Attachment_4_Sample_Technical_Directives_DRAFT.pdf

TD-XXX

Defense Threat Reduction Agency

And USSTRATCOM Center for Combating WMD

8725 John J. Kingman Rd. Stop 6201 TECHNICAL DIRECTIVE (TD)

Fort Belvoir, VA 22060-6201

1. CONTRACT NUMBER

HDTRA1-16-R-0001

2. CONTRACTOR 3a.TD NUMBER

S-001

3b.REV NUMBER

4. TD TITLE

Next Generation Sequencing Capacity Building for

Detection of High-Risk Pathogens at the Lugar Center, Georgia

5. TOTAL TD ESTIMATE (Not to Exceed):

HOURS: _____1040__________ DOLLARS: $ __350,000.00_______

6. CONTRACING OFFICER REPRESENTATIVE

NAME:___DTRA STEP COR____________

PHONE: _(555) 555-5555__ EMAIL: __NAME@MAIL.MIL____

7. CONTRACTOR POC

NAME:____________________________________________________________________

PHONE: __________________ EMAIL: _______________________________

8. DESCRIPTION OF TD (NOT TO EXCEED 1 PAGE):

The Defense Threat Reduction Agency (DTRA) Cooperative Biological Engagement Program (CBEP) requests the

Contractor provide a Next Generation Sequencing (NGS) subject matter expert (SME) for scientific mentorship and research collaboration for research activities at the Richard G. Lugar Center for Public Health Research in Georgia. The

Contractor should provide mentorship for two Georgian scientists working at the Lugar Center and two graduate students working under supervision of those scientists, in collecting, analyzing and interpreting genomic data resulting from CBEP-sponsored research work. The expert should provide this training in the context of building capacity of the

Lugar Center as an independent and regional leader for NGS work for the purpose of detecting and reporting high-risk pathogens. This mentorship is expected to be provided by a mid-level scientific subject matter expert (SME) in NGS.

To further facilitate capacity building, in addition to hands-on training in NGS, the expert should provide mentorship and guidance to Georgian scientists in preparing and submitting NGS-focused grant proposals to the DTRA

Fundamental Research Broad Agency Announcement (BAA), and other competitive research funding solicitations. It is expected that this mentorship will result in at least one project submitted to the BAA Thrust Area 6, and at least one project submitted to a separate solicitation (to be determined in coordination with the Georgian scientists). The SME is expected to assist the Georgian researchers with all phases of proposal development, to include responding appropriately to requests for revisions when necessary. It is the intention of CBEP that the grant development and proposal submission be led by the Georgian researchers, with the NGS SME providing assistance and mentorship as needed in meeting funding agency requirements and deliverable deadlines. This assistance is essential as the Georgian researchers continue the transition from in-country BTRIC support to independent work.

SME support and mentorship should be provided both in-country and remotely. It is expected the SME will make 4 x 2 week trips to Georgia to provide NGS and proposal development support. Timing of the trips should be based on research data analysis and proposal development needs following discussions with Georgian researchers. Additional support should be provided by the SME via email and teleconferences.

The period of performance for this requirement is eighteen (18) months. It is expected that implementation of this requirement will require approximately 26 weeks of effort consisting of 4 x 2 week trips to Tbilisi, Georgia, with additional time allotted for pre- and post-trip activities and follow-up actions, and an additional 10 weeks of effort for coordination, document reviews, and remote reach-back support. The budget for implementing this requirement should not exceed $350,000.

9a. PROPOSED SOLUTION (NOT TO EXCEED 2 PAGES):

9b. BUDGET (USE SEPARATE DOCUMENT FOR BUDGET BREAKDOWN:

COST CATEGORY TOTAL

LABOR $0

MATERIALS $0

TRAVEL $0

TOTAL $0.00

D R A

FT

9c. TD SOLUTION BASIS OF ESTIMATE – DESCRIPTION (NOT TO EXCEED 2 PAGES):

10. FUNDING AUTHORIZED THIS TD REV:

COST CATEGORY COST POP START POP END

LABOR -$

MATERIALS

TRAVEL

TOTAL -$

11a. FUNDS AUTHORIZED FOR THIS TD REV:

11b. FUNDS AUTHORIZED INCLUSIVE OF ALL

REV:

12a. CURRENT PERIOD OF PERFORMANCE

12b. TD REV PERIOD OF PERFORMANCE

13. CONTRACTOR

Signature:________________________________________________

Date:___________________________

14. REGION

CENTCOM/TURKEY

15. TECHNICAL POINTS OF CONTACT

(i.e., Country Manager/Regional Lead/Science Manager, A&AS)

16. CONTRACTING OFFICER REPRESENTATIVE APPROVAL

Signature:________________________________________________

Date:_____________________

COMMENTS (OPTIONAL):

D R

Instructions: Offeror to complete blocks 2, 7, 9, and 13.

