B08 - IDIQ-MECS.docx
DOCX document 26 KB Posted
- Attached to
- Kilobaser Equipment and Consumables
- Solicitation number
- HT9425-25-QE010
- Issued by
-
Defense Health Agency
About this file
This document is a Minimal Essential Characteristics (MEC) file for an Indefinite Delivery/Indefinite Quantity (IDIQ) contract solicited by multiple U.S. military research laboratories, including USAMRIID, MRICD, and WRAIR. The procurement seeks Kilobaser DNA/RNA Synthesizers, Nitrogen Generators, and associated reagents with a 5-year ordering period. Key requirements include portable equipment (50 lbs or less, 15" x 15" x 15" dimensions) with specific performance capabilities such as producing oligonucleotides within four hours, high coupling efficiency (99.5%), and remote service support within 24 hours.
The solicitation covers multiple product categories including synthesizers, nitrogen generators, DNA/RNA cartridges, microfluidic chips, and purification kits with detailed technical specifications for each item. Delivery is specified to the United States Army Medical Research Institute for Infectious Diseases in Fort Detrick, MD, with coordination contacts being Dr. Jeffrey Koehler and Dr. Mariano Sanchez-Lockhart. The related federal contract opportunity is managed by the Defense Health Agency, with the solicitation number HT9425-25-QE010, focusing on procurement of advanced oligonucleotide synthesis equipment with associated software, training, and consumables.
View the file
Other files
| File | Type | Posted |
|---|---|---|
| Solicitation Amendment HT942525QE0100001 SF 30.pdf | ||
| Solicitation Amendment HT942525QE0100002 SF 30.pdf | ||
| B08 - Delivery Order 1 Pricing Sheet.xlsx | XLSX spreadsheet | |
| B08 - IDIQ Pricing Sheet.xlsx | XLSX spreadsheet | |
| B08 - Delivery Order 1- MECs.docx | DOCX document | |
| B08 - Ordering Instructions and GPC Information.docx | DOCX document | |
| B08 - ADDENDUM TO 52.212-1 – INSTRUCTIONS TO OFFERORS - COMMERCIAL PRODUCTS AND COMMERCIAL SERVICES.docx | DOCX document | |
| B08 -HT942525QE010_Solicitation_Final_08.15.2025.pdf |
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Text version
United States Army Medical Research Institute for Infectious Diseases (USAMRIID) Medical Research Institute of Chemical Defense (MRICD) Walter Reed Army Institute of Research (WRAIR) Minimal Essential Characteristics (MEC) USAMRIID, MRICD, WRAIR, and any Research Laboratory under Medical Research and Development Command or Defense Health Agency request Kilobaser Deoxyribonucleic Acid (DNA)/Ribonucleic Acid (RNA) Synthesizers, Kilobaser Nitrogen Generators and associated reagents via an Indefinite Delivery/Indefinite Quantity (IDIQ), 5-year ordering period meeting the following MECs:
1) Nitrogen Generators shall be:
Size:
· Generator must be easily portable (50lbs or less) and shall not exceed dimensions of 15” x 15” x 15” due to limited benchtop space and portability requirements.
· The instrument must be capable of being carried by a person to a remote location.
Performance:
· Generator must be capable of working in conjunction with Kilobaser ONE-XT DNA and RNA Synthesizer.
· Generator must produce the necessary nitrogen required to operate the Kilobaser ONE-XT DNA and RNA Synthesizer to synthesize DNA and RNA.
· Generator must operate with the Kilobaser ONE-XT DNA and RNA Synthesizer as provided.
Service:
· The contractor shall provide service remotely within 24 hours. If the Kilobaser Nitrogen Generator G2N cannot be repaired remotely, a new device shall be supplied within one week during the one-year warranty period. Each purchase price shall include a one-year warranty.
· All software licensing, warranty, and services associated with the equipment shall be in accordance with Original Equipment Manufacturer (OEM) terms and conditions.
2) Kilobaser DNA/RNA synthesizer shall be:
Size: Synthesizer must be easily portable (~50lbs or less) and must not exceed dimensions of 15” x 15” x 15” due to limited benchtop space.
Performance:
· Synthesizer must be capable of producing oligonucleotides in less than approximately four (4) hours.
· Synthesizer must be capable of producing DNA, DNA probes, modified DNA, and modified RNA.
· Synthesizer must have coupling efficiency comparable to or above industry average of approximately 99.5%.
