Exhibit B - Agency Specific Requirements.pdf

Agency Specific Requirements 1 | Pa g e Initials: Offeror: Gov’t:

EXHIBIT B

Agency Specific Requirements – Chapel Hill, NC The Environmental Protection Agency (EPA)

The Agency Specific Requirements (ASRs) do not reduce the minimum requirements contained within the Lease. These ASRs provides specific agency requirements, which may be complementary, more specific, or more stringent than those of the Lease minimum requirements.

1. SPACE REQUIREMENTS

Rentable square feet (RSF) for a new lease may not exceed 19,061 rentable square feet of office space and must be within a Minimum ANSI-BOMA (ABOA) SF of 16,575 to a Maximum of 17,404 ABOA SF office space. This EPA leased spaces will include enclosed offices, office support, laboratories, and laboratory support spaces.

ANSI-BOMA (ABOA) is described as: “the area where a tenant normally houses personnel and/or furniture, for which a measurement is to be computed.”

2. DELINEATED AREA

North: I-40 East: I-40 to Route 54 South: Route 54 to US-501 West: Route 86

3. ROOM SCHEDULE

The room schedule is based on ANSI-BOMA (ABOA) SF, which represents the Government’s approximate expected workspace. EPA leased spaces include enclosed offices of four different size ranges constituting about 5,270 net USF; office support conference rooms totaling about 520 net USF;

laboratories covering 8,663 net USF; and laboratory support of 2,122 net USF. The following exhibit on the next page provides a summary of the EPA administered spaces.

4. ADDITIONAL REQUIREMENTS

• 2 reserved parking spaces exclusive use of the Government and 44 surface/outside parking spaces, unreserved for employee and visitors.

• Must have facility access and operational control to air quality exposure testing chambers and supporting infrastructure in which the Agency would provide operational and maintenance support.

Also there is a need for touchdown space for the chambers O&M contracted support.

• Must have extensive freezer room for sample storage.

• Must have an existing infrastructure for database and high computing systems.

• Must be within proximity to a hospital system for immediate clinical and research support, emergency care services, and Magnetic Resonance Imaging (MRI) capabilities.

• Must have facility access to loading docks, IT and telecommunication rooms, bottled gas and chemical waste rooms, and on-site diesel generator.

APRIL 2024

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Exhibit 3: Summary of EPA Administered Spaces1

Type Descr iption Count net USF Type Type Count net

USF

Off ice Spaces Off ice Suppor t Spaces Standard Office 120 31 3,720 Conference Room 260 2 520 Medium Office 180 2 360 Large Office 220 4 880 Executive Office 310 1 310

Subtotal 38 5,270 Subtotal: Off ice and Off ice Suppor t 5,790

Type Descr iption

Current Room Nos.

net USF Type Descr iption

Current Room Nos.

net

USF

Laborator ies Laboratory Suppor t

AEROSOL DOSIMETRY 1 237 466 AUTOCLAVE 417 229

AEROSOL DOSIMETRY 2 243 467 AUTOCLAVE 419 139

BIOCHEMISTRY 441 695 COLD RM. 449 229

CHROMATOGRAPHY 207 468 COMP. RM. 231 112

CLINICAL ANALYTIC LAB 201 704 DRY CHEMICAL 417A 86

CLINICAL PHYSIOLOGY LAB 211 222 IMAGING LAB. 431 233

CLINICAL ASSESSMENT LAB 227 128 EQUIPMENT STORAGE B47 201

COMMON EQUIPMENT RM 213 221 FREEZER ROOM B48 893

COMMON EQUIPMENT RM 411 464 Subtotal: Laboratory Suppor t 2,122

DOSIMETRY 235 222

FLOW CYTOMETRY 401 233

ICP MASS 219 360

IN-VITRO EXPOSURE 501 482

LABELING 447 223

MOLECULAR SIGNALING LAB 403 684

MOLECULAR BIOLOGY LAB 433 691

P2 LAB. 409 56

P2 LAB. 409A 167

PARTICLE 245 473

SONICATION 415 220

TISSUE CULTURE NORTH 215 344

TISSUE NEUROPHYSIOLOGY 233 220

TISSUE CULTURE SOUTH 249 235

TISSUE CULTURE LAB 439 218

Subtotal: Laboratory 8,663 GRAND TOTAL 16,575

Avg. Unit S ize

Avg. Unit S ize

1 All noted areas are net usable square feet and does not include circulation and other common areas.

Offeror:________ Gov't:________

PROGRAM OF REQUIREMENTS HUMAN STUDIES FACILITY, CHAPEL HILL, NC

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A. Office Spaces

Note that the HSF is an existing facility, and no immediate renovations or modifications are anticipated. The following provides suggested office space requirements. EPA intends to use existing office spaces within the HSF.

