PA-27-034-Full-Announcement.html
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- NIH Research Education Program - Courses, Curriculum & Methods (Parent R25 - Clinical Trial Not Allowed)
- Opportunity number
- PA-27-034
About this file
This is a Notice of Funding Opportunity (NOFO) for the NIH Research Education Program (R25) supporting educational activities in courses, curriculum development, and methods development. The funding opportunity (PA-27-034) is administered by the National Institutes of Health across 19 participating institutes and centers, with potential co-funding from the Office of Research on Women's Health, INCLUDE Project, and Office of Data Science Strategy. The program supports research education activities that complement workforce training in biomedical, behavioral, and clinical research, with an emphasis on innovative, evidence-based instruction for undergraduate and postgraduate participants. Application deadlines are quarterly (September 25, January 25, May 25) through May 2029, with review cycles occurring in March, July, November, and subsequent months. Award budgets are not limited but typically do not exceed $500,000 in direct costs, with maximum project periods of five years. Eligible applicants include higher education institutions, nonprofits, for-profit organizations, tribal governments, state and local governments, and other entity types; foreign organizations are not eligible. The program does not allow clinical trials.
The NOFO requires applications to address specific educational components including proposed research education program descriptions, program director/principal investigator qualifications, program faculty credentials, participant selection strategies (for courses), institutional environment and commitment, plans for instruction in reproducibility and responsible conduct of research, evaluation plans, and dissemination plans. Applications must be submitted electronically through ASSIST, Grants.gov, or institutional system-to-system solutions and must comply with standard NIH application requirements found in the How to Apply - Application Guide. Personnel costs, participant support (registration, travel, housing), consultant costs, equipment, and supplies are allowable expenses, with indirect costs reimbursed at 8% of modified total direct costs. Applicants must complete registrations in SAM, eRA Commons, and Grants.gov before submission. Scientific review occurs through peer review groups assessing significance, investigator qualifications, innovation, approach, and institutional environment, followed by secondary review by appropriate advisory councils. Funding decisions are based on scientific merit, program priorities, and available funds, with awards subject to NIH Grants Policy Statement requirements and cybersecurity compliance standards.
PA-27-034-Full-Announcement.html
Text of this file
Department of Health and Human Services
Part 1. Overview Information
Participating Organization(s)
National Institutes of Health (NIH)
Components of Participating Organizations
Office of The Director, National Institutes of Health (OD)
National Eye Institute (NEI)
National Heart, Lung, and Blood Institute (NHLBI)
National Human Genome Research Institute (NHGRI)
National Institute on Aging (NIA)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Allergy and Infectious Diseases (NIAID)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute on Drug Abuse (NIDA)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Institute of Nursing Research (NINR)
National Library of Medicine (NLM)
National Cancer Institute (NCI)
Tribal Health Research Office (THRO)
All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
Office of Research on Women's Health (ORWH)
INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE Project)
Office of Data Science Strategy (ODSS)
Funding Opportunity Title
NIH Research Education Program - Courses, Curriculum & Methods (Parent R25 - Clinical Trial Not Allowed)
Activity Code
R25 Education Projects
Announcement Type
New
Related Notices
Check for any recent Notices of NIH Policy Changes that may impact application requirements.
Funding Opportunity Number (FON)
PA-27-034
Companion Funding Opportunity
PA-27-035
, R25 Education Projects
PA-27-036
, R25 Education Projects
Number of Applications
See Section III. 3. Additional Information on Eligibility.
Assistance Listing Number(s)
93.310, 93.847, 93.233, 93.T21, 93.837, 93.838, 93.839, 93.840, 93.867, 93.279, 93.173, 93.859, 93.242, 93.398, 93.273, 93.361, 93.313, 93.172, 93.853, 93.113, 93.121, 93.855, 93.866, 93.879, 93.865
Funding Opportunity Purpose
The National Institutes of Health (NIH) Research Education Program supports research education activities in the mission areas of the NIH. The overarching goal of the Research Education program is to:
| Support educational activities that complement and/or enhance training of a workforce to meet the nation's biomedical, behavioral and clinical research needs; |
| Help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences; and |
| Foster a better understanding of biomedical, behavioral and clinical research and its implications. |
To accomplish the stated over-arching goal, this NOFO will support educational activities with a primary focus on:
Courses for Skills Development
Curriculum or Methods Development
Funding Opportunity Announcement Goal(s)
NIH's mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability.
