Combined_syn_sol PCA-NIEHS-04776.docx

Hospital and Laboratory Support Division Office of Logistics and Operations (OLAO) Office of Acquisition and Logistics Management (OALM)

Title: 800 MHz NMR Console and Probe

Combined Synopsis Solicitation

Synopsis No. 75N98026Q01180-04776

COMBINED SYNOPSIS / SOLICITATION WORKFORM

Action Code: Combined Synopsis/Solicitation Date: September 09 Year: 2026 Contracting Office Zip Code: 20892 Classification Code: 6640 Contracting Office Address:

6701 Rockledge Drive Bethesda, MD 20817 Subject/Title: 800 MHz NMR Console and Probe Solicitation Number: 75N98026Q01180-04776 Closing Response Date: September 21, 2026 at 8:00 A.M. Eastern Daylight Time (EDT) Questions Due Date: September 14, 2026 at 8:00 A.M Eastern Daylight Time (EDT) Contact Point(s): Luz Casey, Program Specialist/Contract Specialist Contract Award Type: Firm Fixed Price Contract Award: TBD Contract Award Dollar Amount: TBD Contract Line Item Number(s): TBD Contractor Award Date: TBD Contractor Name: TBD Brand Name or Equal Acquisition (FAR 52.211-6): Yes Place of Contract Performance: Bethesda, MD Set-aside Status: N/A Description of Requirement: The National Institute of Environmental Health Sciences (NIEHS) Genomics Core (NGC) utilizes the Bruker Spatial Biology nCounter Pro System to perform experiments that assess gene expression changes in biological samples. The continued operation, reliability, and performance of this instrument are essential to supporting ongoing research activities.

The primary objective of this contract is to acquire new upgraded equipment for the NMR Research Core Facility of the Division of Intramural Research, NIEHS, NIH based on research requirements determined by the Institute. The 800 MHz NMR system requires upgrades to maintain it in good working order for research conducted at NIEHS. The required system will interface with the existing 800 MHz Agilent 4K Compact magnet at NIEHS. The system will include in generalized terms: a new 4 channel console designed primarily for biomolecular NMR and interfaces, a new room temperature probe, a new helium cooled probe with required accessories, and potentially and HR-MAS probe. The system will need to interface with a temperature controlled automated sample changer.

NMR CONSOLE AVANCE NEO-X 800 MHZ SB

Bruker system characteristics (unified AQS/BSMS):

- 80 MHz system clock, 12.5ns timing resolution

- Synchronicity on all channels within 12.5ns

- Gradient control for all Bruker gradient amplifiers

- Up to 8 RF channels

- Up to 4 trigger inputs with 12.5ns resolution

- Up to 4 real time output controls with 12.5ns resolution

- Ultra-stable, ultra-low noise B0 current source (LOCK)

- 2G Digital NMR Lock for 2H and/or 19F nuclei (LOCK, L-TRV)

- Bruker Shim current sources (SCB20)

- Bruker SmartVT control for up to 4 independent VT channels

- Bruker High Resolution gradient amplifiers (e.g. GAB/3) Bruker preamplifier system (HPPR) supports:

- Up to 8 RF preamplifiers

- Fully Multi-receive, no extra wiring/components

- Touch screen based human machine interface

- Accurate tuning and matching with factory calibrated preamplifiers

- Fully integrated automatic tuning and matching with ATM probes

- Probe identification (PICS) interface Supported Units:

- Bruker SmartCoolers (e.g. BCU-I)

- Bruker Low Temperature accessories (e.g. LN2 Exchanger)

- Bruker High Temperature equipment (e.g. BVTE3900)

- Bruker RT Shim Systems and BST Upperparts

Period of Performance: This is a one-time supply acquisition with the duration of the maintenance agreement as specified in the resulting contract or purchase order.

Place of Performance: Services shall be performed at the NIEHS Genomics Core facility where the nCounter Pro System is installed, unless remote technical support is sufficient to resolve the issue.

Vendor shall provide manufacturer-authorized maintenance, service, technical support, and any necessary repairs for the nCounter Pro System. Services shall include preventive maintenance, troubleshooting, software and firmware updates (as applicable), replacement of manufacturer-approved parts, and technical assistance required to maintain the instrument in optimal operating condition. All services shall be performed by Bruker Spatial Biology-trained personnel using manufacturer-approved procedures and components to ensure the system continues to meet original performance specifications.

The Contractor shall provide all resources necessary to accomplish the tasks and deliverables described in this Statement of Work (SOW). Subject to prior approval of the Contracting Officer (CO), the Contractor may acquire the services of a subcontractor and/or consultants to provide specialized services if deemed appropriate and within scope by the COR.