Service:
· The contractor shall provide service remotely within 24 hours. If Synthesizer cannot be repaired remotely, a new device shall be supplied within one week during the one-year warranty period. Each purchase price shall include a one-year warranty.
· All software licensing, warranty, and services associated with the equipment shall be in accordance with Original Equipment Manufacturer (OEM) terms and conditions.
3) 6FAM DNA Cartridge shall be compatible with the Kilobaser DNA/RNA Synthesizer for the synthesis of DNA oligonucleotides with a 6FAM modification.
4) Standard DNA cartridge shall be compatible with the Kilobaser DNA/RNA Synthesizer for the synthesis of DNA oligonucleotides.
5) 6FAM Label Chip shall be compatible with the Kilobaser DNA/RNA Synthesizer for the synthesis of DNA oligonucleotides with a 6FAM modification.
6) BHQ1 Quencher Chip shall be compatible with the Kilobaser DNA/RNA Synthesizer for the synthesis of DNA oligonucleotides with a BHQ1 quencher modification.
7) OilPure HIC Column Oligo Purification Kit compatible with the Kilobaser DNA/RNA Synthesizer for the column-based purification of synthesized oligonucleotides.
8) Biotin – Cartridge shall be compatible with the Kilobaser DNA/RNA Synthesizer for the synthesis of biotin-labelled oligonucleotides.
9) Biotin – Chip shall be compatible with the Kilobaser DNA/RNA Synthesizer for the synthesis of biotin-labelled oligonucleotides.
10) Phosphorylation – Cartridge shall be compatible with the Kilobaser DNA/RNA Synthesizer for the synthesis of biotin-labelled oligonucleotides.
11) 2’-MOE RNA Reagent Cartridge shall be compatible with the Kilobaser DNA/RNA Synthesizer for the RNA oligonucleotides.
12) OliPure HIC Column Oligo Purification Kit shall be compatible with the Kilobaser DNA/RNA Synthesizer for the bead-based purification of synthesized oligonucleotides.
13) Additional new Kilobaser supplies and reagents shall be compatible with the Kilobaser DNA/RNA Synthesizer and the Kilobaser Nitrogen generator.
| Item |
| Requirement |
| Kilobaser one |
| Synthesize non-modified DNA oligonucleotides |
| Kilobaser one-XT |
| Synthesize DNA and RNA oligonucleotides |
| Kilobaser Nitrogen Generator |
| Generate nitrogen for use with the Kilobaser one/one-XT |
| Standard DNA reagent cartridge |
| Synthesize DNA oligonucleotides |
| 6FAM reagent cartridge |
| Synthesize 56FAM modified DNA oligonucleotides |
| Biotin reagent cartridge |
| Synthesize 5'-biotin modified DNA oligonucleotides |
| Phosphorylation reagent cartridge |
| Synthesize 5'-phosphate modified DNA oligonucleotides |
| Amino modifier C6 reagent cartridge |
| Synthesize C6 linker DNA oligonucleotides |
| 2'-MOE RNA reagent cartridge |
| Synthesize 2'-MOE RNA oligonucleotides |
| 2'-Ome RNA reagent cartridge |
| Synthesize 2'-OM2 RNA oligonucleotides |
| 2'-F RNA reagent cartridge |
| Synthesize 2'-flouro RNA oligonucleotides |
| Standard microfluidic chip |
| Used for the synthesis of PCR primers |
| 6-FAM label microfluidic chip |
| Used for the synthesis of 56FAM modified PCR primers |
| BHQ1 Quencher microfluidic chip |
| Used to generate BHQ1 quenched DNA oligonucleotides |
| Amino modifier C6 microfluidic chip |
| Used for the synthesis of C6 modified DNA oligonucleotides |
| Biotin label microfluidic chip |
| Used for the synthesis of 5'-biotin modified DNA oligonucleotides |
| Phosphorylation microfluidic chip |
| Used for the synthesis 5'-phosphate modified DNA oligonucleotides |
| OilPure HIC purification kit |
| Used for the purification of Kilobaser synthesized oligonucleotides |
Delivery Requirements Items shall be shipped to:
United States Army Medical Research Institute of Infectious Diseases (USAMRIID) 1425 Porter Street Fort Detrick, MD 21702
Delivery of items shall be coordinated with:
Name: Dr. Jeffrey Koehler/Dr. Mariano Sanchez-Lockhart Email: jeffrey.w.koehler4.civ@health.mil/ mariano.sanchez-lockhart.civ@health.mil Phone: (301) 619-8342/(301) 619-3279
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