Key Dates
Posted Date
Open Date (Earliest Submission Date)
August 25, 2026
The following table includes NIH standard due dates marked with an asterisk.
| Application Due Dates |
| Review and Award Cycles |
| New |
| Renewal / Resubmission / Revision (as allowed) |
| AIDS - New/Renewal/Resubmission/Revision, as allowed |
| Scientific Merit Review |
| Advisory Council Review |
| Earliest Start Date |
September 25, 2026 *
September 25, 2026 *
Not Applicable
| March 2027 | |
| May 2027 |
July 2027
January 25, 2027 *
January 25, 2027 *
Not Applicable
| July 2027 | |
| October 2027 |
December 2027
May 25, 2027 *
May 25, 2027 *
Not Applicable
| November 2027 | |
| January 2028 |
April 2028
September 25, 2027 *
September 25, 2027 *
Not Applicable
| March 2028 | |
| May 2028 |
July 2028
January 25, 2028 *
January 25, 2028 *
Not Applicable
| July 2028 | |
| October 2028 |
December 2028
May 25, 2028 *
May 25, 2028 *
Not Applicable
| November 2028 | |
| January 2029 |
April 2029
September 25, 2028 *
September 25, 2028 *
Not Applicable
| March 2029 | |
| May 2029 |
July 2029
January 25, 2029 *
January 25, 2029 *
Not Applicable
| July 2029 | |
| October 2029 |
December 2029
May 25, 2029 *
May 25, 2029 *
Not Applicable
| November 2029 | |
| January 2030 |
April 2030
All applications are due by 5:00 PM local time of applicant organization.
Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.
Expiration Date
May 26, 2029
Due Dates for E.O. 12372
Not Applicable
Required Application Instructions
It is critical that applicants follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide, except where instructed to do otherwise (in this NOFO or in a Notice from NIH Guide for Grants and Contracts).
Conformance to all requirements (both in the How to Apply - Application Guide and the NOFO) is required and strictly enforced. Applicants must read and follow all application instructions in the How to Apply - Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the How to Apply - Application Guide, follow the program-specific instructions.
Applications that do not comply with these instructions may be delayed or not accepted for review.
| There are several options available to submit your application through Grants.gov to NIH and Department of Health and Human Services partners. You must use one of these submission options to access the application forms for this opportunity. | |
| Use the NIH ASSIST system to prepare, submit and track your application online. | |
| Use an institutional system-to-system (S2S) solution to prepare and submit your application to Grants.gov and eRA Commons to track your application. Check with your institutional officials regarding availability. | |
| Use Grants.gov Workspace to prepare and submit your application and eRA Commons to track your application. |
Table of Contents
Part 1. Overview Information Key Dates Part 2. Full Text of Announcement Section I. Funding Opportunity Description Section II. Award Information Other Award Budget Information Section III. Eligibility Information Section IV. Application and Submission Information Section V. Application Review Information Section VI. Award Administration Information Section VII. Agency Contacts Section VIII. Other Information
Part 2. Full Text of Announcement
Section I. Funding Opportunity Description
The NIH Research Education Program (R25) supports research educational activities that complement other formal training programs in the mission areas of the NIH Institutes and Centers.
| Consistent with this purpose, the R25 program is designed to advance several key educational and workforce development objectives: | |
| Support educational activities that complement and/or enhance training of a workforce to meet the nation's biomedical, behavioral, and clinical research needs; | |
| Help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral, and clinical sciences; and | |
| Foster a better understanding of biomedical, behavioral, and clinical research and its implications. |
To help meet these objectives, this Notice of Funding Opportunity (NOFO) will support educational activities with a primary focus on one or both of the following:
| Courses for Skills Development: The proposed course for skills development should provide innovative, state-of-the-art, evidence-based research education that is derived from biomedical, behavioral, social, and/or clinical research methods or findings. The format of the course may involve a traditional in-person approach, online activities, or a hybrid of both approaches based on the needs of the program (for example, advanced courses in a specific discipline or research area, clinical procedures for research, or specialized research techniques). |
| Curriculum or Methods Development: Proposed curriculum or methods development activities should have high potential to improve biomedical, behavioral, or clinical research education, or involve the development of novel instructional approaches or computer-based tools for research education. While the proposed activities can provide a foundation for new courses at the grantee institution, it is expected that the curriculum or methods developed can be readily adaptable by the research education community. |
Research Education Program Structure Applicants should propose projects focused on skills development and provide clear, practical content, with an expectation that participants will leave the program with enhanced research capabilities. Programs that include both didactic and hands-on research experiences, foster partnerships across disciplines and institutions, and employ innovative approaches are encouraged. The proposed program should be appropriate for offering to or being used by participant audiences that include biomedical, behavioral, and clinical researchers (e.g., health care providers; medical, dental, nursing, and other health professional students; graduate students; and/or members of the lay community involved in the dissemination of health information). Proposed programs are intended for participants at the undergraduate level or later career stages.
