CDC-RFA-DP16-1604 Amendment 1.pdf

Centers for Disease Control and Prevention

National Center for Chronic Disease Prevention and Health Promotion

Supporting and Maintaining the Surveillance System for Chronic Kidney Disease in the United States

CDC-RFA-DP16-1604

Application Due Date: 02/29/2016

Supporting and Maintaining the Surveillance System for Chronic Kidney Disease in the United States

CDC-RFA-DP16-1604

TABLE OF CONTENTS

Part I. Overview Information Federal Agency NameA.

Funding Opportunity TitleB.

Announcement TypeC.

Agency Funding Opportunity NumberD.

Catalog of Federal Domestic Assistance (CFDA) NumberE.

Dates F.

Executive Summary G.

Part II. Full Text Funding Opportunity Description A.

Award Information B.

Eligibility Information C.

Required Registrations D.

Review and Selection Process E.

Award Administration Information F.

Agency Contacts G.

Other Information H.

Glossary I.

Part I. Overview Information Applicants must go to the synopsis page of this announcement at www.grants.gov and click on the "Send Me Change Notifications Emails" link to ensure they receive notifications of any changes to CDC-RFA-DP16-1604. Applicants also must provide an e-mail address to www.grants.gov to receive notifications of changes.

A. Federal Agency Name:

Centers for Disease Control and Prevention (CDC)

B. Funding Opportunity Title:

Supporting and Maintaining the Surveillance System for Chronic Kidney Disease in the United States

C. Announcement Type: New - Type 1

This announcement is only for non-research domestic activities supported by CDC. If research is proposed, the application will not be considered Research for this purpose is defined at http://www.cdc.gov/od/science/integrity/docs/cdc-policy-distinguishing-public-health-research-nonresearc h.pdf.

This funding opportunity announcement (FOA) solicits non-research cooperative agreement applications to build upon previous developmental work in chronic kidney disease (CKD) surveillance to continue developing, supporting, and improving the current CKD Surveillance System in the United States http://www.cdc.gov/ckd/surveillance.

D. Agency Funding Opportunity Number:

CDC-RFA-DP16-1604

E. Catalog of Federal Domestic Assistance (CFDA) Number:

93.833

F. Dates:

1. Due Date for Letter of Intent (LOI): 01/15/2016 Is a LOI: Recommended but not Required A letter of intent (LOI) is requested but optional. Submit the LOI by email or mail (i.e., sent by US mail or private carrier) directly to:

Nilka Ríos Burrows, MPH, MT (ASCP) Project Officer Department of Health and Human Services Centers for Disease Control and Prevention National Center for Chronic Disease Prevention and Health Promotion Division of Diabetes Translation 4770 Buford Highway NE, Mailstop F75 Telephone: 770-488-1057 Email: nrios@cdc.gov Although the LOI is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows CDC Program staff to estimate and plan the review of submitted applications.

2. Due Date for Applications: 02/29/2016, 11:59 p.m. U.S. Eastern Standard Time, at www.grants.gov.

3. Date for Informational Conference Call: N/A

G. Executive Summary:

1. Summary Paragraph:

This funding opportunity announcement (FOA) solicits non-research cooperative agreement applications for the following two components:

Component A: To build upon previous developmental work in chronic kidney disease (CKD) surveillance to continue developing, supporting, and improving the current CKD Surveillance System in the United States http://www.cdc.gov/ckd/surveillance. This is a comprehensive surveillance system that resides in a website application and integrates existing CKD data from multiple US data sources such as national surveys and registries, health care administrative data, and large cohort studies. This surveillance system will enable the government and others to monitor trends in the burden of CKD and its risk factors over time and also monitor trends in Healthy People 2020 objectives related to CKD prevention and control.

Component B: To provide computer support and technical management, update, and enhance the currently functional and interactive website application of the CKD Surveillance System http://www.cdc.gov/ckd/surveillance. The website will be used to 1) document the burden of CKD and its risk factors in the United States population over time, 2) disseminate timely and accurate CKD surveillance data and trends, 3) track the progress of efforts to achieve Healthy People 2020 objectives to prevent, detect, and manage CKD, and 4) provide the means for evaluating, monitoring, and implementing quality improvement efforts by both federal and nonfederal agencies.

Applicants are required to submit one application for both Component A and Component B of this FOA. Up to two applicants will receive the award for Component A, and one of the recipients of Component A will also be funded for Component B. An application requesting funds for https://foa.grantsolutions.gov/announcementmodule/www.grants.gov https://foa.grantsolutions.gov/announcementmodule/www.grants.gov http://www.cdc.gov/od/science/integrity/docs/cdc-policy-distinguishing-public-health-research-nonresearch.pdf http://www.cdc.gov/od/science/integrity/docs/cdc-policy-distinguishing-public-health-research-nonresearch.pdf http://www.cdc.gov/ckd/surveillance http://www.grants.gov http://www.cdc.gov/ckd/surveillance

Component A only or Component B only will not be considered.

a. Eligible Applicants: Open Competition

b. FOA Type: Cooperative Agreement

c. Approximate Number of Awards: 3

d. Total Project Period Funding: $6,000,000

e. Average One Year Award Amount: $600,000 Average annual funding for Component A is $500,000 each for two awardees, and average annual funding for Component B is $200,000 for one awardee. One of the recipients of the award for Component A will receive the award for Component B.

f. Number of Years of Award: 5

g. Estimated Award Date: 09/30/2016

h. Cost Sharing and / or Matching Requirements: N Cost sharing or matching funds are not required for this program. Although no statutory matching requirement for this FOA exists, leveraging other resources and related ongoing efforts to promote sustainability is strongly encouraged.

