amendment2.pdf

RFP Number : N02CO07013-64 Amendment 2

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OFFICE OF ACQUISITIONS

NATIONAL CANCER INSTITUTE

REQUEST FOR PROPOSAL NUMBER: N02CO07013-64

Amendment No.: 2

Date of Issuance: May 18, 2010

The above numbered Request for Proposal (RFP) is amended as set forth below. The hour and date specified for receipt of Offerors remains unchanged, 2:00PM local time (Eastern Prevailing Time) on June 4, 2010.

Offerors MUST acknowledge receipt of the amendment prior to the hour and the date specified in the solicitation or as amended, by separate letter, telegram, or Electronic Mail which includes a reference to the RFP and Amendment number(s). For your convenience, the Proposal Intent Response Form is provided in SECTION J - List of Attachments of this RFP, for this purpose.

FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERORS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER.

This Amendment revises the RFP as stated below:

I. Below is the Government's response to questions received regarding this RFP:

1. SOW page 10: BCR capabilities required to support this Statement of Work, bullet point 5 - Deploy BCR operating and management infrastructure, including governance and oversight interfaces, advisory board(s), informatics, reporting systems, and necessary laboratory certifications, and personnel credentials.

Question: Could you provide clarification on the duties and ideal make-up of the advisory board?

RESPONSE: The advisory board should be composed of individuals who are experts in the field of DNA/molecular diagnostics, pathology, clinical genetics and high throughput production processes. The advisory board should be able to provide a contractor with guidance on work flow in a high throughput molecular diagnostic laboratory and the development of specialized protocols for processing tumors that fall outside of the scope of standard molecular diagnostic procedures. The board should also contain expertise in molecular diagnostic laboratory informatics and standard pathology procedures.

2. SOW page 10: BCR capabilities required to support this Statement of Work, bullet point 6 - States we are to manage interactions with the Center for Biomedical Informatics and Information Technology (CBIIT) and Office of Biorepositories and Biospecimen Research (OBBR)

Question: Who are the BCR's contacts at OBBR and CBIIT and what are the expectations for interactions?

RESPONSE: The Government is unable to release contact names during the solicitation phase of this project. The contact names will made available to the successful offerors upon contract award. The offerors will be expected to provide accurate and timely information (including but not limited to information already provided in the required deliverables mentioned in Article C. ) to both CBIIT and OBBR as requested by the CO or COTR.

3. SOW page 36: 5.1 Informatics, Specific BCR informatics system components requirements include, bullet point 3 - Specific requirement to implement the NCI Global Unique Identifier (GUID).

Question: When will the GUID go into production and what is the expectation to transform "legacy" samples to incorporate the GUID?

RESPONSE: There is a GUID system that is already in place within the Data Coordinating Center. The new system will be available in the next couple of months and will be operational at the time of award. Retrospective assignment of GUIDs to existing objects in the database should be completed by the end of the first quarter of funding (90 days).

RFP Number : N02CO07013-64 Amendment 2

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4. SOW page 42: 6.3 Project Key Personnel, BCR Project manager. This individual shall serve as overall project manager, and shall be credentialed in project management from an accredited project management education organization.

Question: What is the expectation for the time frame obtaining project management credentialing? Does the credentialing need to be in place by the time of award or can it be in progress to be completed within a certain number of months post award?

RESPONSE: The BCR Project Manager will be required to demonstrate progress towards receive this certification.

If the individual can demonstrate proper experience, training and capacity equivalent to a professional certification in Project Management (including a minimum three years/36 months unique non-overlapping professional project management experience during which at least 4,500 hours were spent leading and directing project tasks), the requirement of the certification may be waived or delayed for up to 12 months to provide the Project Manager sufficient time to gain this certification.

5. RFP page 25: - C.2. The Contractor shall submit a roster…of all staff (including subcontractor staff) working under the contract who will develop, have the ability to access, or host and/or maintain a Federal information system(s).

Question: Can you please define a Federal information system? Does accessing a NCI sharepoint site fall under this category?

RESPONSE: A Federal information system is any website, program or other site that is hosted by the federal government. The TCGA Sharepoint site is hosted by the NCI and is considered a Federal information system that is covered under this part of the SOW.

6. RFP page 41: Attachment 10. Do we need to provide detailed budget information for consumables (office supplies, etc.)?

RESPONSE: While the granular detail of the number of pens, reams of paper, etc... is not required, some information about the distribution of your requirements under this line item will be helpful in the review of your budget.

7. Is this a new procurement or are there incumbents? If it is existing, what are the values of these contracts?

RESPONSE: The subject solicitation is a new project/procurement.

ALL OTHER TERMS AND CONDITIONS OF THIS REQUEST FOR PROPOSAL REMAIN UNCHANGED.