cdc-rfa-dd10-1014 revised final 04 7 10.doc

Amendment to Section III Award Information and Requirements: Average Award

U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention (CDC)

National Charcot-Marie-Tooth Resource Center

I. AUTHORIZATION AND INTENT

Announcement Type: New – Type 1

Funding Opportunity Number: CDC-RFA-DD10-1014 Catalog of Federal Domestic Assistance Number: 93.184 Key Dates:

Application Deadline Date: May 14, 2010, on Grants.gov, 11:59pm Eastern Standard Time Authority:

This program is authorized under Sections 301 and 317C of the Public Health Service Act, (42 U.S.C., Sections 241, 243, and 247b-4), as amended.

Background:

Charcot-Marie-Tooth (CMT) Hereditary Neuropathy is a group of genetic disorders characterized by progressive distal motor and sensory neuropathy. Clinical features manifest between the first and third decades of life and include distal muscle weakness and wasting, mild to moderate sensory loss, depressed tendon reflexes, high-arched feet (pes cavus), and hip dysplasia. Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neurological disorders, affecting approximately 1 in 2,500 people in the United States (NIH, National Institute of Neurological Disorders and Stroke, 2009).

Although there is no cure for CMT, most affected individuals have a normal lifespan.

The gene mutations in CMT diseases are usually inherited. There are many forms of CMT disease, including CMT1, CMT2, CMT3, CMT4, and CMTX. Although different proteins are abnormal in these different forms of CMT disease, all of the mutations affect the normal function of the peripheral nerves. Consequently, these nerves slowly degenerate and lose the ability to communicate with their distant targets. The degeneration of motor nerves results in muscle weakness and atrophy in the extremities (arms, legs, hands, or feet). In some cases the degeneration of sensory nerves results in a reduced ability to feel heat, cold, and pain.

The severity of symptoms is variable in different CMT patients and even among family members with the disease. Individuals who have CMT and families affected by CMT may experience diagnostic delays and difficulties finding appropriate medical and social services. Resources are needed to increase knowledge and awareness of CMT for individuals and families affected by CMT, health care providers, and allied health care providers to improve health outcomes and promote well-being for people affected by this disease.

Purpose:

The purpose of the program is to establish a National Charcot-Marie-Tooth (CMT) Resource Center that will promote collaborative relationships between individuals who have CMT and their health care providers through education, training, and dissemination of information to promote accurate diagnosis, optimal treatment, and well-being for individuals who have CMT. The CMT Resource Center will provide resource materials online and in print to increase access to accurate and scientifically valid information on the etiology, diagnosis, and treatment of Charcot-Marie-Tooth (CMT), as well as links to useful resources for individuals and families affected by CMT and health care providers. The CMT Resource Center will expand the reach of disseminated information through collaborations with other organizations that target the national community of persons with CMT and their families, caregivers, and the health care professionals who manage and coordinate care.

This program addresses the “Healthy People 2010” focus area 6: Promote the health of people with disabilities, prevent secondary conditions, and eliminate disparities between people with and without disabilities in the U.S. population. Measurable outcomes of the program will be in alignment with one (or more) of the following performance goals for the National Center on Birth Defects and Developmental Disabilities:

· Improving the health and well-being of people with disabilities

· Helping children to develop and reach their full potential

· Promoting health and well-being among people of all ages with disabilities This announcement is only for non-research activities supported by CDC. If research is proposed, the application will not be reviewed. For the definition of research, please see the CDC Web site at the following Internet address: http://www.cdc.gov/od/science/regs/hrpp/researchDefinition.htm

II. PROGRAM IMPLEMENTATION

Recipient Activities:

1. Establish a National Charcot-Marie-Tooth (CMT) Resource Center that provides resource materials online and in print to increase access to accurate and scientifically valid information on the etiology, diagnosis, and treatment of CMT, as well as links to useful resources for individuals and families affected by CMT and health care providers.

2. Create a toolkit of resources for individuals and families affected by CMT to be housed on the National CMT Resource Center website and available in print. The toolkit will contain resources that reflect accurate and scientifically valid information on the etiology, diagnosis, and treatment of CMT, as well as links to useful resources for individuals and families affected by CMT.

