REQUEST FOR QUOTATION

(THIS IS NOT AN ORDER)

THIS RFQ IS IS NOT A SMALL BUSINESS SET-ASIDE

15. DATE OF QUOTATION

16. SIGNER

a. NAME (Type or print)

c. TITLE (Type or print)

b. TELEPHONE

AREA CODE

NUMBER

STANDARD FORM 18 (REV. 6/1995)

Prescribed by GSA-FAR (48 CFR) 53.215-1(a)

AUTHORIZED FOR LOCAL REPRODUCTION

Previous edition not usable

8. TO:

b. COMPANYa. NAME

c. STREET ADDRESS

d. CITY e. STATE f. ZIP CODE

9. DESTINATION

a. NAME OF CONSIGNEE

b. STREET ADDRESS

d. STATE e. ZIP CODE

7. DELIVERY

FOB DESTINATION

OTHER

(See Schedule)

10. PLEASE FURNISH QUOTATIONS TO THE

ISSUING OFFICE IN BLOCK 5a ON OR BEFORE CLOSE OF BUSINESS (Date)

IMPORTANT: This is a request for information and quotations furnished are not offers. If you are unable to quote, please so indicate on this form and return it to the address in Block 5a. This request does not commit the Government to pay any costs incurred in the preparation of the submission of this quotation or to contract for supplies or service. Supplies are of domestic origin unless otherwise indicated by quoter. Any representations and/or certifications attached to this Request for Quotation must be completed by the quoter.

11. SCHEDULE (Include applicable Federal, State and local taxes)

ITEM NUMBER

(a)

SUPPLIES/SERVICES

(b)

QUANTITY

(c)

UNIT

(d)

UNIT PRICE

(e)

AMOUNT

(f)

12. DISCOUNT FOR PROMPT PAYMENT

a. 10 CALENDAR DAYS (%) b. 20 CALENDAR DAYS (%) c. 30 CALENDAR DAYS (%) d. CALENDAR DAYS

NUMBER PERCENTAGE

NOTE: Additional provisions and representations are are not attached.

13. NAME AND ADDRESS OF QUOTER

a. NAME OF QUOTER

b. STREET ADDRESS

c. COUNTY

d. CITY e. STATE f. ZIP CODE

14. SIGNATURE OF PERSON AUTHORIZED TO

SIGN QUOTATION

PAGE OF PAGES

1. REQUEST NUMBER 2. DATE ISSUED 3. REQUISITION/PURCHASE REQUEST NUMBER 4. CERT. FOR NAT. DEF.

UNDER BDSA REG. 2

AND/OR DMS REG. 1

RATING

5a. ISSUED BY 6. DELIVER BY (Date)

NAME TELEPHONE NUMBER

AREA CODE NUMBER

c. CITY

5b. FOR INFORMATION CALL (NO COLLECT CALLS)

National Institutes of Health OD - Office of Logistics and Acquisition Operations 6100 Executive Blvd., Room 6B05 Bethesda, MD 20892-7511

75N98027Q00061

NICHOLAS CAPOBIANCO

+10

000-000000

11/04/2026

11/18/2026 1000 ES

Multiple

PROJECT TITLE: Purchase of One (1)

NVision POLARIS Preclinical

Parahydrogen-Induced Polarizer (PHIP)

System (Brand Name or Equal)

SOLICITATION AUTHORITY: Competitive

Combined Synopsis/Solicitation - Brand

Name or Equal (FAR 12.603, FAR 52.211-6, and FAR Part 13 / Subpart 13.5)

SET-ASIDE STATUS: Unrestricted (Full and

Open Competition) | NAICS: 334516 (1,000

Employees) | PSC: 6640

FAR Solicitation Provisions:

FAR 52.204-7 - System for Award

Management (Nov 2024)

FAR 52.204-16 - Commercial and

Continued...

1 8

CONTINUATION SHEET

REFERENCE NO. OF DOCUMENT BEING CONTINUED PAGES

NAME OF OFFEROR OR CONTRACTOR

SUPPLIES/SERVICES

(B)

UNIT

(D)

UNIT PRICE

(E)

AMOUNT

(F)

OPTIONAL FORM 336 (4-86)

Sponsored by GSA FAR (48 CFR) 53.110

ITEM NO.

