enhance rigor and reproducibility in research.

Programs should have clear goals and objectives appropriate for the educational level and needs of the audience to be reached, including the content to be conveyed, and the intended outcome(s). For example, outcomes may include the following:

Programs proposed through this R25 can vary in structure and duration. For example, programs can be short-term (e.g., 8–12-week summer research experiences for students or teachers), a full academic or calendar year (e.g., postbaccalaureate research experiences), or spread over multiple years (e.g., part-time mentored research experiences for clinical residents). Programs should be designed consistent with the stated goals and objectives, and the educational stage of the participants to be reached. The proposed program is expected to align with the mission of the NIH Institute, Center, and Office (ICO) to which the application is submitted. ICOs will not support projects, regardless of the results of peer review, if they do not align with current programmatic priorities. Therefore, potential applicants are encouraged to consult scientific/research staff at the intended ICO listed in Section VII before preparing an application. A description of ICO priorities can be found on the NIH Institutes, Centers, and Offices website.

NIH encourages applications from a wide variety of eligible organizations, including those in Institutional Development Award (IDeA)-eligible states, Historically Black Colleges and Universities (HBCUs), and Tribal Colleges and Universities (TCUs). Recipients are encouraged to recruit participants who have the potential to significantly benefit from the program, including those who have not had substantial previous research experience. Consistent with existing NIH practices and applicable law, NIH does not use race, ethnicity, or sex of PI/PD applicants, participants, or program faculty in the application review process or funding decisions. Applicants and award recipients are encouraged to consult with their General Counsel to ensure all applicable laws and regulations are followed in program design and implementation.

Other Considerations Programs focused on research experiences may incorporate secondary elements such as mentoring activities, courses, curriculum and methods development, and outreach; however, those with a primary focus on one of these elements should be submitted to companion R25 NOFO PA-27-035 or PA-27-034, or to other non-parent R25 NOFOs that emphasize mentoring activities, outreach, and/or curriculum and methods development.

Research education programs may complement ongoing research training and education occurring at the applicant organization, but the proposed educational experiences should be distinct from those training and education programs currently receiving Federal support. Research education programs may augment institutional research training programs (e.g., T32, T90) but cannot be used to replace or circumvent Ruth L. Kirschstein National Research Service Award (NRSA) programs.

Additional Information Because of the differences in individual Institute, Center, and Office (ICO) program differences in ICO research education funding considerations, prospective applicants should consult the NIH Institutes, Centers, and Offices website to make sure that their application is appropriate for the requirements of one of the participating NIH ICOs.

See Section VIII. Other Information for award authorities and regulations.

Section II. Award Information

Funding Instrument

Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.

Application Types Allowed

New

Renewal

Resubmission

Revision

The OER Glossary and the How to Apply - Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.

Clinical Trial?

Not Allowed: Only accepting applications that do not propose clinical trial(s). Note: Applications may propose activities involving human subjects that are not deemed clinical trials.

Note: Appointed participants are permitted to obtain research experience in a clinical trial led by a mentor or co-mentor.

Need help determining whether you are doing a clinical trial?

Funds Available and Anticipated Number of Awards

The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Award Budget

Application budgets are not limited, but must reflect the actual needs of the proposed project (See NOT-OD-26-019). Typically, budgets are expected to be no more than $500,000 direct costs.

Applicants should consult staff contacts at participating NIH ICs or the Research Education Funding Considerations and Contacts website for specific budgetary information.

Award Project Period

The scope of the proposed project should determine the project period. The maximum project period is 5 years.

Other Award Budget Information

Personnel Costs

Individuals designing, directing, and implementing the research education program may request salary and fringe benefits appropriate for the person months devoted to the program. Salaries requested may not exceed the levels commensurate with the institution's policy for similar positions and may not exceed the congressionally mandated cap. (If mentoring interactions and other activities with participants are considered a regular part of an individual's academic duties, then any costs associated with the mentoring and other interactions with participants are not allowable costs from grant funds).