· Identify experts who can review and evaluate current educational and outreach materials targeting persons affected by CMT and their families, and identify gaps in knowledge. Develop materials to address identified gaps that reflect evidence-based knowledge, expert opinion, and standards of care in clinical practice. Materials will be available in differing formats to respond to the needs of individuals and families affected by CMT. These materials may include: publications available in print and via download, such as brochures, white papers, algorithms, educational seminars, Webinars, and online training; searchable video and publication libraries; podcasts that may be archived; interactive Websites or Web portals.

3. Disseminate the toolkit to CMT patients and families.

· The recipient will ensure that a dissemination plan for the materials is developed and will describe methods for reaching underserved and minority communities, including translating Resource Center information into multiple languages, specifically Spanish, using plain language.

· Identify and collaborate with non-profit and community-based organizations that serve CMT patients and families affected by CMT, such as grassroots organizations located within the underserved targeted populations, to disseminate the toolkit.

· Dissemination should include a wide range of communication vehicles, such as: newsletters, e-newsletters, magazines, e-cards, videos, CDs, and social media (e.g., viral media, streaming video, Facebook, Myspace, Twitter, LinkedIn), as well as dissemination at targeted events.

4. Create a toolkit for health care professionals who manage health care of individuals who have CMT to be housed on the National CMT Resource Center website and available in print. The toolkit will provide a Web-based portal for health care professionals and contain resources that reflect accurate and scientifically valid information on the etiology, diagnosis, and treatment of CMT for professionals as well as links to useful resources for individuals and families affected by CMT.

· Identify experts who can review and evaluate current educational and outreach materials targeted to health care professionals, and identify gaps in knowledge. Develop materials to address identified gaps that reflect evidence-based knowledge, expert opinion, and standards of care in clinical practice. The materials should include accurate and scientifically valid information on the etiology, diagnosis, clinical course, treatment standards or guidelines, genetic counseling, and available services related to CMT. As available, materials should be specific to different types of CMT or different manifestation of CMT (axonopathy and/or myelinopathy). These materials may include: peer-reviewed literature related to clinical studies, publications available in print and via download, white papers, care-based algorithms; educational seminars, Webinars, and online training; searchable video and publication libraries; podcasts that may be archived; interactive Websites or Web portals

5. Disseminate the toolkit to health care professionals treating individuals and families affected by CMT.

· The recipient will ensure that a dissemination plan for the materials is developed and will describe methods for reaching underserved and minority communities, including translating Resource Center information into multiple languages, specifically Spanish, using plain language.

· Dissemination should include a wide range of communication vehicles, such as: newsletters, e-newsletters, magazines, e-cards, videos, CDs, and social media (e.g., viral media, streaming video, Facebook, Myspace, Twitter, LinkedIn), as well as dissemination at targeted events.

6. Conduct educational activities in coordination with organizations and professional associations, such as the American Academy of Neurology (AAN), American Academy of Family Physicians (AAFP), American Medical Association (AMA), American Association of Pediatrics (AAP), American Nurses Association (ANA), American Occupational Therapy Association (AOTA), American Physical Therapy Association (APTA), and other national and/or international organizations that offer services or direct educational messages to people who are affected by CMT and their providers. These educational activities can include: presentations at meetings; publications available in print and via download, such as white papers and algorithms; and educational seminars, Webinars, and online training. The recipient will evaluate the outcomes of the educational activities through pre- and post-tests of attendees’ knowledge of material presented during the educational activities.

7. Develop and implement a plan to evaluate the effectiveness of the National CMT Resource Center, providing an annual evaluation report. The evaluation should include both qualitative and quantitative data indicating the demographics of the population served, type of inquiries, and other relevant evaluation indicators. Evaluation measures may include: tracking social media responses; evaluating targeted groups’ CMT knowledge using print and online surveys; using Web analytics (e.g., number of unique visitors, length of visit per Web page, use of Google analytics and other internet evaluation mechanisms); and using Web or telephone surveys. The developed evaluation plan should also use the evaluation data to improve program activities in Years 2 and 3.

