FAQs HRSA-26-052.pdf

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​Sickle Cell Disease Regional Care Excellence (SoRCE) Program
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HRSA-26-052
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This is a Frequently Asked Questions document for HRSA 26-052, the Sickle Cell Disease Regional Care Excellence (SoRCE) Program, dated June 26, 2026. The funding opportunity has a four-year project period running from September 1, 2026, through August 31, 2030, with annual budget periods from September 1 through August 31. Each Regional Coordinating Hub (RCH) must contract with at least three Clinical-Community Spokes (CCSs), where each CCS consists of one clinical center partnered with at least one community-based organization (CBO). These three CCSs must account for at least 40% of the RCH's budget, with remaining funds available to support other clinical sites in the region without CBO partnerships. Within six months of award, RCHs must develop a regional action plan to support partnership and collaboration across all CCSs.

Subawards do not need to be established before application submission if supporting documents such as Letters of Support or Memoranda of Understanding clearly describe the roles and deliverables of subrecipients and contractors. The optional SoRCE emerging issues supplement does not count toward the page limit and provides one-time, one-year funding up to $250,000 per year, with supplements awarded based on objective review scores in order of ranking. Applicants must submit biographical sketches (maximum two pages each) for all key personnel listed in the Staffing Plan and Job Descriptions. The document clarifies that individuals are not eligible applicants, and the NOFO does not specify whether entities can serve as subawards on multiple applications.

FAQs HRSA-26-052.pdf

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HRSA-26-052 TA Call Presentation.pdf PDF
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FAQs - SoRCE Questions_6.11.26.pdf PDF
HRSA-26-052 Final.pdf PDF
HRSA-26-052 Final.pdf PDF

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FAQs – Sickle Cell Disease Regional Care Excellence Program (SoRCE)

HRSA 26-052

Date: 6/26/2026

Q: What is the project period for HRSA 26-052, the Sickle Cell Disease Regional Care Excellence (SoRCE) Program funding opportunity?

A: The project period is four years, starting on 9/1/2026 and ending on 8/31/2030.

Q: Can one CBO partner with three other clinical sites to meet the Clinical Community Spoke (CCS) requirements for the region?

A: See page 5 of the NOFO (see Program Structure section): Each Regional Coordinating Hub (RCH) must contract with at least three Clinical-Community Spokes (CCSs) in their region. Each CCS includes one clinical center partnered with at least one community-based organization (CBO).

See page 39 of the NOFO: The panel reviewing NOFO applications will look to see how well applications describe plans to reach every person with Sickle Cell Disease (SCD) in the region through at least three CCSs.

Q: Do subawards have to be established before our application is submitted?

A: No. If you include documents that confirm actual or pending contracts or agreements (e.g., Letter of Support, Memorandum of Understanding, etc.), the documents should clearly describe the roles of subrecipients and contractors and any deliverables. It is not necessary to include the entire contents of lengthy agreements, so long as the portions you include describe the working relationship between you and the other (See pg. 34 of the NOFO under Attachment 5 for more information).

Please note that within six months, the RCH must develop a regional action plan to support partnership, collaboration, and resource sharing across all CCSs in the region. (See page 13 of the NOFO).

Q: Does the SoRCE emerging issues supplement count towards the page limit?

A: No. The SoRCE emerging issues supplement does not count towards the page limit.

There was an error on page 24 of the NOFO. Attachment 7: SoRCE emerging issues supplement (optional) does not count towards the page limit.

Q: How is the supplement awarded?

A: Depending on the availability and appropriation of funds, supplemental funding may be awarded in any of the four project years. If applicants are interested in receiving supplemental funds, they must include their supplement application as part of their initial application. These are one time, one-year supplements for up to $250,000 per year.

Supplements will be funded in the order of the objective review score earned by the applicant in the base competition. Please see page 34 of the NOFO for more information.

https://www.grants.gov/search-results-detail/360997

Q: After meeting the CCS requirement to contract with at least three Clinical- Community Spokes (CCSs) in the region, can we provide funds to clinical sites in our region that do not have a partnership with a CBO?

A: Yes. See page 5 of the NOFO (see Program Structure section): Each Regional Coordinating Hub (RCH) must contract with at least three Clinical-Community Spokes (CCSs) in their region. After meeting the requirement to have contracts with at least 3 CCCs in your region accounting for at least 40% of your budget, the remaining part of your budget can support other clinical sites in your region that do not have a partnership with a Community-Based Organization (CBO).

Q: Can you tell me whether another organization in my region has submitted an application?

A: No. We are not able to provide that information.

Q: Could you confirm the period of performance and budget period dates?

A: The correct period of performance is four years, starting on 9/1/2026 and ending on 8/31/2030. The budget period is 9/1 - 8/31 each year. Please note there was an error in the period of performance and budget period dates on pg. 7 of the NOFO.

Q: Can we include NIH biographical sketches within the application?

A: Yes. You can submit an NIH biographical sketch for people who will hold key positions as described in Attachment 2: Staffing Plan and Job Descriptions. Each biographical sketch should be no longer than two pages. Please see page 33 (Attachment 3: Biographical Sketches) for more information.

Q: Can we include biographical sketches for all the key personnel listed in my application or should we include a curriculum vitae (CV) for all the key personnel listed in my application?

A: You should provide a biographical sketch for all key positions you describe in Attachment 2: Staffing Plan and Job Descriptions.

Q: I have sickle cell disease, and I would like to get a link for the available funding opportunity.

A: Here is a link to the funding opportunity. Please see page 7 (Eligibility and Types of Eligible Organizations) and note that individuals are not eligible applicants under this NOFO. Please see page 9 of the NOFO under Completeness and Responsiveness Criteria for more information about types of eligible organizations

Q: The NOFO states that an institution can only have one submission. Can a subaward location be listed on more than one application?

The NOFO does not specify whether an entity can serve as a subaward on more than one application.

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