The following activities are not within the scope of this NOFO:
| Training that is available to the proposed program participants through existing institutional courses. |
| Seminars, workshops, presentations, demonstrations, and related activities that take place at a research conference, scientific symposium, or any other organized, formal meeting. This includes activities that were previously funded by, or are appropriate for support by, the NIH Research Conference Grant (R13 or U13) mechanism. |
| Informational courses that lack concrete practical experience related to the conduct of research, including continuing medical education courses for physicians or other health professionals. |
| Activities that primarily focus on the development or maintenance of mentoring networks or programs. |
Programs submitted under this research education mechanism may vary in structure and duration. For example, the duration of the short courses can vary from one week or less to a maximum of 12 weeks, whereas curriculum or methods development projects may require up to two years for development, testing, and preparation for dissemination before being offered to the intended participant audience. Programs should be designed consistent with the stated goals and objectives, and the educational stage of the audience to be reached. The proposed program is expected to align with the mission of the NIH Institute, Center, or Office (ICO) to which the application is submitted. ICOs will not support projects, regardless of the results of peer review, if they do not align with current programmatic priorities. Therefore, potential applicants are encouraged to consult scientific/research staff at the intended IC listed in Section VII before preparing an application. A description of ICO priorities can be found on the NIH Institutes, Centers, and Offices website.
NIH encourages applications from a wide variety of eligible organizations, including those in Institutional Development Award (IDeA)-eligible states, Historically Black Colleges and Universities (HBCUs), and Tribal Colleges and Universities (TCUs). Grantees are encouraged to recruit participants who have the potential to significantly benefit from the program, including those who have not had substantial previous research experience. Consistent with existing NIH practices and applicable law, NIH does not use the race, ethnicity, or sex of participant candidates, participants, or program faculty in the application review process or funding decisions. Applicants and award recipients are encouraged to consult with their General Counsel to ensure all applicable laws and regulations are followed in program design and implementation.
Other Considerations Programs focused on courses, curriculum, and methods may incorporate secondary elements such as research experiences, mentoring activities, and outreach; however, those with a primary focus on one of these elements should be submitted to companion R25 NOFOs PA-27-036 or PA-27-035, or to other non-parent NOFOs that emphasize research experiences, outreach, and/or mentoring activities.
Research education programs may complement ongoing research training and education occurring at the applicant organization, but the proposed educational experiences should be distinct from those training and education programs currently receiving Federal support. Research education programs may augment institutional research training programs (e.g., T32, T90) but cannot be used to replace or circumvent Ruth L. Kirschstein National Research Service Award (NRSA) programs.
Additional Information Because of the differences in individual ICO program requirements for this announcement, prospective applicants should consult the NIH Institutes, Centers, and Offices website to make sure that their application is appropriate for the requirements of one of the participating NIH ICOs. Prior consultation with participating NIH staff is strongly encouraged.
See Section VIII. Other Information for award authorities and regulations.
Section II. Award Information
Funding Instrument
Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.
Application Types Allowed
New
Renewal
Resubmission
Revision
The OER Glossary and the How to Apply - Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Clinical Trial?
Not Allowed: Only accepting applications that do not propose clinical trial(s). Note: Applications may propose activities involving human subjects that are not deemed clinical trials.
Note: Appointed participants are permitted to obtain research experience in a clinical trial led by a mentor or co-mentor.
Need help determining whether you are doing a clinical trial?
Funds Available and Anticipated Number of Awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Award Budget
Application budgets are not limited, but must reflect the actual needs of the proposed project (See NOT-OD-26-019). Typically, budgets are expected to be no more than $500,000 direct costs.
Applicants should consult with the NIH Institutes, Centers, and Offices website or staff contacts at participating NIH institutes and centers for IC-specific budgetary information.
Award Project Period
The scope of the proposed project should determine the project period. The maximum project period is 5 years.
Other Award Budget Information
Personnel Costs
Individuals designing, directing, and implementing the research education program may request salary and fringe benefits appropriate for the person months devoted to the program. Salaries requested may not exceed the levels commensurate with the institution's policy for similar positions and may not exceed the congressionally mandated cap. (If mentoring interactions and other activities with participants are considered a regular part of an individual's academic duties, then any costs associated with the mentoring and other interactions with participants are not allowable costs from grant funds).