In a cooperative agreement, CDC staff is substantially involved in the program activities, above and beyond routine grant monitoring.

CDC Activities:

1. Provide technical guidance, consultation and assistance on the development of a National Charcot-Marie-Tooth (CMT) Resource Center.

2. Provide technical guidance, consultation and assistance on the development, dissemination, and evaluation of toolkits for individuals with CMT and families and health care professionals to include:

· review of educational and outreach materials;

· technical consultation on communication mechanisms for dissemination to all targeted populations, including underserved and minority communities, and using plain language.

3. Facilitate collaboration between the recipient and other non-profit and community-based organizations that target the national community of persons with CMT and their families, caregivers, and the health care professionals to support activities outlined in this award.

4. Facilitate collaboration between recipient and educational and professional organizations to support educational activities.

5. Provide technical assistance in evaluating the effectiveness of the National CMT Resource Center.

III. AWARD INFORMATION AND REQUIREMENTS

Type of Award: Cooperative Agreement.

CDC substantial involvement in this program appears in the Activities Section above.

Award Mechanism: U38 Fiscal Year Funds: 2010 Approximate Current Fiscal Year Funding: $ 800,000

Approximate Total Project Period Funding: $2,400,000 (This amount is an estimate, includes direct and indirect costs, and is subject to availability of funds.

Approximate Number of Awards: 1 Approximate Average Award: $800,000 (This amount is for the first 12-month budget period, and includes both direct and indirect costs Floor of Individual Award Range: None Ceiling of Individual Award Range: $800,000 (This ceiling is for the first 12-month budget period and includes direct and indirect costs.)

Anticipated Award Date: September 1, 2010 Budget Period Length: 12 months Project Period Length: 3 years Throughout the project period, CDC’s commitment to continuation of awards will be conditioned on the availability of funds, evidence of satisfactory progress by the recipient (as documented in required reports), and the determination that continued funding is in the best interest of the Federal government.

IV. ELIGIBILITY

Eligible applicants that can apply for this funding opportunity are listed below:

· Nonprofit with 501C3 IRS status (other than institution of higher education)

· Nonprofit without 501C3 IRS status (other than institution of higher education)

· For-profit organizations (other than small business)

· Small, minority, and women-owned businesses

· Universities

· Colleges

· Research institutions

· Hospitals

· Community-based organizations

· Faith-based organizations

· Federally recognized or state-recognized American Indian/Alaska Native tribal governments

· American Indian/Alaska native tribally designated organizations

· Alaska Native health corporations

· Urban Indian health organizations

· Tribal epidemiology centers

· State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau)

· Political subdivisions of States (in consultation with States)

A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a letter from the state or local government as documentation of the status is required. Attach with “Other Attachment Forms” when submitting via www.grants.gov.

SPECIAL ELIGIBILITY CRITERIA: Licensing/Credential/Permits

Cost Sharing or Matching

Cost sharing or matching funds are not required for this program.

Maintenance of Effort

Maintenance of Effort is not required for this program.

Special Requirements:

· If the application is in-complete or non-responsive to the special requirements listed in this section, it will not be entered into the review process. The applicant will be notified the application did not meet submission requirements.

· Late applications will be considered non-responsive. See Section V. “Submission Dates and Times” for more information.

Note: Title 2 of the United States Code Section 1611 states that an organization described in Section 501(c)(4) of the Internal Revenue Code that engages in lobbying activities is not eligible to receive Federal funds constituting a grant, loan, or an award.

Intergovernmental Review of Applications

Executive Order 12372 does not apply to this program.

V. Application Content

Unless specifically indicated, this announcement requires submission of the following information:

A Project Abstract must be completed in the Grants.gov application forms. The Project Abstract must contain a summary of the proposed activity suitable for dissemination to the public. It should be a self-contained description of the project and should contain a statement of objectives and methods to be employed. It should be informative to other persons working in the same or related fields and insofar as possible understandable to a technically literate lay reader. This abstract must not include any proprietary/confidential information.