Standard Offices ...................................................................................... 31 x 120 net USF

The standard office will be equipped with a workspace with an adjustable height table, secondary work surface, task chair, and workspace storage for the occupant.

Storage may include a wardrobe. Provide LED task lighting for the occupant.

Provide two guest chairs.

ARCHITECTURAL

Walls & Special Finishes: Drywall deck to ceiling, painted.

Glazed interior partition

Door: Stained wood, STC 30

Ceiling: Standard.

Lighting: Overhead fixtures 30FC + 20FC task lighting.

MEP | A/V | IT

Mechanical: No more than three private offices in the same thermal zone.

All spaces in the thermal zone must have the same solar orientation.

Electrical: (3) 20A duplex outlets

(1) switch type vacancy sensor with dimming control.

General purpose outlets.

Data/IT: (2) data outlets Wireless access

Equipment: To be determined during design development

Medium Offices ........................................................................................ 2 x 180 net USF

The medium offices will require a workspace with an adjustable height table, secondary work surface, task chair, and workspace storage for the occupant.

Storage will include a wardrobe. Provide LED task lighting for the occupant.

Provide two guest chairs. A small meeting table for 2-3 people is also required.

ARCHITECTURAL

Walls & Special Finishes: Drywall deck to ceiling, painted.

Glazed interior partition

Door: Stained wood, STC 30

Ceiling: Standard.

Lighting: Overhead fixtures 30FC + 20FC task lighting.

MEP | A/V | IT

Mechanical: No more than three private offices in the same thermal zone.

All spaces in the thermal zone must have the same solar orientation.

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APRIL 2024 DRAFT POR

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Electrical: (4) 20A duplex outlets

(1) switch type vacancy sensor with dimming control.

General purpose outlets.

Data/IT: (3) data outlets Wireless access

Equipment: To be determined during design development

Large Offices ............................................................................................. 4 x 220 net USF

The large office will require a workspace with an adjustable height table, secondary work surface, task chair, and workspace storage for the occupant. Storage will include a wardrobe. Provide LED task lighting for the occupant. Provide two guest chairs. Provide a meeting table for 4-5 people, preferably with a wall monitor with AV projection capabilities.

ARCHITECTURAL

Walls & Special Finishes: Drywall deck to ceiling, painted.

Glazed interior partition

Door: Stained wood, STC 30

Ceiling: Standard.

Lighting: Overhead fixtures 30FC + 20FC task lighting.

MEP | A/V | IT

Mechanical: No more than three private offices in the same thermal zone.

All spaces in the thermal zone must have the same solar orientation.

Electrical: (6) 20A duplex outlets

(1) switch type vacancy sensor with dimming control.

General purpose outlets.

AV 55” Wall monitor Projection capability

Data/IT: (3) data outlets Wireless access

Equipment: To be determined during design development

Executive Offices ........................................................................................ 1 x 310 net USF

The executive office will be an enclosed room, preferably with slab-to-slab partitions. It will require a workspace with an adjustable height table, secondary work surface, task chair, and workspace storage for the occupant. Storage will include a wardrobe. Provide LED task lighting for the occupant. Provide two guest chairs. Provide a meeting area with a table for 6-8 people, and a wall monitor with AV projection capabilities.

ARCHITECTURAL

Walls & Special Finishes: Drywall deck to ceiling, painted.

Glazed interior partition

Door: Stained wood, STC 30

Ceiling: Standard.

Lighting: Overhead fixtures 30FC + 20FC task lighting.

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MEP | A/V | IT

Mechanical: No more than three private offices in the same thermal zone.

All spaces in the thermal zone must have the same solar orientation.

Electrical: (8) 20A duplex outlets

(1) switch type vacancy sensor with dimming control.

General purpose outlets.

AV 55” Wall monitor Projection capability

Data/IT: (4) data outlets Wireless access

Equipment: To be determined during design development

B. Office Support Spaces

Note that the HSF is an existing facility, and no immediate renovations or modifications are anticipated. The following provides suggested conference space requirements.

Conference ............................................................................................... 2 x 260 net USF

These conference rooms will be for EPA’s exclusive use and are to be provided in proximity to other EPA administered spaces. The rooms are to have standard office finishes, network access for participants, audiovisual projection, and video-teleconference (VTC) capabilities. Furniture includes a table, credenza, and seating for 12 people.

ARCHITECTURAL

Walls & Special Finishes: High STC wall Preferably slab-to-slab construction

Flooring: Carpet tile

Ceiling: High NC

Lighting: Standard.

MEP | A/V | IT

Mechanical: Provide independent zone control.

