Attachment 1 Specification Document 12805B23Q0434.pdf

Sheep Page | 4

SOW with Specifications for Sheep Order

Foot-and-mouth disease (FMD) is an important disease of livestock that is caused by foot-and-mouth disease virus (FMDV). The relevance of sheep as susceptible hosts capable of propagating FMD outbreaks is often overlooked, despite documented involvement of sheep as a major factor in multiple FMD epidemics. It is unknown how early or persistent FMDV infection of sheep contributes to evolution of the virus and to potential generation of novel FMDV variants. The purpose of procuring the sheep described herein is to perform 1 animal experiment in which sheep will be inoculated with one or two distinct strains of FMDV in order to understand how the viruses interact with the sheep immune systems. Sheep will be followed for up to 6 weeks after infection and samples will be collected to characterize the evolution of the viruses and changes in host factors over the course of the experiment. Infection dynamics will be characterized during the acute and persistent phases of infection.

ANIMAL REQUIREMENTS

Sheep

• Sheep must originate from a closed herd.

• Sheep should weigh 60-80 lbs unless specified otherwise.

• Sheep must be open females or castrated males unless specified otherwise.

• Sheep should have white feet and mouth.

• Sheep must be polled or dehorned, tolerate being haltered, have a tractable temperament, and be free of behavioral vices such as charging and kicking.

• Feet must be trimmed prior to shipment if necessary.

• Sheep must receive selenium and iron injections at 5-7 days of age.

• Sheep must be Q fever (Coxieila burnetii) tested and negative.

• Flock of origin must be free of para pox (Orf, sore mouth)

• Mandatory Vaccinations:

CD&T Clostridium vaccine (5 way or 7 way) which includes

• Clostridium perfringens Type C&D and tetanus toxoid, and boosters as necessary. Sheep should also receive vaccination against Mannheimia (Pasteurella) haemolytica.

• In addition, based on risk of exposure, sheep should receive vaccinations against caseous lymphadenitis, foot rot and sore mouth.

• Sheep must be fully shorn prior to delivery unless specified otherwise.

• Sheep must be free of external parasites and have been dewormed within one month of delivery.

• Sheep must receive appropriate antifungal and antiparasitic drugs as needed.

• Sheep on day of delivery are to be healthy with no overt signs of disease, e.g. respiratory disease, lameness, and parasites.

• Sheep must receive 1 dose of appropriate, long-acting antibiotics prior to shipping to prevent shipping fever unless otherwise specified.

ACEPTANCE/REJECTION OF ANIMALS

• Sheep will be evaluated after 7 days quarantine. In the event of illness after appropriate incubation time the government shall submit an Animal

Incident Report by fax within 5 business days. In the event of death, an Animal

Incident Report will be faxed to the vendor within 48 hours after death of the animal.

• Animals that show clinical signs of illness that are due to the husbandry may be treated or humanely destroyed if the illness has progressed to a point when death is certain to occur regardless of therapeutic intervention. A credit will be required from the contractor within 48 hours after receipt of the Animal Incident Report noting time of death. If it is medically determined that illness or death of an animal is caused by a condition present prior to delivery, replacement of the animal(s) including shipment shall be required or credit issued at the agency’s choice within

24 hours of generation of Animal Incident Report.

ANIMALS CANNOT BE REMOVED ONCE THEY REACH THE ORIENT POINT

FACILITY IN ACCORDANCE WITH DHS AND ARS POLICY.

DELIVERY REQUIREMENTS

The Contractor shall furnish and deliver (F.O.B. Origin) the animals within the negotiated time frame on each request and documentation to the

USDA, ARS, NAA, PIADC, 40550 Rt. 25, Warehouse facility, Orient Point, NY

11957. Delivery shall be between the hours of 06:00 a.m. to 11:00 a.m., Tuesday thru Thursday, excluding Federal holidays. Orient Point facility access is through the east gate which is guarded by security The

Contractor shall unload animals via a supplied wooden animal stockade ramp into the back of a government provided animal transport trailer.

