About this file

This is a business proposal template spreadsheet for pricing various research activities related to immunotoxicity assessment. The template includes tabs for base work and optional items across a base year, nine option years, and a 6-month extension period. The pricing structure covers four main components: Contract Administration, Research Outline I (In Vitro Screening Studies), Research Outline II (Lycopene Developmental Immunotoxicity Studies), and In Vitro Hypersensitivity testing, plus an optional Research Outline III for novel tools development.

The template requires contractors to input labor rates, fringe benefits, overhead costs, G&A, and fee percentages. It includes sections for direct labor hours and costs, materials/supplies, travel expenses (specifically to STP 2024 in Baltimore and SOT 2024 in Salt Lake City), subcontractor costs (up to 10 subcontractors), and consultant costs. The file is structured as a fill-in template with yellow highlighted cells for data entry and contains built-in formulas to calculate total costs across all contract periods.

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Instruction Tab

Instructions:

Please fill in yellow highlighted cells on each tab. Do not update formulas unless necessary. If formulas are updated, please leave a comment/note on that tab so it will be clearly seen.

Summary Overall Summary

YearBase Work (Contract Admin, ROI, RO II, In Vitro Hypersens.)Optional Item (add LoE)Total Base + Optional LOEOptional Item - ROIIITotal Base + All Options
Base Year$ -$ -$ -$ - 0$ -
Option Year 1$ - 0$ - 0$ -$ - 0$ -
Option Year 2$ - 0$ - 0$ -$ - 0$ -
Option Year 3$ - 0$ - 0$ -$ - 0$ -
Option Year 4$ - 0$ - 0$ -$ - 0$ -
Option Year 5$ - 0$ - 0$ -$ - 0$ -
Option Year 6$ - 0$ - 0$ -$ - 0$ -
Option Year 7$ - 0$ - 0$ -$ - 0$ -
Option Year 8$ - 0$ - 0$ -$ - 0$ -
Option Year 9$ - 0$ - 0$ -$ - 0$ -
Optional 6-month Extension$ - 0$ -$ -
Grand Total$ -$ -$ -$ -$ -

All information on this tab flows from other tabs. Do not edit this tab. Please notify the contracting officer if there is a formula error.

Rates

Rates for Base Year
Fringe
Overhead
Overhead- Onsite/remote
G&A
Fee
Option Year escalation

Instructions: Insert indirect rates into the applicable yellow boxes. Rates will flow through to applicable tabs.

Contract Admin Research Outline for Administrative Support/Contract Administration

Base Work
Direct Laborhoursxrate ($/hr)dollars
Professionalx=$ -
Technicalx=$ -
Total Hours and Direct Labor Cost0$ -
with Fringe$ -
with Overhead$ -
Other Direct Costs$ -
Materials/Supplies$ -
Total Direct/Indirect$ -
Gen & Administrative$ -
Total with G&A$ -
Fee$ -
Total per Project (Base Year 1)$ -
Years multiplier (typically 1)1
Grand Total$ -

Assumptions

Assumptions for this RO
Use for activities associated with overall contract management and coordination, such as preparing monthly status reports, monthly budget summary reports, invoices, and the contract annual report; planning for and attending periodic progress meetings with the Government; maintaining contract and research records; onboarding/offboarding Contractor staff; software license fees, etc. Also use for activities associated with functional unit management and coordination.

Instructions: Insert estimated hours and labor rates into the applicable yellow boxes. Please note any assumptions or formula changes on this tab in the yellow note box below. Please do this for all tabs.