1. Contract Number

2. Contractor – Full Company Name

3. Technical Directive Number

4. Technical Directive Title

5. Total Estimated Technical Directive - Hours and Dollars (Not to Exceed)

6. Contracting Officer Representative – Contact details

7. Contractor Point of Contact – Details

8. Description of the Technical Directive – Government Provided

9. Solution:

a. Proposed Solution: Contractor’s proposed solution (including approach, schedule, and risk analysis) for TD. Not to exceed 2 pages.

b. Budget: Contractor enter proposed quantity(ies) for TD completion by using the embedded Excel workbook.

c. Technical Directive Solution Basis of Estimate – Description: Contractor complete the BOE for proposed solution to TD. Not to exceed 2 pages.

10. Funding Authorized this TD: Identifies information for billing purposes

11. Funds Authorized

a. Funds Authorized for this TD Revision Exclusively

b. Funds Authorized inclusive of all Revisions, Cumulative Total

12. Period of Performance

a. Current

b. TD Rev POP

13. Contractor: Sign & Date

14. Region for Technical Directive

15. Contracting Officer Approval: Sign & Date

16. Contracting Officer Representative Approval: Sign & Date

D R

And USSTRATCOM Center for Combating WMD

8725 John J. Kingman Rd. Stop 6201 TECHNICAL DIRECTIVE (TD)

Fort Belvoir, VA 22060-6201

1. CONTRACT NUMBER

HDTRA1-16-R-0001

2. CONTRACTOR 3a.TD NUMBER

S-002

3b.REV NUMBER

4. TD TITLE

Training Workshops: Biosafety/Biosecurity Practices

Training and Differential Diagnosis Sessions

5. TOTAL TD ESTIMATE (Not to Exceed):

HOURS: _____400__________ DOLLARS: $ __130,000.00_______

6. CONTRACING OFFICER REPRESENTATIVE

NAME:___DTRA STEP COR____________

PHONE: _(555) 555-5555__ EMAIL: __NAME@MAIL.MIL____

7. CONTRACTOR POC

NAME:____________________________________________________________________

PHONE: __________________ EMAIL: _______________________________

8. DESCRIPTION OF TD (NOT TO EXCEED 1 PAGE):

The Defense Threat Reduction Agency (DTRA) Cooperative Biological Engagement Program (CBEP) requests the Contractor provide hands-on laboratory training for Guinea public health professionals for training on (1) biosafety/biosecurity practices when handling suspected infectious samples (including secure collection, handling, storage, and shipment), and (2) differential diagnosis of Viral Hemorrhagic Fevers in the laboratory. The Contractor shall use existing training materials, previously developed for similar CBEP-sponsored training in West Africa. Labor should not exceed three (3) medium level trainers per cohort for no more than two (2) training sessions per cohort; the use of qualified regionally/locally-based trainers is preferable to the maximum extent practical. Each training cohort should consist of a maximum of 6 people and should last a total of 4 days. Training participants and training locations should be identified in conjunction with representatives of the Guinea Ministry of Health and the assistance of the

CBEP Guinea Country Manager. The mix of training participants should consist of clinicians and nurses that are part of the

National Institute of Public Health (INSP), the central reference laboratory in the country. Materials and supplies (such as Personal

Protective Equipment (PPE), diagnostic kits, and laboratory consumables) should not exceed $20,000. The PoP for this activity is 5 months and the efforts should not exceed (NTE) $130,000.

