Foa_Content_of_RFA-DP-24-062 Final.pdf

Centers for Disease Control and Prevention

NATIONAL CENTER FOR CHRONIC DISEASE PREVENTION AND HEALTH

PROMOTION

Health Promotion and Disease Prevention Research Centers: 2024 Special Interest Project

Competitive Supplements (SIPS)

RFA-DP-24-062

03/04/2024

Table of Contents Section I. Funding Opportunity Description

Section II. Award Information

Section III. Eligibility Information

Section IV. Application and Submission Information

Section V. Application Review Information

Section VI. Award Administration Information

Section VII. Agency Contacts

Section VIII. Other Information

Overview Participating Organization(s) Centers for Disease Control and Prevention Components of Participating Organizations Components of Participating Organizations:

National Center for Chronic Disease Prevention and Health Promotion Notice of Funding Opportunity (NOFO) Title Health Promotion and Disease Prevention Research Centers: 2024 Special Interest Project Competitive Supplements (SIPS) Activity Code U48

Notice of Funding Opportunity Type New Agency Notice of Funding Opportunity Number

RFA-DP-24-062

Assistance Listings Number(s) 93.135 Category of Funding Activity HL - Health NOFO Purpose This Notice of Funding Opportunity (NOFO) will provide supplemental funding to the CDC Health Promotion and Disease Prevention Research Centers (RFA-DP-24-004) to conduct Special Interest Research Projects (SIP) to inform public health practice. Recipients will conduct high-quality applied health promotion and disease prevention research in real-world settings to identify, design, test, assess, evaluate, disseminate, and translate interventions (i.e., programs, practices, policies, or strategies) to prevent and reduce risk for the leading causes of illness, disability, and death in the United States.

Key Dates Publication Date:

To receive notification of any changes to RFA-DP-24-062, return to the synopsis page of this announcement at www.grants.gov and click on the "Send Me Change Notification Emails" link.

An email address is needed for this service.

Letter of Intent Due Date:

02/02/2024 Publication Date:

12/15/2023

Letter of Intent Due Date:

02/05/2024

Application Due Date:

03/04/2024 Application Due Date:

03/04/2024

On-time submission requires that electronic applications be error-free and made available to CDC for processing from the NIH eRA system on or before the deadline date. Applications must be submitted to and validated successfully by Grants.gov no later than 11:59 PM U.S. Eastern Time.

Applicants will use a system or platform to submit their applications through Grants.gov and eRA Commons to CDC. ASSIST, an institutional system to system (S2S) solution, or Grants.gov Workspace are options. ASSIST is a commonly used platform because it provides a validation of all requirements prior to submission and prevents errors.

For more information on accessing or using ASSIST, you can refer to the ASSIST Online Help Site at: https://era.nih.gov/erahelp/assist. Additional support is available from the NIH eRA Service desk via http://grants.nih.gov/support/index.html.

• E-mail: commons@od.nih.gov

• Phone: 301-402-7469 or (toll-free) 1-866-504-9552

• Hours: Monday - Friday, 7 a.m. to 8 p.m. Eastern Time, excluding Federal holidays

Note: HHS/CDC grant submission procedures do not provide a grace period beyond the application due date time to correct any error or warning notices of noncompliance with application instructions that are identified by Grants.gov or eRA systems (i.e., error correction window).

Scientific Merit Review:

04/25/2024 Secondary Review:

https://www.grants.gov/ http://grants.nih.gov/support/index.html mailto:commons@od.nih.gov

06/24/2024 Estimated Start Date:

09/30/2024 Expiration Date:

03/05/2024 Required Application Instructions It is critical that applicants follow the instructions in the How to Apply - Application Guide except where instructed to do otherwise in this NOFO. Conformance to all requirements (both in the Application Guide and the NOFO) is required and strictly enforced. Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions.

Note:The Research Strategy component of the Research Plan is limited to 18 pages.

Page Limitations: Pages that exceed the page limits described in this NOFO will be removed and not forwarded for peer review, potentially affecting an application's score.

Applications that do not comply with these instructions may be delayed or may not be accepted for review.

Telecommunications for the Hearing Impaired: TTY 1-888-232-6348

For this specific NOFO, the Research Strategy component of the Research Plan narrative is limited to 12 pages, except for applications to both Component A AND B of a thematic network, which are limited to 18 pages for the Research Strategy.

Supporting materials for the Research Plan narrative included as appendices may not exceed 10 PDF files with a maximum of 30 pages for all appendices. Pages that exceed page limits described in this NOFO will be removed and not forwarded for peer review, potentially affecting an application's score.

Executive Summary Purpose: This Notice of Funding Opportunity (NOFO) invites applications from CDC Health Promotion and Disease Prevention Research Centers (PRCs), selected for funding under RFA- DP-24-004, to apply for supplemental funding to conduct Special Interest Research Projects (SIPs) to inform public health practice. PRCs will conduct high-quality applied health promotion and disease prevention research projects in real-world settings to identify, design, test, evaluate, disseminate, and translate interventions (i.e., programs, practices, policies, or strategies) to prevent and reduce risk for the leading causes of illness, disability, and death in the United States.

Mechanism of Support: Cooperative Agreement

Funds Available and Anticipated Number of Awards: The estimated total funding (including direct and indirect costs) for the period of performance (9/30/2024 - 9/29/2029) is $36,075,000.

It is anticipated that up to 28 awards will be made under this NOFO. Awards issued under this NOFO are contingent upon the availability of funds and receipt of a sufficient number of meritorious applications. Because the nature and scope of the proposed research projects will https://grants.nih.gov/grants/how-to-apply-application-guide.html vary from application to application, it is anticipated that the total amount awarded, and the number of awards will depend upon the quality and cost of the applications.

• Budget and Project Period. The estimated total funding (direct and indirect) for the first 12-month budget period, 9/30/2024 - 9/29/2025, is $8,775,000. See Section VIII. Other Information - Special Interests Project Descriptions for the funding amount and project period for each individual SIP.

• Application Research Strategy Length: Page limits for the Research Strategy are clearly specified in Section IV. Application and Submission Information of this announcement.

• Eligible Institutions/Organizations. Institutions/organizations listed in Section III.

Eligibility Information are eligible to apply.

• Eligible Project Directors/Principal Investigators (PDs/PIs). Individuals with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their institution/organization to develop an application for support.

• NOTE: CDC does not make awards to individuals directly, only to institutions / organizations. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply.

• Number of PDs/PIs. The SIP PI/PD may be anyone that meets the qualifications from within the selected recipient PRC institution (RFA-DP-24-004). The PI/PD named on RFA-DP-24-004 Notice of Award MUST be included as a Co-PI on the SIP, if not already proposed as the SIP PI/PD. Additional SIP PIs/PDs are permitted, but they also must be referred to as SIP Co-PIs/PD.

• Number of Applications. Applicants may apply to more than one SIP listed in Section VIII: Other Information - Special Interests Project Descriptions; however, a separate application is required for each SIP. Only one application per SIP per institution is allowed (e.g., multiple applications for the same SIP (listed in Section VIII) from the same institution are NOT permitted). Each SIP application, and SF 424 (R&R) must be submitted as a New Application (field 8) and must include the correct SIP number in Field 4.a (Federal Identifier), and the SIP Title Field 4.b (Agency Routing Identifier), as listed below and in Section VIII. Special Interest Project Descriptions. PLEASE NOTE:

Effective April 4, 2022, applicants must have a Unique Entity Identifier (UEI) at the time of application submission. The UEI replaced the Data Universal Numbering System (DUNS) and is generated as part of SAM.gov registration. Current SAM.gov registrants have already been assigned their UEI and can view it in SAM.gov and Grants.gov. Additional information is available on the GSA website, SAM.gov, and Grants.gov-Finding the UEI.

• Application Type. New

• Special Date(s). The Pre-Application Informational Call will be scheduled in early 2024.

Call-in information will be provided on the CDC PRC home page (Prevention Research Centers | CDC)

• Application Materials. See Section IV: Application and Submission Information for application materials.

• Hearing Impaired: Telecommunications for the hearing impaired are available at: TTY:

1-888-232-6348 https://www.gsa.gov/about-us/organization/federal-acquisition-service/office-of-systems-management/integrated-award-environment-iae/iae-systems-information-kit/unique-entity-identifier-update https://sam.gov/content/home https://grantsgovprod.wordpress.com/2021/09/14/how-to-find-an-applicants-uei-within-grants-gov/ https://grantsgovprod.wordpress.com/2021/09/14/how-to-find-an-applicants-uei-within-grants-gov/ https://www.cdc.gov/prc/ https://www.cdc.gov/prc/

Section I. Funding Opportunity Description Statutory Authority The activities of this NOFO are supported under Section 1706 of the Public Health Service Act, as amended (42 USC 300u-5). The eligible applicants (academic research centers) are further defined in Section 799B of the Public Health Service Act (42 USC 295p). Funding for this activity is current through the Consolidated Appropriations Act 2023, Joint Explanatory Statement on H.R. 2617.

1. Background and Purpose Prevention research includes applied public health research (to develop and evaluate health promotion and disease prevention and control strategies that are community- and population-based). It can involve identifying strategies to inform the design of interventions, testing developed interventions for efficacy and effectiveness, or conducing dissemination and implementation research to increase understanding of strategies to implement and sustain interventions in public health practice. Applied public health promotion and disease prevention research may focus on primary, secondary, or tertiary prevention; or may improve health and prevent disease through approaches that involve changes to individual behavior, policy or environmental structure, health systems, or socio-economic factors. Applied public health researchers engage communities and key partners to conduct high-quality research that supports the development and evaluation of health promotion and disease prevention interventions, dissemination of new science, and translation of proven effective interventions into public health practice and policy for population health benefit.

The Prevention Research Center (PRC) Program was established by Congress in 1984 (Public Law 98-551) to conduct research in health promotion, disease prevention, and methods of appraising health hazards and risk factors. Congress mandated that the centers be located at academic health centers capable of providing multidisciplinary faculty with expertise in public health, relationships with professionals in other relevant fields, graduate training and demonstrated curricula in disease prevention, and a capability for residency training in public health or preventive medicine. The PRCs also serve as demonstration sites for the use of new and innovative applied public research and activities for disease prevention and health promotion.

CDC administers the PRC Program and provides leadership, technical assistance, and oversight.

