D_Attachment 1 - Purchase Description_MQ.pdf

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

Brand Name or Equal: Milli-Q® IQ 7003 Water Purification System

1. Statement of Need and Purpose:

The National Institute of Neurological Disorders and Stroke (NINDS) requires a new brand-name or equal Milli-Q® IQ 7003 Water Purification System to replace the broken system, which was damaged in a flood at NIH Building 35 in Dec. 2022.

2. Background Information and Objective:

The National Institutes of Health (NIH) is an agency of the Department of Health and Human Services and the Federal focal point for health research. Its mission is to seek fundamental knowledge about the nature and behavior of living systems and apply that knowledge to enhance health, lengthen life, and reduce illness and disability.

The NINDS, which is an Institute within the NIH, seeks to reduce the burden of neurological disease through supporting and conducting basic, translational, and clinical research on the healthy and diseased nervous system, fostering the training of investigators in the basic and clinical neurosciences, and seeking better understanding, diagnosis, treatment, and prevention of neurological disorders.

The synaptic communication between the millions of neurons in the human brain is what allows it to function normally. Understanding the chemical basis of synaptic transmission under normal and abnormal circumstances is the aim of NINDS’ Synaptic Transmission Section, which investigates the molecular mechanisms underlying SNARE complex formation and interaction in cultured neurons from the hippocampus and adrenal medulla.

This section’s research could help in the diagnosis and treatment of prevalent neurological conditions like Alzheimer's disease.

The fields of synaptic transmission and exocytosis research will both benefit from a quality ultrapure water source. A high-quality and reliable ultrapure water source is crucial for NINDS’ research as without it, cell culture, molecular, and biochemistry experiments would be impossible to perform.

3. Generic Name of Product:

Water Purification System

4. Purchase Description:

• Brand name or Equal benchmark: Milli-Q® IQ 7003 Water Purification System

• Manufacturer’s name: EMD Millipore Corporation

5. Salient characteristics The required equipment must meet or exceed the following minimum salient physical, functional, and performance characteristics:

• Must have the ability to produce Type I ultrapure water.

• Must provide easy Volumetric Water Dispensing, with ultrapure water flow rates adjustable from drop-by-drop to 2 L/min.

• Complete process monitoring system systematically must check water temperature, pressure, and conductivity, using calibrated meters at different steps.

• The ultrapure water system must be able to recirculate water to maintain high water quality during periods of non-use.

• Must be able to select a Unique Range of Final Polishers, to adapt to specific application(s). Millipak (bacteria removal), Biopak (to remove RNAse, DNAse, and Pyrogens), LC Pak for production of UHPLC or LC-MS grade water.

• To avoid maintenance errors and to improve traceability, the internal primary consumable water purification cartridges must have a built-in RFID tag

• Must include 5” capacitive touch screen interface that allows easy interaction with system and provides pertinent data, including step-by-step graphical maintenance protocols.

• Must include low voltage DC pump (<50 decibels at 1m) for virtually silent operation

• The ability to accurate Temperature Measurement of +/- 0.1 degrees Celsius to improve the precision of Temperature Compensation at 25 degrees C

• Must include extensive service software program thereby providing all pertinent service information

• The system must have built-in mercury-free, Xenon eximer UV lamps with a two-year life time, emission at 172 nm and 265 nm wavelengths for oxidation and bactericidal functions.

• The ability to purify water in a first step using unique Jetpore ion-exchange resin, synthetic activated carbon, and UV lamp at 185 nm to reach a resistivity of 18.2 MΏ.cm at 25◦C and a TOC value <5ppb. Monitored by advance analytical techniques.

• The ability for the system to give a TOC result from an A10 TOC monitor that is calibrated to international norms and standards.

6. Quantity: Please see below table for required quantities of all brand name or equal items:

Item Number

Item Description Quantity Destination

1 Water purification system 1 Shipped to Building 35 2 Storage tank frame 25 L 1 Shipped to Building 35 3 Country box IQ 70XX US 1 Shipped to Building 35 4 Storage tank top assembly 1 Shipped to Building 35 5 Q-POD® remote dispenser 1 Shipped to Building 35 6 Connector 2m System-Tank 1 Shipped to Building 35 7 Connector 2m System-POD 1 Shipped to Building 35

8 Water sensor 1 Shipped to Building 35 9 External solenoid valve 1 Shipped to Building 35 10 PACK SUPPORT 2 TUBES 2 GAUGES 1 Shipped to Building 35

11 PREPAK 1 PRETREATMENT PACK

2/box 1 Shipped to Building 35

12 Purification pack kit 1 Shipped to Building 35 13 Biopak® polisher 4 Shipped to Building 35 14 EfferSan Effervescent Tablets Qty 24 1 Shipped to Building 35 15 Installation 1 Shipped to Building 35 16 TRAVEL ZONE 1 1 Shipped to Building 35 17 StartPAK installation pack 1 Shipped to Building 35

7. Delivery Date:

8 weeks after receipt of order

8. Delivery Requirements: The Contractor shall deliver the required equipment in coordination with Government officials. Delivery must be FOB Destination and must include inside installation. The equipment shall be delivered and installed between the hours of 8:00am and 5:00pm, Bethesda, MD local prevailing time, Monday through Friday.

PURCHASE DESCRIPTION