MaterialsSafetyDataSheet-micromount.pdf

Material Safety Data Sheet Histology / Cytology Reagents Micromount® Mounting Medium

Section 1. Product and Preparation Information Product Identifier Micromount Mounting Medium

Product Use Coverslipping and slide preparation

Date Prepared August 2006

Synonym / Chemical Name Xylene mixed isomers, dimethylbenzene, methyltoluene, methacrylic acid methyl ester, MMA

Document #

Manufacturer/ Preparer Surgipath Canada, Inc. Surgipath Medical Industries, Inc.

83 Terracon Place 5205 Route 12 Winnipeg, Manitoba R2J 4B3 Richmond, IL 60071

Emergency Contact Chemtrec USA and Canada 800.424.9300 Chemtrec International 703.527.3887 Canadian Non-Transport Calls 800.665.7425 USA Non-Transport Calls 800.225.8867

Section 2. Preventive Measures Personal Protection NFPA US DOT

Canadian WHMIS B2 D1A, D2A

Personal Protection

Eyes Safety glasses Body Laboratory coat Respiratory NIOSH/MSHA approved respirator when ventilation is inadequate Hands Latex or nitrile gloves

Emergency Overview

Highly flammable liquid and vapor, vapor may cause flash fire. Cannot be made non-poisonous.

May be fatal if swallowed. Contains material that may cause kidney, lung and liver damage. Keep away from heat, sparks and flame. Keep container closed. Use only with adequate ventilation.

Wash thoroughly after handling. Do not get in eyes

Engineering Controls General mechanical ventilation or laboratory fume hood. Ensure that eyewash stations and quick drench showers are proximal to the workstation or tissue processor.

Handling and Storage Dissipate static electricity during transfer by grounding and bonding containers and equipment. If air concentrations may exceed lower explosive limit, use explosion-proof equipment. Keep containers closed and out of reach of children. Do not use near open flames or sparks. Store at room temperature.

Store in flammable liquid safety cabinet when possible.

Small Spill and Leak Absorb with an inert dry material and place in an appropriate waste disposal container.

Large Spill and Leak Keep away from heat and ignition sources. Stop leak if without risk. Absorb with DRY earth, sand or other non-combustible material. Avoid skin and eye contact. Prevent entry into sewers, basements or confined areas: dike if needed. Eliminate all ignition sources. Be careful that airborne concentrations do not exceed published exposure and lower explosive limits.

Waste Disposal Unused Product – Dispose as a regulated hazardous waste. Spent product or spill clean up - Follow all provincial and federal rules.

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Section 3. Hazardous Ingredients Hazardous Ingredient % wt. CAS Number LD50 LC50

Xylene

<60

1330-20-7

4,300 mg/kg oral rat 2,119 mg/kg oral mouse

5,000 ppm/4 hr. inhalation rat

Ethylbenzene

<10

100-41-4

3,500 mg/kg oral rat

NA

Acrylic Resin

<40

80-62-6

7,872 mg/kg oral rat 3,625 mg/kg oral mouse

78,000 mg/m³/4hr inhalation rat 18,500 mg/m³/2hr inhalation mouse

Plasticizer

<10

84-74-2

7499 mg/kg oral rat 3,474 mg/kg oral mouse

4,250 mg/m³ inhalation rat 25 gm/m³/2hr inhalation mouse

Antioxidant

128-37-0

TDG PIN

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Section 4. First Aid Measures

Eye Contact Immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation persists.

Skin Contact Remove contaminated clothing immediately. Wash the affected areas with soap or mild detergent and large amounts of water for at least 15 minutes.

Inhalation Move individual to fresh air immediately. If breathing is difficult, give oxygen. If breathing has stopped, administer artificial respiration.

Get medical attention.

Ingestion Never give anything by mouth to an unconscious person. Give no more than 2 glasses of water. Get medical attention immediately.

Section 5. Physical Data Physical State Liquid

Odor and Appearance Aromatic hydrocarbon clear

Odor Th eshold (ppm) r 11 ppm

Solubility Insoluble in water

Auto-ignition Temp 870° F (465.5° C)

Vapor Pressure 15.26mmHg @ 20C

Vapor Density

4.13 (air-1)

Evaporation Rate N/A

Boiling Point 278° F (136° C)

Flash Point CC 44° F (6° C) pH N/A

Specific Gravity

0.91 Water=1

Coeff. Water/oil Dist.