Personnel costs (administrative and clerical costs, as well as salaries of the PD/PI, other investigators/faculty, or program coordinators) associated with directing, coordinating, administering, and implementing the program must be well-justified and reasonable. Applicants should consult staff contacts at participating Research Education Funding Considerations and Contacts for specific budgetary information.

Participant Costs

Participants may be compensated for participation in activities specifically required by the proposed research education program, if sufficiently justified. Participant costs must be itemized in the proposed budget.

Allowable participant costs depend on the educational level/career status of the individuals to be selected to participate in the program.

Registration Fees or Tuition - Participants may receive funds to defray registration fees, tuition (including partial tuition), or other education-related expenses if required for the educational experiences offered by the program and if adequately justified.

Travel - Reasonable expenses per participant may be requested to support participant travel to the research site or to a domestic scientific conference. Expenses for foreign travel must be exceptionally well justified.

Housing - When applicable support may be requested to defray the cost of short-term housing at the program site (for example, for undergraduate summer research experiences). Contributions to, or coverage of housing by the institution should be addressed in the Institutional Environment and Commitment section of the application.

Individuals supported by NIH training and career development mechanisms (K, T, or F awards) may receive, and indeed are encouraged to receive, educational experiences supported by an R25 program, as participants, but may not receive salary or stipend supplementation from a research education program.

Because the R25 program is not intended as a substitute for an NRSA institutional training program (e.g.,T32), costs to support full-time participants (supported for 40 hours/week for a continuous, 12-month period) are generally not allowable, unless participants are ineligible for NRSA programs.

Other Program-Related Expenses

Consultant costs, equipment, supplies, travel for key persons, and other program-related expenses may be included in the proposed budget. These expenses must be justified as specifically required by the proposed program and must not duplicate items generally available at the applicant organization.

Indirect Costs

Indirect Costs (also known as Facilities & Administrative [F&A] Costs) are reimbursed at 8% of modified total direct costs (exclusive of tuition and fees, expenditures for equipment and consortium costs in excess of $25,000), rather than on the basis of a negotiated rate agreement.

NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.

Section III. Eligibility Information

1. Eligible Applicants

Eligible Organizations

Nonprofits Other Than Institutions of Higher Education

For-Profit Organizations

Local Governments

Federal Governments U.S. Territory or Possession

Eligible Agencies of the Federal Government

Other

Independent School Districts

Public Housing Authorities/Indian Housing Authorities

Native American Tribal Organizations (other than Federally recognized tribal governments)

Faith-based or Community-based Organizations

Regional Organizations

The sponsoring organization must assure support for the proposed program. Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program.

Institutions with existing Ruth L. Kirschstein National Research Service Award (NRSA) institutional training grants (e.g., T32) or other Federally funded training programs may apply for a research education grant provided that the proposed educational experiences are distinct from those training programs receiving federal support. In many cases, it is anticipated that the proposed research education program will complement ongoing research training occurring at the applicant organization.

Foreign Organizations/International Collaborations

Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Required Registrations

Applicant Organizations Applicant organizations must complete and maintain the following registrations as described in the How to Apply - Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. Failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications for additional information.

System for Award Management (SAM) – Applicants must complete and maintain an active registration, which requires renewal at least annually. The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. Foreign organizations must obtain a NATO Commercial and Government Entity (NCAGE) Code (in lieu of a CAGE code) in order to register in SAM. Unique Entity Identifier (UEI)- A UEI is issued as part of the SAM.gov registration process. The same UEI must be used for all registrations, as well as on the grant application.

Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

All PD(s)/PI(s) must be registered with ORCID. The personal profile associated with the PD(s)/PI(s) eRA Commons account must be linked to a valid ORCID ID. For more information on linking an ORCID ID to an eRA Commons personal profile see the ORCID topic in our eRA Commons online help.

Eligible Individuals (Program Director/Principal Investigator)

Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with their organization to develop an application for support.

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the How to Apply - Application Guide.