9a. PROPOSED SOLUTION (NOT TO EXCEED 2 PAGES):

9b. BUDGET (USE SEPARATE DOCUMENT FOR BUDGET BREAKDOWN:

COST CATEGORY TOTAL

LABOR $0

MATERIALS $0

TRAVEL $0

TOTAL $0.00

9c. TD SOLUTION BASIS OF ESTIMATE – DESCRIPTION (NOT TO EXCEED 2 PAGES):

10. FUNDING AUTHORIZED THIS TD REV:

COST CATEGORY COST POP START POP END

LABOR -$

MATERIALS

TRAVEL

TOTAL -$

11a. FUNDS AUTHORIZED FOR THIS TD REV:

11b. FUNDS AUTHORIZED INCLUSIVE OF ALL

REV:

12a. CURRENT PERIOD OF PERFORMANCE

12b. TD REV PERIOD OF PERFORMANCE

13. CONTRACTOR

Signature:________________________________________________

Date:___________________________

COMMENTS (OPTIONAL):

D R

14. REGION

CENTCOM/TURKEY

15. TECHNICAL POINTS OF CONTACT

(i.e., Country Manager/Regional Lead/Science Manager, A&AS)

16. CONTRACTING OFFICER REPRESENTATIVE APPROVAL

Signature:________________________________________________

Date:_____________________

D R

2. Contractor – Full Company Name

3. Technical Directive Number

4. Technical Directive Title

5. Total Estimated Technical Directive - Hours and Dollars (Not to Exceed)

6. Contracting Officer Representative – Contact details

7. Contractor Point of Contact – Details

8. Description of the Technical Directive – Government Provided

9. Solution:

a. Proposed Solution: Contractor’s proposed solution (including approach, schedule, and risk analysis) for TD. Not to exceed 2 pages.

b. Budget: Contractor enter proposed quantity(ies) for TD completion by using the embedded Excel workbook.

c. Technical Directive Solution Basis of Estimate – Description: Contractor complete the BOE for proposed solution to TD. Not to exceed 2 pages.

10. Funding Authorized this TD: Identifies information for billing purposes

11. Funds Authorized

a. Funds Authorized for this TD Revision Exclusively

b. Funds Authorized inclusive of all Revisions, Cumulative Total

12. Period of Performance

a. Current

b. TD Rev POP

13. Contractor: Sign & Date

14. Region for Technical Directive

15. Contracting Officer Approval: Sign & Date

16. Contracting Officer Representative Approval: Sign & Date

D R

And USSTRATCOM Center for Combating WMD

8725 John J. Kingman Rd. Stop 6201 TECHNICAL DIRECTIVE (TD)

Fort Belvoir, VA 22060-6201

1. CONTRACT NUMBER

HDTRA1-16-R-0001

2. CONTRACTOR 3a.TD NUMBER

S-003

3b.REV NUMBER

4. TD TITLE

Veterinary Epidemiology Training and Simultaneous

Outbreak Response, Detection and Diagnosis SME Support in Cambodia

5. TOTAL TD ESTIMATE(Not to Exceed):

HOURS: _____2750__________ DOLLARS: $ __850,000.00_______

6. CONTRACING OFFICER REPRESENTATIVE

NAME:___DTRA STEP COR____________

PHONE: _(555) 555-5555__ EMAIL: __NAME@MAIL.MIL____

7. CONTRACTOR POC

NAME:____________________________________________________________________

PHONE: __________________ EMAIL: _______________________________

8. DESCRIPTION OF TD (NOT TO EXCEED 1 PAGE):

The Defense Threat Reduction Agency (DTRA) Cooperative Biological Engagement Program (CBEP) requests that the Contractor implement introductory veterinary epidemiology trainings in Phnom Penh and Kampong Cham for a total of 50 Cambodian personnel in the Ministry of Agriculture that serve as animal health sector staff and are responsible for disease outbreak detection and response. Trainings should include classroom instruction, as well as practical sessions in the form of field work. Courses should include, but not be limited to, topics on biostatistics, risk factors, and disease surveillance. In addition to classroom instruction, a directed research project (approximately 3-6 months in duration) should be incorporated into the trainings in order to maximize the application of instruction. The trainings should reflect current best surveillance practices in the field and reuse existing CBEP materials to the maximum extent possible. Trainers for this task should be up to three (3) mid-level veterinary epidemiologists, or with equivalent expertise. In developing the implementation plan, the Contractor should account for the fact that Cambodia is currently experiencing an outbreak of suspected highly pathogenic avian influenza (HPAI), which may require the attention of

Cambodian government personnel identified to participate in the training.

DTRA CBEP also requests that the Contractor provide six (6) months of SME support and relevant operational training to the

Cambodian Ministry of Agriculture and Cambodian Ministry of Health personnel in response to the suspected HPAI outbreak, which is estimated to affect up to 300 people. Trainings should reflect current best surveillance practices in the field and reuse existing CBEP materials where possible. It is expected that the SME support will be based in Cambodia for the full six months.