N/A

Freezing Point -64° F (-53° C)

Flammable Limits

LEL – 1% UEL – 7%

Section 6. Fire and Explosion Flammability Conditions Fl. Pt - Auto Ignition - Flammable Limits Flammable Liquid IB (Canada B2) Excessive heat, sparks and open flames. See Physical Data above Explosivity Not explosive under normal conditions of use. Vapors are heavier than air and may settle in low areas. Vapors may travel long distances to an ignition source and flash back explosively. Flame may be invisible. Not sensitive to impact. Probably will not accumulate static charge due to high electrical conductivity, however proper grounding during transfer is recommended (NFPA 77).

Hazardous Combustion Products Carbon monoxide, carbon dioxide

Means of Extinction Small Fire – Use DRY chemical powder. Large Fire – Use alcohol foam, water spray or fog

Section 7. Reactivity Stability Product is stable under normal conditions of use.

Hazardous Decomposition Products Fumes, smoke, carbon monoxide and aldehydes

Conditions of Reactivity

NA

Hazardous Polymerization No hazardous polymerization.

Incompatibility Isolate from strong oxidizers, permanganates, chromates and peroxides

Section 8. Toxicological Properties Routes of Entry Absorbed through skin, eye, inhalation and ingestion.

Target Organs Liver, kidney, gastrointestinal tract, reproductive and nervous systems.

Effects of Acute Exposure Eye Slightly hazardous in case of eye contact (irritant, corrosive). May cause eye burns Skin Slightly hazardous (irritant). Skin inflammation is characterized by itching, scaling, reddening or occasionally blistering.

Absorption May be absorbed through skin, eye, inhalation and ingestion Inhalation Slightly hazardous in case of inhalation Ingestion May be fatal if swallowed Effects of Chronic Exposure Xylene is toxic to blood, kidneys, the nervous system, liver, gastrointestinal tract, upper respiratory tract skin and eyes. Inhalation may worsen conditions such as emphysema or bronchitis. Repeated skin exposure may cause defatting of the skin.

Carcinogenic Effects Classified A4 (not classified for humans) ACGIH. Classified 3 (not classifiable for human) IARC.

Reproductive Toxicity Detected in maternal milk in humans. Passes through the placental barrier in animal. Embryotoxic and/or foetotoxic in animal Teratogenic and Mutagenic Effects NA

Exposure Limits OSHA PEL TWA ACGIH TLV TWA STEL TWAEV (Ont.) STE V (Ont.) CEV (Ont.)

Xylene 100 ppm 100 ppm, 150 ppm C 150 ppm 100 ppm (Alberta) 150 ppm (Alberta) NA

Ethylbenzene 435 mg/m³ 100 ppm, 125 ppm C 125 ppm 100 ppm 125 ppm NA

Dibutyl phthalate 5 mg/m³ 5 mg/m³, 10 mg/m³ C NA 5 mg/m³ NA NA

2,6-di-tert,2-butyl-P-cresol NA 10 mg/m³, 20 mg/m³ C NA NA NA NA

Methyl methacrylate 410 mg/m³ 100 ppm, 125 ppm C NA 100 ppm 125 ppm NA

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Section 9. Regulatory Information OSHA Hazardous Yes

Cal. Prop. 65 Ethylbenzene listed as carcinogen

Canadian WHMIS B2, D1A, D2A

RCRA Regulated D001, F003

SARA 302/304

Not Listed

SARA 313

Listed

CERCLA 102A

Listed

RQ

100 lbs. mixed isomers

CWA 307

Listed

CWA 311

Not Listed

CAA 112 Release Prevention Listed

CAA 112 Reg. Flam. Substance Not Listed

CAA 112 Reg. Toxic Substance Not Listed

TSCA Inventory All ingredients Listed

EEC Flammability R11 – Highly Flammable

CEPA DSL

All ingredients Listed

Proper US DOT Shipping Name Flammable Liquids, NOS (methyl methacrylate, xylene), 3, UN1993, PG II

TDG Classification

Class 3 Flammable Liquid

IATA Classification

Class 3 Flammable Liquid

Limited Quantity

Yes

The information provided above is based upon unused product. Product characteristics may change after processing, requiring further classification.

This Material Safety Data Sheet has been prepared in accordance with the Canadian Controlled Products Regulations and 29CFR1910.1200. To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein.