Attach-2B-QASP-PAS-Genotyping-LC-Exhibit.pdf

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NHLBI DNA Resequencing and Genotyping (RS&G) Service: Laboratory Center(s)
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NHLBI-HV-11-21
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QASP Genotyping Attach 2B

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Exhibit - Performance Assessment Scheme (PAS) Genotyping

Key Performance

Requirement Phase Period Performance Standard

Allowable Deviation from

Standard Method of Surveillance Weight

Total Cost Plus Fee

Phase III, Yr. 1

Phase III, Yr. 2

Phase IV, Yr. 1

Phase IV, Yr. 2

95% of awarded amount for period

< 95% 5

95 < 96% 4

96 < 97% 3

97 < 98% 2

98 < 99% 1

Project Officer and Contract

Officer monitoring of financial reports

0-5

Change in Cost ($) per Genotype

Phase III, Yr. 1

Phase III, Yr. 2

Phase IV, Yr. 1

Phase IV, Yr. 2

Compared to Phase II, $/genotype is:

20 percent less in Phase III, Yr. 1

25 percent less in Phase III, Yr. 2

30 percent less in Phase IV, Yr. 1

30 percent less in Phase IV, Yr 2

19 - 20% 10

17 - 18% 8

15 - 16% 6

13 - 14% 4

11 - 12% 2

01 - 10% 0

Project Officer monitoring of

Quarterly Progress Reports and Project Officer & Contract

Officer monitoring of financial reports

0-10

Exceeds Production

Requirements

Phase III, Yr. 1

Phase III, Yr. 2

Phase IV, Yr. 1

Phase IV, Yr. 2

Phase III, Yr. 1: 1,000,000 genotypes

Phase III, Yr. 2: 1,000,000 genotypes

Phase IV, Yr. 1: 2,000,000 genotypes

Phase IV, Yr. 2: 2,000,000 genotypes

>131% 35

126-130% 30

121-125% 25

116-120% 20

111-115% 15

106-110% 10

100-105% 5

<100% 0

Project Officer monitoring

Monthly Status Reports, Quarterly and Annual

Progress Reports, and input from the Oversight Committee

0-35

Exceeds Quality

Requirements

Phase III, Yr. 1

Phase III, Yr. 2

Phase IV, Yr. 1

Phase IV, Yr. 2

Minimum of 95% of selected genotypes produced with design scores >0.8

99-100% 35

97-98% 20

95-96% 10

<95% 0

Project Officer monitoring

Monthly Status Reports, Quarterly and Annual

Progress Reports, and input from the Oversight Committee

0-35

Provides

Community

Assistance and

Outreach

Phase III, Yr. 1

Phase III, Yr. 2

Phase IV, Yr. 1

Phase IV, Yr. 2

1) Complies with confidentiality and security requirements;

2) Present abstracts and/or make presentations at Scientific Meetings, and assist the ACC in staffing the booth at scientific meetings;

3) Assists investigators in selecting variants for genotyping;

4) Data is provided to investigators in a timely manner;

5) Updates in providing information for the RS&G web site are timely.

1) No deviation is allowable;

2) No deviation is allowable;

3) No deviation is allowable;

4) Average processing time is no longer than 3 months from final sample receipt or date of

OPA delivery;

5) Delays in providing information updates for the

RS&G program web site are no greater than 7 days;

6) No deviation is allowable.

Project Officer monitoring

Monthly Status Reports, Quarterly and Annual

Progress Reports, input from investigators using service, and input from the Oversight

Committee; Contracting

Officer monitoring of receipt date of deliverables

0-10

Key Performance

Requirement Phase Period Performance Standard

Allowable Deviation from

Standard Method of Surveillance Weight

6)Advances the state of the art through methodology publications

Effectively meets

NHLBI Needs

Phase III, Yr. 1

Phase III, Yr. 2

Phase IV, Yr. 1

Phase IV, Yr. 2

1) Monthly status reports are clear, concise, and received on due date.

2) Quarterly and Annual progress reports are clear, concise, and are received on due date.

3) Contractor maintains a high level of responsiveness to Project Officer and

Contracting Officer.

4) Financial reports are complete, accurate and submitted on time.

5) Small Business Subcontracting Plan

(SBSP) reports are received on time, and reflect goals being met.

1) Monthly Status Reports require no changes and are received no more than 5 days late.

2) Quarterly and Annual

Progress reports require no changes and are received no more than 5 days late.

3) Responses to requests for information are complete and are received no more than 5 days late.

4) During a 12-month period, financial reports were received no more than 5 days late and require no more than one suspension or disallowance.

5) No deviation allowable.

Project Officer monitoring of

Monthly Status Reports, Quarterly and Annual

Progress Reports, and

Contracting Officer monitoring of contract deliverables

0-5

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