A Project Narrative must be submitted with the application forms. The project narrative must be uploaded in a PDF file format when submitting via Grants.gov. The narrative must be submitted in the following format:

· Maximum number of pages: 25 If your narrative exceeds the page limit, only the first pages which are within the page limit will be reviewed.

· Font size: 12 point unreduced, Times New Roman

· Single spaced

· Paper size: 8.5 by 11 inches

· Page margin size: One inch

· Number all narrative pages; not to exceed the maximum number of pages.

· Printed only one side of page.

· Held together only by rubber bands or metal clips; not bound in any other way.

The narrative should address activities to be conducted over the entire project period and must include the following items in the order listed:

1. Background, Needs Assessment and Infrastructure- Provide relevant information on the applicant’s infrastructure, relevant experience and expertise to establish a national resource center and perform the proposed activities. Describe the need for the proposed National CMT Resource Center and how they will develop, enhance, and compliment the planned activities outlined.

2. Operational Plan and Evaluation Plan – Provide a work plan that includes objectives, methods, evaluation plans, and a timeline for each proposed activity. Objectives should be specific, measureable, achievable, realistic, and time-phased. Applicant should describe what is to happen, by when, by whom, and to what degree.

· Specific – Be precise about what you are achieving, describe a target and intended outcome.

· Measureable – Quantify your objectives…use baselines whenever possible so change can be measured.

· Achievable – Match activities with available resources.

· Realistic – Do you have the resources to make the objective happen (personnel, funds, equipment, and materials)?

· Time-phased – State when you expect to achieve the objectives.

3. Methods should describe the plan for achieving each of the objectives identified, including a description of how other organizations targeting the national community of CMT individuals will be involved.

4. Evaluation plans should include a description of how progress towards attainment of the objectives will be monitored and who will be responsible for evaluation.

5. A timeline with milestones for all objectives at a minimum should identify related activities, start and completion dates, and the name of person (s) responsible for achievement/implementation.

6. Management and Staffing Plan – Describe how the program will be effectively managed. Include the following:

· Management structure including the lines of authority and plans for fiscal control.

· The staff positions responsible for implementation.

· Qualifications and experience of the designated staff.

7. Budget justification – Provide a detailed budget request and line item justification of all proposed operating expenses. The budget and budget justification will be included as a separate attachment, not to be counted in the narrative page limit.

Additional information may be included in the application appendices. The appendices will not be counted toward the narrative page limit. This additional information includes:

· Curriculum Vitae

· Resumes

· Organizational Charts

· Letters of Support

· Educational Material Examples

· Indirect Cost Rate Agreement

Additional information submitted via Grants.gov should be uploaded in a PDF file format, and should be named:

· “Other Attachments Forms” to be titled/named when uploaded under Mandatory Documents into Grants.gov (i.e., Curriculum vitae, Resumes, Organizational Charts, Letters of Support, Educational Material Examples, and Indirect Cost Rate Agreement.).

No more than 15 allowable electronic attachments should be uploaded per application.

Additional requirements for additional documentation with the application are listed in Section VII. Award Administration Information, subsection entitled “Administrative and National Policy Requirements.”

APPLICATION SUBMISSION

Registering your organization through www.Grants.gov, the official agency-wide E-grant website, is the first step in submitting an application online. Registration information is located on the “Get Registered” screen of www.Grants.gov. Please visit www.Grants.gov at least 30 days prior to submitting your application to familiarize yourself with the registration and submission processes. The “one-time” registration process will take three to five days to complete. However, the Grants.gov registration process also requires that you register your organization with the Central Contractor Registry (CCR) annually. The CCR registration can require an additional one to two days to complete.

Submit the application electronically by using the forms and instructions posted for this funding opportunity on www.Grants.gov. If access to the Internet is not available or if the applicant encounters difficulty in accessing the forms on-line, contact the HHS/CDC Procurement and Grant Office Technical Information Management Section (PGO-TIMS) staff at (770) 488-2700 for further instruction.

Note: Application submission is not concluded until successful completion of the validation process.