(A)

QUANTITY

(C)

NSN 7540-01-152-8067

75N98027Q00061

Government Entity Code Reporting (Aug 2020)

FAR 52.204-24 - Representation Regarding

Certain Telecommunications and Video

Surveillance Services or Equipment (Nov 2021)

FAR 52.211-6 - Brand Name or Equal (Aug 1999)

FAR 52.212-1 - Instructions to

Offerors¿Commercial Products and Commercial

Services (Sep 2023)

FAR 52.212-2 - Evaluation¿Commercial Products and Commercial Services (Nov 2021)

FAR 52.212-3 - Offeror Representations and

Certifications¿Commercial Products and

Commercial Services (May 2024)

FAR 52.225-6 - Trade Agreements Certificate

(Feb 2021)

FAR 52.229-11 - Tax on Certain Foreign

Procurements¿Notice and Representation (Jun

2020)

COMBINED SYNOPSIS / SOLICITATION (COMPETITIVE)

Title: Purchase of One (1) NVision POLARIS Parahydrogen-Induced Polarizer (Brand Name or Equal)

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

(ii) The solicitation number is 75N98027Q00061. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services (Brand Name or Equal in accordance with FAR 52.211-6). The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services (and FAR Subpart 13.5, as applicable).

The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, seeks to award a Firm-Fixed-Price (FFP) Purchase Order/Contract in U.S. Dollars (USD) to the responsible offeror whose proposal represents the best value to the Government.

(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01 and effective date 03/13/2026.

(iv) The associated NAICS code is 334516 (Analytical Laboratory Instrument Manufacturing), and the small business size standard is 1,000 employees.

• This requirement is unrestricted.

(v) Description of Requirement:

Statement of Need and Objectives:

The Chemical Synthesis Center (CSC) at NHLBI serves as a shared NIH resource that provides specialized synthetic chemistry, isotopic labeling, and molecular probe development expertise to investigators across multiple Institutes and Centers. CSC is in need of acquiring the NVision POLARIS Preclinical PHIP-polarizer (Brand Name or Equal) because the instrument will significantly expand CSC's ability to develop and evaluate next-generation molecular imaging probes for NIH investigators. CSC routinely synthesizes isotopically labeled compounds, novel metabolic tracers, and targeted molecular probes;

however, the ability to rapidly assess the hyperpolarization performance and imaging potential of these newly developed agents is currently limited. The POLARIS system will provide a critical capability for screening and optimizing hyperpolarizable ¹³C-labeled compounds during probe development, enabling a direct path from chemical synthesis to biological validation. This capability will benefit a broad range of NIH-supported research programs, including cancer, fibrosis, cardiovascular disease, pulmonary disease, inflammation, and metabolic disorders. By integrating hyperpolarization technology with CSC's existing expertise in synthetic chemistry and isotope labeling, the instrument will establish a shared translational platform that accelerates the development of innovative imaging agents and expands the services CSC can provide to investigators across multiple NIH Institutes and Centers, including:

• NCI (cancer metabolism)

• NHLBI (cardiovascular disease, fibrosis)

• NIDDK (metabolic disorders)

• NINDS (neurodegeneration)

• NIAAA (liver disease)

• NIBIB (imaging technology development)

The instrument provides hyperpolarized MRI using parahydrogen induced polarization (PHIP) on demand at very high levels of polarization.

Product Specifications/Features/Salient Characteristics:

Feature Specification / Salient Characteristic

Polarization >15 % ready for injection

Produced dose 3 options: 0.8 mL volume and 80 mM concentration, 2 mL volume and 80 mM concentration, 1 mL volume and 160 mM concentration (under development)

Process time 3 minutes for dose production, 20 minutes dose-to-dose interval*

Consumables Required

13C-pyruvate precursor**, Rh-catalyst**, Parahydrogen gas in multi-dose standard cylinder***, off-the-shelf reagents***, N2 in standard cylinder or wall outlet***

Dimensions Height 192 cm, Width 87 cm, Depth 80 cm, Weight 400 kg

Site requirements Standard power supply (100 V - 240 V AC, 50 Hz / 60 Hz, 1.5 kW), installation outside of 5 G line, a point vent with 120m3/h or portable filter box provided by NVision, room ventilation ≥ 8 ACH

Transportability Fits in standard elevators, can be wheeled between MRI labs

Fluidic control Integrated fluidic control, no manual manipulation required, automated cleaning after each dose

Certifications Meets relevant US / EU regulations for laboratory equipment

*Including an automated cleaning cycle **Supplied by NVision (or Equal Contractor). Contractor will provide data sheets on request. The ordered Consumables are expected to be used until the expiry dates as communicated on the packaging and labeling, if applicable.