Part II. Full Text Executive Summary

This funding opportunity announcement (FOA) solicits non-research cooperative agreement applications for the following two components:

Component A: To build upon previous developmental work in chronic kidney disease (CKD) surveillance to continue developing, supporting, and improving the current CKD Surveillance System in the United States http://www.cdc.gov/ckd/surveillance. This is a comprehensive surveillance system that resides in a website application and integrates existing CKD data from multiple US data sources such as national surveys and registries, health care administrative data, and large cohort studies. This surveillance system will enable the government and others to monitor trends in the burden of CKD and its risk factors over time and also monitor trends in Healthy People 2020 objectives related to CKD prevention and control.

Component B: To provide computer support and technical management, update, and enhance the currently functional and interactive website application of the CKD Surveillance System http://www.cdc.gov/ckd/surveillance. The website will be used to 1) document the burden of CKD and its risk factors in the United States population over time, 2) disseminate timely and accurate CKD surveillance data and trends, 3) track the progress of efforts to achieve Healthy People 2020 objectives to prevent, detect, and manage CKD, and 4) provide the means for evaluating, monitoring, and implementing quality improvement efforts by both federal and nonfederal agencies.

Applicants are required to submit one application for both Component A and Component B of this FOA. Up to two applicants will receive the award for Component A, and one of the recipients of Component A will also be funded for Component B. An application requesting funds for Component A only or Component B only will not be considered.

A. Funding Opportunity Description

1. Background

a. Overview Kidney diseases are the ninth leading cause of death in the United States. More than 10% of US adults—more than 20 million people— may have CKD, and most of them are not aware of their condition. The range of CKD extends from microalbuminuria (the leakage of excess protein into the urine as a result of kidney damage) to end stage renal disease (ESRD) (that is, the final stage of CKD characterized by kidney failure and requiring dialysis or transplantation for survival). CKD is a serious and growing problem. The number of new cases of ESRD in the US population has more than doubled since 1990 and it is expected to continue to grow with the increasing prevalence of diabetes, a major risk factor that accounts for nearly half of all new cases of ESRD. However, preventing CKD and its complications is possible by managing risk factors and treating the disease to slow its progression and reduce the risk of complications.

In recognition of the growing problem of kidney disease, Congress passed legislation —the Labor, Health and Human Services, and Education (L/HHS/Ed) and Related Agencies Appropriation Bill, 2006 Conference Report —to develop capacity and infrastructure at CDC for a kidney disease surveillance, epidemiology, health economics, and health outcomes evaluation program. The program, known as CDC’s CKD Initiative, is designed to provide public health strategies for promoting kidney health. These strategies seek to prevent and control risk factors for CKD, raise awareness, promote early diagnosis, and improve outcomes and quality of life for those living with CKD. Current activities include surveillance and epidemiology, state-based demonstration projects, and health outcomes and economic studies in partnership with other government agencies, universities, and national organizations.

Staff from CDC’s CKD Initiative in the Division of Diabetes Translation (DDT), Epidemiology and Statistics Branch, in collaboration with partners, established and implemented the CKD Surveillance System http://www.cdc.gov/ckd/surveillance to keep track of CKD and its risk factors in the US population over time. This comprehensive system allows the federal government and others to document and monitor trends in the burden of CKD and its risk factors over time, track progress in preventing, detecting, and managing CKD and in achieving the Healthy People 2020 CKD objectives.

It also provides the means for evaluating, monitoring, and implementing programmatic and quality improvement efforts by both federal and nonfederal agencies.

http://www.cdc.gov/ckd/surveillance

1. Background

a. Overview Kidney diseases are the ninth leading cause of death in the United States. More than 10% of US adults—more than 20 million people— may have CKD, and most of them are not aware of their condition. The range of CKD extends from microalbuminuria (the leakage of excess protein into the urine as a result of kidney damage) to end stage renal disease (ESRD) (that is, the final stage of CKD characterized by kidney failure and requiring dialysis or transplantation for survival). CKD is a serious and growing problem. The number of new cases of ESRD in the US population has more than doubled since 1990 and it is expected to continue to grow with the increasing prevalence of diabetes, a major risk factor that accounts for nearly half of all new cases of ESRD. However, preventing CKD and its complications is possible by managing risk factors and treating the disease to slow its progression and reduce the risk of complications.