Funded PRCs can compete for Special Interest Research Projects (SIPs) sponsored by CDC, HHS, and other federal agencies, to conduct research and other activities in priority areas to inform public health practice.

CDC created the SIP program in 1993 as a supplemental funding mechanism to support health promotion and disease prevention research that would benefit from a multidisciplinary group of researchers. SIPs are supplemental funding awards that focus on topics of interest or gaps in knowledge or research and can also support the development of state and local public health interventions and policies. PRCs are uniquely positioned to oversee, coordinate, and rapidly initiate applied public health research that promotes the field of health promotion and disease prevention due to their established relationships with multidisciplinary faculty and community partners. SIP topics are aligned with public health priorities, such as the Healthy People 2030 Objectives—HHS’s national objectives for improving Americans’ health. SIPs are sponsored and primarily funded by CDC Centers, Institutes, and Offices (CIOs).

https://www.whitehouse.gov/briefing-room/legislation/2022/12/29/bill-signed-h-r-2617/

SIPs can focus on various topics or a gap in scientific evidence, such as:

• Major causes of death and disability in the United States.

• Improving public health practice within communities.

• Cultivating effective state and local public health programs.

• Developing and evaluating disease prevention and health promotion interventions.

• Disseminating new science and translating proven effective prevention interventions into public health practice and policy for community-wide benefit.

SIPs can have different structures including funding one or multiple PRCs to conduct community-based applied prevention research projects:

• Single PRC: The SIP supports one PRC to conduct a specific research project.

• Multiple PRCs: The SIP supports two or more PRCs to conduct different dimensions of a research project or to test strategies in different populations.

• Thematic Research Networks: The SIP supports multiple PRCs that collaborate on research of a specific health issue.

Institutions (successful PRC applicants) selected for funding under RFA-DP-24-004 are encouraged to apply for SIPs that expand and strengthen their PRC's mission and increase their applied public health research activities to contribute to preventing and reducing risk for the leading causes of illness, disability, and death in the United States.

Healthy People 2030 and other National Strategic Priorities The 2024 SIP research activities align with following the Healthy People 2030 topic areas:

Arthritis, Cancer, Environmental Health, Epilepsy, Health Care, Health Communications, Maternal Infant Child Health, Mental Health and Mental Disorders, Nutrition, Physical Activity, People with Disabilities, and Vaccination/Immunizations.

Below are the HP 2030 health topics and the associated SIPs:

Arthritis:

• Arthritis Management and Well-being Research Network: (A-01, A-02, A-03, A-04)

People with Disabilities (includes Epilepsy)

• Managing Epilepsy Well Network (MEW) (MHMD, HC)

Cancer:

• Understanding the needs of Ovarian Cancer Survivors (C-11, C-R01)

• Survivorship care plans and mortality among adult cancer survivors (C-11, C-R01)

• Cancer Prevention and Control Research Network (C1-C11))

• Gauging men’s reaction to relabeling of GG1 prostate cancer and understanding of pathology reports (C-08, C-R01)

• Understanding the impact of reducing social isolation and loneliness on health indices among cancer survivors (C-R01)

Health Communications:

https://health.gov/healthypeople/search?query=Arthritis&f%5B0%5D=content_type%3Ahealthy_people_objective https://health.gov/healthypeople/objectives-and-data/browse-objectives/people-disabilities https://health.gov/healthypeople/objectives-and-data/browse-objectives/mental-health-and-mental-disorders https://health.gov/healthypeople/objectives-and-data/browse-objectives/health-care-access-and-quality https://health.gov/healthypeople/objectives-and-data/browse-objectives/cancer https://health.gov/healthypeople/search?query=HIT-04

• Mental Health and Chronic Disease Prevention Network (HIT-04)

Nutrition:

• Nutrition Obesity Policy Research and Evaluation Network (NWS-01, NWS-04, NWS-

06, NWS-08, NWS-09, NWS-10, MICH15-16)

Physical Activity:

• Physical Activity Policy and Evaluation Research Network (PA01, PA-02, PA-06, PA- 10, PA-11, EH02 and EVP06)

Immunizations:

• Advancing Research in Immunization Services Network (IID-02-11, IID-D01-IID-D03)

Vaccinations:

• Assessment of perceptions and effectiveness of interventions to increase MMR vaccination among children in close-knit communities with longstanding vaccine hesitancy (IID-02, IID-03, IID-04)

• Understanding the potential of schools in promoting non-mandated childhood vaccinations (IID-07, IID-08, IID-09)

Additional information on specific HP2030 and other National Strategic Priorities are described for each Special Interest Project in Section VIII. Other Information, Special Interests Project Descriptions.

Public Health Impact Accomplishing the objectives of these projects will result in improvements in the delivery and outcomes of public health programs and practice. The PRCs will use equitable and participatory evidence-based, community-engaged approaches to 1) fill critical gaps in chronic disease prevention and health promotion research, and 2) identify effective strategies to reduce or eliminate health disparities and health inequities. Public Health Impact is described for each Special Interest Project in Section VIII. Other Information, Special Interest Project Descriptions.

Relevant Work As appropriate, this information will be provided for each SIP in the individual descriptions contained in Section VIII. Other Information - Special Interests Project Descriptions of this announcement.