***Customer-provided. Contractor can offer guidance and assistance during the purchasing process, if necessary.

Required Line Items / Scope of Delivery:

• POLARIS Preclinical (or Equal): Preclinical PHIP-polarizer capable of polarizing ¹³C-pyruvate labeled on the first position (Qty: 1)

• Service & Maintenance, Years 1–2: Annual preventive maintenance, replacement of worn parts, cleaning, calibration, safety software updates included for two (2) years (Qty: 1)

• Installation & Commissioning: On-site installation & commissioning (Qty: 1)

• On-site Training: Initial training (up to 3 days) (Qty: 1)

• Filter Box: Accessory for use with POLARIS Preclinical (or Equal) at sites without a point vent (Qty: 1)

• Shipment Charges: Professional packaging, handling, and secure delivery (Delivered Duty Paid [DDP] / F.O.B. Destination) (Qty: 1)

(vi) Delivery Location:

NIH

10 Center Drive Building 10 CRC Room 1W-5940 Bethesda, MD 20892 Point of Contact: Jessica Benjamini

Delivery and Installation Schedule: Delivery of the polarizer system shall be completed within five (5) months After Receipt of Order (ARO), with on-site installation, commissioning, and initial operator training (up to 3 days) completed within six (6) months

ARO (or sooner, coordinated with the NHLBI Technical Point of Contact). The included two

(2) year warranty and annual preventive maintenance period shall commence upon Government acceptance of completed installation and commissioning.

(vii) [Reserved]

(viii) FAR 52.204-7, System for Award Management, applies to this acquisition.

(ix) The provision at FAR 52.212-1, Instructions to Offerors—Commercial Items, and FAR 52.211-6, Brand Name or Equal, apply to this acquisition. Offerors proposing an "equal" product must clearly identify the brand name and model/make offered and provide complete descriptive technical literature demonstrating compliance with all salient characteristics listed in Section (v).

(x) The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.

• (a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation represents the best value to the Government, price and other factors considered.

• (b) Evaluation Factors:

o Price o Technical capability (Ability to meet or exceed all Product Specifications/Features/Salient Characteristics in Section (v)) o Past performance o Delivery schedule

• (c) A written notice of award or acceptance of an offer, issued within the time specified in the offer, shall result in a binding contract without further action by either party. The Government reserves the right to accept any offer before the expiration date.

(xi) FAR 52.212-4, Contract Terms and Conditions—Commercial Items, and FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders— Commercial Products and Commercial Services (including FAR 52.225-5, Trade Agreements), apply to this acquisition.

(xii) Additional contract requirements or terms and conditions, as determined necessary by the Contracting Officer and consistent with customary commercial practices:

1. No Upfront Payment: No advance payments, deposits, or upfront payments upon ordering are permitted. All payments shall be made in arrears (Net 30 days) in accordance with the Prompt Payment Act upon Government receipt, acceptance, and proper invoicing of delivered equipment and completed installation/training services.

2. Firm-Fixed Price in U.S. Dollars (USD): Quotes must be submitted as a Firm-Fixed Price (FFP) in U.S. Dollars (USD). Quotes conditioned upon foreign currency exchange rate fluctuations (e.g., USD/EUR exchange rate limits) or post-award price escalation will not be accepted.

3. Delivered Duty Paid (DDP) / F.O.B. Destination: Delivery terms must be Delivered Duty Paid (DDP) / F.O.B. Destination to 10 Center Drive Building 10 CRC Room 1W- 5940 Bethesda, MD 20892. The Contractor shall act as the Importer of Record and is solely responsible for all shipping, handling, customs clearance, brokerage fees, and any applicable import duties, tariffs, taxes, or levies.

(xiii) The Defense Priorities and Allocations System (DPAS) is not applicable.

(xiv) Submission Requirements:

Responses must include sufficient information to demonstrate the offeror’s capability to provide the required product or service. Quotes shall include, at a minimum:

• Firm-Fixed Unit and Total Price in U.S. Dollars (USD) (with no foreign currency exchange rate contingencies)

• Confirmation of Payment Terms: No upfront payment (Net 30 days upon delivery/acceptance)

• Shipping and handling costs (all-inclusive under Delivered Duty Paid [DDP] terms)

• Delivery timeframe after award

• Delivery terms: Delivered Duty Paid (DDP)

• F.O.B. point: Destination (NIH Building 10 CRC, Rm. 1W-5940, Bethesda, MD 20892)

• Product or catalog numbers (if applicable)

• Product/service description demonstrating compliance with all Salient Characteristics in Section (v)

Additional evaluation considerations may include past performance, warranty, lifecycle cost, maintenance availability, and environmental or energy efficiency. Responses must include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by November 18, 2026 at 10:00 AM EST and must reference solicitation number 75N98027Q00061. Responses may be submitted electronically to nicholas.capobianco@nih.gov.

(xv) Point of Contact:

Nicholas Capobianco Contracting Specialist National Institutes of Health Email: nicholas.capobianco@nih.gov mailto:nicholas.capobianco@nih.gov mailto:nicholas.capobianco@nih.gov

Title