In recognition of the growing problem of kidney disease, Congress passed legislation —the Labor, Health and Human Services, and Education (L/HHS/Ed) and Related Agencies Appropriation Bill, 2006 Conference Report —to develop capacity and infrastructure at CDC for a kidney disease surveillance, epidemiology, health economics, and health outcomes evaluation program. The program, known as CDC’s CKD Initiative, is designed to provide public health strategies for promoting kidney health. These strategies seek to prevent and control risk factors for CKD, raise awareness, promote early diagnosis, and improve outcomes and quality of life for those living with CKD. Current activities include surveillance and epidemiology, state-based demonstration projects, and health outcomes and economic studies in partnership with other government agencies, universities, and national organizations.

Staff from CDC’s CKD Initiative in the Division of Diabetes Translation (DDT), Epidemiology and Statistics Branch, in collaboration with partners, established and implemented the CKD Surveillance System http://www.cdc.gov/ckd/surveillance to keep track of CKD and its risk factors in the US population over time. This comprehensive system allows the federal government and others to document and monitor trends in the burden of CKD and its risk factors over time, track progress in preventing, detecting, and managing CKD and in achieving the Healthy People 2020 CKD objectives.

It also provides the means for evaluating, monitoring, and implementing programmatic and quality improvement efforts by both federal and nonfederal agencies.

This FOA will build upon the previous developmental work in CKD surveillance to continue developing, supporting, and improving the CKD Surveillance System with CKD indicators and up-to-date data and trends, and to assist CDC, prevention researchers, policy makers, medical practitioners, and states to develop and evaluate programs and policies that better prevent, detect, and manage CKD.

In particular, this FOA solicits non-research cooperative agreement applications for the following two components:

Developing, supporting, and improving the CKD Surveillance System in the United States (Component A), and Maintaining, updating, and enhancing the currently functional and interactive CKD Surveillance System website application (Component B).

b. Statutory Authorities

Section 317(k)(2) of the Public Health Service Act (PHS Act), 42 U.S.C. 247b(k)(2), Section 301(a) of the PHS Act, 42 U.S.C. 241(a).

c. Healthy People 2020 This funding opportunity aligns with the Healthy People 2020 focus area of CKD and its risk factors, complications, disability, and mortality.

Additional information is available at http://www.healthypeople.gov/2020/topics-objectives/topic/chronic-kidney-disease.

d. Other National Public Health Priorities and Strategies The purpose and outcomes of the FOA support and align with the following strategic goals and core functions of CDC's National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP) and of CDC's Division of Diabetes Translation (DDT):

NCCDPHP/DDT Government Performance Results Act (GPRA) goals and objectives:

Strategic Goal 2: Advance Scientific Knowledge and Innovation Objective E: Improve laboratory, surveillance, and epidemiology capacity

Strategic Goal 3: Advance the Health, Safety, and Well-Being of the American People Objective D: Promote prevention and wellness across the life span

DDT core function, strategic goal, and priority:

Core function: Surveillance

Strategic Goal 2: Prevent complications, disabilities, and burden associated with diabetes

Priority C: Conduct surveillance and applied research to identify and prioritize effective approaches and targeted sub-populations for diabetes prevention and control.

More information about this and other performance measures can be found in the CDC fiscal year (FY) 2012 Online Performance Appendix at the following Internet address: http://intranet.cdc.gov/od/ppeo/docs/FinalOPA_CDC_FY2012.pdf

e. Relevant Work Staff from CDC’s CKD Initiative in the Division of Diabetes Translation, Epidemiology and Statistics Branch, in collaboration with partners, established and implemented the CKD Surveillance System in the United States which currently resides in a website application http://www.cdc.gov /ckd/surveillance.

Highlights of the CKD Surveillance System website application include:

Interactive website that allows the user to view surveillance data on CKD prevalence and incidence, awareness, and healthcare consequences, among other topics, and by different characteristics (for example, by age and by sex) for which data are available.

Data from different sources, including national surveys (e.g., National Health and Nutrition Examination Survey), electronic health record systems (e.g., US Department of Veterans Affairs), claims data (e.g., Centers for Medicare & Medicaid Services and US Renal Data System), and longitudinal studies (e.g., Atherosclerosis Risk in Communities and Renal Reasons for Geographic and Racial Differences in Stroke).

Special section to monitor progress in achieving Healthy People 2020CKD objectives. This system provides data that can be used to monitor progress on 10 of the 14 CKD and kidney failure objectives in Healthy People 2020.

Special sections on the burden of risk factors for CKD, including diabetes, obesity, hypertension, cardiovascular disease, smoking, and acute kidney injury, and on special populations, including children and adolescents with kidney disease.

Ability to download the graphs and data tables.

2. CDC Project Description

a. Approach

Bold indicates project period outcome.

CDC’s CKD Initiative provides public health strategies for promoting kidney health in collaboration with many partners. These strategies seek to http://www.healthypeople.gov/2020/topics-objectives/topic/chronic-kidney-disease http://intranet.cdc.gov/od/ppeo/docs/FinalOPA_CDC_FY2012.pdf http://intranet.cdc.gov/od/ppeo/docs/FinalOPA_CDC_FY2012.pdf

This FOA will build upon the previous developmental work in CKD surveillance to continue developing, supporting, and improving the CKD Surveillance System with CKD indicators and up-to-date data and trends, and to assist CDC, prevention researchers, policy makers, medical practitioners, and states to develop and evaluate programs and policies that better prevent, detect, and manage CKD.

