HERMES_BAA_Attachment_A_Abstract_Summary_Side_Template.pptx

This document is an Abstract Summary Slide Template for the Hermes Broad Agency Announcement (BAA) solicitation number HR001124S0025. The Hermes program is a DARPA effort to develop systemic drug delivery platforms for medical countermeasures. Key details include:

The Hermes program is seeking transformative approaches for delivery platforms with systemic biodistribution, exceptional endosomal escape efficiency, and minimal toxicity. Successful proposals should include a detailed description of the proposed delivery platform, including 1) screening pipeline, 2) reporter systems for monitoring biodistribution and expression in animal models, 3) methods to monitor immunogenicity/toxicity, and 4) the chosen therapeutic cargo and justification. Systemic delivery platforms developed under Hermes will be transferred to U.S. Government stakeholders for further development.