Applicants should consult the participating NIH Institutes, Centers, and Offices website or staff contacts for specific budgetary information.
Participant Costs
For programs with participants:
Participants may be compensated for participation in activities specifically required by the proposed research education program, if sufficiently justified. Participant costs must be itemized in the proposed budget.
Allowable participant costs depend on the educational level/career status of the individuals to be selected to participate in the program.
Registration Fees or Tuition - Participants may receive funds to defray registration fees, tuition (including partial tuition), or other education-related expenses if required for the educational experiences offered by the program and if adequately justified.
Travel - Reasonable expenses per participant may be requested to support participant travel to the research site or to a domestic scientific conference. Expenses for foreign travel must be exceptionally well justified.
Housing - When applicable support may be requested to defray the cost of short-term housing at the program site. Contributions to, or coverage of housing by the institution should be addressed in the Institutional Environment and Commitment section of the application.
Individuals supported by NIH training and career development mechanisms (K, T, or F awards) may receive, and indeed are encouraged to receive, educational experiences supported by an R25 program, as participants, but may not receive salary or stipend supplementation from a research education program.
Because the R25 program is not intended as a substitute for an NRSA institutional training program (e.g.,T32), costs to support full-time participants (supported for 40 hours/week for a continuous, 12-month period) are generally not allowable.
Other Program-Related Expenses
Consultant costs, equipment, supplies, travel for key persons, and other program-related expenses may be included in the proposed budget. These expenses must be justified as specifically required by the proposed program and must not duplicate items generally available at the applicant organization.
Indirect Costs
Indirect Costs (also known as Facilities & Administrative [F&A] Costs) are reimbursed at 8% of modified total direct costs (exclusive of tuition and fees, expenditures for equipment and consortium costs in excess of $25,000), rather than on the basis of a negotiated rate agreement.
NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Section III. Eligibility Information
1. Eligible Applicants
Eligible Organizations
| Higher Education Institutions - Includes all types | |
| Public/State Controlled Institutions of Higher Education | |
| Private Institutions of Higher Education |
Nonprofits Other Than Institutions of Higher Education
| Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education) |
| Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education) |
For-Profit Organizations
| Small Businesses |
| For-Profit Organizations (Other than Small Businesses) |
Local Governments
| State Governments |
| County Governments |
| City or Township Governments |
| Special District Governments |
| Indian/Native American Tribal Governments (Federally Recognized) |
| Indian/Native American Tribal |
| Governments (Other than Federally Recognized) |
Federal Governments U.S. Territory or Possession
Eligible Agencies of the Federal Government
Other
Independent School Districts
Public Housing Authorities/Indian Housing Authorities
Native American Tribal Organizations (other than Federally recognized tribal governments)
Faith-based or Community-based Organizations
Regional Organizations
The sponsoring organization must assure support for the proposed program. Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program.
Institutions with existing Ruth L. Kirschstein National Research Service Award (NRSA) institutional training grants (e.g., T32) or other Federally funded training programs may apply for a research education grant provided that the proposed educational experiences are distinct from those training programs receiving federal support. In many cases, it is anticipated that the proposed research education program will complement ongoing research training occurring at the applicant organization.
Foreign Organizations/International Collaborations
Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Required Registrations
Applicant Organizations Applicant organizations must complete and maintain the following registrations as described in the How to Apply - Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. Failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications for additional information.
System for Award Management (SAM) – Applicants must complete and maintain an active registration, which requires renewal at least annually. The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. Foreign organizations must obtain a NATO Commercial and Government Entity (NCAGE) Code (in lieu of a CAGE code) in order to register in SAM. Unique Entity Identifier (UEI)- A UEI is issued as part of the SAM.gov registration process. The same UEI must be used for all registrations, as well as on the grant application.
| eRA Commons - Once the unique organization identifier is established, organizations can register with eRA Commons in tandem with completing their Grants.gov registration; all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application. |
| Grants.gov – Applicants must have an active SAM registration in order to complete the Grants.gov registration. |
Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.
All PD(s)/PI(s) must be registered with ORCID. The personal profile associated with the PD(s)/PI(s) eRA Commons account must be linked to a valid ORCID ID. For more information on linking an ORCID ID to an eRA Commons personal profile see the ORCID topic in our eRA Commons online help.
Eligible Individuals (Program Director/Principal Investigator)
Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with their organization to develop an application for support.
For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the How to Apply - Application Guide.
The PD/PI should have the required experience and expertise required to provide both administrative and scientific leadership to the development and implementation of the proposed program. The PD/PI will be expected to monitor and assess the program and submit all documents and reports as required.