In particular, this FOA solicits non-research cooperative agreement applications for the following two components:

Developing, supporting, and improving the CKD Surveillance System in the United States (Component A), and Maintaining, updating, and enhancing the currently functional and interactive CKD Surveillance System website application (Component B).

b. Statutory Authorities

Section 317(k)(2) of the Public Health Service Act (PHS Act), 42 U.S.C. 247b(k)(2), Section 301(a) of the PHS Act, 42 U.S.C. 241(a).

c. Healthy People 2020 This funding opportunity aligns with the Healthy People 2020 focus area of CKD and its risk factors, complications, disability, and mortality.

Additional information is available at http://www.healthypeople.gov/2020/topics-objectives/topic/chronic-kidney-disease.

d. Other National Public Health Priorities and Strategies The purpose and outcomes of the FOA support and align with the following strategic goals and core functions of CDC's National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP) and of CDC's Division of Diabetes Translation (DDT):

NCCDPHP/DDT Government Performance Results Act (GPRA) goals and objectives:

Strategic Goal 2: Advance Scientific Knowledge and Innovation Objective E: Improve laboratory, surveillance, and epidemiology capacity

Strategic Goal 3: Advance the Health, Safety, and Well-Being of the American People Objective D: Promote prevention and wellness across the life span

DDT core function, strategic goal, and priority:

Core function: Surveillance

Strategic Goal 2: Prevent complications, disabilities, and burden associated with diabetes

Priority C: Conduct surveillance and applied research to identify and prioritize effective approaches and targeted sub-populations for diabetes prevention and control.

More information about this and other performance measures can be found in the CDC fiscal year (FY) 2012 Online Performance Appendix at the following Internet address: http://intranet.cdc.gov/od/ppeo/docs/FinalOPA_CDC_FY2012.pdf

e. Relevant Work Staff from CDC’s CKD Initiative in the Division of Diabetes Translation, Epidemiology and Statistics Branch, in collaboration with partners, established and implemented the CKD Surveillance System in the United States which currently resides in a website application http://www.cdc.gov /ckd/surveillance.

Highlights of the CKD Surveillance System website application include:

Interactive website that allows the user to view surveillance data on CKD prevalence and incidence, awareness, and healthcare consequences, among other topics, and by different characteristics (for example, by age and by sex) for which data are available.

Data from different sources, including national surveys (e.g., National Health and Nutrition Examination Survey), electronic health record systems (e.g., US Department of Veterans Affairs), claims data (e.g., Centers for Medicare & Medicaid Services and US Renal Data System), and longitudinal studies (e.g., Atherosclerosis Risk in Communities and Renal Reasons for Geographic and Racial Differences in Stroke).

Special section to monitor progress in achieving Healthy People 2020CKD objectives. This system provides data that can be used to monitor progress on 10 of the 14 CKD and kidney failure objectives in Healthy People 2020.

Special sections on the burden of risk factors for CKD, including diabetes, obesity, hypertension, cardiovascular disease, smoking, and acute kidney injury, and on special populations, including children and adolescents with kidney disease.

Ability to download the graphs and data tables.

2. CDC Project Description

a. Approach

Bold indicates project period outcome.

CDC’s CKD Initiative provides public health strategies for promoting kidney health in collaboration with many partners. These strategies seek to http://www.healthypeople.gov/2020/topics-objectives/topic/chronic-kidney-disease http://intranet.cdc.gov/od/ppeo/docs/FinalOPA_CDC_FY2012.pdf http://intranet.cdc.gov/od/ppeo/docs/FinalOPA_CDC_FY2012.pdf

CDC’s CKD Initiative provides public health strategies for promoting kidney health in collaboration with many partners. These strategies seek to prevent and control risk factors for CKD, raise awareness, promote early diagnosis, and improve outcomes and quality of life for those living with CKD. This FOA will build upon the previous developmental work in CKD surveillance to continue supporting, updating, and growing the current CKD Surveillance System in the United States http://www.cdc.gov/ckd/surveillance. Strategies and activities to build upon this previous work are described in the Strategies and Activities section below. The CKD Surveillance System will enable the government and others to monitor trends in the burden of CKD and its risk factors over time as well as to monitor and evaluate trends towards achieving the Healthy People 2020 CKD objectives. It will also assist CDC, prevention researchers, policy makers, medical practitioners, and states to develop and evaluate programs and policies that better prevent, detect, and manage CKD.

In addition to developing, supporting, and improving the CKD Surveillance System (Component A), one of the recipients of this award will also be funded to provide computer support and technical management, update, and enhance the currently functional and interactive website application of the CKD Surveillance System http://www.cdc.gov/ckd/surveillance (Component B). This website is used to 1) document the burden of CKD and its risk factors in the United States population over time, 2) disseminate timely and accurate CKD surveillance data and trends, 3) track the progress of efforts to achieve Healthy People 2020 objectives to prevent, detect, and manage CKD, and 4) provide the means for evaluating, monitoring, and implementing quality improvement efforts by both federal and nonfederal agencies. The website application resides in the NCCDPHP server at CDC, conforms to CDC information technology (IT) requirements, and is accessible to both internal and external CDC users.