The PD/PI should have the required experience and expertise required to provide both administrative and scientific leadership to the development and implementation of the proposed program. The PD/PI will be expected to monitor and assess the program and submit all documents and reports as required.

Multiple PDs/PIs are encouraged, particularly when each brings unique skill sets and experiences that will enhance the research education program. At least one of the PDs/PIs must have a record of using rigorous biomedical research in a field applicable to the program to provide scientific leadership to the development and implementation of the program. Additional PDs/PIs with relevant expertise may be included to strengthen the PD/PI team.

2. Cost Sharing This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement Section 1.2 Definition of Terms.

3. Additional Information on Eligibility Number of Applications

Applicant organizations may submit more than one application, provided that each application is scientifically distinct.

NIH will not accept duplicate or highly overlapping applications under review at the same time per NIH Grants Policy Statement Section 2.3.7.4 Submission of Resubmission Application. This means that the NIH will not accept:

A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.

A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.

An application that has substantial overlap with another application pending appeal of initial peer review. (see NIH Grants Policy Statement 2.3.9.4 Similar, Essentially Identical, or Identical Applications)

Program Faculty Program faculty should have research expertise and experience relevant to the proposed program. Program faculty should demonstrate strong commitments to mentoring and providing safe and supportive research education environments. Programs are encouraged to recruit prospective faculty from various career stages (for example, early-career as well as established faculty).

Participants Unless strongly justified on the basis of exceptional relevance to NIH, research education programs should be used primarily for the education of U.S. citizens and permanent residents.

Eligible participants include high school students, science teachers, undergraduates, postbaccalaureates, predoctoral graduate and health professional students, postdoctoral scholars and those engaged in clinical residency/specialty training, early career and established investigators.

Applications must describe the intended participants, the career levels for which the proposed program is planned, and describe how the content is appropriate for participants. The PI/PD will select the participants to be supported by the research education program (see Research Education Funding Considerations and Contacts website for ICO priorities). It is the responsibility of the applicant organization to establish the qualifications of the participants, consistent with applicable law, before they are supported by the program.

Section IV. Application and Submission Information

1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants.gov Workspace or an institutional system-to-system solution. Links to apply using ASSIST or Grants.gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission It is critical that applicants follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide, except where instructed in this Notice of Funding Opportunity to do otherwise (in this NOFO, in a policy notice, or other notice from NIH Guide for Grants and Contracts). Conformance to the requirements in the How to Apply - Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions will not be reviewed.

Page Limitations

All page limitations described in the How to Apply - Application Guide and the Table of Page Limits must be followed.

Instructions for Application Submission

The following section supplements the instructions found in the How to Apply - Application Guide and should be used for preparing an application to this NOFO.

SF424(R&R) Cover

Follow all instructions provided in the How to Apply - Application Guide.

SF424(R&R) Project/Performance Site Locations

Follow all instructions provided in the How to Apply - Application Guide.

SF424(R&R) Other Project Information Component

Follow all instructions provided in the How to Apply - Application Guide with the following additional modifications:

Facilities & Other Resources. Describe the educational environment, including the facilities, laboratories, participating departments, computer services, and any other resources to be used in the development and implementation of the proposed program. List all thematically related sources of support for research training and education following the format for Current and Pending (Other) Support. Appropriate institutional commitment should include the provision of adequate staff, facilities, and educational resources that can contribute to the planned research education program.

Other Attachments.

An Advisory Committee is not a required component of a Research Education program. However, if an Advisory Committee is intended, provide a plan for the appointment of an Advisory Committee to monitor progress of the research education program. The composition, roles, responsibilities, and desired expertise of committee members, frequency of committee meetings, and other relevant information should be included. Describe how the Advisory Committee will evaluate the overall effectiveness of the program. New applications should not include the names of proposed Advisory Committee members, and proposed members should not be contacted prior to peer review. Renewal applications with Advisory Committees should include the names of all committee members during the past project period. Please name your file "Advisory_Committee.pdf".

