Appendix A - ARPA-H Solutions Summary Template-Amend-2.docx

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Proactive Health Office (PHO) Mission Office Innovative Solutions Opening (ISO)
Solicitation number
ARPA-H-SOL-24-106
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This document is an Appendix A template for a Solution Summary for the ARPA-H Proactive Health Office (PHO) Mission Office Innovative Solutions Opening (ISO). The template provides a structured format for organizations to submit proposals addressing population-level health improvements, focusing on disease prevention, wellness-promoting behaviors, early-detection methods, and systemic health innovations. Submissions must be in English, use sans serif font, and are limited to six pages, with specific sections including a concept summary, innovation and impact assessment, proposed work description, team capabilities, and a basis of estimate.

Key submission requirements include detailing technical approaches, quantitative metrics comparing proposed technologies to current capabilities, team member qualifications, and a comprehensive cost breakdown. Proposers must identify technical challenges, mitigation strategies, and potential use cases. The opportunity is open to for-profit, non-profit, and academic organizations, seeking solutions to improve Americans' healthspan and health outcomes before disease onset. Proposals should be submitted through https://solutions.arpa-h.gov, with the solicitation number ARPA-H-SOL-24-106, under the Department of Health and Human Services National Institutes of Health.

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APPENDIX A

ARPA-H Mission Office Solution Summary Template

APPENDIX A: MISSION OFFICE SOLUTION SUMMARY TEMPLATE

Solution Summary Cover Page <PRIME ORGANIZATION LOGO (optional)>

Innovative Solutions Opening Title

Solution Summary Title

Submitter Organization

Type of Organization
Choose all that apply:

☐ For-Profit ☐ Non-profit ☐ Academia

Technical Point of Contact (POC)
Name:

Mailing Address:

Telephone:

Email:

Administrative POC
Name:

Mailing Address:

Telephone:

Email:

Estimated Project Duration
____ Months
Total Basis of Estimate
Total: $ ___________________________
Resource Sharing (if applicable)
Gov’t %____ $ _______________________

Performer % ____ $ _______________________

Place(s) of Performance

SUB-AWARDEE AND CONSULTANT

TEAM MEMBERS

(Add rows as necessary)

1. Organization Name:

Technical POC Name:

Organization Type(s):
Choose all that apply:

☐ For-Profit ☐ Non-profit ☐ Academia

2. Organization Name:

Technical POC Name:

Organization Type(s):
Choose all that apply:

☐ For-Profit ☐ Non-profit

3. Organization Name:

Technical POC Name:

Organization Type(s):
Choose all that apply:

☐ For-Profit ☐ Non-profit

4. Organization Name:

Technical POC Name:

Organization Type(s):
Choose all that apply:

☐ For-Profit ☐ Non-profit

NOTE: All Solution Summary submissions must be submitted in English with sans serif font type NO smaller than 11-point and with a readability similar to that of Calibri, Arial, or Avenir Next Pro Light. Smaller sans serif fonts may be used for figures, tables, and charts. Solution Summaries have a limit of six (6) pages. Citations do not count toward the six-page limit. Content recommendations are displayed in blue font and should be deleted before submitting the Solution Summary.

1. CONCEPT SUMMARY

Describe the solution summary concept with minimal jargon and explain how it addresses the ISO interest areas.

2. INNOVATION AND IMPACT

Clearly identify the outcome(s) sought and/or the problem(s) to be solved with the proposed technology concept. Describe how the proposed effort represents an innovative and potentially revolutionary solution to the ISO interest areas. Explain the concept’s potential to be disruptive compared to existing or emerging technologies and how the proposed approach will go far beyond current existing capabilities. To the extent possible, provide quantitative metrics in a table that compares the proposed technology concept to current and emerging technologies which may include:

· A progression of increasingly complex technical challenges.

· State of the art / emerging technology “baseline.”

· Aggressive metrics for each year of the proposed project.

· Summary of specific outcomes from the proposed project or concept.

3. PROPOSED WORK

Describe the final deliverable(s) for the project, key interim milestones, and the overall technical approach used to achieve project objectives. Discuss alternative approaches considered, if any, and why the proposed approach is most appropriate for the project objectives. Describe the background, theory, simulation, modeling, experimental data, or other sound engineering and scientific practices or principles that support the proposed approach. Provide specific examples of supporting data and/or appropriate citations to the scientific and technical literature. Identify adoption challenges to be overcome for the proposed technology to be successful. Describe why the proposed effort is a significant technical challenge and the key technical risks. At a minimum, the solution summary should address:

· Does the approach require one or more entirely new technical developments to succeed?

· How will technical risk be mitigated?

· What use cases, capabilities, or demonstrations will be featured?

4. TEAM ORGANIZATION AND CAPABILITIES

4.1 Indicate the roles and responsibilities of the organizations and key personnel that comprise the Project Team.

4.2 Provide the name, position, and institution of each key team member and describe in 1-2 sentences the skills and experience they bring to the team. Key team members include the individuals who are expected to contribute to the scientific development or execution of the project in a substantive, measurable way.

5. BASIS OF ESTIMATE (BOE)

5.1 Identify a BOE that encompasses all costs and resources for the entire proposed project team. The BOE should include direct labor, materials, supplies, equipment, travel, profit, and any other relevant costs associated with the proposed project.

5.2 The BOE should identify whether resource sharing applies. The table below may be used:

Basis of Estimate (BOE) Amount

Total

Resource Sharing (if applicable)

June 2025 version 1

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