REVISED ATTACHMENT 11 -- Business Proposal Template RFP Amendment 2.xlsx

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Attached to
Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences
Solicitation number
75N96025R00004
Issued by

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Written by GovTribe AI ·

This is a Revised Attachment 11 Business Proposal Template for a federal contract solicitation supporting computational and alternative toxicological methods for the National Institute of Environmental Health Sciences (NIEHS). The document is a comprehensive Excel-based budget template designed for small business offerors, with detailed cost breakdown tabs for various research outlines including information extraction, computational tool development, interlaboratory studies, problem formulation, modeling, database support, meeting support, website maintenance, and training. The template covers a base year and multiple option years, with spaces to input direct labor hours, rates, overhead, fringe benefits, travel costs, and other direct costs for each research activity, allowing bidders to provide a granular financial proposal for the 100% small business set-aside contract.

The solicitation (Solicitation Number 75N96025R00004) is a follow-on requirement to an active contract with Integrated Laboratory Systems, LLC, and is specifically targeted at small businesses with fewer than 1,000 employees. The proposal due date has been extended to December 19, 2025, at 4:30 PM EST, with the document being amended to correct spreadsheet formula inconsistencies. The contract is issued by the NICHD Office of Acquisitions on behalf of NIEHS, with key constraints including a limitation that the small business prime contractor cannot pay more than 50% of the contract value to non-small business subcontractors, ensuring meaningful small business participation in the contract execution.

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Amendment 2 RFP 75N96025R00004 Questions and Answers.pdf PDF
ATTACHMENT 7 Word Version -- Experience Form.docx DOCX document
Amendment 1 RFP 75N96025R00004.pdf PDF
ATTACHMENTS RFP 75N96025R00004 less Attach 11 Excel File.pdf PDF
RFP 75N96025R00004.pdf PDF
ATTACHMENT 11 -- Business Proposal Template RFP 75N96025R00004.xlsx XLSX spreadsheet

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Instruction Tab

Instructions:

Please fill in yellow highlighted cells on each tab. Do not update formulas unless necessary. If formulas are updated, please leave a comment/note on that tab so it will be clearly seen.

Direct Labor fields are for prime contractor only; Subcontracts field is for total/cumulative subcontract costs (inclusive of subcontractor labor, other subcontractor other direct costs, subcontractor indirect costs, etc.).

Itemized cost information and supporting narrative and cost substantiation information for each field should be supplied in the separate Business Proposal document.

Overall Summary

Base Year$ -
Option Year 1$ -
Option Year 2$ -
Option Year 3$ -
Option Year 4$ -
Option Year 5$ -
Option Year 6$ -
Option Year 7$ -
Option Year 8$ -
Option Year 9$ -
Option 2: Optional 6-month Extension$ - 0
Grand Total Base + All Options$ -

Rates

Rates for Base Year
Fringe
Overhead
G&A
Fee
Option Year escalation

Instructions: Insert indirect rates into the applicable yellow boxes. Rates will flow through to applicable tabs.

Admin RO Protcol Outline for Administrative Support/Contract Administration

Base Period per project costs
Direct Laborhoursxrate ($/hr)dollars
Professionalx=$ -
Technicalx=$ -
Total hours and direct labor cost0$ -
with Fringe$ -
with Overhead$ -
Other Direct Costs
Subcontracts
Materials/Supplies
Total Direct/Indirect$ -
Gen & Administrative$ -
Total with G&A$ -
Fee$ -
Total per project (base year 1)$ -
Total Projects per year1
Grand Total$ -

Assumptions

Assumptions for this RO
Use for activities associated with overall contract management and coordination, such as preparing monthly status report, monthly budget summary report, invoice and annual report, planning for attending periodic progress meetings with the Government, maintaining contract and research records, onboarding/offboarding Contractor staff, license fee, etc

Instructions: Insert estimated hours and labor rates into the applicable yellow boxes. Please note any assumptions or formulas changes on this tab in the yellow note box below. Please do this for all tabs.

Sample RO I Sample Research Outline I. Information and data extraction -Mining ICE for chemical information

Base Period per project costsOption 1 - Additional LOE Option -- Base PeriodTotal Base & Option 1
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x$ -=$ -
Technicalx=$ -x$ -=$ -
Total hours and direct labor cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs$ -$ -
Subcontracts
Materials/Supplies$ -$ -
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per project (base year 1)$ -$ -
Total Projects per year103
Grand Total$ -$ -$ -

Assumptions

Sample RO II

Sample Research Outline II. Computational tool development - Pathway-Based Predictive Approaches for Cardiovascular Toxicity Assessment
Base Period per project costsOption 1 -- Additional LOE Option -- Base PeriodTotal Base & Option 1
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x$ -=$ -
Technicalx=$ -x$ -=$ -
Total hours and direct labor cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs
Subcontracts
Materials/Supplies
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per project (base year 1)$ -$ -
Total Projects per year92
Grand Total$ -$ -$ -

Assumptions

Sample RO III-Phase 1 Sample Research Outline III. Interlaboratory study - phase I - iPSC-microglia Protocol development