Support to the Government of Cambodia during this time should encompass, but not be limited to, diagnostic testing of human and animal samples collected during the outbreak, assistance to Cambodian ministries in the development of case definitions and epidemiological analyses, and related epidemiological training for 15 Cambodian personnel. Trainings should be provided to

Cambodian Ministry of Agriculture and Ministry of Health personnel by up to two (2) high-level Subject Matter Experts (SMEs), identified by the Contractor with extensive experience with veterinary epidemiology and avian influenza outbreak response, This training should be provided to the Cambodian government personnel conducting sample collection and testing associated with the outbreak. Recipients of trainings should be chosen in coordination with the relevant ministries based upon their existing level of responsibility for disease detection, response and reporting.

The Period of Performance for this requirement is 12 months. CBEP estimates that all forms of support, including travel budget for travel, six months of continuous lodging and meals, laboratory materials for diagnostic testing, field supplies, and up to 750 labor hours for introductory veterinary epidemiology training, should not exceed $850,000.

9a. PROPOSED SOLUTION (NOT TO EXCEED 2 PAGES):

9b. BUDGET (USE SEPARATE DOCUMENT FOR BUDGET BREAKDOWN:

COST CATEGORY TOTAL

LABOR $0

MATERIALS $0

TRAVEL $0

TOTAL $0.00

9c. TD SOLUTION BASIS OF ESTIMATE – DESCRIPTION (NOT TO EXCEED 2 PAGES):

D R

10. FUNDING AUTHORIZED THIS TD REV:

COST CATEGORY COST POP START POP END

LABOR -$

MATERIALS

TRAVEL

TOTAL -$

11a. FUNDS AUTHORIZED FOR THIS TD REV:

11b. FUNDS AUTHORIZED INCLUSIVE OF ALL

REV:

12a. CURRENT PERIOD OF PERFORMANCE

12b. TD REV PERIOD OF PERFORMANCE

13. CONTRACTOR

Signature:________________________________________________

Date:___________________________

14. REGION

CENTCOM/TURKEY

15. TECHNICAL POINTS OF CONTACT

(i.e., Country Manager/Regional Lead/Science Manager, A&AS)

16. CONTRACTING OFFICER REPRESENTATIVE APPROVAL

Signature:________________________________________________

Date:_____________________

COMMENTS (OPTIONAL):

D R

2. Contractor – Full Company Name

3. Technical Directive Number

4. Technical Directive Title

5. Total Estimated Technical Directive - Hours and Dollars (Not to Exceed)

6. Contracting Officer Representative – Contact details

7. Contractor Point of Contact – Details

8. Description of the Technical Directive – Government Provided

9. Solution:

a. Proposed Solution: Contractor’s proposed solution (including approach, schedule, and risk analysis) for TD. Not to exceed 2 pages.

b. Budget: Contractor enter proposed quantity(ies) for TD completion by using the embedded Excel workbook.

c. Technical Directive Solution Basis of Estimate – Description: Contractor complete the BOE for proposed solution to TD. Not to exceed 2 pages.

10. Funding Authorized this TD: Identifies information for billing purposes

11. Funds Authorized

a. Funds Authorized for this TD Revision Exclusively

b. Funds Authorized inclusive of all Revisions, Cumulative Total

12. Period of Performance

a. Current

b. TD Rev POP

13. Contractor: Sign & Date

14. Region for Technical Directive

15. Contracting Officer Approval: Sign & Date

16. Contracting Officer Representative Approval: Sign & Date

D R

And USSTRATCOM Center for Combating WMD

8725 John J. Kingman Rd. Stop 6201 TECHNICAL DIRECTIVE (TD)

Fort Belvoir, VA 22060-6201

1. CONTRACT NUMBER

HDTRA1-16-R-0001

2. CONTRACTOR 3a.TD NUMBER

S-004

3b.REV NUMBER

4. TD TITLE

Research Proposal Development Support in Turkey

5. TOTAL TD ESTIMATE (Not to Exceed):

HOURS: _____2640__________ DOLLARS: $ __750,000.00_______

6. CONTRACING OFFICER REPRESENTATIVE

NAME:___DTRA STEP COR____________

PHONE: _(555) 555-5555__ EMAIL: __NAME@MAIL.MIL____

7. CONTRACTOR POC

NAME:____________________________________________________________________

PHONE: __________________ EMAIL: _______________________________

8. DESCRIPTION OF TD (NOT TO EXCEED 1 PAGE):

The Government of Turkey (GoTU) has requested support of the United States Government for training technical personnel to survey and diagnose brucellosis in human, animal, and wildlife populations. The Defense Threat Reduction Agency (DTRA)