The filename provided for each “Other Attachment” will be the name used for the bookmark in the electronic application in eRA Commons.

SF424(R&R) Senior/Key Person Profile Expanded

Follow all instructions provided in the How to Apply - Application Guide.

R&R Budget

Follow all instructions provided in the How to Apply - Application Guide with the following additional modifications:

Include all personnel other than the PD(s)/PI(s) in the Other Personnel section, including clerical and administrative staff.

Use the section on Participant/Trainee Support Costs to include all allowable categories of funds requested to support participants in the program.

PHS 398 Cover Page Supplement

Follow all instructions provided in the How to Apply - Application Guide.

PHS 398 Research Plan

All instructions in the How to Apply - Application Guide must be followed, with the following additional instructions:

Research Strategy

Research Education Program Plan Proposed Research Education Program. While the proposed research education program may complement ongoing research training and education occurring at the applicant organization, the proposed educational experiences must be distinct from those research training and research education programs currently receiving federal support. When research training programs are on-going in the same department, the applicant organization should clearly distinguish between the activities in the proposed research education program and the research training supported by the training program.

For Renewal Applications only:

Include a detailed Progress Report (note that the Progress Report falls within the Research Education Program Plan and is therefore included in the page limits for the Research Education Program Plan). Describe:

Program Director/Principal Investigator. Describe arrangements for administration of the program. Provide evidence that the Program Director/Principal Investigator has the appropriate expertise and experience necessary to organize, administer, monitor, and evaluate the proposed research education program. For programs proposing multiple PDs/PIs, describe the complementary and integrated expertise of the PDs/PIs, their leadership approach, and governance appropriate for the planned project.

Provide evidence that an appropriate level of effort will be devoted by the program leadership to ensure the program's intended goal is accomplished.

Program Faculty. The application should describe how the participating faculty will promote the success of the participants and the research education program. Faculty should have research expertise and experience relevant to the proposed program and demonstrate a history of, or the potential for, their intended roles.

For Renewal Applications Only: Provide information on the applicants and participants in the last funding period. Describe participant outcomes in the context of the program's goals (for example, the number of participants, research products such as scientific presentation and publications, and subsequent career outcomes/accomplishments). Include a description of any changes to the recruitment or selection of participants since the previous application, and why.

Institutional Environment and Commitment. Describe any additional aspects of the Institutional Environment and Commitment not addressed under "Facilities & Other Resources" or the required "Institutional Commitment Letter of Support," described below. Appropriate institutional commitment should include the provision of adequate staff, facilities, and educational resources that can contribute to the planned research education program. This section should not duplicate information provided elsewhere.

Where appropriate, describe any unique features of the scientific environment, subject populations, or collaborative arrangements that may be leveraged to the advantage of the proposed research experiences program. If multiple sites are participating, describe how this will enhance the quality of the research experiences provided, as well as how activities will be coordinated and effective communication maintained among the multiple sites.

Plan for Instruction in Methods to Enhance Reproducibility. Applicants must provide a Plan for Instruction in Methods for Enhancing Reproducibility. The plan should be appropriate and reasonable for the nature and duration of the proposed research education program, considering the specific activities of the proposed research education program and the level of participant experience. See also NIH Guidance: Rigor and Reproducibility in Grant Applications.

Plan for Instruction in the Responsible Conduct of Research. Applicants must provide a plan in the Responsible Conduct of Research (RCR), considering the specific characteristics of the proposed research education program and the level of participant experience. See also: NOT-OD-10-019 and NOT-OD-22-055.

Evaluation Plan. Applications must include a plan for evaluating the activities supported by the award. The application must specify baseline metrics (e.g., numbers, educational levels, etc.), as well as measures to gauge the short or long-term success of the research education award in achieving its objectives. Wherever appropriate, applicants are encouraged to obtain feedback from participants to help identify weaknesses and to provide suggestions for improvements.

Dissemination Plan. A specific plan must be provided to disseminate nationally any findings resulting from or materials developed under the auspices of the research education program, e.g., sharing course curricula and related materials via web postings, presentations at scientific meetings, and workshops.

