Sol_75N98027Q00048.pdf

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National Institutes of Health OD - Office of Logistics and Acquisition Operations 6100 Executive Blvd., Room 6B05 Bethesda, MD 20892-7511

75N98027Q00048

JOHN JOHNSON

+10

000-000000

11/02/2026

12/14/2026 1400 ES

Multiple

The purpose of this COMBINED

SYNOPSIS/SOLICITATION (Brand Name Only) is to acquire a Multielectrode Array

Instrument.

The following FAR clauses and Provisions are applicable to this award.

FAR 52.204-13 System for Award

Management Maintenance (Oct 2018)

FAR 52.204-18 Commercial and Government

Entity Code Maintenance (Aug 2020)

HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity

Investigations (Dec 2015)

FAR 52.212-4 Contract Terms and

Continued...

1 12

CONTINUATION SHEET

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OPTIONAL FORM 336 (4-86)

Sponsored by GSA FAR (48 CFR) 53.110

ITEM NO.

(A)

QUANTITY

(C)

NSN 7540-01-152-8067

75N98027Q00048

Conditions -In addition to all the applicable commercial Products and Commercial Services

(Nov 2023)

FAR 52.212-5 Contract Terms and Conditions

Required to Implement Statutes or Executive

Orders/Commercial Products and Commercial

Services (Jan 2025)

FAR 52.217-8 Option to Extend Services (Nov

1999)

FAR 52.252-2 CLAUSES INCORPORATED BY REFERENCE

COMBINED SYNOPSIS / SOLICITATION (Brand Name or Equal)

Title: Multielectrode Array Instrument

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

(ii) The solicitation number is 75N98027Q00048/PCA-NIA-12240. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services.

The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold.

The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, seeks to award a firm fixed-price award to the responsible offeror whose proposal represents the best value to the Government.

(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular March 2026.

(iv) The associated NAICS code is 334516, and the small business size standard is “Other Than Small Business”

• This requirement is NOT set aside for Small Business

(v) Description of Requirement:

Purchase Description:

Item Description Cat no Quantity MaxTwo System Lite (US)

* Parallel streaming of 256 channels per well (up to 6 wells simultaneously)

* Includes MaxLab Live Basic, perpetual license

MX2-SYS-LT-US 1

MaxTwo Channel Upgrade License

* Enable parallel streaming of 1020 channels

* Only applicable for MaxTwo System - Lite (MX2-SYS-LT)

MX2-SYS-CHAN 1

Digital Gas Mixing System

* Tokai-Hit GM-3000

* Stand alone digital gas mixing system

* Gas cylinder: 100% CO2

* CO2 concentration: Adjustable between

1.0 to 20.0%

TH-GM-3000 1

MaxTwo 24-Well Plate+ License* License key to enable 24-Well Plate+ feature on MaxTwo* Simultaneous data recording of 24 wells in parallelElectrical stimulation of 24 wells in parallel (requires Stimulation Assay)

MX2-LIC-24W+ 1

Recording PC, * Dell high-performance workstation with MaxLab Live preinstalled, * Intel Core Ultra 9 285K 24- Core Processor* 128 GB DDR5 4400 MHz Memory * 2 × 4 TB NVMe Gen4 SSD Storage * NVIDIA GeForce RTX 5070 12 GB Graphics* Dual 10 GbE Ethernet Ports (Intel X710-T2L) * 27″ UHD (3840 × 2160) IPS Monitor * Two

(2) years warranty

MX-PC-S-US 1

Perfusion System for MaxTwo 6-Well HD-MEA System * Device for simultaneous perfusion of 6-wells compatible with the MaxTwo System

MX2-PRF-SYS 1

MaxLab Live Bundle (MX2) * Includes MaxLab Live ActivityScan and Network Assay, perpetual license * Includes MaxLab Live Batch Analysis and Report Generator Module, perpetual license

MX2-SW-BDL 1

MaxLab Live AxonTracking Assay * Record and automatically identify single neurons * Track axonal arbors Extract conduction velocity of action potentials along multiple axons

MX2-SW-AXON 1

MaxLab Live Stimulation Assay * Enable electrical stimulation for MaxTwo Evoke and extract metrics for stimulus-triggered activity

MX2-SW-ELCSTIM 1

MaxTwo 24-Well-Plate * MX2-S-24W are to be used with a valid subscription only

* Sterilization process: EtO treatment.

