Sol_75N98026Q00692.pdf

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National Institutes of Health OD - Office of Logistics and Acquisition Operations 6100 Executive Blvd., Room 6B05 Bethesda, MD 20892-7511

75N98026Q00692

BRITTANY MAY

+10

000-000000

06/23/2026

07/07/2026 1730 ED

Multiple

The purpose of this Competitive Combined

Synopsis/Solicitation is to solicit quotations for One (1) Miniaturized

Head-Mounted Two-Photon Microscope

1 1

07/18

COMPETITIVE COMBINED SYNOPSIS/SOLICITATION

INTRODUCTION

This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

The solicitation number is 75N98026Q00692. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services. The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold.

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under NAICS code 334516 with a Size Standard of 1000.

REGULATORY AUTHORITY

The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2026-01, effective March 13, 2026

• This requirement is unrestricted.

DESCRIPTION OF REQUIREMENT

The Laboratory on Neuronal Circuits and Behaviors (LNCB) at the National Institute of Mental Health (NIMH) records deep brain structures pursuing registration of molecular phenotypes of cells using in- situ hybridization post-two photon imaging using standard head-fixed behaviors with existing microscopes to identify how transcriptional identify of specific cell types relates to behaviorally relevant functional activity. The current single-photon microscopes cannot capture the imaging required due to light scattering associated with single-photon imaging.

The LNCB requires One (1) Miniaturized Head Mounted Two Photon Microscope to be utilized provides insight into brain function during goal-directed motivated behavior in freely moving animals that are presently not possible with existing technologies.

CONTRACTOR REQUIREMENTS

The Miniaturized Head Mounted Two Photon Microscope must meet the following salient characteristics:

• Turn-key system with on-site equipment installation

• Supplefiber bundle for collection of images

• Large field of view (approx. 400 um x 400 um)

• Laser scanning using a micromechanical systems (MEMS) device

• Dichroic Filters for imaging fluorescence in red and green channels

• Two-photon miniscope system that comes with integrated head-fixed device for easier base plating in awake animals

• Mounting adapter

• Headpiece with interchangeable objectives, supple fiber bundle, and hollowcore /

MEMS scanner control conducive to modular modifications in the future

• Interchangeable objective for imaging at different depths, orientations, with cranial windows, prisms, or GRIN lenses

• Electrotunable lens for multiplane two-photon imaging

• A near-infrared, 920 femtosecond pulse laser for two photon imaging

• Fiber coupling with a hollow-core photonic crystal fiber creates a stable system without complicated alignment procedures

• Dummy scope for animal training

• Integrated software to control the laser, detector, the z-scanner, data acquisition and organization

• Technical support in case of troubleshooting

The provision at FAR 52.212-1, Instructions to Offerors—Commercial Items, applies to this acquisition. Add any agency-specific instructions as required.

The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.

The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation represents the best value to the Government, price and other factors considered.

Evaluation Factors:

• Price

• Technical capability

• Past performance

• Delivery schedule

A written notice of award or acceptance of an offer, issued within the time specified in the offer, shall result in a binding contract without further action by either party. The Government reserves the right to accept any offer before the expiration date.

Offerors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Items, with their offer.

FAR 52.212-4, Contract Terms and Conditions—Commercial Items, applies to this acquisition.

FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders—Commercial Items, applies to this acquisition.

Additional contract requirements or terms and conditions, as determined necessary by the Contracting Officer and consistent with customary commercial practices:

None

The Defense Priorities and Allocations System (DPAS) is not applicable.

SUBMISSION REQUIREMENTS

Responses to this synopsis must include sufficient information to demonstrate the offeror’s bona-fide capabilities for fulfilling the required product or service. Responses must include, at a minimum:

• Unit and total price

• Shipping and handling costs

• Delivery period after award

• Delivery terms

• F.O.B. point (destination or origin)

• Product or catalog numbers (if applicable)

• Product/service description

Additional evaluation considerations may include past performance, warranty, lifecycle cost, maintenance availability, and environmental or energy efficiency.

Responses must include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by July 7, 2026 at 5:30 pm, and must reference solicitation number 75N98026Q00692. Responses must be submitted via the SAM.gov webportal. Potential Offerors do not need to register to view a notice; however, in order to submit questions and/or response to this Notice, an account will need to be established.

POINT OF CONTACT:

Brittany May Contract Specialist Brittany.may@nih.gov http://www.sam.gov/

Title