Multiple PDs/PIs are encouraged, particularly when each brings unique skill sets and experiences that will enhance the research education program. At least one of the PDs/PIs must have a record of using rigorous biomedical research in a field applicable to the program to provide scientific leadership to the development and implementation of the program. Additional PDs/PIs with relevant expertise may be included to strengthen the PD/PI team. The PDs/PIs will be expected to monitor and assess the program and submit all documents and reports as required.
2. Cost Sharing This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement Section 1.2 Definition of Terms.
3. Additional Information on Eligibility Number of Applications
Applicant organizations may submit more than one application, provided that each application is scientifically distinct.
NIH will not accept duplicate or highly overlapping applications under review at the same time per NIH Grants Policy Statement Section 2.3.7.4 Submission of Resubmission Application. This means that the NIH will not accept:
A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.
A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.
An application that has substantial overlap with another application pending appeal of initial peer review. (see NIH Grants Policy Statement 2.3.9.4 Similar, Essentially Identical, or Identical Applications)
Program Faculty Program faculty should have research expertise and experience relevant to the proposed program.
Programs are encouraged to recruit faculty from various career stages, including both early-career and established faculty.
Participants Unless strongly justified on the basis of exceptional relevance to NIH, research education programs should be used primarily for the education of U.S. citizens and permanent residents.
Eligible participants include undergraduates, post-baccalaureates, graduate and health professional students, postdoctoral scholars and those engaged in clinical residency/specialty training, and early-career investigators.
Applications must describe the intended participants, the career levels for which the proposed program is planned, and describe how the content is appropriate for participants. The PI/PD will select the participants to be supported by the research education program (see NIH Institutes, Centers, and Offices website for ICO priorities). It is the responsibility of the applicant organization to establish the qualifications of the participants, consistent with applicable law, before they are supported by the program.
Section IV. Application and Submission Information
1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants.gov Workspace or an institutional system-to-system solution. Links to apply using ASSIST or Grants.gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution.
2. Content and Form of Application Submission It is critical that applicants follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide, except where instructed in this Notice of Funding Opportunity to do otherwise (in this NOFO, in a policy notice, or other notice from NIH Guide for Grants and Contracts). Conformance to the requirements in the How to Apply - Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions will not be reviewed.
Page Limitations
All page limitations described in the How to Apply - Application Guide and the Table of Page Limits must be followed.
Instructions for Application Submission
The following section supplements the instructions found in the How to Apply - Application Guide and should be used for preparing an application to this NOFO.
SF424(R&R) Cover
Follow all instructions provided in the How to Apply - Application Guide.
SF424(R&R) Project/Performance Site Locations
Follow all instructions provided in the How to Apply - Application Guide.
SF424(R&R) Other Project Information Component
Follow all instructions provided in the How to Apply - Application Guide with the following additional modifications:
Facilities & Other Resources. Describe the educational environment, including the facilities, laboratories, participating departments, computer services, and any other resources to be used in the development and implementation of the proposed program. List all thematically related sources of support for research training and education following the format for Current and Pending (Other) Support. Appropriate institutional commitment should include the provision of adequate staff, facilities, and educational resources that can contribute to the planned research education program.
Other Attachments.
An Advisory Committee is not a required component of a Research Education program. However, if an Advisory Committee is intended, provide a plan for the appointment of an Advisory Committee to monitor progress of the research education program. The composition, roles, responsibilities, and desired expertise of committee members, frequency of committee meetings, and other relevant information should be included. Describe how the Advisory Committee will evaluate the overall effectiveness of the program. New applications should not include the names of proposed Advisory Committee members, and proposed members should not be contacted prior to peer review. Renewal applications with Advisory Committees should include the names of all committee members during the past project period. Please name your file "Advisory_Committee.pdf".
The filename provided for each “Other Attachment” will be the name used for the bookmark in the electronic application in eRA Commons.
SF424(R&R) Senior/Key Person Profile Expanded
Follow all instructions provided in the How to Apply - Application Guide.
R&R Budget
Follow all instructions provided in the How to Apply - Application Guide with the following additional modifications:
Include all personnel other than the PD(s)/PI(s) in the Other Personnel section, including clerical and administrative staff.
Use the section on Participant/Trainee Support Costs to include all allowable categories of funds requested to support participants in the program.
PHS 398 Cover Page Supplement
Follow all instructions provided in the How to Apply - Application Guide.
