DHHS-NIHAO2012066 - Amendment 3.pdf

AMENDMENT OF SOLICITATION / MODIFICATION OF

CONTRACT

1. CONTRACT ID CODE

PAGE OF PAGES

1 3

2. AMENDMENT/MODIFICATION NO.

3. EFFECTIVE DATE

09/17/2012

4. REQUISITION/PURCHASE REQ. NO

5. PROJECT NO.

(If applicable)

6. ISSUED BY

National Institutes of Health, NIAID, AMOB

CODE

7. ADMINISTERED BY

10401 Fernwood Road, MSC 4813 Bethesda, MD 20817

8. NAME AND ADDRESS OF CONTRACTOR (No., street, county, State and ZIP code)

All Potential Offerors

9A. AMENDMENT OF SOLICITATION NO.

DHHS-NIHAO2012066

9B. DATED (SEE ITEM 11)

August 15, 2007

10A. MODIFICATION OF CONTRACT/ORDER NO.

10B. DATED (SEE ITEM 13)

FACILITY CODE

11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS

The above numbered solicitation is amended as set forth in Item 14. The hour and date specified for receipt of Offers is extended is not extended.

Offerors must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the following methods: (a) By completing Items 8 and 15, and returning 1 copy of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer submitted; or (c) By separate letter or telegram which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGEMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by telegram or letter, provided each telegram or letter makes reference to the solicitation and this amendment, and is received prior to the opening hour and date specified.

12. ACCOUNTING AND APPROPRIATION DATA (If required)

13. THIS ITEM APPLIES ONLY TO MODIFICATIONS OF CONTRACTS/ORDERS

IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14.

A. THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify Authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT ORDER NO. IN ITEM 10A.

B. THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as changes in paying office, appropriation data, etc.) SET

FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY

C. THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:

D. OTHER (Specify type of modification and authority)

E. IMPORTANT: Contractor is not, is required to sign this document and return copy to the issuing office.

14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, including solicitation/contract subject matter where feasible)

This amendment provides responses to questions posed by potential Offerors

Offeror is hereby directed that:

Proposals for furnishing the supplies and/or services in THE SCHEDULE of subject RFP DHHS-NIHAO2012066 will be received at the place specified in, and in the number of copies specified, until 10:00 am local time on September 28, 2012.

Offers will be valid for 120 days unless a different period is specified by the offeror on the Attachment entitled, "Proposal Summary and Data Record, NIH 2043” provided with the RFP.

Please review the Federal Business Opportunities website (www.fedbizopps.gov) for additional information.

15A. NAME AND TITLE OF SIGNER (Type or print)

16A NAME AND TITLE OF CONTRACTING OFFICER (Type or print)

Daniel J. Hartinger, Contracting Officer

15B. CONTRACTOR/OFFEROR

(Signature of person authorized to sign)

15C. DATE SIGNED

16B. UNITED STATES OF AMERICA

(Signature of person authorized to sign)

16C. DATE SIGNED

NSN 7540-01-152-8070

PREVIOUS EDITION UNUSABLE

30-105

STANDARD FORM 30 (Rev. 10-83) Prescribed by GSA

FAR (48 CFR) 53.243

http://www.fedbizopps.gov/

RFP DHHS-NIHAO2012066 Amendment 3

RESPONSE TO QUESTIONS

Responses to Offeror’s questions are posed in a question (Q) and answer (A) format as follows Q1. A1.

Additional questions will be responded to in later amendments as necessary.

Q1. The SOW calls out the need for the contractor to provide necessary facilities and staff to segregate and derive off-spring from serological positive founder breeders. Will sero positive founder breeders definitely be coming along with the colony if awarded? What is the likelihood of sero positive animals being awarded with the SPF animals?

A1. Currently there are no non-SPF animals, and there are no plans at this time to incorporate non-SPF animals. Over the past several years there has been a less than 3% sero conversation rate within the colony. Within the past year, less than 1%.

Q2. Instructions for the business proposal state that all costs to complete the statement of work should be included in the per diem rate. Does this include testing during the initial quarantine period when the animals arrive, as well as the more extensive annual testing/vaccinations required? Can these occasional extra testing requirements be billed out separately at the time of service?

A2. The testing, frequency and proposed testing laboratory of all serological testing should be outlined clearly, and all cost should be incorporated within the per diem rate

Q3. Please provide the rate of serologic conversion to a positive status for the viral pathogens HBV, SIV, SRV-D, STLV-1 that may exist in the NIAID colonies.

A3. See Q1.

Q4. Are there non-SPF founder breeders in the current population?

A4. Not at this time. See Q1.

Q5. Are infants in the colonies included in this solicitation derived to maintain SPF status, or are they mother-reared in their natal social groups?

A5. Currently mother reared. The Offeror should outline within its proposal any mean and methods that are proposed.

Q6. The contract specifies juvenile SPF non-human primates. What are the specific age or weight parameters for research use (1, 2, and/or 3 years of age)?

A6. 2-3yrs of age

Q7. What is the general demographic breakdown of the existing NIAID colony/colonies?

A7. A representative sample of the colony demographic is included in the SOW. Final determination will be made on task order award. The demographic of each colony will be based on strategic planning needs, as well as, current compatible groups.

RFP DHHS-NIHAO2012066 Amendment 3

Q8. Will this contract likely include the importation of non-SPF rhesus macaques by the

Government?

A8. This is not planned at this time, but if the need arises, the mean and methods to segregate animals described should be described within the proposal.

Q9. Will you provide an Annual Report for 2011/2012 including the reproductive statistics and activities of the SPF breeder population including:

a. Effective Breeder Population

b. Pregnancy Rate Based on Demographics

c. Fetal (premature) Death Rate

d. Live Birth Rate

e. Infant (less than 1 year) Death Rate

f. Production Rate (based on females 4+ years of age).

A9. Historical information of current NIAID colonies is not requested within this RFP and is not a basis for review. The Offeror should use the sample demographic provided in the RFP and should outline its experiences and statistics with similar breeding colonies.

Q10. We request to receive current demographics for the colony including:

g. Effective Breeder population-Prime (5 years+)

h. Sub-adult ( 4 years)

i. Juvenile (3 years)

j. Juvenile (2 years)

k. Yearling (1 year)

l. Total Males and Total Females for each age category

m. Pre-weanlings

n. Total for each age category and pre-weanlings.

A10. A representative sample of the colony demographic is included in the SOW. The actual colony demographic will be determined upon Task Order award. See Q7.

Q11. We would like to know the number of animals in each group and the age/sex breakdown for each of the social groups.

A11. Currently, 7-12 animals are maintained in a family group. The actual demographic of the colony will be determined upon Task Order award. See Q7

AMENDMENT OF SOLICITATION / MODIFICATION OF CONTRACT