US_RS_PRICE_LIST_JAN_23_2017.pdf

U.S. RSII PRICE LIST (USD)

Part Number Product Name / Description US List Price

(USD)

100-259-100 SMRTbell™ Template Prep Kit 1.0 $650 The SMRTbell Template Prep Kit 1.0 contains reagent supplies to perform SMRTbell library preparations of primer-annealed SMRTbell libraries for insert sizes ranging from 500 bp to over 20

kb. Reagent quantities support 10 library preparations.

100-466-100 Barcoded Universal F/R Primers Plate - 96 $156

Barcoded Universal F/R Primers Plate - 96 is a 96-well plate containing barcoded primers. Each well on the plate contains a primer pair consisting of forward and reverse primers having the same barcode. Each barcode is present in only one well for a total of 96 different barcodes on the plate.

Each forward and reverse primer has a universal sequence on the 3’ end. Reagent quantities support a single use of each of the 96 primers pairs in library preparations.

100-514-900 SMRTbell™ Barcoded Adapter Complete Prep Kit - 96 $1,747 The SMRTbell Barcoded Adapter Complete Prep Kit- 96 contains both SMRTbell Barcoded Adapter Prep Kit and Barcoded Adapter Plate - 96. Reagent quantities support 96 complete Barcoded Adapter End Repair and Ligation reactions. Use with SMRTbell Damage Repair Kit to complete template preparation and yield primer-annealed SMRTbell libraries.

100-465-900 SMRTbell™ Damage Repair Kit $936

The SMRTbell Damage Repair Kit contains reagent supplies to perform DNA Damage Repair, Exonuclease III and VII treatments, and primer- annealing of SMRTbell libraries for insert sizes ranging from 500 bp to over 20 kb. Reagent quantities support 10 library preparations. To be used with SMRTbell Barcoded Adapter Complete Prep Kit to generate primer-annealed SMRTbell libraries ready for polymerase binding or to be used independently for extra DNA Damage Repair of template.

100-265-900 AMPure® PB (5ml) $306

AMPure PB magnetic beads are specifically formulated for Pacific Biosciences’ SMRT Sequencing workflow. Beads are used for DNA cleanup and purification during sample extraction and at various stages in the workflow. Reagent quantity supplied at 5 mL volume.

100-372-700 DNA/Polymerase Binding Kit P6 $470 The DNA/Polymerase Binding Kit P6 V2 contains reagent supplies to bind prepared DNA template libraries to the P6-DNA polymerase in preparation for sequencing on the PacBio RS II. Reagent quantities support 24 binding reactions.

100-612-400 DNA Sequencing Reagent 4.0 v2 $400

The DNA Sequencing Kit 4.0 contains a sequencing reagent plate with C4 chemistry and OS Enzyme for single molecule real-time sequencing on the PacBio RS. Reagent quantities support 8 sequencing reactions to be used in conjunction with SMRT® Cell 8Pac(s).

100-676-400 DNA Sequencing Bundle 4.0 v2 (10 Pack) $4,525

The DNA Sequencing Bundle 4.0 contains reagent and disposable supplies for 80 reactions of single molecule real-time sequencing. It contains: 10 DNA Sequencing Reagent plates 4.0, 1 SMRT Cell Oil pack, 1 Sequencing Plate Septa pack, 1 Tube Septa pack.

100-356-500 DNA Internal Control Complex (P6) Support 24 rxn $250 The DNA Internal Control Complex P6 contains a fixed template of 2 kb length, bound to DNA Polymerase P6 for use as an internal sequencing control. Reagent quantities provide spike-in controls for a minimum of 24 samples.

100-209-300 SMRT Oil kit (10 Pack) $260 SMRT® Cell Oil contains 10 reagent tubes for single molecule, real-time DNA sequencing on the PacBio System to be used in conjunction with the DNA Sequencing Kit. Reagent quantities support 10 sequencing runs.

Reagent Kits and SMRT® Cells

Part Number Product Name / Description US List Price

(USD)

100-171-800 SMRT Cell 8Pac (8 Cells) v3 $995 Individual 8Pac containing 8 SMRT Cells V3.

100-530-000 Lambda Lib Complex P6 (2kb) NEW $250 The Lambda Lib Complex P6 (2Kb) contains Lambda library DNA template sheared to a peak size 2Kb bound to Polymerase P6.

100-676-500 MagBead Kit v2 $1,196 The MagBead Kit v2 contains reagent supplies to capture DNA polymerase and template complex for loading onto the PacBio® systems. Kit components include: MagBeads, MagBead Binding Buffer Kit v2 and Wash Buffer kit v2.