After submission of your application package, applicants will receive a “submission receipt” email generated by Grants.gov. Grants.gov will then generate a second e-mail message to applicants which will either validate or reject their submitted application package. This validation process may take as long as two (2) business days. Applicants are strongly encouraged check the status of their application to ensure submission of their application package is complete and no submission errors exists. To guarantee that you comply with the application deadline published in the Funding Opportunity Announcement, applicants are also strongly encouraged to allocate additional days prior to the published deadline to file their application. Non-validated applications will not be accepted after the published application deadline date.

In the event that you do not receive a “validation” email within two (2) business days of application submission, please contact Grants.gov. Refer to the email message generated at the time of application submission for instructions on how to track your application or the Application User Guide, Version 3.0 page 57.

Other Submission Requirements

Letter of Intent (LOI):

A letter of intent is not applicable to this funding opportunity announcement.

Dun and Bradstreet Universal Number (DUNS)

The applicant is required to have a Dun and Bradstreet Data Universal Numbering System (DUNS) identifier to apply for grants or cooperative agreements from the Federal government. The DUNS is a nine-digit number which uniquely identifies business entities. There is no charge associated with obtaining a DUNS number. Applicants may obtain a DUNS number by accessing the Dun and Bradstreet website or by calling 1-866-705-5711.

Electronic Submission of Application:

Applications must be submitted electronically at www.Grants.gov. Electronic applications will be considered as having met the deadline if the application has been successfully submitted electronically by the applicant organization’s Authorized Organizational representative (AOR) to Grants.gov on or before the deadline date and time.

The application package can be downloaded from www.Grants.gov. Applicants can complete the application package off-line, and then upload and submit the application via the Grants.gov Web site. The applicant must submit all application attachments using a PDF file format when submitting via Grants.gov. Directions for creating PDF files can be found on the Grants.gov Web site. Use of file formats other than PDF may result in the file being unreadable by staff.

Applications submitted through Grants.gov (http://www.grants.gov), are electronically time/date stamped and assigned a tracking number. The AOR will receive an e-mail notice of receipt when HHS/CDC receives the application. The tracking number serves as a receipt of submission.

If problems are encounters with Grants.gov, the applicant should contact Grants.gov Customer Service. The Grants.gov Contact Center is available 24 hours a day, 7 days a week. The Contact Center provides customer service to the applicant community. The extended hours will provide applicants support around the clock, ensuring the best possible customer service is received any time it’s needed. You can reach the Grants.gov Support Center at 1-800-518-4726 or by email at support@grants.gov. Submissions sent by e-mail, fax, CD’s or thumb drives of applications will not be accepted.

Submission Dates and Times

This announcement is the definitive guide on LOI and application content, submission, and deadline. It supersedes information provided in the application instructions. If the application submission does not meet the deadline published herein, it will not be eligible for review and the applicant will be notified the application did not meet the submission requirements. The application face page will be returned by HHS/CDC with a written explanation of the reason for non-acceptance.

Application Deadline Date: May 14, 2010 ON GRANTS.GOV, 11:59pm Eastern Standard Time.

VI. Application Review Information

Eligible applicants are required to provide measures of effectiveness that will demonstrate the accomplishment of the various identified objectives of the Funding Opportunity Announcement Number DD10-1014. Measures of effectiveness must relate to the performance goals stated in the “Purpose” section of this announcement. Measures of effectiveness must be objective, quantitative and measure the intended outcome of the proposed program. The measures of effectiveness must be included in the application and will be an element of the evaluation of the submitted application.

Evaluation Criteria Eligible applications will be evaluated against the following criteria:

Operational and Evaluation Plan (60 Points) Does the applicant’s work plan include goals and SMART objectives, quantitative process, and outcome measures for all proposed activities. How feasible are the applicant’s proposed methods and to what extent will they accomplish the program goals? How well will the activities proposed achieve program goals and how well does the applicant anticipate and utilize innovative and valued approaches in meeting all requirements of the announcement? How complete is the applicant’s evaluation plan for the design and management of the activities proposed? How complete and comprehensive is the plan for the entire project period?