PHS 398 Research Plan
All instructions in the How to Apply - Application Guide must be followed, with the following additional instructions:
Research Strategy
| Research Strategy section must be used to upload the Research Education Program Plan, which must include the following components described below: | |
| Proposed Research Education Program | |
| Program Director/Principal Investigator | |
| Program Faculty | |
| Program Participants (as applicable) | |
| Institutional Environment and Commitment | |
| Plan for Instruction in Methods to Enhance Reproducibility | |
| Plan for Instruction in the Responsible Conduct of Research | |
| Evaluation Plan | |
| Dissemination Plan |
Research Education Program Plan Proposed Research Education Program. While the proposed research education program may complement ongoing research training and education occurring at the applicant organization, the proposed educational experiences must be distinct from those research training and research education programs currently receiving federal support. When research training programs are on-going in the same department, the applicant organization should clearly distinguish between the activities in the proposed research education program and the research training supported by the training program. As a reminder, applicants may choose to address one or more of the activities listed in Section I. Funding Opportunity Description.
| Describe the rationale for the program and how the program will address current needs in methods or curriculum development, or developing skills in biomedical research. Clearly state the objectives of the program and innovative aspects of the program in achieving the aims. In general, applications should: | |
| Provide an overview of the research education program, including length of the program, major programmatic activities, time commitment expected of participants, and the educational concepts and principles on which the program is based. | |
| Clearly state the goals and objectives of the proposed program and how they address the priorities of one of the participating NIH institutes or centers (see NIH Institutes, Centers, and Offices). | |
| Describe innovative aspects and explain the significance of the program. | |
| Provide support for the feasibility of the proposed activities and how they relate to the strengths of the organization and describe the benchmarks to be used to assess the success. | |
| Consider potential problems that may be encountered and describe alternative strategies that could be employed. | |
| Additionally, for programs proposing a curriculum or methods development, describe the educational concepts and principles and basis for the strategy, methodology, and analyses to be employed. Describe key milestones of the proposed activities and plans to evaluate the success of the curriculum or methods development program. Consider potential risks and alternative strategies that could be employed. | |
| Additionally, for programs proposing a course for skills development, clearly outline a plan to recruit and develop meritorious participants. Describe criteria for participant selection, number of participants expected per class, and a description of the course content. Describe plans to enhance coursework with any hands-on activities, mentoring, or networking opportunities as appropriate. Describe how the skills development will contribute to addressing the need for highly trained scientists or health professionals within the mission area of the awarding ICO. |
For Renewal Applications only:
Include a detailed Progress Report (note that the Progress Report falls within the Research Education Program Plan and is therefore included in the page limits for the Research Education Program Plan). Describe:
| Successes and challenges regarding implementing the programmatic elements described in the previous application. State the original specific measurable goals, objectives, and anticipated milestones. Describe program outcomes in the context of those goals, objectives and anticipated milestones, and provide explanations for failing to implement previously proposed programmatic elements. |
| The need for continued support in advancing the programmatic priorities of one of the participating NIH institutes or centers. |
| The progress made in the last funding period. |
| What has been learned through program assessment and how the proposed program content and/or methodologies have been revised since the previous application, and why. |
Program Director/Principal Investigator. Describe arrangements for administration of the program. Provide evidence that the Program Director/Principal Investigator has the appropriate expertise and experience necessary to organize, administer, monitor, and evaluate the research education program. For programs proposing multiple PDs/PIs, describe the complementary and integrated expertise of the PDs/PIs, their leadership approach, and governance appropriate for the planned project.
Program Faculty. Faculty should have research expertise and experience relevant to the proposed program and demonstrate a history of, or the potential for, their intended roles.
| Program Participants (for applications proposing courses). For programs with participants (e.g., those proposing courses), applications must identify the career levels for which the proposed program is planned. | |
| Applications must describe the eligibility criteria and/or specific educational background characteristics that are essential for participation in the proposed program. | |
| Provide details about the pool of expected participants in the program and the sources of the applicant pool. | |
| Describe a recruitment strategy that will reach individuals who may significantly benefit from the program, | |
| Describe how participants will be selected from the eligible applicant pool. |
For Renewal Applications Only: Provide information on the applicants and participants in the last funding period. Describe participant outcomes in the context of the program's goals (for example, the number of participants, research products such as scientific presentation and publications, and subsequent career outcomes/accomplishments). Include a description of any changes to the recruitment or selection of participants since the previous application, and why.
Institutional Environment and Commitment. Describe any additional aspects of the Institutional Environment and Commitment not addressed under "Facilities & Other Resources" or the required "Institutional Commitment Letter of Support," described below. Appropriate institutional commitment should include the provision of adequate staff, facilities, and educational resources that can contribute to the planned research education program. This section should not duplicate information provided elsewhere.
