HERMES_BAA_Attachment_C_Proposal_Summary_Slide_Template.pptx

This document is a proposal summary slide template for the Hermes program solicitation (HR001124S0025) issued by the Defense Advanced Research Projects Agency (DARPA). The Hermes program is seeking proposals to develop systemic drug delivery platforms for medical countermeasures (MCMs). Key requirements include a detailed description of the proposed delivery platform, including a screening pipeline, reporter systems for monitoring biodistribution and expression in animal models, methods to monitor immunogenicity/toxicity, and the chosen therapeutic cargo. Successful proposals will describe transformative approaches enabling the development of delivery platforms with systemic biodistribution, exceptional endosomal escape efficiency, and minimal toxicity. The delivery platforms developed under this effort will be transferred to U.S. Government stakeholders for further development.