With PEDOT coating

MX2-S-24W-PD 5

MaxTwo 6-Well-Plate * MX2-S-6W are to be used with a valid subscription only

MX2-S-6W 5

MaxTwo 24-Well-Plate Starter Package - Subscription, * Including MaxTwo 24- Well Plates subscription for 1 year * Available only when purchased together with MX2-SYS

MX2-24W-START-SBN 1

MaxWell Online Training Program * Lifetime access to on-demand library of training videos, protocols, and product documentation, including future updates

* Personalized guidance throughout program to ensure successful and confident system use. Up to two (2) hours of advanced training sessions with MaxWell Application Experts

TRN-ONLINE 1

MaxTwo System Maintenance Starter Plan - Standard

* Technical maintenance of the MaxTwo System at MaxWell Biosystems

* Valid for 1 year

* Personnel assigned by MaxWell Biosystems will operate all services

MX2-MTN-START-S 1

Shipping Fee * Does not include customs clearance, duties and taxes Incoterms: DAP

SHP 1

(vi) Delivery Location:

NIH/NIA

251 Bayview Blvd STE 100

Baltimore MD 21224

(vii) [Reserved, if needed]

(viii) FAR 52.204-7, System for Award Management, applies to this acquisition.

(ix) The provision at FAR 52.212-1, Instructions to Offerors—Commercial Items, applies to this acquisition. Add any agency-specific instructions as required.

(x) The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.

(a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation represents the best value to the Government, price and other factors considered.

(b) Evaluation Factors:

• Price

• Technical capability

• Past performance

• Delivery schedule

(c) A written notice of award or acceptance of an offer, issued within the time specified in the offer, shall result in a binding contract without further action by either party. The Government reserves the right to accept any offer before the expiration date.

(xi) FAR 52.212-4, Contract Terms and Conditions—Commercial Items, applies to this acquisition.

(xii) Additional contract requirements or terms and conditions, as determined necessary by the Contracting Officer and consistent with customary commercial practices:

(None)

(xiii) The Defense Priorities and Allocations System (DPAS) is (not applicable).

(xiv) Submission Requirements:

Responses must include sufficient information to demonstrate the offeror’s capability to provide the required product or service. Quotes shall include, at a minimum:

• Unit and total price

• Shipping and handling costs

• Delivery timeframe after award

• Delivery terms

• F.O.B. point (destination or origin)

• Product or catalog numbers (if applicable)

• Product/service description

Additional evaluation considerations may include past performance, warranty, lifecycle cost, maintenance availability, and environmental or energy efficiency.

Responses must include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by (December 14, 2026, 2PM, EST) and must reference solicitation number 75N98027Q00048/PCA-NIA-12240 Responses may be submitted electronically to johnsonjr@mail.nih.gov.

(xv) Point of Contact:

John Johnson, Program Specialist, johnsonjr@mail.nih.gov 667-312-5580.

mailto:johnsonjr@mail.nih.gov mailto:johnsonjr@mail.nih.gov

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: This acquisition is necessary to measure the electrical activity of a network of cultured neurons. This instrument is in support of neurodegenerative disease research within the Center for Alzheimer’s Disease and Related Dementias.

2. Background Information and Objective: National Institute on Aging Center for Alzheimer’s Disease and Related Dementias (CARD) is using organotypic slice cultures as a model to investigate biological changes that may contribute to the development of neurodegenerative diseases such as Frontotemporal dementia or Alzheimer's. To assess, glia-induced pathogenic mechanisms, CARD will introduce human-derived iAstrocytes or iMicroglia carrying pathogenic variants in dementia-related genes, either directly, indirectly or via their supernatant to our organotypic cultures. In parallel, CARD will set up a gene editing system to introduce INDELs and study loss-of-function variants associated with dementia in our organotypic cultures. A multielectrode array instrument is required for these studies.

3. Generic Name of Product: Multielectrode Array Instrument

Purchase Description:

Item Description Cat no Quantity MaxTwo System Lite (US)

* Parallel streaming of 256 channels per well (up to 6 wells simultaneously)

* Includes MaxLab Live Basic, perpetual license

MX2-SYS-LT-US 1

MaxTwo Channel Upgrade License

* Enable parallel streaming of 1020 channels

* Only applicable for MaxTwo System - Lite (MX2-SYS-LT)

MX2-SYS-CHAN 1

Digital Gas Mixing System

* Tokai-Hit GM-3000

* Stand alone digital gas mixing system

* Gas cylinder: 100% CO2

* CO2 concentration: Adjustable between 1.0 to 20.0%

TH-GM-3000 1

MaxTwo 24-Well Plate+ License* License key to enable 24- Well Plate+ feature on MaxTwo* Simultaneous data recording of 24 wells in parallelElectrical stimulation of 24 wells in parallel (requires Stimulation Assay)

MX2-LIC-24W+ 1

Recording PC, * Dell high-performance workstation with MaxLab Live preinstalled, * Intel Core Ultra 9 285K 24-Core Processor* 128 GB DDR5 4400 MHz Memory * 2 × 4 TB NVMe Gen4 SSD Storage * NVIDIA GeForce RTX 5070 12 GB Graphics* Dual 10 GbE Ethernet Ports (Intel X710-T2L)