100-125-900 MagBeads $1,000 The MagBeads contains 2.88 mL of MagBeads to capture DNA polymerase and template complex for loading onto the PacBio® systems. MagBeads are to be used with MagBead Binding and Wash Buffer Kits.

101-046-400 MagBead Binding Buffer Kit v2 $98

The MagBead Binding Buffer Kit v2 is used with the MagBead Wash Buffer Kit and MagBeads using the Pacific Biosciences Binding Calculator to bind the DNA/Polymerase complex.

101-046-500 MagBead Wash Buffer Kit v2 $98

The MagBead Wash Buffer Kit v2 is used with the MagBead Binding Buffer Kit and MagBeads using the Pacific Biosciences Binding Calculator to bind the DNA/Polymerase complex.

Labware

Part Number Product Name / Description US List Price

(USD)

001-292-541 Tube Septa (20Pac) $57 1 bag of tube septa approved for evaporation control of OS enzyme and SMRT Cell Oil on the PacBio RS II System. Each bag contains 20 tube septa.

100-237-900 Sequencing Plate Septa $208

1 bag of septa mat approved for evaporation and environmental control on the PacBio RS II System of reagents contained in the sequencing plate. Each bag contains 10 septa mats.

000-882-901 Sample Plate Septa $972 1 case of 96-well PCR plate septa approved for evaporation control on the PacBio RS II System. Each case contains 50 plate septa.

100-243-500 Mixing Plate (40 Pac) $728 1 case of 384-well deep well plates approved for reagent and sample mixing on the PacBio RS II System. Each case contains 40 plates.

000-947-365 Mixing Plate (160 Pac) $2,912 1 case of 384-well deep well plates approved for reagent and sample mixing on the PacBio RS II System. Each case contains 160 plates.

001-252-068 Pipet Tips (50 Pac) $3,089 1 case of sterile filter tips approved for robotic liquid handling on the PacBio RS II System. Each case contains 50 racks of 384 tips each.

100-154-200 Pipet tips (10Pac) $744 1 case of sterile filter tips approved for robotic liquid handling on the PacBio RS II System. Each case contains 10 racks of 384 tips each.

000-448-888 Sample Plate (50 plates) $400 One case of 96-well PCR plates contains 50 plates approved for sample placement on the PacBio® systems.

Standard Service Contracts

Part Number Product Name / Description US List Price

(USD)

100-236-400 PacBio Standard Service Contract $84,000 Standard PacBio Service Contract covering all parts and labor required for the repair and maintenance of installed system, subject to Pacific Biosciences Standard Terms and Conditions and applicable Service Contract Data Sheet. Includes RS Insight.

Certain products or portions thereof are manufactured and sold under license from GE Healthcare under patents US 7,056,670, US 7,052,839, US 7,033,762, US 7,041,812, US 7,223,541, US 7,244,566, US 7,560,254, US 7,393,640, and US 7,264,934 and other pending and foreign patent applications. Certain products or portions thereof are manufactured and sold under license from GE Healthcare under its exclusive license from Carnegie Mellon University under U.S. Patent Numbers 6,008,373, 6,130,094, 6,479,303, 6,545,164, 6,673,943 and related patents. Use of such products or portions thereof for purposes other than performing research or research services may require a commercial sublicense from GE Healthcare Biosciences Corp. See applicable product insert for details.

For Research Use Only. Not for use in diagnostic procedures. © Copyright 2010 - 2016, Pacific Biosciences of California, Inc. All rights reserved. Information in this document is subject to change without notice.

Pacific Biosciences assumes no responsibility for any errors or omissions in this document. Certain notices, terms, conditions and/or use restrictions may pertain to your use of Pacific Biosciences products and/or third party products. Please refer to the applicable Pacific Biosciences Terms and Conditions and the applicable license at terms at http://www.pacificbiosciences.com/licenses.html. Pacific Biosciences, the Pacific Biosciences logo, PacBio SMRT, SMRTbell, Iso-Seq, and Sequel are trademarks of Pacific Biosciences in the US and/or certain other countries. All other trademarks are the sole property of their respective owners.

Contact Information Pacific Biosciences 1305 O'Brien Dr. Menlo Park, CA 94025 United States www.pacificbiosciences.com Sales and Support: +1 (877) 920 7222 Email: sales@pacb.com

Quotation and Ordering Information Pacific Biosciences 1305 O'Brien Dr. Menlo Park, CA 94025 United States www.pacificbiosciences.com Sales and Support: +1 (877) 920 7222 Email: orders@pacb.com

US RS