Electrical: 6” Fire rated poke-thru devices with (4) 5-20R Outlets and (4) RJ45 jacks centered under table

(1) Recessed power and data connection behind each wall mounted monitor.

General purpose 20A duplex receptacles.

(1) Vacancy sensor

Data/IT: Wireless access

Audiovisual: Wall monitor Projection capability Room reservation display

Equipment: Wall mounted monitor(S)

ADJACENCIES

Conveniently accessible to all floor occupants

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C. Laboratories

The following sections provide the room numbers and brief descriptions of the laboratories within the existing HSF. No immediate renovations or modifications are anticipated.

Aerosol Dosimetry 1 ........................................................................................ 466 net USF Rm 237

This laboratory is utilized to provide aerosol dosimetry data for large sized particles using unique inhalation testing equipment. Typically, the laboratory houses up to three people and is in use 10-30 hours a week. The room is required to be in proximity to the dosimetry development room where techniques are developed.

Aerosol Dosimetry 2 ........................................................................................ 467 net USF Rm 243

This laboratory is utilized to provide aerosol dosimetry data for large sized particles using unique inhalation testing equipment. Typically, the laboratory houses up to three people and is in use 30-40 hours a week. The room is required to be in proximity to the dosimetry development room where techniques are developed.

Biochemistry Lab ............................................................................................. 695 net USF Rm 441

This laboratory is utilized to perform experiments using biochemistry techniques.

Typically, the laboratory houses up to five people and is in use 30-40 hours a week. This room needs to be in close proximity to the tissue culture and molecular biology laboratories.

Chromatography ............................................................................................. 468 net USF Rm 207

This laboratory is utilized to perform analysis of clinical and non-clinical samples using chromatography. Typically, the laboratory houses up to two people and is in use 30-40 hours a week. The room is required to be proximate to clinical processing laboratories.

Clinical Analytic Lab ........................................................................................ 704 net USF Rm 201

This laboratory is utilized to perform analysis of clinical samples. Typically, the laboratory houses up to four people and is in use 30-40 hours a week. The room is required to be proximate to clinical processing laboratories.

Clinical Physiology Lab .................................................................................... 222 net USF Rm 211

This laboratory is utilized to process clinical samples such as urine for future analysis. Preparation of material for use in ex‐vivo. Typically, the laboratory houses up to two people and is in use 30-40 hours a week. This room is required to be proximate to where clinical samples are collected and processed.

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Clinical Assessment Lab .................................................................................. 128 net USF Rm 227

This laboratory performs clinical assessment tests such as methacholine challenge and sputum induction. Typically, the laboratory houses up to three people and is in use 30-40 hours a week. This room is required to be proximate to where clinical samples are collected and processed.

Common Equipment Room .............................................................................. 221 net USF Rm 213

This wet lab houses equipment that is shared by multiple investigators for multiple purposes. Typically, the space houses up to two persons and is in use 30-40 hours a week. This room is required to be proximate to 2nd floor labs and investigators that need equipment readily accessible.

Common Equipment Room .............................................................................. 464 net USF Rm 411

This wet lab houses equipment that is shared by multiple users. Typically, this lab houses up to two people and is in use 30-40 hours a week.

Dosimetry Development Lab ............................................................................ 222 net USF Rm 235

This instrument lab is used to develop dosimetry models and techniques. Typically, the lab houses up to one person and is in use 10-30 hours a week. This lab needs to be proximate to Aerosol Dosimetry Labs.

Flow Cytometry Lab ........................................................................................ 233 net USF Rm 401

This wet lab is utilized to prepare samples and perform Flow Cytometry. Typically, the laboratory houses up to three people and is in use 30-40 hours a week. This lab needs to be proximate to other labs for sample access.

ICP Mass Spectrometry .................................................................................... 360 net USF Rm 219

This wet lab is utilized to perform Inductively coupled mass spectrometry on clinical and non-clinical samples to measure metal content. Typically, the support space houses up to two people and is in use 30-40 hours a week. It is critical the lab be close to other laboratories where clinical samples are assayed or prepared.

In-Vitro Exposure System .................................................................................. 482 net USF Rm 501

This is an instrument lab. Typically, the lab houses up to six people and is in use 10-30 hours a week.

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Labeling Lab .................................................................................................... 223 net USF Rm 447

This wet lab is utilized to perform preparation and storage of laboratory specimens to be used in adjacent labs. Storage of specimens and reagents that are used in nearby labs. Typically, the laboratory houses up to one person and is in use 30-40 hours a week. It is critical this room be proximate to other labs using products of this lab.