Background, Need, and Infrastructure (20 Points) Does the applicant provide a narrative, including background information on the history, mission, and reach of the organization? Based on the narrative, does this organization have the capacity, culture, and infrastructure to successfully carryout this project? Does the applicant demonstrate an understanding of the purpose of the cooperative agreement?

Project Management and Staffing Plan (20 Points) Does the applicant provide a management plan that includes the organizational structure with staff positions detailing roles and responsibilities, clear lines of authority and plans for fiscal control, and that designated staff proposed to be involved in the project have appropriate qualifications with evidence of experience and evidence of past achievements appropriate to a project of this magnitude and scope? Will the stated responsibilities for personnel and the proposed staffing functions assure adequate progress toward meeting all goals and objectives?

Budget (Not scored) To what extent does the applicant provide justification for budget expenditures was well as appropriateness to activities proposed in the application. The budget will be evaluated for the extent that it is reasonable, clearly justified, and consistent with the intended use of the funds.

Budget (SF 424A) and Budget Narrative (Reviewed, but not scored) Although the budget is not scored applicants should consider the following in development of their budget. Is the itemized budget for conducting the project, and justification reasonable and consistent with stated objectives and planned program activities?

If the applicants requests indirect costs in the budget, a copy of the indirect cost rate agreement is required. If the indirect cost rate is a provisional rate, the agreement should be less than 12 months of age. The indirect cost rate agreement should be uploaded as a PDF file with “Other Attachment Forms” when submitting via Grants.gov Funding Restrictions Restrictions, which must be taken into account while writing the budget, are as follows:

· Recipients may not use funds for research.

· Recipients may not use funds for clinical care.

· Recipients may only expend funds for reasonable program purposes, including personnel, travel, supplies, and services, such as contractual.

· Awardees may not generally use HHS/CDC/ATSDR funding for the purchase of furniture or equipment. Any such proposed spending must be identified in the budget.

· The direct and primary recipient in a cooperative agreement program must perform a substantial role in carrying out project objectives and not merely serve as a conduit for an award to another party or provider who is ineligible.

· Reimbursement of pre-award costs is not allowed.

The recommended guidance for completing a detailed justified budget on the CDC website, at the following Internet address:

http://www.cdc.gov/od/pgo/funding/budgetguide.htm.

Application Review Process

All eligible applications will be initially reviewed for completeness by the Procurement and Grants Office (PGO) staff. In addition, eligible applications will be jointly reviewed for responsiveness by the National Center on Birth Defects and Developmental Disabilities (NCBDDD) and PGO. Incomplete applications and applications that are non-responsive to the eligibility criteria will not advance through the review process. Applicants will be notified the application did not meet eligibility and/or published submission requirements.

An objective review panel will evaluate complete and responsive applications according to the criteria listed in Section VI. Application Review Information, subsection entitled “Evaluation Criteria”. The objective review process will follow the policy requirements as stated in the GPD 2.04 at http://198.102.218.46/doc/gpd204.doc. Applications will be reviewed objectively by a minimum of three qualified independent reviewers. A primary, secondary, and tertiary objective reviewer will assess each full application using only the criteria published in this announcement. One consistent voting panel will vote on all applications, presided over by a non-voting chairperson. All objective reviewers and panel members will be CDC employees external to the Team funding this announcement.

Applications Selection Process

In addition, the following factors may affect the funding decision:

Preference to organizations currently providing educational activities and linkage to services for the targeted national community of persons with CMT and their families, preference to organizations that currently have the capacity to establish a national resource center, and preference to organizations that are currently collaborating with other organizations that provide services to the targeted national community of persons with CMT and their families as well as health care professionals.

CDC will provide justification for any decision to fund out of rank order.

VII. Award Administration Information Award Notices

Successful applicants will receive a Notice of Award (NoA) from the CDC Procurement and Grants Office. The NoA shall be the only binding, authorizing document between the recipient and CDC. The NoA will be signed by an authorized Grants Management Officer and e-mailed to the program director. A hard copy of the NoA will be mailed to the recipient fiscal officer identified in the application.

Unsuccessful applicants will receive notification of the results of the application review by mail.

