PA-25-303-Full-Announcement.html

This is a Notice of Funding Opportunity (NOFO) announcement for the NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required), identified as PA-25-303. The grant supports discrete research projects focused on basic science experimental studies involving human participants that fall within NIH's definition of clinical trials while meeting the criteria for basic research. The funding is specifically for studies that prospectively assign human participants to experimental conditions and assess biomedical or behavioral outcomes to understand fundamental phenomena, without specific applications toward processes or products.

The opportunity is administered by the Department of Health and Human Services National Institutes of Health and encompasses 20 different federal grant programs, including research in areas such as lung diseases, cardiovascular health, mental health, diabetes, alcohol and drug use, environmental health, child development, nursing research, minority health, cancer control, neuroscience, vision research, and aging research. Eligible applicants include higher education institutions, government entities, tribal organizations, nonprofits, for-profit organizations, and small businesses. The funding activities cover education, environment, food and nutrition, health, and income security and social services sectors.