NOTICE OF PROPOSED SOLE SOURCE PURCHASE # 0301-141 RFX # 3150007093.docx
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- Attached to
- 1301-27-R-RFIN-00007
- Solicitation number
- 3150007093
- Issued by
- Mississippi
About this file
This is a Notice of Proposed Sole Source Purchase issued by the Mississippi State Department of Health for the procurement of laboratory equipment. The Mississippi Public Health Laboratory (MPHL) seeks to purchase an Applied Biosystems QuantStudio 5 Dx Real-Time PCR System (Cat. # A47326), an in vitro diagnostic device designed to perform fluorescence-based PCR for detection of nucleic acid sequences in human-derived specimens for use by trained personnel in professional laboratory environments. The system includes comprehensive specifications detailing the instrument's physical dimensions (27 x 50 x 40 cm), temperature range capabilities (4-99.9°C block temperature), performance characteristics including completion of 40-cycle real-time PCR runs in under 30 minutes, and advanced optical features such as the OptiFlex System supporting up to 21 unique wavelength combinations. The procurement is designated as sole source, and objections to this classification must be submitted in writing to Cynthia Brasher, Mississippi State Department of Health Purchasing Department, no later than November 23, 2026 at 10:00 a.m. CST. Any objection must include detailed explanation and supporting documentation demonstrating that the commodity can be provided by another source.
The vendor provides comprehensive support services including a limited warranty of 12-15 months from shipment, orientation training via eLearning or technical scientist, consumables for instrument qualification and performance verification, and optional post-warranty service contracts with next-business-day on-site repairs. The vendor also offers telephone technical support and field applications support. No pricing information is provided in this notice. If the Mississippi State Department of Health determines following review that the commodity can be sourced from another provider, the procurement will be withdrawn and submitted to an advertised competitive bidding process. If the department determines sole source status is justified, it will appeal to the Public Procurement Review Board, bearing the burden of proof that only one source provides this commodity.
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MSSISSIPPI STATE DEPARTMENT OF HEALTH
Notice of Proposed Sole Source Purchase # 301-141 RFx 3150007093
The Mississippi State Department of Health anticipates purchasing the item(s) listed below as a sole source purchase. Anyone objecting to this purchase shall follow the procedures outlined below.
Commodity or commodities to be purchased (make, model, description):
The Mississippi Public Health Laboratory (MPHL) is seeking a Applied Biosystems™ QuantStudio™ 5 Dx Real-Time PCR System (Cat. # A47326) The QuantStudio 5 Dx Real-Time PCR System is an in vitro diagnostic device intended to perform fluorescence-based PCR to provide detection of nucleic acid sequences in human-derived specimens. The QuantStudio 5 Dx Real-Time PCR System is intended for use by trained personnel in a professional environment with FDA-cleared or approved assays.
The QuantStudio 5 Dx system has the following differentiating features and benefits:
System
1. The instrument system includes the instrument, software, user documentation, and either a desktop or laptop computer. The desktop computer may sometimes be referred to as a “tower”.
Instrument
2. The instrument’s dimensions are 27 x 50 x 40 cm (W x D x H), designed to maximize horizontal and vertical bench space.
3. The instrument’s block is accessible from the front of the instrument to maximize bench space and is fully motorized.
4. The instrument’s melt curve or dissociation takes place in steps ranging from 0.015°C ≤ ∆T ≤ 3.66°C
5. The instrument has a maximum block ramp rate of 6.5°C/sec.
6. The instrument block has a temperature range of 4–99.9°C.
7. The instrument heated cover has a temperature range of 50–110ºC.
8. The instrument includes a long-lasting bright white LED (light-emitting diode) source that has a median lifetime of at least 60,000 hours.
9. The instruments use a CMOS imager for data acquisition and collect data for each filter combination in < 2 seconds.
10. The instrument includes a heated lid assembly that heats the top half of the sample plates and provides an effective seal to minimize evaporation of the reaction mixture.
11. The 96-well sample block is made up of 6 separate Peltier elements (known as Applied Biosystems™ VeriFlex™ Blocks). The maximum temperature difference that can be programmed across the block is 25°C. The maximum difference in temperature allowed between adjacent blocks is 5°C.