Administrative and National Policy Requirements

Successful applicants must comply with the administrative requirements outlined in 45 Code of Federal Regulations (CFR) Part 74 or Part 92, as appropriate. The following additional requirements apply to this project:

· AR-9

Paperwork Reduction Act Requirements

· AR-11

Healthy People 2010

· AR-12

Lobbying Restrictions

· AR-14

Accounting System Requirements

· AR-15

Proof of Non-Profit Status

· AR-20

Conference Support

· AR-21

Small, Minority, and Women-Owned Business

· AR-23

States and Faith-Based Organizations

· AR-27

Conference Disclaimer and Use of Logos

Additional information on the requirements can be found on the CDC Web site at the following Internet address: http://www.cdc.gov/od/pgo/funding/Addtl_Reqmnts.htm.

For more information on the Code of Federal Regulations, see the National Archives and Records Administration at the following Internet address: http://www.access.gpo.gov/nara/cfr/cfr-table-search.html CDC Assurances and Certifications can be found on the CDC Web site at the following Internet address: http://www.cdc.gov/od/pgo/funding/grants/foamain.shtm

TERMS AND CONDITIONS

Reporting Requirements

Each funded applicant must provide CDC with an annual Interim Progress Report submitted via www.grants.gov:

1. The interim progress report is due no less than 90 days before the end of the budget period. The Interim Progress Report will serve as the non-competing continuation application, and must contain the following elements:

a. Standard Form (“SF”) 424S Form.

b. SF-424A Budget Information-Non-Construction Programs.

c. New Budget Period Narrative including:

· New proposed program activities, showing timeline, and staff

· Detailed budget for non-competing continuation

· Identify estimated unobligated funds in the current budget period by component separately on the 424A Forms and provide detail actions to be taken to obligate the funds.

d. Indirect Cost Rate Agreement.

e. Current Project Period Narrative including:

· Current budget period activities, showing timelines, and staff

· Current budget period interim financial status report.

Additionally, funded applicants must provide CDC with an original, plus two hard copies of the following reports:

2. Annual progress report, due 90 days after the end of the budget period, before submission of the FSR

· Current Budget Period Activities: For each activity, provide a brief report that reflects current status, any barriers encountered, and how the barriers were addressed. If applicable, include the reasons that activities were not accomplished according to timeline submitted, and a discussion of any assistance needed to resolve the situation.

· Other Program Information: (a) programmatic shifts and/or revision in operational plan and methods, staffing, and the impact on program status.

3. Financial Status Report (SF 269), no more than 90 days after the end of the budget period.

4. Final performance and Financial Status Reports, no more than 90 days after the end of the project period.

These reports must be submitted to the attention of the Grants Management Specialist listed in the Section VIII below entitled “Agency Contacts”.

VIII. Agency Contacts

CDC encourages inquiries concerning this announcement.

For programmatic technical assistance, contact:

Carolyn Constantin, Project Officer

Department of Health and Human Services

Centers for Disease Control and Prevention

1600 Clifton Road, NE, MS E-88

Atlanta, GA 30333

Telephone: (404) 498-1447

E-mail: bma2@cdc.gov For financial, grants management, or budget assistance, contact:

Lucy Picciolo, Grants Management Specialist

CDC Procurement and Grants Office

2920 Brandywine Road, MS E-09

Atlanta, GA 30341

Telephone: 770-488-2683

E-mail: LIP6@cdc.gov For general questions, contact:

Technical Information Management Section

CDC Procurement and Grants Office

2920 Brandywine Road, MS E-14

Atlanta, GA 30341

Telephone: 770-488-2700

Email:

pgotim@cdc.gov

CDC Telecommunications for the hearing impaired or disabled is available at: TTY 770-488-2783.

Other Information Information cited in the Background section was cited from http://www.ninds.nih.gov/disorders/charcot_marie_tooth/detail_charcot_marie_tooth.htm Charcot-Marie-Tooth Disease Fact Sheet from the National Institute of Health’s National Institute of Neurological Disorders and Stroke (last updated December 18, 2009).

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