N01CN25001-26 Amendment3.pdf

OMB No 0990-0115

1. CONTRACT ID CODE PAGE OF PAGES

AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT N/A 1 3

2. AMENDMENT/MODIFICATION NO. 3. EFFECTIVE DATE 4. REQUISITION/PURCHASE REQ. NO. 5. PROJECT NO. (If applicable)

3 April 12, 2012 N/A

6. ISSUED BY CODE 7. ADMINISTERED BY (If other than Item 6) CODE N/A National Institutes of Health National Cancer Institute Office of Acquisitions Executive Plaza South, Suite 600 6120 Executive Blvd, MSC 7193 Bethesda, Maryland 20892-7193

8. NAME AND ADDRESS OF CONTRACTOR (No. Street, County, State and ZIP: Code) (�) 9A. AMENDMENT OF SOLICITATION NO.

TO ALL POTENTIAL OFFERORS

N01CN25001-26

9B. DATED (SEE ITEM 11)

March 09, 2012

10A. MODIFICATION OF CONTRACT/ORDER NO.

10B. DATED (SEE ITEM 13)

CODE FACILITY CODE

11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS

The above numbered solicitation is amended as set forth in Item 14. The hour and date specified for receipt of Offers is extended, is not extended.

Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the following methods:

(a) By completing Items 8 and 15, and returning one (1) copy of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer submitted;

or (c) By separate letter or telegram which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATA SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by telegram or letter, provided each telegram or letter makes reference to the solicitation and this amendment, and is received prior to the opening hour and data specified.

12. ACCOUNTING AND APPROPRIATION DATA (If required)

13. THIS ITEM APPLIES ONLY TO MODIFICATIONS OF CONTRACTS/ORDERS,

IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14.

(�) A. THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT ORDER NO. IN ITEM 10A.

B. THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as changes in paying office, appropriation date, etc.) SET

FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF FAR 43.103(b).

C. THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:

D. OTHER (Specify type of modification and authority)

E. IMPORTANT: Contractor is not, is required to sign this document and return 1 copies to the issuing office.

14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, including solicitation/contract subject matter where feasible.)

PURPOSE: 1)To provide clarification of GLP Compliant, date of proposal submission and revision of Attachment 9 “Additional Technical Proposal Instructions” and Attachment 1 “Packaging and Delivery of Proposals” on RFP N02CN25001-26 “Preclinical In Vitro and In Vivo Agent Development Assays”

Proposal Due Date: April 23, 2012; 3:00pm (EST) (Unchanged)

Except as provided herein, all terms and conditions of the document referenced in Item 9A or 10A, as heretofore changed, remains unchanged and in full force and effect.

15A. NAME AND TITLE OF SIGNER (Type or print) 16A. NAME AND TITLE OF CONTRACTING OFFICER (Type or print)

Virginia DeSeau Contracting Officer, NCI OA, NIH

15B. CONTRACTOR/OFFEROR 15C. DATE SIGNED 16B. UNITED STATES OF AMERICA 16C. DATE SIGNED

(Signature of person authorized to sign)

BY ______________/s/_______________________________ (Signature of Contracting Officer)

04/12/2012

NSN 7540-01-152-8070 30-105 STANDARD FORM 30 (REV. 10-83)

PREVIOUS EDITION UNUSABLE Computer Generated Prescribed by GSA

FAR (48 CFR) 53.243

Solicitation N01CN25001-26 Amendment #3 – Questions and Responses

Preclinical In Vitro and In Vivo Agent Development Assays

1. Is the proposed work GLP, 21 CFR Part 58 compliant?

No, the Task Orders do not have to be GLP compliant

2. Is the due date for proposal submission extended?

The due date for proposal submission is unchanged: April 23, 2012, 3:00 p.m. EST local time.

Any proposal received after the due date/time is considered late and will be treated in accordance with procedures contained in HHSAR 352.215-70-Late Proposals and Revisions, found in SECTION L, page 46 which states:

SECTION L – INSTRUCTIONS, CONDITIONS, AND NOTICES TO OFFERORS

LATE PROPOSALS AND REVISIONS

j. LATE PROPOSALS AND REVISIONS, HHSAR 352.215-70 (January 2006) Notwithstanding the procedures contained in FAR 52.215-1(c)(3) of the provision of this solicitation entitled Instructions to Offerors-Competitive Acquisition, the Government may consider a proposal received after the date specified for receipt if it appears to offer the best value to the Government and it was received before proposals were distributed for evaluation, or within 5 calendar days after the exact time specified for receipt, whichever is earlier.

Clarification: In accordance with the 5 calendar days cited above, the last day a late proposal could be received by the Government is Friday, April 27, 2012, since the Government is not open on Saturday, April 28, 2012.

3. Attachment 9, Additional Technical Proposal Instructions, page 2, is revised to clarify the requirement for double-sided printing, as follows: (see yellow highlights):

Under “Documents submitted using Adobe.pdf shall be submitted using a pdf searchable format” ‘single-sided’ is changed to ‘double-sided,’ as follows:

Print set up should be double-sided on standard letter size paper (8.5X11”)

4. Attachment 1, PACKAGING AND DELIVERY OF PROPOSALS is revised to delete “ONE ORIGINAL *HARDCOPY AND 12 CDS,” which is replaced as follows:

A. TECHNICAL PROPOSAL ONLY

ONE (1) ORIGINAL UNBOUND*HARDCOPY, NO BINDERS,

THREE (3) UNBOUND DUPLICATE HARDCOPIES, NO BINDERS; and ONE Set of CDs (includes the business proposal and the technical proposal)

TO:

and:

B. BUSINESS PROPOSAL

ONE (1) ORIGINAL UNBOUND*HARDCOPY, NO BINDERS,

THREE (3) UNBOUND DUPLICATE HARDCOPIES, NO BINDERS; and ONE Set of CDs (includes the business proposal and the technical proposal)

TO: