PA-25-306-Full-Announcement.html

This is an NIH Parent Funding Opportunity Announcement (FOA) for the Exploratory/Developmental Research Project Grant (R21) that requires at least one clinical trial. The grant supports early-stage, high-risk research projects that could lead to breakthroughs in biomedical, behavioral, or clinical research through novel techniques, methodologies, or applications.

The opportunity is administered by the Department of Health and Human Services National Institutes of Health and spans multiple research programs including cardiovascular diseases, lung diseases, mental health, alcohol research, drug use and addiction, environmental health, child health and development, deafness and communication disorders, nursing research, blood diseases, human genome research, aging research, and vision research. The grant is open to various applicant types including higher education institutions, nonprofits, small businesses, tribal organizations, and state/local governments. Some participating NIH Institutes and Centers only accept applications proposing mechanistic studies that meet NIH's definition of a clinical trial through this FOA.