PA-27-030-Full-Announcement.html

Department of Health and Human Services

Part 1. Overview Information

Participating Organization(s)

National Institutes of Health (NIH)

Components of Participating Organizations

Office of The Director, National Institutes of Health (OD)

Office of AIDS Research (OAR)

National Eye Institute (NEI)

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

National Institute of Dental and Craniofacial Research (NIDCR)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

National Institute on Drug Abuse (NIDA)

National Institute of Environmental Health Sciences (NIEHS)

National Institute of General Medical Sciences (NIGMS)

National Institute of Neurological Disorders and Stroke (NINDS)

Tribal Health Research Office (THRO)

All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.

Office of Research on Women's Health (ORWH)

INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE Project)

Special Note: Not all NIH Institutes and Centers participate in Parent Announcements. Applicants should carefully note which ICs participate in this announcement and view their respective areas of research interest and priorities on the NIH Institutes, Centers, and Offices website. ICs that do not participate in this announcement will not consider applications for funding. Consultation with NIH staff before submitting an application is strongly encouraged.

Funding Opportunity Title

Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed)

Activity Code

K12 Clinical Scientist Institutional Career Development Program Award

Announcement Type

New

Related Notices

Check for any recent Notices of NIH Policy Changes that may impact application requirements.

Funding Opportunity Number (FON)

PA-27-030

Companion Funding Opportunity

None

Number of Applications

See Section III. 3. Additional Information on Eligibility.

Assistance Listing Number(s)

93.310, 93.867, 93.T21, 93.279, 93.865, 93.121, 93.847, 93.113, 93.859, 93.853, 93.313, 93.THR

Funding Opportunity Purpose

The National Institutes of Health (NIH) will award Institutional Mentored Career Development grants to eligible domestic institutions to support career development programs designed to prepare later stage postdoctoral fellows and junior faculty scholars who have made a commitment to an independent research career for their career advancement and transition to independence. Supported scholars will have "protected time" to engage in intensive, mentored research career development experiences in the fields of biomedical and behavioral research.

This Notice of Funding Opportunity (NOFO) does not allow appointed scholars to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor. NIH strongly supports training towards a career in clinically relevant research. As such, gaining experience in clinical trials under the guidance of a mentor or co-mentor is encouraged.

Funding Opportunity Announcement Goal(s)

NIH's mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability.

Key Dates

Posted Date

June 22, 2026

Open Date (Earliest Submission Date)

September 12, 2026

The following table includes NIH standard due dates marked with an asterisk.

October 12, 2026 *

November 12, 2026 *

Not Applicable

July 2027

February 12, 2027 *

March 12, 2027 *

Not Applicable

December 2027

June 12, 2027 *

July 12, 2027 *

Not Applicable

April 2028

October 12, 2027 *

November 12, 2027 *

Not Applicable

July 2028

February 12, 2028 *

March 12, 2028 *

Not Applicable

December 2028

June 12, 2028 *

July 12, 2028 *

Not Applicable

April 2029

October 12, 2028 *

November 12, 2028 *

Not Applicable

July 2029

February 12, 2029 *

March 12, 2029 *

Not Applicable

December 2029

June 12, 2029 *

July 12, 2029 *

Not Applicable

April 2030

All applications are due by 5:00 PM local time of applicant organization.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Expiration Date

July 13, 2029

Due Dates for E.O. 12372

Not Applicable

Required Application Instructions

It is critical that applicants follow the Training (T) Instructions in the How to Apply - Application Guide, except where instructed to do otherwise (in this NOFO or in a Notice from the NIH Guide for Grants and Contracts). Conformance to all requirements (both in the How to Apply - Application Guide and the NOFO) is required and strictly enforced. Applicants must read and follow all application instructions in the How to Apply - Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the How to Apply - Application Guide, follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.