• Contractor employee(s) must adhere to facility safety regulations.

• Transportation of animals should be planned to:

• minimize transit time and the risk of zoonoses

• protect against environmental extremes

• avoid overcrowding

• provide food and water when indicated

• protect against physical trauma.

• The transportation, care, and use of animals should be in accordance with the Animal Welfare Act (7 U.S.C. 2131 et. seq.) and other applicable Federal laws, guidelines, and policies. For guidance refer to The

Care and Use of Laboratory Animals prepared by the Institute for

Laboratory Animal Research, National Academy of Science

• Sheep are to be delivered per the “Animal Welfare Act Regulations

Pertaining to Transportation, 9 CFR 3.112‐3.118,” “GUINEA PIGS AND

HAMSTERS, RABBITS, AND OTHER ANIMALS (9 CFR 3.35‐3.41, 9 CFR 3.60‐

3.65, 9

CFR 3.136‐3.142”.

• Animals that are injured due to transportation shall be humanely destroyed by the government.

After receipt of the Animal Incident Report replacement of cattle including shipping shall be required or credit issued at the agency’s discretion within 48 hours.

• GOV is responsible for providing the transportation of the animals from the Orient Point facility parking lot to the Plum Island building 101 laboratories.

• Hazardous Weather Alert. The Contractor shall be required to contact the PIADC weather announcement line at 631‐323‐3323 prior to shipment due to potential marine weather conditions which will restrict completion of the deliveries. Contractor is liable for all costs if delivery is delayed due to hazardous weather.

ADDITIONAL REQUIREMENTS

• Section 508 Accessibility Compliance Clause ‐ Does not Apply

• WARRANTY – Not Applicable

• DOCUMENTATION – The Contractor shall provide the following:

• Prior to shipment to PIADC, a veterinary examination and issuance of the interstate/intrastate health certificate for shipment shall be provided with delivery. The health certificate shall include at a minimum, general information identifying the animal by number/id;

the departure date of transport to the Plum Island Orient Point

Warehouse Facility; Breed; Gender; Age or Birth Date Range;

Dehorned; Weaned; Castrated (if applicable); the dates and dosages of vaccines and anti‐parasitic, anti‐fungal, antibiotic drugs; any other tests and corresponding results; and any other relevant information.

• Veterinarian certification of recent medical history and treatments given to animals with delivery.

• Contact information for attending veterinarian for means of evaluating the vendor’s animal care history.

• Freight ‐ FOB Destination. (Must be reassessed if multiple agencies combine deliveries.)

• Performance ‐ The Contractor shall furnish and deliver the animals in accordance with the specifications by the due

EVALUATION CRITERIA

Best Value ‐ A selection process which is used to determine which offer is the best trade‐off between price/cost and performance capabilities where quality is considered an integral performance factor. In essence, it is getting the best deal for our money, all factors considered.

Award will be made to the offeror offering the "best value" to the

Government, price and the identified "technical factors" considered. All of the technical factors combined are significantly more important than price; however, in the event that offerors are considered essentially equal in terms of technical competence price may become the determining factor in contract selection.

The following evaluation criteria shall be used: Technical Capability, Past

Performance and Price.

TECHNICAL CAPABILITY OF THE FIRM ‐ the Contractor’s capability to meet the specifications, including quality, to meet the Agency's need, documentation, delivery time frames and a minimum 3 years animal livestock/laboratory production. The SAMS website will be used to verify the Contractor’s Business Start Date for evaluation of the minimum business requirement. Travel duration shall be a factor in determining a contractor’s availability to provide research animals.

2)

PAST PERFORMANCE. Past performance history may be based on the Gove rnment’s knowledge of any previous purchases of this type of acquisition, customer surveys, and previous purchases with the Contractor, or any other verifiable information available to the Contracting Officer.

3)

PRICE. Price includes all animals; testing; ear tags; inoculations, as requir ed; transportation; and any discount terms offered.