Logic Model with strategies, activities, and outcomes to accomplish during the project period:

Strategies and Activities: Component A Short-term Outcomes Long-term Outcomes

SUPPORT and EVALUATION: Support, update, and grow the existing surveillance system for CKD with up-to-date data and trends.

Collaborate with programs internal and external to CDC to establish data sharing agreements for access to data relevant to CKD surveillance.

Identify, assess, and add CKD indicators to the surveillance system as data sources allow and as the science evolves and emerges.

Focus surveillance data efforts on social determinants of health and populations that are disproportionately affected by CKD and on sources that provide CKD estimates at various geographic levels.

Develop an evaluation plan to identify gaps in surveillance data and future needs, and a plan to integrate the CKD surveillance system with other established surveillance systems.

Improved breadth and scope of CKD surveillance data in the United States.

Established programmatic and quality improvement efforts by both federal and nonfederal agencies.

System is the largest comprehensive collection of CKD data in the United States.

Continued support of the CDC’s CKD Surveillance Project by internal and external stakeholders.

DISSEMINATION: Publish and disseminate CKD surveillance findings and develop practical tools (e.g., risk calculators, screening tools, Web applications) to improve identification of the population at risk for CKD.

HEALTHY PEOPLE: Provide data management, analyses, and reports to monitor progress in achieving the Healthy People 2020 CKD objectives.

SUSTAINABILITY: Provide written documentation of data sources, data sets, and data analyses to allow CDC to maintain and modify the Web application in the future.

Increased visibility of the CKD Surveillance System website by internal and external stakeholders.

Raised awareness among health providers of CKD and its risk factors, and promotion of early diagnosis and treatment.

Documented progress on Healthy People 2020 CKD objectives.

Influence patient care recommendations.

Improve identification of the population at risk and improved care and outcomes for people living with

CKD.

Informed Healthy People 2030 CKD objectives.

Strategies and Activities: Component B Short-term Outcomes Long-term Outcomes

SUPPORT: Provide computer support and technical management of the CKD Surveillance System website application.

Work in collaboration with the CDC IT program in performing CKD Web updates and in conforming to CDC IT requirements.

Timely and accurate dissemination of CKD surveillance data and trends for public health action.

Internal and external stakeholders view site as the reliable and first-rate resource to monitor CKD burden and CKD prevention and control efforts in the United States.

EVALUATION: Enhance the usability of the website application and the user experience, and provide feedback and evaluation of the website application.

Stay up-to-date with the latest developments in computer software and IT.

SUSTAINABILITY: Provide written user documentation of the system to allow CDC to maintain and modify the Web application in the future.

Improved user experience of the CKD Surveillance System website application.

i. Purpose

CDC’s CKD Initiative provides public health strategies for promoting kidney health in collaboration with many partners. These strategies seek to prevent and control risk factors for CKD, raise awareness, promote early diagnosis, and improve outcomes and quality of life for those living with CKD. This FOA will build upon the previous developmental work in CKD surveillance to continue supporting, updating, and growing the current CKD Surveillance System in the United States http://www.cdc.gov/ckd/surveillance. Strategies and activities to build upon this previous work are described in the Strategies and Activities section below. The CKD Surveillance System will enable the government and others to monitor trends in the burden of CKD and its risk factors over time as well as to monitor and evaluate trends towards achieving the Healthy People 2020 CKD objectives. It will also assist CDC, prevention researchers, policy makers, medical practitioners, and states to develop and evaluate programs and policies that better prevent, detect, and manage CKD.

In addition to developing, supporting, and improving the CKD Surveillance System (Component A), one of the recipients of this award will also be funded to provide computer support and technical management, update, and enhance the currently functional and interactive website application of the CKD Surveillance System http://www.cdc.gov/ckd/surveillance (Component B). This website is used to 1) document the burden of CKD and its risk factors in the United States population over time, 2) disseminate timely and accurate CKD surveillance data and trends, 3) track the progress of efforts to achieve Healthy People 2020 objectives to prevent, detect, and manage CKD, and 4) provide the means for evaluating, monitoring, and implementing quality improvement efforts by both federal and nonfederal agencies. The website application resides in the NCCDPHP server at CDC, conforms to CDC information technology (IT) requirements, and is accessible to both internal and external CDC users.

Logic Model with strategies, activities, and outcomes to accomplish during the project period:

i. Purpose

This FOA will build upon the previous developmental work in CKD surveillance to continue developing, supporting, and improving the CKD Surveillance System with CKD indicators and up-to-date data and trends, and to assist CDC, prevention researchers, policy makers, medical practitioners, and states to develop and evaluate programs and policies that better prevent, detect, and manage CKD.

ii. Outcomes Outcomes to accomplish during the project period:

Short-term Outcomes:

Improved breadth and scope of CKD surveillance data in the United States.

Established programmatic and quality improvement efforts by both federal and nonfederal agencies.

Increased visibility of the CKD Surveillance System website by internal and external stakeholders.