2. Approach As appropriate, the information that follows (up to Section II. Award Information) will be provided for each SIP in the individual descriptions contained in Section VIII. Other Information - Special Interests Project Descriptions.

Special Interests Project descriptions in this announcement will include:

• Objectives/Outcomes

• Public Health Priorities

• Study design and methods https://health.gov/healthypeople/search?query=Nutrition&f%5B0%5D=content_type%3Ahealthy_people_objective https://intranet.cdc.gov/ofr/grants/grantsolutions/announcement-module-2/help-guides.html https://health.gov/healthypeople/search?query=Immunizations&f%5B0%5D=content_type%3Ahealthy_people_objective&page=0 https://health.gov/healthypeople/search?query=IID&f%5B0%5D=content_type%3Ahealthy_people_objective

• Target Population

• Collaboration/Partnerships

• Recruitment Plan

• Annual Action Plan

• Evaluation/Performance Measurement

• Data Management Plan

• Dissemination and Translation Plan

• Public Health Impact

• References

See individual SIPS proposals in the Section VIII. Other Information - Special Interests Project Descriptions for more detailed information of the requirements of each research projects.

SIP recipients may be asked to participate in the PRC Program Evaluation Reporting System (PERS) to collect data that are used to evaluate Special Interest Projects, CDC Award Management Platform (AMP), or other CDC-led program evaluation data collection activities/systems (e.g., success stories, newsletters, issue briefs, and PRC profiles, and the Pathway to Practice resource center).

Objectives/Outcomes Recipients are expected to achieve expective objectives and outcomes during the reporting/funding period as described in Section VIII. Other Information - Special Interest Project Descriptions.

Target Population Applicants should clearly identify the population and communities they will address in the Research Plan as described for each SIP in Section VIII. Other Information - Special Interest Project Descriptions.

Collaboration/Partnerships It is anticipated that Recipients will collaborate internally and with external partners (organizations, individuals, community members, governmental, non-governmental and private sector partners) on SIP projects. Additional information on specific collaborations/partnership are described for each SIP in Section VIII. Other Information - Special Interest Project Descriptions.

Evaluation/Performance Measurement Recipients may be asked to report data and information to CDC to support monitoring and evaluation activities, as described for each SIP in Section VIII. Other Information - Special Interest Project Descriptions.

Translation Plan Applicants will be expected to describe how the results from the research will be adopted by other institutions or implemented and sustained by partners that translate after project completion, as described for each SIP in Section VIII. Other Information - Special Interest Project Descriptions.

3. Funding Strategy N/A

Section II. Award Information Funding Instrument Type:

CA (Cooperative Agreement) A support mechanism used when there will be substantial Federal scientific or programmatic involvement. Substantial involvement means that, after award, scientific or program staff will assist, guide, coordinate, or participate in project activities.

Application Types Allowed:

New - An application that is submitted for funding for the first time. Includes multiple submission attempts within the same round.

Estimated Total Funding:

$36,075,000 Estimated BY Funding:

$8,775,000 (direct and indirect costs) for the first budget year.

Estimated Total Funding:

$36,075,000 (direct and indirect costs) for the entire period of performance.

Anticipated Number of Awards:

It is anticipated that 28 awards will be funded under this NOFO in the first year of funding.

Estimated BY Funding:

$8,775,000 (direct and indirect costs) for the first budget year.

Estimated Total Funding:

$36,075,000 (direct and indirect costs) for the entire period of performance.

Awards issued under this NOFO are contingent on the availability of funds and submission of a sufficient number of meritorious applications.

Award Ceiling:

$675,000 Per Budget Period

Award Floor:

$0 Per Budget Period

Total Period of Performance Length:

60-month project period with five 12-month budget periods. year(s)

Throughout the Period of Performance, CDC's commitment to continuation of awards will depend on the availability of funds, evidence of satisfactory progress by the recipient (as documented in required reports), and CDC’s determination that continued funding is in the best interest of the Federal government.

HHS/CDC grants policies as described in the HHS Grants Policy Statement (https://www.hhs.gov/sites/default/files/grants/grants/policies-regulations/hhsgps107.pdf) will apply to the applications submitted and awards made in response to this NOFO.

If you are successful and receive a Notice of Award, in accepting the award, you agree that the award and any activities thereunder are subject to all provisions of 45 CFR Part 75, currently in effect or implemented during the period of the award, other Department regulations and policies in effect at the time of the award, and applicable statutory provisions.

Section III. Eligibility Information

1. Eligible Applicants Eligibility Category:

25 (Others (see text field entitled "Additional Information on Eligibility" for clarification))

2. Foreign Organizations Foreign Organizations are not eligible to apply.

Foreign components of U.S. Organizations are not eligible to apply.

For this announcement, applicants may not include collaborators or consultants from foreign institutions. All applicable federal laws and policies apply.

3. Additional Information on Eligibility Applicants must be approved for funding under CDC Notice of Funding Opportunity RFA-DP- 24-004 Health Promotion and Disease Prevention Research Centers in order to apply for SIP supplemental funding under this announcement. On the SIP applicant's SF424 (R&R), the institution's legal name, EIN, and UEI (sections 8a, b and c of SF424) must match the information of the institution selected for funding under RFA-DP-24-004 as listed in the Notice of Award. Special eligibility may apply to each SIP that will be listed in the NOFO.

Competition is limited to the 20 institutions approved for funding under CDC RFA-DP-24-004 as CDC Prevention Research Centers (PRCs). The institutions currently approved for funding are:

CDC Grant # PRC Recipient U48 DP006809 Emory University U48 DP006803 Georgia State University U48 DP006785 Harvard School of Public Health U48 DP006802 Morehouse School of Medicine U48 DP006778 New York University School of Medicine https://www.hhs.gov/sites/default/files/grants/grants/policies-regulations/hhsgps107.pdf

U48 DP006816 San Diego State University U48 DP006799 University of Arizona U48 DP006814 University of Arkansas for Medical Sciences U48 DP006806 University of California, San Francisco U48 DP006812 University of Iowa U48 DP006808 University of Massachusetts Medical School Worcester U48 DP006791 University of Michigan at Ann Arbor U48 DP006787 University of Minnesota U48 DP006807 University of North Carolina at Chapel Hill U48 DP006801 University of Pennsylvania U48 DP006792 University of Pittsburgh U48 DP006779 University of Rochester U48 DP006780 University of South Carolina at Columbia U48 DP006789 University of Utah U48 DP006793 University of Wisconsin-Madison

4. Justification for Less than Maximum Competition Competition is limited to recipients funded under RFA-DP-24-004 because they are uniquely positioned to perform, oversee, and coordinate applied public health promotion and chronic disease prevention research due to their established relationships with community partners.

5. Responsiveness For an application to be considered it must be responsive to the information below:

• Submitted by an institution currently approved for funding as a CDC PRC under CDC

RFA-DP-24-004.

• The institution name and EIN of the SIP applicant must match the information of the institution funded under RFA-DP-24-004 as listed in the Notice of Award, SF424 R&R, Section 8a. and b.

• Special eligibility requirement(s) may apply to each SIP as listed in Section VIII. Other Information - Special Interest Project Descriptions of the NOFO announcement.

• If an application is incomplete or does not meet the responsiveness criteria in the special eligibility requirements listed in this section, it will be deemed non-responsive and will not enter into the peer review process.

If an application is incomplete or does not meet the responsiveness criteria in the special eligibility requirements listed in this section or in Section VIII. Other Information - Special Interest Project Descriptions, it will be deemed non-responsive and will not enter into the peer review process.

6. Required Registrations Applicant organizations must complete the following registrations as described in the SF 424 (R&R) Application Guide to be eligible to apply for or receive an award. Applicants must have a valid Unique Entity Identifier (UEI) number in order to begin each of the following registrations.

PLEASE NOTE: Effective April 4, 2022, applicants must have a Unique Entity Identifier (UEI) at the time of application submission. The UEI replaced the Data Universal Numbering System (DUNS) and is generated as part of SAM.gov registration. Current SAM.gov registrants have already been assigned their UEI and can view it in SAM.gov and Grants.gov. Additional information is available on the GSA website, SAM.gov, and Grants.gov-Finding the UEI.

• (Foreign entities only): Special Instructions for acquiring a Commercial and Governmental Entity (NCAGE) Code: NCAGE Tool / Products / NCS Help Center (nato.int).

• System for Award Management (SAM) – must maintain current registration in SAM (the replacement system for the Central Contractor Registration) to be renewed annually, SAM.gov.

• Grants.gov

• eRA Commons

All applicant organizations must register with Grants.gov. Please visit www.Grants.gov at least 30 days prior to submitting your application to familiarize yourself with the registration and submission processes. The one-time registration process will take three to five days to complete.

However, it is best to start the registration process at least two weeks prior to application submission.

All Senior/Key Personnel (including Program Directors/Principal Investigators (PD/PIs) must also work with their institutional officials to register with the eRA Commons or ensure their existing Principal Investigator (PD/PI) eRA Commons account is affiliated with the eRA commons account of the applicant organization. All registrations must be successfully completed and active before the application due date. Applicant organizations are strongly encouraged to start the eRA Commons registration process at least four (4) weeks prior to the application due date. ASSIST requires that applicant users have an active eRA Commons account in order to prepare an application. It also requires that the applicant organization's Signing Official have an active eRA Commons Signing Official account in order to initiate the submission process.

During the submission process, ASSIST will prompt the Signing Official to enter their Grants.gov Authorized Organizational Representative (AOR) credentials in order to complete the submission, therefore the applicant organization must ensure that their Grants.gov AOR credentials are active.

7. Universal Identifier Requirements and System for Award Management (SAM) All applicant organizations must obtain a Unique Entity Identifier (UEI) number as the Universal Identifier when applying for Federal grants or cooperative agreements. The UEI number is a twelve-digit number assigned by SAM.gov. An AOR should be consulted to determine the appropriate number. If the organization does not have a UEI number, an AOR should register through SAM.gov. Note this is an organizational number. Individual Program Directors/Principal Investigators do not need to register for a UEI number.