Table of Contents

Part 1. Overview Information Key Dates Part 2. Full Text of Announcement Section I. Notice of Funding Opportunity Description Section II. Award Information Other Award Budget Information Section III. Eligibility Information Section IV. Application and Submission Information Section V. Application Review Information Section VI. Award Administration Information Section VII. Agency Contacts Section VIII. Other Information

Part 2. Full Text of Announcement

Section I. Notice of Funding Opportunity Description

The overall goal of the NIH Research Career Development programs is to help ensure that a pool of highly trained scientists is available in appropriate disciplines to address the Nation's biomedical, behavioral, and clinical research needs. More information about career programs may be found at the NIH Extramural Research Training and Career Development website.

This NOFO encourages applications from domestic organizations that propose well-designed, rigorous institutional research career development programs in the mission area(s) of the participating ICs.

Supported K12 scholars will be provided with salary and research support for a period of "protected time" to support a tailored career development plan designed to facilitate the scholar's transition to research independence. Proposed institutional career development programs are expected to build on the existing research foundation of appointed scholars to more fully develop the scholar's knowledge and skills to enable them to lead an independent research program that advances knowledge to enhance the Nation's public health.

Program Considerations General Considerations:

Applicant organizations are expected to have the requisite faculty, staff, potential scholars, and facilities on site to conduct the proposed institutional program or sufficient infrastructure to facilitate the recruitment and appointment of scholars nationally if that is the nature of the program proposed. In most cases, it is anticipated that a substantial number of program faculty will have active research projects in which participating scholars may gain relevant experiences consistent with their research interests and goals. The proposed institutional research career development program may complement other, ongoing research training and career development programs at the applicant institution, but the proposed career development experiences are expected to be distinct from those career development programs currently receiving Federal support.

The proposed program is expected to align with the mission of the IC to which the application is submitted. ICs will not support projects, regardless of the results of peer review, if they do not align with current programmatic priorities. Therefore, potential applicants are encouraged to consult scientific/research staff at the intended IC listed in Section VII before preparing an application. A description of ICO priorities can be found on the NIH Institutes, Centers, and Offices website.

Funded programs are expected to be tailored to the organizational context(s) and have clearly defined goals and objectives. Awards should foster safe and supportive research training environments that maximize success for all individuals in the program, demonstrate effective oversight of scholar development, and promote the use of evidence-informed mentoring practices.

Tailored career development plans: This award may be used to support scholars with different levels of prior research training and at different stages of their professional development. As such, programs are expected to develop individualized career development plans for each scholar as congruent with their stated goals and current skill and knowledge levels. Applications should address the process for how these plans are developed and used during the scholar's appointment to ensure successful transition to the next career stage. Programs are also expected to include cohort development activities that allow scholars to learn from each other, work effectively in teams with colleagues, and communicate scientific advances to a wide variety of audiences (discipline specific and the public).

Mentor training/expectations: Effective and well-prepared mentors are integral to the development and advancement of scholars in their research careers. Funded programs are expected to support effective mentorship by ensuring all program faculty complete formal mentor training and continuing education to enhance the ability of mentors to facilitate the transition of scholars to research independence.

Institutional commitment: Funded programs are expected to provide safe and supportive research environments. Awardee institutions are also expected to provide a robust research foundation (institutional programs) for appointed scholars or sufficient infrastructure to facilitate, monitor, and coordinate the progress of mentor-mentee pairs (national programs). For specifics on IC-specific program priorities and solicited program structures, please see IC-specific information on the NIH Institutes, Centers, and Offices website.

NIH encourages applications from a wide variety of eligible organizations, including those in Institutional Development Award (IDeA)-eligible states, Historically Black Colleges and Universities (HBCUs), and Tribal Colleges and Universities (TCUs). Grantees are encouraged to recruit participants who have the potential to significantly benefit from the program, including those who have not had substantial previous research experience but who have the promise to be significant contributors to the biomedical research workforce. Consistent with existing NIH practices and applicable law, (1) funded programs may not use the race, ethnicity, or sex of a participant or faculty mentor candidate as an eligibility or selection criteria, and (2) NIH does not use the race, ethnicity, or sex of participant candidates, participants, or program mentors in the application review process or funding decisions. Applicants and award recipients are encouraged to consult with their General Counsel to ensure all applicable laws and regulations are followed in program design and implementation.

This Notice of Funding Opportunity (NOFO) does not allow appointed scholars to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor. NIH strongly supports training towards a career in clinically relevant research and so gaining experience in clinical trials under the guidance of a mentor or co-mentor is encouraged.

Special Note: The proposed program is expected to align with the mission of the IC to which the application is submitted. ICs will not support projects, regardless of the results of peer review, if they do not align with current programmatic priorities. Therefore, potential applicants are encouraged to consult scientific/research staff at the intended IC listed in Section VII before preparing an application. A description of ICO priorities can be found on the NIH Institutes, Centers, and Offices website.

See Section VIII. Other Information for award authorities and regulations.

Section II. Award Information

Funding Instrument

Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.

Application Types Allowed

New

Renewal

Resubmission

Revision

The OER Glossary and the How to Apply - Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.

Clinical Trial?

Not Allowed: Only accepting applications that do not propose clinical trials.

Note: Appointed Trainees are permitted to obtain research experience in a clinical trial led by a mentor or co-mentor.

Need help determining whether you are doing a clinical trial?

Funds Available and Anticipated Number of Awards

The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Award Budget

Application budgets are not limited, but need to reflect the actual needs of the proposed project.

See Institute, Center, and Office Considerations for Career Development Awards for ICO-specific funding information on the NIH Institutes, Centers, and Offices website.

Award Project Period

The project period duration is up to 5 years.

Other Award Budget Information

Personnel Costs

Individuals designing, directing, and implementing the career development program may request salary and fringe benefits appropriate for the person months devoted to the program. Salaries requested may not exceed the levels commensurate with the institution's policy for similar positions and may not exceed the congressionally mandated cap. If mentoring interactions and other activities with scholars are considered a regular part of an individual's academic duties, then mentoring and other interactions with scholars are non-reimbursable from grant funds.

Salary support for individuals involved in program administration and management must be substantially justified. Salary support for ancillary personnel (e.g. administrative assistance or secretarial support) on CDAs is not allowable.

Scholar Costs

Scholars are those individuals who benefit from the proposed activities and experiences involved in the career development program. Scholar costs must be justified as specifically required for the proposed career development program and based on institutional policies for salaries paid to individuals in similar positions, regardless of the source of funds. These expenses must be itemized in the proposed budget. Applicants are strongly encouraged to consult ICO-specific budget considerationson the NIH Institutes, Centers, and Offices website.

Other Program Related Expenses

Consultant costs, equipment, supplies, travel for key persons, and other program-related expenses (including expenses for mentor training activities) may be included in the proposed budget. These expenses must be justified as specifically required by the proposed program and must not duplicate items generally available at the applicant institution.

Indirect Costs

Indirect Costs (also known as Facilities & Administrative [F&A] Costs) are reimbursed at 8% of modified total direct costs (exclusive of tuition and fees, consortium costs in excess of $25,000, and expenditures for equipment), rather than on the basis of a negotiated rate agreement.

NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.

Section III. Eligibility Information

1. Eligible Applicants

Eligible Organizations

Nonprofits Other Than Institutions of Higher Education

Local Governments

Other

Federal Governments

Eligible Agencies of the Federal Government

U.S. Territory or Possession

The sponsoring institution must assure support for the proposed program. Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program.

Foreign Organizations/International Collaborations

Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.

Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Required Registrations

Applicant Organizations Applicant organizations must complete and maintain the following registrations as described in the How to Apply - Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. The failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications for additional information.

System for Award Management (SAM) – Applicants must complete and maintain an active registration, which requires renewal at least annually. The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. Foreign organizations must obtain a NATO Commercial and Government Entity (NCAGE) Code (in lieu of a CAGE code) in order to register in SAM. Unique Entity Identifier (UEI)- A UEI is issued as part of the SAM.gov registration process. The same UEI must be used for all registrations, as well as on the grant application.

Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

All PD(s)/PI(s) must be registered with ORCID. The personal profile associated with the PD(s)/PI(s) eRA Commons account must be linked to a valid ORCID ID. For more information on linking an ORCID ID to an eRA Commons personal profile see the ORCID topic in our eRA Commons online help.

Eligible Individuals (Program Director/Principal Investigator)

Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research training program as the Training Program Director/Principal Investigator (Training PD/PI) is invited to work with their organization to develop an application for support.

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy, and submission details in the Senior/Key Person Profile (Expanded) Component of the How to Apply - Application Guide.

The PD/PI should be an established investigator in the scientific area in which the application is targeted and capable of providing both administrative and scientific leadership to the development and implementation of the proposed program. The PD/PI will be responsible for the selection and appointment of scholars to the approved career development program, and for the overall direction, management, administration, and evaluation of the program. The PD/PI will be expected to monitor and assess the program and submit all documents and reports as required. The PD/PI has responsibility for the day-to-day administration of the program and is responsible for appointing members of the Advisory Committee (when applicable), using their recommendations to determine the appropriate allotment of funds.

2. Cost Sharing This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement Section 1.2 Definition of Terms.

3. Additional Information on Eligibility

Number of Applications

Applicant organizations may submit more than one application, provided that each application is programmatically distinct.

NIH will not accept duplicate or highly overlapping applications under review at the same time per NIH Grants Policy Statement Section 2.3.7.4 Submission of Resubmission Application. This means that the NIH will not accept:

A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.

A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.

An application that has substantial overlap with another application pending appeal of initial peer review (see NIH Grants Policy Statement 2.3.9.4 Similar, Essentially Identical, or Identical Applications).

Preceptors/Mentors

Program faculty should be active researchers in the biomedical sciences as demonstrated by recent publications and research support in the proposed career development program. Programs are encouraged to recruit prospective preceptors/mentors with relevant experience and expertise to advance the program goals, including faculty at different career stages (for example, early-stage investigators as well as senior faculty). When building a mentoring team, programs should include faculty who are committed to training, mentoring, and providing safe and supportive research training environments. All program faculty should have a mentoring philosophy appropriately tailored to the needs of potential scholars that ensures scholars will receive the tailored mentorship needed to develop skills and advance their career. Mentors are also expected to have, or complete, formal mentoring training and refreshers to enhance their mentoring skills. Program faculty should also have sufficient time to commit to training given their other professional obligations.

Scholars The applicant organization will select the scholars to be supported by the research training program and is responsible for establishing eligibility and selection criteria that are consistent with applicable law.

Scholars must have a research or clinical doctorate degree or their equivalents. Applicants are strongly encouraged to confirm IC-specific degree requirements for appointed scholars with the appropriate participating IC as described on the NIH Institutes, Centers, and Offices website.

Scholars to be supported by the institutional career development program must be at the career level for which the planned program is intended. Scholars are expected to devote a minimum of 9 person-months (75% of full-time professional effort) during the appointment on the K12 award; however, a minimum of 6 person-months is permissible for certain surgical and interventional clinical specialties. Applicants are strongly encouraged to confirm IC-specific minimum effort requirements for appointed scholars with the appropriate participating IC as described on the NIH Institutes, Centers, and Offices website.

Scholars must be citizens or noncitizen nationals of the United States or have been lawfully admitted for permanent residence at the time of appointment. Additional details on citizenship requirements are available in the NIH Grants Policy Statement.

Individuals who are or were PDs/PIs on NIH Small Grant (R03), Exploratory/Developmental Grant (R21), Planning Grant (R34/U34), Dissertation Award (R36), SBIR/STTR Award, Transition Scholar Award (K38) are eligible to be appointed as scholars. However, individuals who have served as PDs/PIs of substantial research project grants (R01), project leaders on sub-projects of multi-component awards, such as program projects (P01) or Center grants (e.g. P50, U54) or the equivalent, are not eligible for appointment under this program. Individuals who have been previously supported by NIH or non-NIH career development awards are not eligible. Scholars may not concurrently hold any other PHS award that duplicates the provisions of this award.

Section IV. Application and Submission Information

1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants.gov Workspace or an institutional system-to-system solution. Links to apply using ASSIST or Grants.gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission It is critical that applicants follow the Training (T) Instructions in the How to Apply - Application Guide except where instructed in this notice of funding opportunity to do otherwise (in this NOFO, in a policy notice, or other notice from NIH Guide for Grants and Contracts). Conformance to the requirements in the How to Apply - Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.

Page Limitations All page limitations described in the How to Apply - Application Guide and the Table of Page Limits must be followed.

Instructions for Application Submission The following section supplements the instructions found in the How to Apply - Application Guide and should be used for preparing an application to this NOFO.

Substitute the term "scholars" for all references to "trainees" in the SF424 (R&R) Application Guide, and substitute the term "career development" for all references to "training" in the SF424 (R&R) Application Guide.

SF424(R&R) Cover All instructions in the SF424 (R&R) Application Guide must be followed.

SF424(R&R) Project/Performance Site Locations All instructions in the How to Apply - Application Guide must be followed.

SF424 (R&R) Other Project Information

Project Summary/Abstract. Provide an abstract of the entire application. Include the goals, objectives, rationale and design of the career development program, as well as key activities in the training plan. Indicate the planned duration of appointments, the projected number of scholars including their educational background, and intended scholar outcomes.

The filename provided for each "Other Attachment" will be the name used for the bookmark in the electronic application in eRA Commons.

SF424(R&R) Senior/Key Person Profile Expanded Follow all instructions provided in the How to Apply - Application Guide.

PHS 398 Cover Page Supplement

PHS 398 Training Subaward Budget Attachment(s)

Research and Related (R&R) Budget Follow all instructions provided in the How to Apply - Application Guide with the following additional modifications:

PHS 398 Research Training Program Plan The PHS 398 Research Training Program Plan Form is comprised of the following sections:

Training Program

Faculty, Trainees, and Training Record

Other Training Program Sections

Appendix- Note that the Appendix should only be used in circumstances covered in the NIH policy on appendix materials or if the NOFO specifically instructs applicants to do so.

Follow all instructions provided in the How to Apply - Application Guide.

Particular attention must be given to the required Training Data Tables. Applicants should summarize, in the body of the application, key data from the tables that highlight the characteristics of the applicant pool, faculty mentors, the educational and career outcomes of past participants, and other factors that contribute to the overall environment of the program.

For this NOFO, only the post-doctoral tables are required.

Program Plan A. Background Institutions with existing programs must explain what distinguishes this program from the others, how their programs will synergize with one another, if applicable, and make it clear that the pool of faculty, potential scholars, and resources are all robust enough to support additional programs.

B. Research Career Development Program Plan

a. Program Administration.

When a program administrator position is planned, a description of the scientific expertise, leadership, and administrative capabilities essential to coordinate a program for developing investigators must be included in the application.

When an administrative coordinator position is planned, a description of the administrative capabilities essential to coordinate a program for developing investigators must be included in the application.

b. Program Faculty Provide a description of how mentors or mentoring teams are established for appointed scholars and how the program will ensure the success of the mentor-mentee relationship. Describe how mentor assessments will be used to improve mentor skills and competencies.

If any mentors will supervise a Scholar gaining research experience in a clinical trial, provide documentation of their expertise, experience, and ability to provide guidance in the organization, management and implementation of the proposed clinical trial, ancillary, or feasibility study and help him/her to meet the study timelines.

c. Proposed Training.