Heightened awareness among health providers of CKD and its risk factors, and promotion of early diagnosis and treatment.

Documented progress on Healthy People 2020 objectives related to CKD prevention and control.

Timely and accurate dissemination of CKD surveillance data and trends for public health action.

Improved user experience of the CKD Surveillance System website application.

Long-term Outcomes:

System is the the largest comprehensive collection of CKD data in the United States.

Continued support of the CDC’s CKD Surveillance Project by internal and external stakeholders.

Influence patient care recommendations, informed by data from the CKD Surveillance System.

Improve identification and targeting of the population at high risk for CKD for preventive, clinical, and public health interventions, and improved care, outcomes, and quality of life for people living with CKD.

Appropriate and relevant Healthy People 2030 CKD objectives, informed by data from the CKD Surveillance System.

Internal and external stakeholders view the site as the reliable and first-rate resource to monitor CKD burden and CKD prevention and control efforts in the United States.

iii. Strategies and Activities Recipient Activities (Component A)

Establish goals and objectives that are realistic, measurable, and time-oriented for the project.

Support, update, and expand, in collaboration with the recipient of Component B, the existing CKD Surveillance System website with up-to-date data and trends for CKD, its risk factors, health consequences, and processes of care.

Collaborate with CDC programs (e.g., CDC’s National Center for Health Statistics) and with organizations external to CDC, such as other federal or state government agencies, academic institutions, and non-profit and international organizations.

Establish data sharing agreements with appropriate federal and public and private partners for access to data relevant to CKD surveillance.Identify and rigorously assess CKD indicators as data sources allow and as the science evolves and emerges.

List, update, and add to the existing CKD Surveillance System possible measures and indicators of CKD burden (e.g., incidence, awareness, prevalence, risk factors, consequences, and costs), social determinants of health, geographic indicators, and CKD in special and vulnerable populations.

Focus surveillance data efforts on target populations that are disproportionately affected by CKD and identify surveillance and information needs to help address disparities in CKD.

Publish and disseminate surveillance findings on burden and trends of CKD in the United States, risk factors, preventive practices, social determinants of health, and disparities in the population with CKD.

Develop practical tools such as risk calculators, screening tools, or Web applications to improve identification and targeting of the population at high risk for CKD for preventive, clinical, and public health interventions.

Develop an evaluation plan of CKD surveillance content to identify gaps in surveillance data and future information needs.

Develop and implement a comprehensive plan to integrate data sources into the existing functional CKD surveillance system and to integrate this CKD surveillance system with other established surveillance systems.

Provide data management, analyses, and reports to monitor progress in achieving the Healthy People 2020 CKD objectives and inform the process in developing Healthy People 2030 CKD objectives.

Provide written documentation of data sources, data sets, and data analyses (e.g., coding and computer programs) to allow CDC to maintain the surveillance system in the future.

Ensure adequate staffing and oversight in support of the project.

Recipient Activities (Component B) In collaboration with the recipient of Component A:

Provide computer support and technical management of the CKD Surveillance System website application http://www.cdc.gov/ckd/surveillance. Technical management includes developing plans for programming and creating databases and Web systems, coordinating system designs including interfaces, business rules, and security models, and testing and deployment.

Work in collaboration with the CDC IT program in performing uploads of CKD surveillance data and Web updates.

Conform to CDC IT requirements, Web templates (including responsive design), and security clearances. All applications will exist within NCCDPHP- and CDC-supported Internet infrastructure and must conform to all performance, reliability, stability, and security standards.

Enhance the usability of the website application and the user experience.

Provide feedback and evaluation (e.g., detailed requirements analyses, website analytics, usability testing) of the website application to ensure that program and user needs are identified and met through the application.

Stay up-to-date with the latest developments in computer software and IT.

Provide written user documentation of the system (e.g., project requirements, system overview and architecture, database specifications, programs and system components) to allow CDC to maintain and modify the Web application in the future.

This FOA will build upon the previous developmental work in CKD surveillance to continue developing, supporting, and improving the CKD Surveillance System with CKD indicators and up-to-date data and trends, and to assist CDC, prevention researchers, policy makers, medical practitioners, and states to develop and evaluate programs and policies that better prevent, detect, and manage CKD.

ii. Outcomes Outcomes to accomplish during the project period:

Short-term Outcomes:

Improved breadth and scope of CKD surveillance data in the United States.

Established programmatic and quality improvement efforts by both federal and nonfederal agencies.

Increased visibility of the CKD Surveillance System website by internal and external stakeholders.

Heightened awareness among health providers of CKD and its risk factors, and promotion of early diagnosis and treatment.

Documented progress on Healthy People 2020 objectives related to CKD prevention and control.

Timely and accurate dissemination of CKD surveillance data and trends for public health action.

Improved user experience of the CKD Surveillance System website application.

Long-term Outcomes:

System is the the largest comprehensive collection of CKD data in the United States.

Continued support of the CDC’s CKD Surveillance Project by internal and external stakeholders.

Influence patient care recommendations, informed by data from the CKD Surveillance System.

Improve identification and targeting of the population at high risk for CKD for preventive, clinical, and public health interventions, and improved care, outcomes, and quality of life for people living with CKD.