Letters of Support A letter of institutional commitment must be attached as part of Letters of Support (see "Institutional Environment and Commitment" section above.)

Resource Sharing Plan Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the How to Apply - Application Guide, with the following modification:

Generally, Resource Sharing Plans are not applicable to this Program. When relevant, applications are expected to include a software dissemination plan if support for development, maintenance, or enhancement of software is requested in the application. There is no prescribed single license for software produced.

Other Plan(s):

All instructions in the How to Apply - Application Guide must be followed, with the following additional instructions:

A Data Management and Sharing Plan is not applicable for this NOFO.

Appendix

Only limited Appendix materials are allowed. Follow the instructions for the Appendix as described in the How to Apply - Application Guide.

PHS Human Subjects and Clinical Trials Information When involving human subjects research, clinical research, and/or NIH-defined clinical trials (and when applicable, clinical trials research experience) follow all instructions for the PHS Human Subjects and Clinical Trials Information form in the How to Apply - Application Guide, with the following additional instructions:

If you answered "Yes" to the question "Are Human Subjects Involved?" on the R&R Other Project Information form, you must include at least one human subjects study record using the Study Record: PHS Human Subjects and Clinical Trials Information form or Delayed Onset Study record.

Study Record: PHS Human Subjects and Clinical Trials Information

All instructions in the How to Apply - Application Guide must be followed.

Delayed Onset Study

Note: Delayed onset does NOT apply to a study that can be described but will not start immediately (i.e., delayed start). All instructions in the How to Apply - Application Guide must be followed.

PHS Assignment Request Form

All instructions in the How to Apply - Application Guide must be followed.

3. Unique Entity Identifier and System for Award Management (SAM) See Part 2. Section III.1 for information regarding the requirement for obtaining a unique entity identifier and for completing and maintaining active registrations in System for Award Management (SAM), NATO Commercial and Government Entity (NCAGE) Code (if applicable), eRA Commons, and Grants.gov

4. Submission Dates and Times Part I. contains information about Key Dates and times. Applicants are encouraged to submit applications before the due date to ensure they have time to make any application corrections that might be necessary for successful submission. When a submission date falls on a weekend or Federal holiday, the application deadline is automatically extended to the next business day.

Organizations must submit applications to Grants.gov (the online portal to find and apply for grants across all Federal agencies). Applicants must then complete the submission process by tracking the status of the application in the eRA Commons, NIH's electronic system for grants administration. NIH and Grants.gov systems check the application against many of the application instructions upon submission. Errors must be corrected and a changed/corrected application must be submitted to Grants.gov on or before the application due date and time. If a Changed/Corrected application is submitted after the deadline, the application will be considered late. Applications that miss the due date and time are subjected to the NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications.

Applicants are responsible for viewing their application before the due date in the eRA Commons to ensure accurate and successful submission.

Information on the submission process and a definition of on-time submission are provided in the How to Apply - Application Guide.

5. Intergovernmental Review (E.O. 12372) This initiative is not subject to intergovernmental review.

6. Funding Restrictions All NIH awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement.

Pre-award costs are allowable only as described in the NIH Grants Policy Statement Section 7.9.1 Selected Items of Cost.

7. Other Submission Requirements and Information Applications must be submitted electronically following the instructions described in the How to Apply - Application Guide. Paper applications will not be accepted.

Applicants must complete all required registrations before the application due date. Section III. Eligibility Information contains information about registration.

For assistance with your electronic application or for more information on the electronic submission process, visit How to Apply – Application Guide. If you encounter a system issue beyond your control that threatens your ability to complete the submission process on-time, you must follow the Dealing with System Issues guidance. For assistance with application submission, contact the Application Submission Contacts in Section VII.

Important reminders:

All PD(s)/PI(s) must include their eRA Commons ID in the Credential field of the Senior/Key Person Profile form. Failure to register in the Commons and to include a valid PD/PI Commons ID in the credential field will prevent the successful submission of an electronic application to NIH.