* 27″ UHD (3840 × 2160) IPS Monitor

* Two (2) years warranty

MX-PC-S-US 1

Perfusion System for MaxTwo 6-Well HD-MEA System * Device for simultaneous perfusion of 6-wells compatible with the MaxTwo System

MX2-PRF-SYS 1

MaxLab Live Bundle (MX2) * Includes MaxLab Live ActivityScan and Network Assay, perpetual license * Includes MaxLab Live Batch Analysis and Report Generator Module, perpetual license

MX2-SW-BDL 1

MaxLab Live AxonTracking Assay

* Record and automatically identify single neurons * Track axonal arbors Extract conduction velocity of action potentials along multiple axons

MX2-SW-AXON 1

MaxLab Live Stimulation Assay

* Enable electrical stimulation for MaxTwo Evoke and extract metrics for stimulus-triggered activity

MX2-SW-ELCSTIM 1

MaxTwo 24-Well-Plate * MX2-S-24W are to be used with a valid subscription only * Sterilization process: EtO treatment. With PEDOT coating

MX2-S-24W-PD 5

MaxTwo 6-Well-Plate * MX2-S-6W are to be used with a valid subscription only

MX2-S-6W 5

MaxTwo 24-Well-Plate Starter Package

- Subscription, * Including MaxTwo 24- Well Plates subscription for 1 year

* Available only when purchased together with MX2-SYS

MX2-24W-START-SBN 1

MaxWell Online Training Program

* Lifetime access to on-demand library of training videos, protocols, and product documentation, including future updates * Personalized guidance throughout program to ensure successful and confident system use.

Up to two (2) hours of advanced training sessions with MaxWell Application Experts

TRN-ONLINE 1

MaxTwo System Maintenance Starter Plan - Standard

* Technical maintenance of the MaxTwo System at MaxWell Biosystems

* Valid for 1 year

* Personnel assigned by MaxWell Biosystems will operate all services

MX2-MTN-START-S 1

Shipping Fee * Does not include customs clearance, duties and taxes Incoterms: DAP

SHP 1

4. Salient characteristics All deliverables required under this contract shall be packaged, marked and shipped in accordance with Government specifications. At a minimum, all deliverables shall be marked with the contract number and Contractor name. The Contractor shall guarantee that all required materials shall be delivered in immediate usable and acceptable condition.

High-Density Microelectrode Array Instrument must be able to provide the following features:

1. One button interface to open/close the cover, turn on/off system, and lock the well plate

2. LED system status indicator

3. Footprint no larger than 40cm x 16cm x 12cm

4. Well plate capability for 6- and 24- well plates

5. Heating elements above and below 6- and 24- well plates

6. Temperature control

7. CO2 gas control via gas mixer

8. Coupled with a fully integrated perfusion system

9. Dedicated and integrated assay for axonal tracking that can capture the action potentials propagating along axons.

High-Density Microelectrode Array Plates must be able to provide the following features:

1. Maximum plate dimensions of 127.8 x 85.8 x 16.1mm3 for 6-well plate, and 127.8 x 85.8 x 16.1mm3 for 24-well plate.

2. Maximum inner well diameter of 29.0mm for 6-well plate, and 15.3mm for 24-well plate.

3. Minimum active sensing area of 3.85mm x 2.10mm2 for 6-well plate, and 3.85mm x 2.10mm2 for 24-well plate

4. Minimum total number of 6 x 26,400 electrodes for 6-well plate, and 24 x 26,400 electrodes for 24-well plate.

5. Minimum electrode density of 3,265 electrodes/mm2 for 6-well plate, and 3,265 electrodes/mm2 for 24-well plate.

6. Maximum electrode center to center distance of 17.5μm for 6-well plate, and 17.5μm for 24-well plate.

7. Maximum electrode size of 12.0 x 8.8μm2 for 6-well plate, and 11.5 x 11.5μm2 for 24-well plate

8. Electrode material of platinum black for 6-well plate, and platinum for 24-well plate.

9. Surface topography of < 2.0μm for 6-well plate and < 0.3μm for 6-well plate

10. Minimum sampling rate of 10.0 kHz/channel for 6-well plate and 10.0 kHz/channel for 24-well plate.

11. Minimum number of recording channels of 1,020/well for 6-well plate and

1,020/well for 24-well plate.

12. Simultaneous recordings all 6 wells in parallel for 6 well plate and 6 wells in parallel row by row for 24-well plate.

Perfusion System must be able to provide the following features:

1. Maximum system dimensions of 63 x 39 x 25cm3

2. Well plate capacity of 6 well plate

3. Perfusion rate of 0.04 - 3.00 mL/min

4. Medium volume of 50ml with bottle heater, 100ml – 10L with in-line heater

5. Autoclavable components including cartridges and tubings.

Delivery Date: 3 months after receipt of purchase order

Title