Attach-2A-QASP-PAS-Resequencing-LC-Exhibit.pdf

Exhibit - Performance Assessment Scheme (PAS)

Key Performance Requirement Phase Period Performance Standard

Allowable Deviation from Standard Method of Surveillance Weight

Total Cost Plus Fee Phase III, Yr. 1 Phase III, Yr. 2 Phase IV, Yr. 1 Phase IV, Yr. 2

95% of awarded amount for period

< 95% 5 95 < 96% 4 96 < 97% 3 97 < 98% 2 98 < 99% 1

Project Officer and Contracting Officer monitoring of financial reports

0-5

Change in Cost ($) per Unit (Kb)

Phase III, Yr. 1 Phase III, Yr. 2 Phase IV, Yr. 1 Phase IV, Yr. 2

Compared to Phase II, $/Kb are:

20 percent less in Phase III, Yr. 1 25 percent less in Phase III, Yr. 2 30 percent less in Phase IV, Yr. 1 30 percent less in Phase IV, Yr 2

19 - 20% 10 17 - 18% 8 15 - 16% 6 13 - 14% 4 11 - 12% 2 01 - 10% 0

Project Officer monitoring of Quarterly Progress Reports and Project Officer & Contracting Officer monitoring of financial reports

0-10

Exceeds Production Requirements

Phase III, Yr. 1 Phase III, Yr. 2 Phase IV, Yr. 1 Phase IV, Yr. 2

Phase III, Yr. 1: 75,000 Kb Phase III, Yr. 2: 110,000 Kb Phase IV, Yr. 1: 120,000 Kb Phase IV, Yr. 2: 120,000 Kb

>100% 35 98-99% 30 96-97% 25 94-95% 20 92-93% 15 90-91% 10 88-89% 5 <87% 0

Project Officer monitoring Monthly Status Reports, Quarterly and Annual Progress Reports, and input from the Oversight Committee

0-35

Exceeds Quality Requirements

Phase III, Yr. 1 Phase III, Yr. 2 Phase IV, Yr. 1 Phase IV, Yr. 2

80% of genotypes prodced across scanned regions

87-90% 35 84-86% 20 81-83% 10 <80% 0

Project Officer monitoring Monthly Status Reports, Quarterly, and Annual Progress Reports, and input from the Oversight Committee

0-35

Provides Community Assistance and Outreach

Phase III, Yr. 1 Phase III, Yr. 2 Phase IV, Yr. 1 Phase IV, Yr. 2

1) Complies with confidentiality and security requirements;

2) Present abstracts and/or make presentations at Scientific Meetings, and assist the ACC in staffing the booth at scientific meetings;;

3) Assists investigators in selecting variants for genotyping;

4) Data is provided to investigators in a timely manner;

5) For Coriell samples, SNPs are forwarded to public databases in a timely manner;

1) No deviation is allowable,

2) No deviation is allowable,

3) No deviation is allowable,

4) Phase III, year 1: See footnote 1below.

Phase III, year 2 and Phase IV years 1 and 2: See footnote 2 below.

5) For Coriell samples, SNPs are sent to public databases in accordance with RS&G policies and prcedures.

6) Delays in providing

Project Officer monitoring Monthly Status Reports, Quarterly and Annual Progress Reports, and input from the Oversight Committee

0-10

Exhibit - Performance Assessment Scheme (PAS)

Key Performance Requirement Phase Period Performance Standard

Allowable Deviation from Standard Method of Surveillance Weight

6) Updates in providing information for the RS&G web site are timely;

7) Advances the state of the art through methodology publications information updates for the RS&G program web site are no greater than 7 days

7) No deviation is allowable

Effectively meets NHLBI Needs

Phase III, Yr. 1 Phase III, Yr. 2 Phase IV, Yr. 1 Phase IV, Yr. 2

1) Monthly status reports are clear, concise, and received on due date.

2) Quarterly and Annual progress reports are clear, concise, and are received on due date.

3) Contractor maintains a high level of responsiveness to Project Officer and Contracting Officer.

4) Financial reports are complete, accurate and submitted on time.

5) Small Business Subcontracting Plan (SBSP) reports are received on time, and reflect goals being met.

1) Monthly Status Reports require no changes and are received no more than 5 days late.

2) Quarterly and Annual Progress Reports require no changes and are received no more than 5 days late.

3) Responses to requests for information are complete and are received no more than 5 days late.

4) During a 12-month period, financial reports were received no more than 5 days late and require no more than one suspension or disallowance.

5) No deviation allowed.

Project Officer monitoring of Monthly Status Reports, Quarterly and Technical Progress Reports, and Contracting Officer monitoring of contract deliverables

0-5

Footnotes: 1) Coriell DNA 1 + (total baseline sequence/6.25 Mbp) months; Investigator DNA 2 + (total baseline sequence/6.25 Mbp) months.

2) Coriell DNA 1 + (total baseline sequence/10 Mbp) months; Investigator DNA 2 + (total baseline sequence/10 Mbp) months.