The applicant organization must ensure that the unique entity identifier provided on the application is the same identifier used in the organization's profile in the eRA Commons and for the System for Award Management. Additional information may be found in the How to Apply - Application Guide.

See more tips for avoiding common errors.

Upon receipt, applications will be evaluated for completeness and compliance with application instructions by the Center for Scientific Review, NIH. Applications that are incomplete or non-compliant will not be reviewed.

Mandatory Disclosure

Recipients or subrecipients must submit any information related to violations of federal criminal law involving fraud, bribery, or gratuity violations potentially affecting the federal award. See Mandatory Disclosures, 2 CFR 200.113 and NIH Grants Policy Statement Section 4.1.35.

Send written disclosures to the NIH Chief Grants Management Officer listed on the Notice of Award for the IC that funded the award and to the HHS Office of Inspector Grant Self Disclosure Program at grantdisclosures@oig.hhs.gov.

Post Submission Materials

Applicants are required to follow the instructions for post-submission materials, as described in the policy.

Section V. Application Review Information

1. Criteria Only the review criteria described below will be considered in the review process. Applications submitted to the NIH in support of the NIH mission are evaluated for scientific and technical merit through the NIH peer review system.

For this particular NOFO, note the following:

The goal of this research education program is to support activities that provide research experiences to participants as part of a comprehensive program based on sound educational practices designed to stimulate the interest, skills and knowledge base of participants. Programs should have clear goals and objectives as well as describe appropriate structured activities to achieve those goals.

NIH recognizes that rigorous, well-designed research education programs that further the goal of this NOFO can take place in various organizational environments and with program faculty who have varying levels of NIH research project grant support. Reviewers will evaluate proposed programs considering stated goals and objectives, organizational context, available resources, and the capacity of those resources to meet the stated goals and objectives.

Overall Impact

Reviewers will provide an overall impact score to reflect their assessment of the likelihood for the project to strongly advance research education by fulfilling the goal of this research education program, in consideration of the following review criteria and additional review criteria, as applicable for the project proposed.

Scored Review Criteria

Reviewers will consider each of the review criteria below in the determination of scientific merit and give a separate score for each. An application does not need to be strong in all categories to be judged likely to have major scientific impact.

Significance

Does the proposed program address a key audience and an important aspect or important need in research education? Is there convincing evidence in the application that the proposed program will significantly advance the stated goal of the program?

Investigator(s)

Is the PD/PI capable of providing both administrative and scientific leadership to the development and implementation of the proposed program? Is there evidence that an appropriate level of effort will be devoted by the program leadership to ensure the program's intended goal is accomplished? If applicable, is there evidence that the participating faculty have experience in mentoring students and teaching science? If applicable, are the faculty good role models for the participants by nature of their scientific accomplishments? If the project is collaborative or multi-PD/PI, do the investigators have complementary and integrated expertise; are their leadership approach, governance, and organizational structure appropriate for the project?

Innovation

Taking into consideration the nature of the proposed research education program, does the applicant make a strong case for this program effectively reaching an audience in need of the program’s offerings? Where appropriate, is the proposed program developing or utilizing innovative approaches and latest best practices to improve the knowledge and/or skills of the intended audience?

Approach

Is there evidence that the program is based on a sound rationale, as well as sound educational concepts and principles? Will the approaches employed achieve the stated goals and objectives, including reaching the audience at the intended educational level? Is the plan for evaluation sound and likely to provide information on the effectiveness of the program? If the proposed program will recruit participants, are the planned recruitment, retention, and follow-up (if applicable) activities adequate to ensure an appropriate participant pool?

Environment

Will the scientific and educational environment of the proposed program contribute to its intended goals? Is there a plan to take advantage of this environment to enhance the educational value of the program? Is there evidence of appropriate institutional commitment? Is there evidence that the faculty have sufficient institutional support to create a sound educational environment for the participants?