Cooperative Biological Engagement Program (CBEP) requests that the Contractor identify and engage up to four (4) appropriate researchers positioned within relevant ministries, institutes, or universities in Turkey to develop a collaborative biological research

(CBR) project proposal in partnership with a United States laboratory or university. It is the intention of the CBEP that this proposal be submitted to the Defense Threat Reduction Agency’s (DTRA) Fundamental Research Broad Agency Announcement

(BAA) Thrust Area 6. The proposal support should include assistance with hypothesis development, experimental design, project planning, finance, and risk mitigation. At a minimum, the proposed CBR should build capabilities, contribute to the country’s understanding of prevalence and distribution of brucellosis, leverage existing technical personnel at identified institutions or ministries, and ultimately result in peer-reviewed publications. The Contractor should not be included as an implementing collaborator for the proposed BAA project; however, the contractor is expected to provide mentorship and reach-back support to the implementing scientists in Turkey. Support is intended to be provided by up to two (2) mid-level subject matter experts (SME) in microbial pathogenesis. The period of performance should not exceed three years or a total cost of $750,000. The CBEP estimates this support will require 4 x 1-week trips by the SMEs to the region in Year 1 (4 trips x 2 people) and 2 x 1-week trips by the SMEs both in Year 2 and Year 3 (4 total trips x 2 people). Additional time is allotted for pre- and post-trip activities and follow-up actions and an additional 6 weeks of effort each year is allotted for coordination, document reviews, and reach-back support.

9a. PROPOSED SOLUTION (NOT TO EXCEED 2 PAGES):

9b. BUDGET (USE SEPARATE DOCUMENT FOR BUDGET BREAKDOWN:

COST CATEGORY TOTAL

LABOR $0

MATERIALS $0

TRAVEL $0

TOTAL $0.00

9c. TD SOLUTION BASIS OF ESTIMATE – DESCRIPTION (NOT TO EXCEED 2 PAGES):

10. FUNDING AUTHORIZED THIS TD REV:

COST CATEGORY COST POP START POP END

LABOR -$

MATERIALS

TRAVEL

TOTAL -$

COMMENTS (OPTIONAL): D

R

11a. FUNDS AUTHORIZED FOR THIS TD REV:

11b. FUNDS AUTHORIZED INCLUSIVE OF ALL

REV:

12a. CURRENT PERIOD OF PERFORMANCE

12b. TD REV PERIOD OF PERFORMANCE

13. CONTRACTOR

Signature:________________________________________________

Date:___________________________

14. REGION

CENTCOM/TURKEY

15. TECHNICAL POINTS OF CONTACT

(i.e., Country Manager/Regional Lead/Science Manager, A&AS)

16. CONTRACTING OFFICER REPRESENTATIVE APPROVAL

Signature:________________________________________________

Date:_____________________

D R

2. Contractor – Full Company Name

3. Technical Directive Number

4. Technical Directive Title

5. Total Estimated Technical Directive - Hours and Dollars (Not to Exceed)

6. Contracting Officer Representative – Contact details

7. Contractor Point of Contact – Details

8. Description of the Technical Directive – Government Provided

9. Solution:

a. Proposed Solution: Contractor’s proposed solution (including approach, schedule, and risk analysis) for TD. Not to exceed 2 pages.

b. Budget: Contractor enter proposed quantity(ies) for TD completion by using the embedded Excel workbook.

c. Technical Directive Solution Basis of Estimate – Description: Contractor complete the BOE for proposed solution to TD. Not to exceed 2 pages.

10. Funding Authorized this TD: Identifies information for billing purposes

11. Funds Authorized

a. Funds Authorized for this TD Revision Exclusively

b. Funds Authorized inclusive of all Revisions, Cumulative Total

12. Period of Performance

a. Current

b. TD Rev POP

13. Contractor: Sign & Date

14. Region for Technical Directive

15. Contracting Officer Approval: Sign & Date

16. Contracting Officer Representative Approval: Sign & Date

D R