Molecular Signaling Lab .................................................................................. 684 net USF Rm 403

This wet lab is utilized to perform analysis of molecular signaling pathways to study mechanisms of air pollutants. Typically, the laboratory houses up to four people and is in use 30-40 hours a week. It is critical this room be proximate to other labs for processing samples.

Molecular Biology Lab ...................................................................................... 691 net USF Rm 433

This wet lab is utilized to perform experiments using molecular biology techniques.

Typically, the laboratory houses up to three people and is in use 30-40 hours a week. Proximity to tissue culture laboratories for transfer of material is desirable.

P2 Lab ............................................................................................................... 56 net USF Rm 409

This lab support space is utilized to perform cell culture in a controlled environment- utilization of virus vectors. Typically, the space houses up to one person and is in use 30-40 hours a week.

P2 Lab ............................................................................................................. 167 net USF Rm 409A

This lab support space is utilized to perform cell culture in a controlled environment- utilization of virus vectors. Typically, the space houses up to one person and is in use 30-40 hours a week.

Particle Analysis Lab ........................................................................................ 473 net USF Rm 245

This lab support space is utilized to perform analysis of particle composition and biological effects on human cells. Typically, the space houses up to three people and is in use 30-40 hours a week. This room needs to be near other labs where clinical samples are assayed or prepared.

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Sonication ........................................................................................................ 220 net USF Rm 415

This lab support space is utilized to perform sonication of samples, including solutions with particles. Typically, the space houses up to one person and is in use 10-30 hours a week. It is critical that this room be proximate to labs where particle research is performed.

Tissue Culture North ........................................................................................ 344 net USF Rm 215

This lab support space is utilized to perform mechanistic studies using human cells under sterile conditions (maintenance and growth). Typically, the support space houses up to two people and is in use 30-40 hours a week. It is critical that this room be proximate to labs where clinical samples are assayed or prepared.

Tissue Neurophysiology Lab ............................................................................. 220 net USF Rm 233

This lab support space is utilized to perform neurophysiological assays on tissues.

Perform thin layer chromatography. Typically, the support space houses up to three people and is in use 30-40 hours a week. It is critical that this room be proximate to labs where clinical samples are assayed or prepared.

Tissue Culture South ........................................................................................ 235 net USF Rm 249

This lab support space is utilized to perform mechanistic studies using human cells under sterile conditions (Maintenance and growing of cells). Typically, the support space houses up to two people and is in use 30-40 hours a week. It is critical that this room be proximate to labs where clinical samples are assayed or prepared.

Tissue Culture Lab ............................................................................................ 218 net USF Rm 439

This lab support space is utilized to perform mechanistic studies using human cells under sterile conditions (Maintenance and growing of cells). Typically, the support space houses up to two people and is in use 30-40 hours a week. It is critical that this room be proximate to labs where clinical samples are assayed or prepared.

D. Laboratory Support Spaces

The following sections provide the room numbers and brief descriptions of the laboratory support spaces within the existing HSF. No immediate renovations or modifications are anticipated.

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Autoclave Labs ................................................................................... 229 and 139 net USF Rms 417and 419

These lab support spaces house autoclaves that sterilize equipment and material critical to maintain sterility in experiments and processes. Typically, the lab support space houses up to one person and is in use 30-40 hours a week. No critical adjacencies.

Cold Room ...................................................................................................... 229 net USF Rm 449

This lab support space houses walk‐in refrigerator where samples, media, and other supplies requiring storage at cool temperatures are maintained. Typically, the lab support space houses up to one person and is in use 30-40 hours a week. It is critical that this room be proximate to labs where clinical samples will need to be refrigerated.

Computer Room .............................................................................................. 112 net USF Rm 231

This support space provides non‐EPA network computer access to guests in HSF and provides access to UNC network. Typically, the lab support space houses up to one person and is in use 10-30 hours a week. No critical adjacencies.

Dry Chemical Storage ....................................................................................... 86 net USF Rm 417A

This support space stores chemicals that are non‐volatile or hazardous. Typically, the lab support space houses up to one person and is in use 30-40 hours a week.

Desirable to be close to other labs that need storage.

Imaging Lab .................................................................................................... 233 net USF Rm 431

This support space performs microscopy and cell imaging. Typically, the lab support space houses up to two persons and is in use 30-40 hours a week. It is critical this support space be close to tissue culture labs to transfer cells.

Equipment Storage ........................................................................................... 201 net USF Rm B47

Freezer Room .................................................................................................. 893 net USF Rm B48

This support space stores items needing to be frozen at all times. Desirable to be close to other labs that need freezer storage.

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4.2 Block and Stack of the EPA Leased Spaces

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Attachment 1: Floor Plans Depicting EPA Leased Spaces