Sol_75N98026Q01108.pdf

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ADDENDA

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75N98026Q01108

See Schedule See Schedule

National Institutes of Health Div. Simplified Acq. Policy & Services, OALM 6701 Rockledge Drive, RK II, 4th floor Bethesda, MD 20817

09/04/2026 1500 ED

ROXANE BURKETT

+1 000 000 0000

OD/OALM

ADM-NHLBI

ROXANE S. BURKETT

334516

1,000

08/27/2026

ADMINISTERED BY:

National Institutes of Health

National, Heart, Lung and Blood

Institute

Bethesda MD 20892-7511 US

Computer Vision Guided Automated Microinjection

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ACCEPTED,

Robot

PUBLIC NOTICE OF PROPOSED ACQUISITION

Office of Acquisitions, Office of Management

National Heart, Lung, and Blood Institute

(FAR Subparts 5.101(a)(2))

1. Announcement/Number: 75N98026Q01108

2. Post Date: 08/27/2026

3. Closing Response Date: 09/04/2026

4. Proposed Award Date: 09/28/2026 – 09/27/2027

5. Project Title: Computer Vision Guided Automated Microinjection Robot

6. Contracting Office: R&D and Professional Services - Division B, OALM Office of the Director, National Institutes of Health, 6701 Rockledge Drive, Rockledge Building 2, Suite 400, Bethesda, Maryland 20892-7902

7. Contact Point/Contracting Officer/Contract Specialist: Roxane Burkett – roxane.burkett@nih.gov

8. Acquisition Authority: This acquisition is being conducted under Federal Acquisition Regulations (FAR) Part 13 – Simplified Acquisition Procedures, and the resultant contract award will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2026-01.

9. North American Classification System (NAICS) Code: 334516

10. Small business size standard: 1,000 employees

11. Classification Code: 6640

12. Set-aside Status: None, this is a single-sole source (including brand-name) non-competitive action.

mailto:roxane.burkett@nih.gov

13. Description:

The Rusan Laboratory conducts research using transgenic Drosophila models to investigate the phenotypic effects and genetic suppressors of mutations associated with human disease. Generation of these models requires microinjection of large numbers of embryos. Conventional embryo microinjection is technically demanding and labor intensive because personnel must prepare, position, identify, target, and inject individual embryos.

The laboratory currently operates a computer-vision-guided automated microinjection robot manufactured by Objective Biotechnology. The system automates significant portions of the embryo-injection process by identifying and targeting embryos using computer vision and performing automated positioning and microinjection. The laboratory requires a second automated microinjection system to increase embryo-processing capacity and support the volume of transgenic animal production required for ongoing research.

The second system will operate alongside the existing Government-owned system. Consistency between the instruments is important so that laboratory personnel can use the same established operating procedures, training, consumables, replacement components, software environment, and experimental workflow across both systems. Increasing automated injection capacity will reduce staff time devoted to repetitive manual microinjection tasks and allow personnel to devote additional time to research activities.

14. Statutory Authority:

This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13—Simplified Acquisition Procedures, Subpart 13.106-1

(b) (1), Soliciting from a single source and is not expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13— Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6—Competition Requirements.

15. Single-sole Source (Including brand-name) Determination:

The determination by the Government to make a single-sole source (including brand-name) award is based upon the market research conducted as prescribed in FAR Part 10—Market Research. Specifically, the results of the market research concluded that the Objective Biotechnology Autoinjector is the only commercially available product identified as capable of fulfilling the Government’s complete minimum requirements for this acquisition.

The NHLBI Rusan Laboratory requires a computer-vision-guided automated microinjection system to increase production capacity for transgenic Drosophila used in ongoing biomedical research. The required system must automatically image and identify Drosophila embryos, use computer vision to target embryos for injection, provide automated positioning, and perform automated microinjection through the intact chorion without requiring each embryo to be precisely aligned manually on a glass coverslip. The laboratory currently owns and operates an Objective Biotechnology Autoinjector, and the second system will operate alongside the existing Government-owned instrument to increase embryo-injection throughput while maintaining a consistent automated workflow.

Market research determined that commercially available microinjection equipment and embryo-manipulation technologies provide capabilities for microinjection generally. However, no other commercially available instrument was identified that is demonstrated to provide the complete combination of automated computer-vision identification and targeting of Drosophila embryos, automated multi-axis positioning, and automated injection through the intact chorion without requiring conventional precise manual alignment of individual embryos. The Objective Biotechnology Autoinjector was identified as providing this complete specialized automated workflow.

Acquisition of a second Objective Biotechnology Autoinjector also preserves consistency with the Government’s existing system, including common operating procedures, software and user interface, injection protocols, consumables, replacement components, training, maintenance procedures, and experimental workflow. This standardization permits the two systems to operate concurrently while avoiding the need to establish, validate, train personnel on, and maintain a separate automated injection workflow.

Accordingly, the Objective Biotechnology Autoinjector is the only commercially available product identified through market research as capable of satisfying the Government’s complete minimum requirement for automated Drosophila embryo microinjection while maintaining compatibility and workflow consistency with the Government’s existing Autoinjector. For these reasons, the Government will proceed with the Objective Biotechnology Autoinjector on a single-source/brand-name basis under FAR 13.106-1(b)(1).

16. Closing Statement:

This notice is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice.

Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include:

unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.”

A determination by the Government not to compete this proposed action based upon responses to this notice is solely within the discretion of the Government.

The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

All responses must be received by September 4, 2026 at 3:00PM EST.

Responses must be submitted via email to the Contracting Officer identified above.

“All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.”

http://www.sam.gov/