Appendix 1_VAMP CBRN Threat List_19Oct2026.pdf

This document is an appendix to a federal contract solicitation that identifies CBRN (Chemical, Biological, Radiological, Nuclear) threats of concern for the Accelerated Defense Pharmaceuticals (ADP) program under the PME CBRND JPM CBRN Medical portfolio. The appendix does not specify required products, services, response dates, or pricing terms; rather, it serves as reference material defining the threat landscape for which product developers should propose advanced prophylactic platform technologies.

The solicitation (W911SR-26-S-PPFC) requests information from developers regarding design, manufacturing, non-clinical testing, and clinical testing of prophylactic solutions targeting one or more of the prioritized CBRN threats listed. Viral targets include filoviruses (Ebola variants and Marburg), Crimean-Congo hemorrhagic fever, Nipah and Hendra viruses, various encephalitis viruses, hantaviruses, arenaviruses, and select bunyaviruses. Bacterial targets encompass antimicrobial-resistant bacteria, Q fever, plague, anthrax, tularemia, and Burkholderia species. Toxin targets include ricin, T2 mycotoxin, marine toxins, botulinum toxins, and staphylococcal enterotoxin B. Chemical/TICS/TIMS targets cover synthetic chemicals such as fentanyl derivatives, nerve agents, and sulfur mustard. Radiation targets include ionizing, non-ionizing, and nuclear radiation threats. This appendix establishes the threat parameters within which respondents should frame their technical proposals.