12. The instrument is designed to support reaction volumes of 10–100 µL on the 0.2 mL 96-well block.
13. The instrument is factory calibrated with FAM™, SYBR™ Green I, VIC™, ABY™, NED™, TAMRA™, JUN™, ROX™, Mustang Purple™, and Cy®5 dyes.
Performance
14. The instrument is designed to complete a 40-cycle real-time PCR run using a fluorogenic 5ʹ nuclease assay and Fast chemistry in under 30 minutes. The instrument can also run in standard ramping mode with standard chemistry.
15. The instrument includes an Applied Biosystems™ OptiFlex™ System that combines 6 excitation (450–670 nm) and 6 emission (500–720 nm) filters, to enable collection of up to 21 unique combinations of wavelengths during a single run for multiplexing.
16. The instrument supports at least two reaction chemistries, the fluorogenic 5ʹ nuclease assay using Applied Biosystems™ TaqMan® probes, and the DNA-binding chemistry of Applied Biosystems™ SYBR™ Green dye.
17. The instrument has real-time quantitative PCR installation specifications to demonstrate the ability to distinguish 5,000 template copies from 10,000 copies at a 99.7% confidence level.
Dx software (IVD)
18. The instrument software allows for locked, IVD use for cleared or approved assays.
19. The instrument software provides secure access and audit records of all user changes.
20. The instrument software includes the ability to assign sample IDs and controls to individual wells.
21. The instrument software helps prevent accidental modifications to run or analysis conditions.
Design
22. The instrument is NRTL TUV SUD certified (tested to safety UL and CAN/CSA standards), EMC certified (tested to IEC 60601-1-2), WEEE compliant, and California Proposition 65 compliant.
Software
23. The software enables users to operate the instrument in either In Vitro Diagnostic (IVD) Mode or Test Development (DEV) Mode. Test Development Mode is for Research Use Only.
24. The instrument desktop software includes security and auditing features, with the ability to maintain centralized settings for multiple units.
Vendor service and support
25. The instrument is provided with a limited warranty for a period of 12–15 months from date of shipment (region dependent). Optional post-warranty service contracts that include next-business-day on-site repairs are available.
26. The instrument is provided with an orientation session by eLearning module or a trained technical scientist.
27. The vendor can supply all the necessary consumables to perform instrument qualification (IQ), operational qualification (OQ), and instrument performance verification (IPV).
28. The vendor can provide computer system validation consulting services with flexible and comprehensive audit-style documentation packages that help users reduce risk and comply with regulations and standards.
29. The vendor offers telephone technical support and field applications, sales, and service support to help resolve chemistry and instrumentation problems.
Any person or entity that objects and proposes that the commodity listed is not sole source and can be provided by another person or entity shall submit a written notice to: Cynthia Brasher, Mississippi State Department of Health Purchasing Department, 570 E. Woodrow Wilson, Room 137A Underwood Building, Jackson, MS 39216 or P. O. Box 1700, Jackson, MS 39215-1700.
Responses may be hand delivered, via regular mail, overnight delivery or by e-mail: cynthia.brasher@msdh.ms.gov The envelope or e-mail should reference the sole source number.
The notice shall contain a detailed explanation of why the commodity is not a sole source procurement. Appropriate documentation shall also be submitted if applicable. The enclosed form (OSS) may be used if you so desire.
If after a review of the submitted notice and documents, Mississippi State Department of Health determines that the commodity in the proposed sole source request can be provided by another person or entity, then Mississippi State Department of Health will withdraw the sole source request publication from the procurement portal website and submit the procurement of the commodity to an advertised competitive bid or selection process.
If Mississippi State Department of Health determines after review that there is only one (1) source for the required commodity, the Mississippi State Department of Health will appeal to the Public Procurement Review Board. Mississippi State Department of Health will have the burden of proving that the commodity is only provided by one (1) source.
Notices/objections, etc. will be accepted at any time prior to: November 23, 2026 at 10:00 a.m. (CST).
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