Appropriate and relevant Healthy People 2030 CKD objectives, informed by data from the CKD Surveillance System.

Internal and external stakeholders view the site as the reliable and first-rate resource to monitor CKD burden and CKD prevention and control

iii. Strategies and Activities Recipient Activities (Component A)

Establish goals and objectives that are realistic, measurable, and time-oriented for the project.

Support, update, and expand, in collaboration with the recipient of Component B, the existing CKD Surveillance System website with up-to-date data and trends for CKD, its risk factors, health consequences, and processes of care.

Collaborate with CDC programs (e.g., CDC’s National Center for Health Statistics) and with organizations external to CDC, such as other federal or state government agencies, academic institutions, and non-profit and international organizations.

Establish data sharing agreements with appropriate federal and public and private partners for access to data relevant to CKD surveillance.Identify and rigorously assess CKD indicators as data sources allow and as the science evolves and emerges.

List, update, and add to the existing CKD Surveillance System possible measures and indicators of CKD burden (e.g., incidence, awareness, prevalence, risk factors, consequences, and costs), social determinants of health, geographic indicators, and CKD in special and vulnerable populations.

Focus surveillance data efforts on target populations that are disproportionately affected by CKD and identify surveillance and information needs to help address disparities in CKD.

Publish and disseminate surveillance findings on burden and trends of CKD in the United States, risk factors, preventive practices, social determinants of health, and disparities in the population with CKD.

Develop practical tools such as risk calculators, screening tools, or Web applications to improve identification and targeting of the population at high risk for CKD for preventive, clinical, and public health interventions.

Develop an evaluation plan of CKD surveillance content to identify gaps in surveillance data and future information needs.

Develop and implement a comprehensive plan to integrate data sources into the existing functional CKD surveillance system and to integrate this CKD surveillance system with other established surveillance systems.

Provide data management, analyses, and reports to monitor progress in achieving the Healthy People 2020 CKD objectives and inform the process in developing Healthy People 2030 CKD objectives.

Provide written documentation of data sources, data sets, and data analyses (e.g., coding and computer programs) to allow CDC to maintain the surveillance system in the future.

Ensure adequate staffing and oversight in support of the project.

Recipient Activities (Component B) In collaboration with the recipient of Component A:

Provide computer support and technical management of the CKD Surveillance System website application http://www.cdc.gov/ckd/surveillance. Technical management includes developing plans for programming and creating databases and Web systems, coordinating system designs including interfaces, business rules, and security models, and testing and deployment.

Work in collaboration with the CDC IT program in performing uploads of CKD surveillance data and Web updates.

Conform to CDC IT requirements, Web templates (including responsive design), and security clearances. All applications will exist within NCCDPHP- and CDC-supported Internet infrastructure and must conform to all performance, reliability, stability, and security standards.

Enhance the usability of the website application and the user experience.

Provide feedback and evaluation (e.g., detailed requirements analyses, website analytics, usability testing) of the website application to ensure that program and user needs are identified and met through the application.

Stay up-to-date with the latest developments in computer software and IT.

Provide written user documentation of the system (e.g., project requirements, system overview and architecture, database specifications, programs and system components) to allow CDC to maintain and modify the Web application in the future.

1.Collaborations The applicant needs to provide evidence of demonstrated partnerships, access to data and data use agreements for the proposed or existing collaborations to address the goals, objectives, and intent of the FOA.

a. With other CDC programs and CDC-funded organizations:

The applicant needs to collaborate with CDC programs (e.g., CDC’s National Center for Health Statistics) for access to data relevant to CKD surveillance.

b. With organizations not funded by CDC:

The applicant needs to 1) collaborate with organizations external to CDC, such as other federal or state government agencies, academic institutions, and non-profit and international organizations for access to data relevant to CKD surveillance, 2) establish data sharing agreements with appropriate federal and public and private partners for data access, and 3) provide evidence of demonstrated partnerships, and data access and data use agreements for the proposed or existing collaborations to address the goals, objectives, and intent of the FOA.

Applicants are advised that any activities involving information collections (i.e., surveys, questionnaires, applications, audits, data requests, reporting, recordkeeping and disclosure requirements, etc.) from 10 or more non-Federal entities, including State and local governmental agencies, are subject to the conditions of the Paperwork Reduction Act of 1995 (PRA). Under the PRA, a Federal agency sponsoring a standardized data collection or directly obtaining standardized or substantially similar information from ten or more persons or entities (other than Federal employees within the scope of their employment) in any 12-month period must obtain advance written approval from the Office of Management and Budget (OMB).” Regardless of form or format (oral, written, or electronically transmitted), responses of opinion or fact requested or required by or for CDC, except those specifically exempted or excluded, are subject to the provisions of the PRA and its implementing regulation, 5 CFR 1320 (Controlling Paperwork Burdens on the Public).”

2. Target Populations The applicant needs to demonstrate a wide reach for surveillance data among minority, vulnerable, and at-risk populations for CKD or other chronic diseases, including tribal populations, veteran populations, and medically underserved populations.

1) Provide evidence of prior work in this area.