Additionally, organizations must maintain the registration with current information at all times during which it has an application under consideration for funding by CDC and, if an award is https://www.gsa.gov/about-us/organization/federal-acquisition-service/office-of-systems-management/integrated-award-environment-iae/iae-systems-information-kit/unique-entity-identifier-update https://sam.gov/content/home https://grantsgovprod.wordpress.com/2021/09/14/how-to-find-an-applicants-uei-within-grants-gov/ https://grantsgovprod.wordpress.com/2021/09/14/how-to-find-an-applicants-uei-within-grants-gov/ https://eportal.nspa.nato.int/Codification/Support/en/Products/NCAGE/ https://eportal.nspa.nato.int/Codification/Support/en/Products/NCAGE/ https://sam.gov/content.gov https://grants.gov https://public.era.nih.gov/commons https://www.Grants.gov made, until a final financial report is submitted or the final payment is received, whichever is later.

SAM.gov is the primary registrant database for the Federal government and is the repository into which an entity must provide information required for the conduct of business as a recipient.

Additional information about registration procedures may be found at SAM.gov and the SAM.gov Knowledge Base.

If an award is granted, the recipient organization must notify potential sub-recipients that no organization may receive a subaward under the grant unless the organization has provided its UEI number to the recipient organization.

8. Eligible Individuals (Project Director/Principal Investigator) in Organizations/Institutions Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Project Director/Principal Investigator (PD/PI) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for HHS/CDC support.

9. Cost Sharing This NOFO does not require cost sharing as defined in the HHS Grants Policy Statement (http://www.hhs.gov/sites/default/files/grants/grants/policies-regulations/hhsgps107.pdf).

10. Number of Applications As defined in the HHS Grants Policy Statement, (https://www.hhs.gov/sites/default/files/grants/grants/policies-regulations/hhsgps107.pdf), applications received in response to the same Notice of Funding Opportunity generally are scored individually and then ranked with other applications under peer review in their order of relative programmatic, technical, or scientific merit. HHS/CDC will not accept any application in response to this NOFO that is essentially the same as one currently pending initial peer review unless the applicant withdraws the pending application.

Applicants may apply to more than one SIP listed in Section VIII: Other Information - Special Interest Project Descriptions; however, a separate application is required for each SIP. Only one application per SIP per institution is allowed (e.g., multiple applications for the same SIP (listed in Section VIII) from the same institution are NOT permitted). Each SIP application, and SF 424 (R&R) must be submitted as a New Application (field 8) and must include the correct SIP number in Field 4.a (Federal Identifier), and the SIP Title Field 4.b (Agency Routing Identifier), as listed below and in Section IX. Special Interest Project Descriptions.

The SIP PI/PD may be anyone that meets the qualifications from within the selected recipient PRC institution (RFA-DP-24-004 Core Award). The PI/PD named on RFA-DP-24-004 Notice of Award MUST be included as a Co-PI on the SIP, if not already proposed as the SIP PI/PD.

Additional SIP PIs/PDs are permitted but must be referred to as SIP Co-PI/PD.

Section IV. Application and Submission Information https://sam.gov/content/home https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.fsd.gov%2Fgsafsd_sp%3Fid%3Dgsa_kb_view2%26kb_id%3Df66d8e6cdb76d4100d73f81d0f9619c6&data=04%7C01%7Ccshifflett%40dminc.com%7C8eee7a2adab549a3b3c008d925e9a364%7Cdb7ac9ef779d46e59bca00509580ad6b%7C0%7C0%7C637582507851821018%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=UrR%2B%2FM2wWF2fZG05Z8O6JS2C3FXXSl%2F7B3%2FB45XHRrg%3D&reserved=0

1. Address to Request Application Package Applicants will use a system or platform to submit their applications through Grants.gov and eRA Commons to CDC. ASSIST, an institutional system to system (S2S) solution, or Grants.gov Workspace are options. ASSIST is a commonly used platform because, unlike other platforms, it provides a validation of all requirements prior to submission and prevents errors.

To use ASSIST, applicants must visit https://public.era.nih.gov where you can login using your eRA Commons credentials, and enter the Notice of Funding Opportunity Number to initiate the application, and begin the application preparation process.

If you experience problems accessing or using ASSIST, you can refer to the ASSIST Online Help Site at: https://era.nih.gov/erahelp/assist. Additional support is available from the NIH eRA Service desk via: http://grants.nih.gov/support/index.html

• Email: commons@od.nih.gov

• Phone: 301-402-7469 or (toll-free) 1-866-504-9552.

Hours: Monday - Friday, 7 a.m. to 8 p.m. Eastern Time, excluding Federal holidays.

2. Content and Form of Application Submission Applicants must use FORMS-G application packages for due dates on or before January 24, 2023 and must use FORMS-H application packages for due dates on or after January 25, 2023.

Application guides for FORMS-G and FORMS-H application packages are posted to the How to Apply - Application Guide page.

It is critical that applicants follow the instructions in the SF-424 (R&R) Application Guide How to Apply - Application Guide except where instructed in this Notice of Funding Opportunity to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review. The package associated with this NOFO includes all applicable mandatory and optional forms. Please note that some forms marked optional in the application package are required for submission of applications for this NOFO. Follow the instructions in the SF-424 Application Guide to ensure you complete all appropriate “optional” components.

When using ASSIST, all mandatory forms will appear as separate tabs at the top of the Application Information screen; applicants may add optional forms available for the NOFO by selecting the Add Optional Form button in the left navigation panel.