Describe how the proposed career development program will enhance the transition to independence of the appointed scholars and provide program expectations with respect to submission of applications for subsequent support that builds on the scholars' research experience supported by this program.

If a partnership with another academic institution or organization is proposed to support research training or contribute to the professional development of a scholar provide a detailed description of the rationale and the methods for ensuring a strong partnership. Strategies to overcome any logistical challenges should be included.

d. Training Program Evaluation: While funded programs are expected to conduct ongoing program evaluations to monitor the effectiveness of the training activities, Training Program Evaluation is not considered human subjects research.

It is expected that proposed evaluation plans will be based on best practices for program evaluation, to include the program logic model and how that model will facilitate evaluation plans.

e. Scholar Candidates and Retention Plans Describe the proposed support structure and appointment processes, including the stage in the scholars' careers for which they will be supported on the award and the length of appointments.

f. Institutional Environment and Commitment to Training The sponsoring institution must assure support for the proposed program, including assurance that sufficient time will be allowed for the PDs/PIs and other Program Faculty to contribute to the proposed program, and that there will be protected time for scholars (6-9 person months, equivalent to 50%-75% effort) selected for the program. Please note that not all participating ICs permit 6 CM effort for appointed scholars. Applicants are strongly encouraged to review the information on the NIH Institutes, Centers, and Offices website and consult with relevant IC program staff prior to submission.

g. Training outcomes For renewal applications, describe the results of the most recent program evaluation and how those data were utilized to improve the overall program. Explain contextual factors (captured during the evaluation) that might explain differences in training outcomes from expectations.

Other Plan(s):

Follow all instructions provided in the How to Apply - Application Guide with the following additional modifications:

A Data Management and Sharing (DMS) Plan is not applicable to this NOFO.

Appendix:

Limited items are allowed in the Appendix. Follow all instructions for the Appendix as described in the How to Apply - Application Guide; any instructions provided here are in addition to the How to Apply - Application Guide instructions.

PHS Human Subjects and Clinical Trials Information All instructions in the How to Apply - Application Guide must be followed, with the following additional modifications:

Study Record: PHS Human Subjects and Clinical Trials Information DO NOT USE. Attempts to submit a full, detailed study record will result in a validation error.

Delayed Onset Study Note: Delayed onset does NOT apply to a study that can be described but will not start immediately (i.e., delayed start).

If you answered "Yes" to the question "Are Human Subjects Involved?" on the R&R Other Project Information form, you must complete a Delayed Onset Study.

PHS Assignment Request Form

3. Unique Entity Identifier and System for Award Management (SAM) See Part 2. Section III.1 for information regarding the requirement for obtaining a unique entity identifier and for completing and maintaining active registrations in System for Award Management (SAM), NATO Commercial and Government Entity (NCAGE) Code (if applicable), eRA Commons, and Grants.gov

4. Submission Dates and Times Part I. contains information about Key Dates and times. Applicants are encouraged to submit applications before the due date to ensure they have time to make any application corrections that might be necessary for successful submission. When a submission date falls on a weekend or Federal holiday, the application deadline is automatically extended to the next business day.

Organizations must submit applications to Grants.gov (the online portal to find and apply for grants across all Federal agencies). Applicants must then complete the submission process by tracking the status of the application in the eRA Commons, NIH's electronic system for grants administration. NIH and Grants.gov systems check the application against many of the application instructions upon submission. Errors must be corrected and a changed/corrected application must be submitted to Grants.gov on or before the application due date and time. If a Changed/Corrected application is submitted after the deadline, the application will be considered late. Applications that miss the due date and time are subjected to the NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications.

Applicants are responsible for viewing their application before the due date in the eRA Commons to ensure accurate and successful submission.

Information on the submission process and a definition of on-time submission are provided in the How to Apply - Application Guide.

5. Intergovernmental Review (E.O. 12372) This initiative is not subject to intergovernmental review.

6. Funding Restrictions Pre-award costs are allowable only as described in the NIH Grants Policy Statement Section 7.9.1 Selected Items of Cost.