The Contractor shall employ a technical approach, utilize organizational resources, and implement management controls to achieve the cost, schedule, and performance requirements throughout the execution of the Contract Requirements. The Contractor shall be responsible for providing, managing, and overseeing its personnel, as well as any subcontractor/consultant efforts used in the performance of the Contract Requirements.

This is intended to be a firm-fixed price contract.

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.

The solicitation number is 75N98026Q01180-04776 and the solicitation is issued as a request for quote (RFQ). The solicitation document, the incorporated provisions, and clauses are those in effect through Federal Acquisition Circular 2024-07, effective August 29, 2024. This solicitation is being released unrestricted. The NAICS code is 334516. This requirement is not set aside for small business. This acquisition is being conducted in accordance with the procedures of FAR Part 12 and FAR Part 13. The Statement of Need and any terms and conditions relevant to the requirement are included as attachments. The provisions at FAR Clause 52.212-1, Instructions to Offerors – Commercial Items, applies to this acquisition. The following addendum related to the Instructions to Offerors is included:

Addendum to FAR Clause 52.212-1, Instructions to Offerors – Commercial Items. Please refer to this addendum for additional attachments, including the Statement of Work and other relevant information.

Evaluations will be conducted in accordance with the provision at FAR Clause 52.212-2. Offerors will be evaluated as follows: EVALUATION-COMMERCIAL ITEMS (OCT 2014) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate offers:

· Technical Proposal/Equipment Capability

· Equipment Warranty and Maintenance Coverage

· Delivery

· Price The Government will make award to the responsible vendor whose quote represents the lowest price technically acceptable, considering equipment capability, equipment warranty and maintenance coverage, delivery and price. The Government may select a higher-priced quote if it is determined that the additional technical merit or lower performance risk warrants the price premium.

Options. The Government will evaluate offers for award purposes by adding the total price for all options to the total price for the basic requirement. The Government may determine that an offer is unacceptable if the option prices are significantly unbalanced. Evaluation of options shall not obligate the Government to exercise the option(s). A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer’s specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award. Please refer to the addendum for additional evaluation information. Each Offeror must include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications – Commercial Items, with its offer.

Please note, each Offeror shall complete only paragraph (b) of this provision if the Offeror has completed the annual representations and certification electronically via the System for Award Management (SAM) website located at https://www.sam.gov/portal.

· FAR Clause 52.212-4, Contract Terms and Conditions – Commercial Items, applies to this acquisition. The terms and conditions outlined in the following addendum also apply:

· Addendum to FAR Clause 52.212-4, Contract Terms and Conditions – Commercial Items. Please refer to this addendum for additional terms and conditions related to the requirement.

· FAR Clause 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders – Commercial Items, applies to this acquisition. The full text version of FAR 52.212-5 included in the addenda as Attachment 5 indicate which FAR clauses and provisions are applicable to this acquisition.

Evaluation of Options Provision, The Government will evaluate offers for award purposes by adding the total price for all options to the total price for the basic award. This solicitation notified offerors that the award will include the Government's unilateral option to extend performance for an additional period up to six months under FAR 52.217-8, during which the pricing and terms of the period in which the option was exercised would apply. The Government cannot predict if or when the option may be exercised. Because any exercise of the Government's option extends the pricing and terms of the period in which the option was exercised, the Government expressly and affirmatively evaluates pricing for the option to extend under 52.217-8 co-extensive with the Government's price evaluation for each of the base and option periods of this award. Because pricing for each period subject to possible extension under the 52.217-8 has been evaluated, pricing for any possible future use of that option to extend has, likewise, been evaluated and would apply in strict accordance with this evaluation in the event of the Government’s exercise of the option to extend services. (End of Provision)

Submission Requirements: Responses must include sufficient information to demonstrate the respondent’s capability to provide the required product or service. Price quotations shall include, at a minimum: unit price, list price, shipping and handling costs, delivery timeframe after award, delivery terms, prompt payment discount terms, F.O.B. point (destination or origin), product or catalog numbers, product descriptions, and any other relevant information.

Evaluation factors may include, but are not limited to: equipment capability, equipment warranty and maintenance coverage, delivery, past performance, technical capability, special features, trade-in considerations, expected lifecycle, warranty, maintenance availability, and environmental or energy efficiency considerations.

Respondents claiming to be manufacturers or authorized resellers of a specified brand-name product must provide:

(a) Product, catalog, model, and/or part number(s);

(b) Product description;

(c) Documentation demonstrating that the offered item meets all required salient characteristics;

(d) Quantity;

(e) Estimated price or cost;

(f) Shipping, handling, and/or installation charges; and

(g) Delivery timeframe after receipt of order.

Responses must also include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by September 21, 2026 and must reference solicitation number 75N98026Q01180-04776. Responses may be submitted electronically to Luz.Casey@nih.gov.

Contact Information:

Contract Specialist/Program Specialist: Luz Casey Email: Luz.Casey@nih.gov image1.png