Please use the form and instructions for SF 424 (R&R) FORMS-H for applications due on or after January 25, 2023.

3. Letter of Intent Due Date for Letter Of Intent 02/02/2024

02/02/2024 Due Date for Letter Of Intent (LOI) 02/02/2024 https://public.era.nih.gov http://grants.nih.gov/support/index.html https://grants.nih.gov/grants/how-to-apply-application-guide.html https://grants.nih.gov/grants/how-to-apply-application-guide.html https://grants.nih.gov/grants/how-to-apply-application-guide.html

Although a letter of intent (LOI) is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows CDC staff to estimate the potential review workload and plan the peer review.

By the date listed above and in Part 1. Overview Information, prospective applicants are asked to submit an LOI electronically that includes the following information:

• Name of Institution Submitting Application

• SIP number and title

• Descriptive title of proposed SIP

• Name, address, and telephone number of the Lead PD/PI for the SIP Application

• Participating institutions, if applicable

• Number and title of this notice of funding opportunity: RFA-DP-24-0062: Health

Promotion and Disease Prevention Research Centers -2024 Special Interest Projects (SIPS) Competitive Supplements

The LOI should be emailed to the CDC Scientific Program Official with subject line “NOFO RFA-DP-24-062” and the SIP proposal number which applicant will apply (i.e., SIP 24-001).

Natalie Darling, MPH Scientific Program Official Extramural Research Program Operations and Services (ERPOS) Email: researchnofo@cdc.gov

4. Required and Optional Components A complete application has many components, both required and optional. The forms package associated with this NOFO in Grants.gov includes all applicable components for this NOFO, required and optional. In ASSIST, all required and optional forms will appear as separate tabs at the top of the Application Information screen.

5. PHS 398 Research Plan Component The SF424 (R&R) Application Guide includes instructions for applicants to complete a PHS 398 Research Plan that consists of components. Not all components of the Research Plan apply to all Notices of Funding Opportunities (NOFOs). Specifically, some of the following components are for Resubmissions or Revisions only. See the SF 424 (R&R) Application Guide at How to Apply

- Application Guide for additional information. Please attach applicable sections of the following Research Plan components as directed in Part 2, Section 1 (Notice of Funding Opportunity Description).

Follow the page limits stated in the SF 424 unless otherwise specified in the NOFO. As applicable to and specified in the NOFO, the application should include the bolded headers in this section and should address activities to be conducted over the course of the entire project, including but not limited to:

1. Introduction to Application (for Resubmission and Revision ONLY) - provide a clear description about the purpose of the proposed research and how it addresses the specific requirements of the NOFO.

2. Specific Aims – state the problem the proposed research addresses and how it will result in public health impact and improvements in population health.

mailto:researchnofo@cdc.gov

3. Research Strategy – the research strategy should be organized under 3 headings:

Significance, Innovation and Approach. Describe the proposed research plan, including staffing and time line.

4. Progress Report Publication List (for Continuation ONLY)

Other Research Plan Sections

5. Vertebrate Animals

6. Select Agent Research

7. Multiple PD/PI Leadership Plan.

8. Consortium/Contractual Arrangements

9. Letters of Support

10. Resource Sharing Plan(s)

11. Authentication of Key Biological and/or Chemical Resources

12. Appendix

All instructions in the SF424 (R&R) Application Guide at How to Apply - Application Guide must be followed along with any additional instructions provided in the NOFO.

Applicants that plan to collect public health data must submit a Data Management Plan (DMP) in the Resource Sharing Plan section of the PHS 398 Research Plan Component of the application.

A DMP is required for each collection of public health data proposed. Applicants who contend that the public health data they collect or create are not appropriate for release must justify that contention in the DMP submitted with their application for CDC funds.

The DMP may be outlined in a narrative format or as a checklist but, at a minimum, should include:

• A description of the data to be collected or generated in the proposed project;

• Standards to be used for the collected or generated data;

• Mechanisms for, or limitations to, providing access to and sharing of the data (include a description of provisions for the protection of privacy, confidentiality, security, intellectual property, or other rights - this section should address access to identifiable and de-identified data);

• Statement of the use of data standards that ensure all released data have appropriate documentation that describes the method of collection, what the data represent, and potential limitations for use; and

• Plans for archiving and long-term preservation of the data, or explaining why long-term preservation and access are not justified (this section should address archiving and preservation of identifiable and deidentified data).

CDC OMB approved templates may be used (e.g. NCCDPHP template https://www.cdc.gov/chronicdisease/pdf/nofo/DMP-Template-508.docx)

Other examples of DMPs may be found here: USGS, http://www.usgs.gov//products/data-and-tools/data-management/data-management-plans

Applicants must use FORMS-G application packages for due dates on or before January 24, 2023 and must use FORMS-H application packages for due dates on or after January 25, 2023.

Application guides for FORMS-G and FORMS-H application packages are posted to the How to Apply - Application Guide page.

Consortium/Contractual Arrangements: Subcontracts may not exceed 50% of the total award.

Please use the form and instructions for SF424 (R&R) FORM-H for applications due on or after January 25, 2023.

6. Appendix Do not use the appendix to circumvent page limits. A maximum of 10 PDF documents are allowed in the appendix. Additionally, up to 3 publications may be included that are not publicly available. Follow all instructions for the Appendix as described in the SF424 (R&R) Application Guide.