7. Other Submission Requirements and Information Applications must be submitted electronically following the instructions described in the How to Apply - Application Guide. Paper applications will not be accepted.

Applicants must complete all required registrations before the application due date. Section III. Eligibility Information contains information about registration.

For assistance with your electronic application or for more information on the electronic submission process, visit How to Apply – Application Guide. If you encounter a system issue beyond your control that threatens your ability to complete the submission process on-time, you must follow the Dealing with System Issues guidance. For assistance with application submission, contact the Application Submission Contacts in Section VII.

Important reminders:

All PD(s)/PI(s) must include their eRA Commons ID in the Credential field of the Senior/Key Person Profile form. Failure to register in the Commons and to include a valid PD/PI Commons ID in the credential field will prevent the successful submission of an electronic application to NIH.

The applicant organization must ensure that the unique entity identifier provided on the application is the same identifier used in the organization's profile in the eRA Commons and for the System for Award Management. Additional information may be found in the How to Apply - Application Guide.

See more tips for avoiding common errors.

Upon receipt, applications will be evaluated for completeness and compliance with application instructions by the Center for Scientific Review, NIH. Applications that are incomplete or non-compliant will not be reviewed.

Mandatory Disclosure

Recipients or subrecipients must submit any information related to violations of federal criminal law involving fraud, bribery, or gratuity violations potentially affecting the federal award. See Mandatory Disclosures, 2 CFR 200.113 and NIH Grants Policy Statement Section 4.1.35.

Send written disclosures to the NIH Chief Grants Management Officer listed on the Notice of Award for the IC that funded the award and to the HHS Office of Inspector Grant Self Disclosure Program at grantdisclosures@oig.hhs.gov.

Post Submission Materials Applicants are required to follow the instructions for post-submission materials, as described in the policy.

Section V. Application Review Information

1. Criteria

Only the review criteria described below will be considered in the review process.

Applications submitted to the NIH in support of the NIH mission are evaluated for scientific and technical merit through the NIH peer review system.

While any information in the application relevant to the program goals can be included as part of the review process, the race, ethnicity, or sex of program candidates, scholars, or faculty may not, be used as factors in the evaluation of applications.

Overall Impact

Reviewers will provide an overall impact score to reflect their assessment of the likelihood that the proposed career development program will prepare individuals for successful, productive scientific research careers, in consideration of the following review criteria and additional review criteria (as applicable for the project proposed).

Scored Review Criteria

Reviewers will consider each of the review criteria below in the determination of the merit of the training program and give a separate score for each. When applicable, the reviewers will consider relevant questions in the context of proposed short-term training. An application does not need to be strong in all categories to be judged likely to have major career development impact.

Career Development Program and Environment

Program Director(s)/Principal Investigator(s) (PD(s)/PI(s))

Mentors

Scholars

Training Record

Additional Review Criteria

As applicable for the project proposed, reviewers will evaluate the following additional items while determining scientific and technical merit, and in providing an overall impact score, but will not give separate scores for these items.

Protections for Human Subjects

Generally not applicable. Reviewers should bring any concerns to the attention of the Scientific Review Officer.

Inclusion of Human Subjects Policies

Generally not applicable. Reviewers should bring any concerns to the attention of the Scientific Review Officer.

Vertebrate Animals

Generally not applicable. Reviewers should bring any concerns to the attention of the Scientific Review Officer.

Biohazards

Generally not applicable. Reviewers should bring any concerns to the attention of the Scientific Review Officer.

Instruction in the Responsible Conduct of Research

All applications for support under this NOFO must include a plan to fulfill NIH requirements for instruction in the Responsible Conduct of Research (RCR). Taking into account the specific characteristics of the career development program, the level of scholar experience, and the particular circumstances of the scholars, the reviewers will evaluate the adequacy of the proposed RCR career development in relation to the following five required components: 1) Format - Does the plan satisfactorily…