Where appropriate, describe any unique features of the scientific environment, subject populations, or collaborative arrangements that may be leveraged to the advantage of the proposed program. If multiple sites are participating, describe how this will enhance the quality of the experience provided, as well as how activities will be coordinated and effective communication maintained among the multiple sites.
Plan for Instruction in Methods to Enhance Reproducibility (as applicable). For programs with participants, applicant organizations must provide a Plan for Instruction in Methods for Enhancing Reproducibility. The plan should be appropriate and reasonable for the nature and duration of the proposed research education program, considering the specific activities of the proposed research education program and the level of participant experience. See also NIH Guidance: Rigor and Reproducibility in Grant Applications.
Plan for Instruction in the Responsible Conduct of Research. For programs with participants (e.g., those proposing courses), applicants must provide a plan in the Responsible Conduct of Research (RCR), considering the specific characteristics of the proposed research education program and the level of participant experience. See also: NOT-OD-10-019 and NOT-OD-22-055.
Evaluation Plan. Applications must include a plan for evaluating the activities and outcomes supported by the award. The application must specify baseline metrics (e.g., numbers, educational levels, etc.), as well as measures to gauge the short and long-term success of the research education award in achieving its objectives. Wherever appropriate, applicants are encouraged to obtain feedback from participants to help identify weaknesses and to provide suggestions for improvements.
Dissemination Plan. A specific plan must be provided to disseminate nationally any findings resulting from or materials developed under the auspices of the research education program, e.g., sharing course curricula and related materials via web postings, presentations at scientific meetings, and workshops. The dissemination plan should address how the courses, curriculum or methods can be adapted to other organizations.
Letters of Support A letter of institutional commitment must be attached as part of Letters of Support (see section above: "Institutional Environment and Commitment.")
Resource Sharing Plan Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the How to Apply - Application Guide, with the following modification:
Generally, Resource Sharing Plans are not applicable to this Program. When relevant, applications are expected to include a software dissemination plan if support for development, maintenance, or enhancement of software is requested in the application. There is no prescribed single license for software produced.
Other Plan(s):
All instructions in the How to Apply - Application Guide must be followed, with the following additional instructions:
A Data Management and Sharing Plan is not applicable for this NOFO.
Appendix
Only limited Appendix materials are allowed. Follow the instructions for the Appendix as described in the How to Apply - Application Guide.
PHS Human Subjects and Clinical Trials Information When involving human subjects research, clinical research, and/or NIH-defined clinical trials (and when applicable, clinical trials research experience) follow all instructions for the PHS Human Subjects and Clinical Trials Information form in the How to Apply - Application Guide, with the following additional instructions:
If you answered "Yes" to the question "Are Human Subjects Involved?" on the R&R Other Project Information form, you must include at least one human subjects study record using the Study Record: PHS Human Subjects and Clinical Trials Information form or Delayed Onset Study record.
Study Record: PHS Human Subjects and Clinical Trials Information
All instructions in the How to Apply - Application Guide must be followed.
Delayed Onset Study
Note: Delayed onset does NOT apply to a study that can be described but will not start immediately (i.e., delayed start). All instructions in the How to Apply - Application Guide must be followed.
PHS Assignment Request Form
All instructions in the How to Apply - Application Guide must be followed.
3. Unique Entity Identifier and System for Award Management (SAM) See Part 2. Section III.1 for information regarding the requirement for obtaining a unique entity identifier and for completing and maintaining active registrations in System for Award Management (SAM), NATO Commercial and Government Entity (NCAGE) Code (if applicable), eRA Commons, and Grants.gov
4. Submission Dates and Times Part I. contains information about Key Dates and times. Applicants are encouraged to submit applications before the due date to ensure they have time to make any application corrections that might be necessary for successful submission. When a submission date falls on a weekend or Federal holiday, the application deadline is automatically extended to the next business day.
Organizations must submit applications to Grants.gov (the online portal to find and apply for grants across all Federal agencies). Applicants must then complete the submission process by tracking the status of the application in the eRA Commons, NIH's electronic system for grants administration. NIH and Grants.gov systems check the application against many of the application instructions upon submission. Errors must be corrected and a changed/corrected application must be submitted to Grants.gov on or before the application due date and time. If a Changed/Corrected application is submitted after the deadline, the application will be considered late. Applications that miss the due date and time are subjected to the NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications.
Applicants are responsible for viewing their application before the due date in the eRA Commons to ensure accurate and successful submission.
Information on the submission process and a definition of on-time submission are provided in the How to Apply - Application Guide.