7. Page Limitations All page limitations described in this individual NOFO must be followed. For this specific NOFO, the Research Strategy component of the Research Plan narrative is limited to 18 pages.

Supporting materials for the Research Plan narrative included as appendices may not exceed 10 PDF files with a maximum of 30 pages for all appendices. Pages that exceed page limits described in this NOFO will be removed and not forwarded for peer review, potentially affecting an application's score.

8. Format for Attachments Designed to maximize system-conducted validations, multiple separate attachments are required for a complete application. When the application is received by the agency, all submitted forms and all separate attachments are combined into a single document that is used by peer reviewers and agency staff. Applicants should ensure that all attachments are uploaded to the system.

CDC requires all text attachments to the Adobe application forms be submitted as PDFs and that all text attachments conform to the agency-specific formatting requirements noted in the SF424 (R&R) Application Guide at .How to Apply - Application Guide.

Applicants must use FORMS-G application packages for due date on or before January 24, 2023 and must use FORMS-H application packages for due dates on or after January 25, 2023.

Application guides for FORMS-G and FORMS-H application packages are posted to the How to Apply - Application Guide page.

https://www.cdc.gov/chronicdisease/pdf/nofo/DMP-Template-508.docx http://www.usgs.gov//products/data-and-tools/data-management/data-management-plans http://www.usgs.gov//products/data-and-tools/data-management/data-management-plans https://grants.nih.gov/grants/how-to-apply-application-guide.html https://grants.nih.gov/grants/how-to-apply-application-guide.html https://grants.nih.gov/grants/how-to-apply-application-guide.html

Please use the form and instructions for SF424 (R&R) FORMS-H for applications due on or after January 25, 2023.

9. Submission Dates & Times Part I. Overview Information contains information about Key Dates. Applicants are strongly encouraged to allocate additional time and submit in advance of the deadline to ensure they have time to make any corrections that might be necessary for successful submission. This includes the time necessary to complete the application resubmission process that may be necessary, if errors are identified during validation by Grants.gov and the NIH eRA systems. The application package is not complete until it has passed the Grants.gov and NIH eRA Commons submission and validation processes. Applicants will use a platform or system to submit applications.

ASSIST is a commonly used platform because it provides a validation of all requirements prior to submission. If ASSIST detects errors, then the applicant must correct errors before their application can be submitted. Applicants should view their applications in ASSIST after submission to ensure accurate and successful submission through Grants.gov. If the submission is not successful and post-submission errors are found, then those errors must be corrected and the application must be resubmitted in ASSIST.

Applicants are able to access, view, and track the status of their applications in the eRA Commons.

Information on the submission process is provided in the SF-424 (R&R) Application Guidance and ASSIST User Guide at https://era.nih.gov/files/ASSIST_user_guide.pdf.

Note: HHS/CDC grant submission procedures do not provide a grace period beyond the grant application due date time to correct any error or warning notices of noncompliance with application instructions that are identified by Grants.gov or eRA systems (i.e., error correction window).

Applicants who encounter problems when submitting their applications must attempt to resolve them by contacting the NIH eRA Service desk at:

Toll-free: 1-866-504-9552; Phone: 301-402-7469 http://grants.nih.gov/support/index.html Hours: Mon-Fri, 7 a.m. to 8 p.m. Eastern Time (closed on Federal holidays)

Problems with Grants.gov can be resolved by contacting the Grants.gov Contact Center at:

Toll-free: 1-800-518-4726 https://www.grants.gov/web/grants/support.html support@grants.gov Hours: 24 hours a day, 7 days a week; closed on Federal holidays

It is important that applicants complete the application submission process well in advance of the due date time.

After submission of your application package, applicants will receive a "submission receipt" email generated by Grants.gov. Grants.gov will then generate a second e-mail https://era.nih.gov/files/ASSIST_user_guide.pdf http://grants.nih.gov/support/index.html https://www.grants.gov/web/grants/support.html mailto:support@grants.gov message to applicants which will either validate or reject their submitted application package. A third and final e-mail message is generated once the applicant's application package has passed validation and the grantor agency has confirmed receipt of the application.

Unsuccessful Submissions: If an application submission was unsuccessful, the applicant must:

1. Track submission and verify the submission status (tracking should be done initially regardless of rejection or success).

a. If the status states "rejected," be sure to save time stamped, documented rejection notices, and do #2a or #2b

2. Check emails from both Grants.gov and NIH eRA Commons for rejection notices.

a. If the deadline has passed, he/she should email the Grants Management contact listed in the Agency Contacts section of this announcement explaining why the submission failed.

b. If there is time before the deadline, correct the problem(s) and resubmit as soon as possible.

Due Date for Applications 03/04/2024

03/04/2024 Electronically submitted applications must be submitted no later than 11:59 p.m., ET, on the listed application due date.

10. Funding Restrictions Expanded Authority:

For more information on expanded authority and pre-award costs, go to https://www.hhs.gov/sites/default/files/grants/grants/policies-regulations/hhsgps107.pdf and speak to your GMS.

All HHS/CDC awards are subject to the federal regulations, in 45 CFR Part 75, terms and conditions, and other requirements described in the HHS Grants Policy Statement.