2) Demonstrate established collaborations with institutions (e.g., Indian Health Service, Department of Veterans Affairs, federally-qualified health centers) that serve populations that are disproportionately affected by CKD or other chronic diseases.

3) Develop a plan for a) obtaining access to CKD-relevant surveillance data from such institutions, b) incorporating such data into the CKD Surveillance System, and c) identifying surveillance and information needs to help address population disparities in CKD.

a. Inclusion

iv. Funding Strategy (for multi-component FOAs only) Applicants are required to apply for both Component A and Component B of this FOA. Up to two applicants will receive the award for Component A.

Component A: To build upon previous developmental work in chronic kidney disease (CKD) surveillance to continue developing, supporting, and improving the current CKD Surveillance System in the United States http://www.cdc.gov/ckd/surveillance.

One of the recipients of Component A will also be funded for Component B.

Component B: To provide computer support and technical management, update, and enhance the currently functional and interactive website application of the CKD Surveillance System http://www.cdc.gov/ckd/surveillance.

Average annual funding for Component A is $500,000, and average annual funding for Component B is $200,000.

An application addressing Component A only or Component B only will not be considered.

b. Evaluation and Performance Measurement

i. CDC Evaluation and Performance Measurement Strategy

Strategies and Activities: Component A Performance Measure

SUPPORT and EVALUATION: Support, update, and expand the existing surveillance system for CKD with up-to-date data and trends.

Collaborate with programs internal and external to CDC to establish data sharing agreements for access to data relevant to CKD surveillance.

Identify, assess, and add CKD indicators to the surveillance system as data sources allow and as the science evolves and emerges.

Focus surveillance data efforts on social determinants of health and populations that are disproportionately affected by CKD and on sources that provide CKD estimates at various geographic levels.

Develop an evaluation plan to identify gaps in surveillance data and future needs, and a plan to integrate the CKD surveillance system with other established surveillance systems.

DISSEMINATION: Publish and disseminate CKD surveillance findings and develop practical tools (e.g., risk calculators, screening tools, Web applications) to improve identification of the population at risk for CKD.

SUPPORT AND EVALUATION:

Preserve the viable and functional CKD Surveillance System website http://www.cdc.gov /ckd/surveillance.

Document an increase in the number of CKD surveillance topics and indicators to show the expansion and growth of the CKD Surveillance System website.

Provide feedback on CKD surveillance content, gaps in surveillance data, and future data and information needs.

DISSEMINATION: Document an increase in the number of publications to disseminate the CKD surveillance findings.

http://www.cdc.gov/ckd/surveillance http://www.cdc.gov/ckd/surveillance

1.Collaborations The applicant needs to provide evidence of demonstrated partnerships, access to data and data use agreements for the proposed or existing collaborations to address the goals, objectives, and intent of the FOA.

a. With other CDC programs and CDC-funded organizations:

The applicant needs to collaborate with CDC programs (e.g., CDC’s National Center for Health Statistics) for access to data relevant to CKD surveillance.

b. With organizations not funded by CDC:

The applicant needs to 1) collaborate with organizations external to CDC, such as other federal or state government agencies, academic institutions, and non-profit and international organizations for access to data relevant to CKD surveillance, 2) establish data sharing agreements with appropriate federal and public and private partners for data access, and 3) provide evidence of demonstrated partnerships, and data access and data use agreements for the proposed or existing collaborations to address the goals, objectives, and intent of the FOA.

Applicants are advised that any activities involving information collections (i.e., surveys, questionnaires, applications, audits, data requests, reporting, recordkeeping and disclosure requirements, etc.) from 10 or more non-Federal entities, including State and local governmental agencies, are subject to the conditions of the Paperwork Reduction Act of 1995 (PRA). Under the PRA, a Federal agency sponsoring a standardized data collection or directly obtaining standardized or substantially similar information from ten or more persons or entities (other than Federal employees within the scope of their employment) in any 12-month period must obtain advance written approval from the Office of Management and Budget (OMB).” Regardless of form or format (oral, written, or electronically transmitted), responses of opinion or fact requested or required by or for CDC, except those specifically exempted or excluded, are subject to the provisions of the PRA and its implementing regulation, 5 CFR 1320 (Controlling Paperwork Burdens on the Public).”

2. Target Populations The applicant needs to demonstrate a wide reach for surveillance data among minority, vulnerable, and at-risk populations for CKD or other chronic diseases, including tribal populations, veteran populations, and medically underserved populations.

1) Provide evidence of prior work in this area.

2) Demonstrate established collaborations with institutions (e.g., Indian Health Service, Department of Veterans Affairs, federally-qualified health centers) that serve populations that are disproportionately affected by CKD or other chronic diseases.

3) Develop a plan for a) obtaining access to CKD-relevant surveillance data from such institutions, b) incorporating such data into the CKD Surveillance System, and c) identifying surveillance and information needs to help address population disparities in CKD.

a. Inclusion

iv. Funding Strategy (for multi-component FOAs only) Applicants are required to apply for both Component A and Component B of this FOA. Up to two applicants will receive the award for Component A.

Component A: To build upon previous developmental work in chronic kidney disease…