5. Intergovernmental Review (E.O. 12372) This initiative is not subject to intergovernmental review.
6. Funding Restrictions All NIH awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement.
Pre-award costs are allowable only as described in the NIH Grants Policy Statement Section 7.9.1 Selected Items of Cost.
7. Other Submission Requirements and Information Applications must be submitted electronically following the instructions described in the How to Apply - Application Guide. Paper applications will not be accepted.
Applicants must complete all required registrations before the application due date. Section III. Eligibility Information contains information about registration.
For assistance with your electronic application or for more information on the electronic submission process, visit How to Apply – Application Guide. If you encounter a system issue beyond your control that threatens your ability to complete the submission process on-time, you must follow the Dealing with System Issues guidance. For assistance with application submission, contact the Application Submission Contacts in Section VII.
Important reminders:
All PD(s)/PI(s) must include their eRA Commons ID in the Credential field of the Senior/Key Person Profile form. Failure to register in the Commons and to include a valid PD/PI Commons ID in the credential field will prevent the successful submission of an electronic application to NIH.
The applicant organization must ensure that the unique entity identifier provided on the application is the same identifier used in the organization's profile in the eRA Commons and for the System for Award Management. Additional information may be found in the How to Apply - Application Guide.
See more tips for avoiding common errors.
Upon receipt, applications will be evaluated for completeness and compliance with application instructions by the Center for Scientific Review, NIH. Applications that are incomplete or non-compliant will not be reviewed.
Mandatory Disclosure
Recipients or subrecipients must submit any information related to violations of federal criminal law involving fraud, bribery, or gratuity violations potentially affecting the federal award. See Mandatory Disclosures, 2 CFR 200.113 and NIH Grants Policy Statement Section 4.1.35.
Send written disclosures to the NIH Chief Grants Management Officer listed on the Notice of Award for the IC that funded the award and to the HHS Office of Inspector Grant Self Disclosure Program at grantdisclosures@oig.hhs.gov.
Post Submission Materials
Applicants are required to follow the instructions for post-submission materials, as described in the policy.
Section V. Application Review Information
1. Criteria Only the review criteria described below will be considered in the review process. Applications submitted to the NIH in support of the NIH mission are evaluated for scientific and technical merit through the NIH peer review system.
For this particular NOFO, note the following:
The goal of this research education program is to support activities that translate the knowledge gained from research into public health applications or educational tools that advance biomedical, behavioral, and clinical research training. Applications should be characterized by a high degree of creativity and scholarship and should provide documentation of a strong need for the proposed course or curriculum or methods to be developed.
Renewal applications should demonstrate a continuing need for the existing course and include a description of how the proposed course content and/or methodologies have been updated since the previous application.
Overall Impact
Reviewers will provide an overall impact score to reflect their assessment of the likelihood for the project to strongly advance research education by fulfilling the goal of this research education program, in consideration of the following review criteria and additional review criteria, as applicable for the project proposed.
Scored Review Criteria
Reviewers will consider each of the review criteria below in the determination of scientific merit and give a separate score for each. An application does not need to be strong in all categories to be judged likely to have major scientific impact.
Significance
Does the proposed program address a key audience and an important aspect or important need in research education? Is there convincing evidence in the application that the proposed program will significantly advance the stated goal of the program?
Investigator(s)
Is the PD/PI capable of providing both administrative and scientific leadership to the development and implementation of the proposed program? Is there evidence that an appropriate level of effort will be devoted by the program leadership to ensure the program's intended goal is accomplished? If applicable, is there evidence that the participating faculty have experience in mentoring students and teaching science? If applicable, are the faculty good role models for the participants by nature of their scientific accomplishments? If the project is collaborative or multi-PD/PI, do the investigators have complementary and integrated expertise; are their leadership approach, governance, and organizational structure appropriate for the project?
Innovation
Taking into consideration the nature of the proposed research education program, does the applicant make a strong case for this program effectively reaching an audience in need of the program’s offerings? Where appropriate, is the proposed program developing or utilizing innovative approaches and latest best practices to improve the knowledge and/or skills of the intended audience?
Approach
Is there evidence that the program is based on a sound rationale, as well as sound educational concepts and principles? Will the approaches employed achieve the stated goals and objectives, including reaching the audience at the intended educational level? Is the plan for evaluation sound and likely to provide information on the effectiveness of the program? If the proposed program will recruit participants, are the planned recruitment, retention, and follow-up (if applicable) activities adequate to ensure an appropriate participant pool?
Environment
Will the scientific and educational environment of the proposed program contribute to its intended goals?
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