Sample RO I Sample Research Outline I. In Vitro Screening Studies to Evaluate Immune Suppression

Base WorkOptional ItemTotal Base & Optional Item
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x=$ -
Technicalx=$ -x=$ -
Total Hours and Direct Labor Cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs$ -$ -
Materials/Supplies$ -$ -
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per Project (Base Year 1)$ -$ -
Total Projects per Year11
Grand Total$ -$ -$ -

Assumptions

Sample RO II Sample Research Outline II: Screening Studies to Evaluate the Potential of Lycopene (CASRN: 502-65-8) to Induce Developmental Immunotoxicity in HSD:Sprague Dawley Rats Following Oral Administration

Base WorkOptional ItemTotal Base & Optional Item
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x=$ -
Technicalx=$ -x=$ -
Total Hours and Direct Labor Cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs$ -$ -
Materials/Supplies$ -
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per Project (Base Year 1)$ -$ -
Total Projects per Year10
Grand Total$ -$ -$ -

Assumptions

In Vitro Hypersensitivity Non-RO Activity: Evaluation of the Potential to Induce Hypersensitivity Using In Vitro Assays

Base WorkOptional ItemTotal Base & Optional Item
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x=$ -
Technicalx=$ -x=$ -
Total Hours and Direct Labor Cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs$ -$ -
Materials/Supplies$ -
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per Project (Base Year 1)$ -$ -
Total Projects per year11
Grand Total$ -$ -$ -

Assumptions

Sample RO III Sample Research Outline III. Proof of Concept: Development and Evaluation of Novel Tools and Methods to Assess Immunotoxicity In Vitro (OPTIONAL ITEM)

Base Work
Direct Laborhoursxrate ($/hr)
Professionalx=$ -
Technicalx=$ -
Total Hours and Direct Labor Cost0$ -
with Fringe$ -
with Overhead$ -
Other Direct Costs$ -
Materials/Supplies$ -
Total Direct/Indirect$ -
Gen & Administrative$ -
Total with G&A$ -
Fee$ -
Total per Project (Base Year 1)$ -
Total Projects per Year1
Grand Total$ -

Assumptions

Travel Contract Other Direct Costs

Base Work
Contractor Travel to STP 2024 (Baltimore, MD)UnitsUnitsUnits
Travel to NTP Archives$##$
Airfareper personXpersons$0
Lodgingper personXpersonsXnights$0
Per diemper personXpersonsXday$0
Miscelleneous
Miscelleneous (to cover airport parking, ground transportation, tolls, telephone)per dayXpeopleXday$0
BaggageXpeople$0
Total$0
With Gen & Administrative$0
With Fee$0
Travel to STP 2024 GRAND TOTAL
Total Projects per year1$0
Base Work
Contractor Travel to SOT 2024 (Salt Lake City, UT)UnitsUnitsUnits
Travel to NTP Archives$##$
Airfareper personXpersons$0
Lodgingper personXpersonsXnights$0
Per diemper personXpersonsXday$0
Miscelleneous
Miscelleneous (to cover airport parking, ground transportation, tolls, telephone)per dayXpeopleXday$0
BaggageXpeople$0
Total$0
With Gen & Administrative$0
With Fee$0
Travel to SOT 2024 GRAND TOTAL
Total Projects per year1$0

Subcontractors

SUMMARY OF SUBCONTRACTOR COSTS
SUBCONTRACT #Base PeriodBase Period - Optional LOE IncreaseOptional Sample RO III
(1)$0$0$0
(2)000
(3)000
(4)000
(5)000
(6)000
(7)000
(8)000
(9)000
(10)000
TOTAL =$0$0$0
A complete breakdown and summary sheet for each proposed subcontract must
be included with the prime proposal. The same format should be used for both
the prime and subcontract proposals.

Consultants

SUMMARY OF CONSULTANT COSTS
Base PeriodBase Period - Optional LOE IncreaseOptional Sample RO III
CONSULTANTRate# Hours# DaysTravelSubtotalCONSULTANTRate# Hours# DaysTravelSubtotalCONSULTANTRate# Hours# DaysTravelSubtotal
(1)(1)(1)
(2)(2)(2)
(3)(3)(3)
(4)(4)(4)
(5)(5)(5)
(6)(6)(6)
(7)(7)(7)
(8)(8)(8)
(9)(9)(9)
(10)(10)(10)
TOTAL =$0TOTAL =$0TOTAL =$0
Note: Please provide detailed support for all items, especially travel on this tab.

File details come from the government source that posted it. Updated .