Notice of Intent to Sole Source_OD.pdf

Synopsis No. 75N98026Q01064

Hospital and Laboratory Support Division Office of Logistics and Operations (OLAO) Office of Acquisition and Logistics Management (OALM)

Title: Two-photon Mesoscale Imaging System with Holographic Stimulation Capability

Presolicitation

SYNOPSIS

General Information

Document Type: Presolicitation Synopsis Number: 75N98026Q01064 Posted Date: August 24, 2026 Original Response Date: September 3, 2026 Current Response Date: September 3, 2026 Set Aside: N/A NAICS Code: 334516

Contracting Office Address

National Institutes of Health (NIH), Office of the Director (OD) Office of Logistics and Operations (OLAO) Office of Acquisition and Logistics Management (OALM) Hospital and Laboratory Support Division 6701 Rockledge Drive Bethesda, MD 20817

Description

INTRODUCTION

THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS

TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL

OR OPEN COMPETITION (INCLUDING BRAND-NAME).

The National Institutes of Health (NIH) intends to negotiate and award a contract without providing for full and open competition (Including brand-name) to:

FEI Company 5350 NE Dawson Creek Drive Hillsboro, Oregon 97124

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under NAICS code 334516 with a Size Standard 1,000.

REGULATORY AUTHORITY

The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2005-99-1, July 16, 2018. This acquisition is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures at an amount not exceeding the simplified acquisition threshold ($350,000).

STATUTORY AUTHORITY

This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1 (b) (1), Soliciting from a single source and is not expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13-Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6- Competition Requirements.

GENERAL INFORMATION

1. Title: Transmission Electron Microscope with Automated Data Collection, Scanning Transmission Mode, and Cryo-Capability

2. Background Information: A 120 kV Transmission Electron Microscope with scanning transmission mode (STEM), that is cryo-capable and is equipped with integrated software for automated 2D data collection, automated tomography tilt series collection, automated single particle data analysis and correlated light-electron microscopy (CLEM) image registration is required by the Joint Electron Microscopy Core (JEM-C). The JEM-C is a shared electron microscopy (EM) facility providing advanced EM services to intramural research programs of three NIH institutes: the National Eye Institute (NEI), the National Institute of Child Health and Human Development (NICHD), and the National Institute of Neurological Disorders and Stroke (NINDS). Each institute is contributing funds for the purchase of this new electron microscope to be a shared instrument, use by intramural researchers from all three institutes.

A modern Transmission Electron Microscope (TEM) with automated data collection capability is essential to fulfill increasing demand for EM data collection and to expand the imaging techniques offered by the JEM-C. Specifically, modern TEM with a high degree of automation of data collection will provide a significantly increased degree of effectiveness in data acquisition which will enable data to be acquired more efficiently and during overnight hours, thereby substantially increasing throughput and productivity of the JEM-C.

Furthermore, such a microscope will provide advanced technical capabilities that enhance services offered by the JEM-C to intramural research programs such as:

1. Automated multiscale 2D TEM image data collection

2. Scanning Transmission EM mode (STEM) with HAADF detector

3. Automated TEM and STEM Tomography data collection for 3D volume imaging

4. Integrated Tomography processing software

5. Integrated Correlative Light-EM software for aligning light and electron correlated images

6. Automated Cryo Box for cryoEM capability

7. Automated single particle data collection and analysis software

8. Offline workstation for 2D, 3D and CLEM image processing and analysis The features listed above will greatly expand the productivity and capability of the JEM-C and are essential the mission of the JEM-C to provide comprehensive state-of-the-art EM resources to the intramural research programs of NEI, NICHD, and NINDS.

CLOSING STATEMENT

This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include a technical proposal, a cost-price proposal, the period of performance, the Unique Entity ID (UEI), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

All responses must be received by September 3, 2026 at 9:00 AM Eastern time and must reference solicitation number 75N98026Q01064. Responses may be submitted electronically to Mr. Michael Falzone, Contracting Officer at Michael.falzone@nih.gov. Fax responses will not be accepted.

"All responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency.”

http://www.sam.gov/