Base Period per project costsOption 1 -- Additional LOE Option Base PeriodTotal Base & Option 1
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x$ -=$ -
Technicalx=$ -x$ -=$ -
Total hours and direct labor cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs
Subcontracts
Materials/Supplies
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per project (base year 1)$ -$ -
Total Projects per year20
Grand Total$ -$ -$ -

Assumptions

Sample RO III-Phase 2 Sample Research Outline III. Interlaboratory study - phase II - iPSC-microglia Screening test

Base Period per project costsOption 1 -- Additional LOE Option -- Base PeriodTotal Base & Option 1
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x$ -=$ -
Technicalx=$ -x$ -=$ -
Total hours and direct labor cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs
Subcontracts
Materials/Supplies
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per project (base year 1)$ -$ -
Total Projects per year20
Grand Total$ -$ -$ -

Assumptions

Sample RO IV Sample Research Outline IV. Problem formulation - Development of NAM Sets for Evaluation of Emerging Contaminants

Base Period per project costsOption 1 -- Additional LOE Option -- Base PeriodTotal Base & Option 1
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x$ -=$ -
Technicalx=$ -x$ -=$ -
Total hours and direct labor cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs$ -$ -
Subcontracts
Materials/Supplies$ -$ -
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per project (base year 1)$ -$ -
Total Projects per year61
Grand Total$ -$ -$ -

Assumptions

Sample RO V Sample Research Outline V. Modeling - Structural- and Functional Pharmacokinetic-Based Prediction

Base Period per project costsOption 1 -- Additional LOE Option -- Base PeriodTotal Base & Option 1
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x$ -=$ -
Technicalx=$ -x$ -=$ -
Total hours and direct labor cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs
Subcontracts
Materials/Supplies
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per project (base year 1)$ -$ -
Total Projects per year102
Grand Total$ -$ -$ -

Assumptions

Sample RO VI Sample Research Outline VI. Database and Information Support - Development of AI-Powered Liver Fibrosis Prediction

Base Period per project costsOption 1 -- Additional LOE Option -- Base PeriodTotal Base & Option 1
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x$ -=$ -
Technicalx=$ -x$ -=$ -
Total hours and direct labor cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs
Subcontracts
Materials/Supplies
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per project (base year 1)$ -$ -
Total Projects per year21
Grand Total$ -$ -$ -

Assumptions

Sample RO VII Sample Research Outline VII. Meeting Support - Workshop

Base Period per project costsOption 1 -- Additional LOE Option -- Base PeriodTotal Base & Option 1
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x$ -=$ -
Technicalx=$ -x$ -=$ -
Total hours and direct labor cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs
Subcontracts
Materials/Supplies
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per project (base year 1)$ -$ -
Total Projects per year278
Grand Total$ -$ -$ -
Assumptions
Twenty-seven (27) meeting events are expected for base peroid, including Specific Scientific Meetings, Expert Group meeting, Workshops and professional meetings. For costing purposes, the intension is to use the estimated labor hours for Workshop described in this RO to apply to other meeting support. Materials/Supplies for hosting Expert Group meetings and Workshops are expected to be more abundant and captured in "Expert Group" and "Workshop" tabs and not in this tab.

Website maintenance Website Maintenance

Base Period per project costsOption 1 -- Additional LOE Option Base PeriodTotal Base & Option 1
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x$ -=$ -
Technicalx=$ -x$ -=$ -
Total hours and direct labor cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs
Subcontracts
Materials/Supplies
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per project (base year 1)$ -$ -
Total Projects per year31
Grand Total$ -$ -$ -

Assumptions

Training Training support

Base Period per project costsOption 1 -- Additional LOE Option -- Base PeriodTotal Base & Option 1
Direct Laborhoursxrate ($/hr)hoursxrate ($/hr)
Professionalx=$ -x$ -=$ -
Technicalx=$ -x$ -=$ -
Total hours and direct labor cost0$ -0$ -
with Fringe$ -$ -
with Overhead$ -$ -
Other Direct Costs
Subcontracts
Materials/Supplies
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total per project (base year 1)$ -$ -
Total Projects per year21
Grand Total$ -$ -$ -

Assumptions

Expert Group

Contract Other Direct Costs: Meeting material and Participant travel for Exper Group Meetings (4 travel days)
Assumptions: 5 international participants, 10 domestic travelers; meeting held RTP; Government location; 2 day meeting + 2 travel day
Base Period per project costsOption 1 -- Additional LOE Option -- Base PeriodTotal Base & Option 1
UnitsUnitsUnitsUnits
$##$##
1Airfare - Internationalper personXpersonsx=$0per personXpersonsx=$0
2Airfare - Domesticper personXpeopleX=$0per personXpeopleX=$0
3Lodging (Durham, NC Gov't rate)per nightXnightsXpeople$0per nightXnightsXpeople$0
4Per Diem and Incidental expensesper dayXdaysXpeople$0per dayXdaysXpeople$0
Total$0$0
With Gen & Administrative$0$0
With Fee$0$0
TOTAL$0TOTAL$0
Miscelleneous
5Miscelleneous (to cover airport parking, ground transportation, tolls, telephone)per dayXdaysXpeople$0per dayXdaysXpeople$0
6Baggage ($30 each way)Xpeople$0Xpeople$0
7Honorariumper dayXdaysXpeople$0per dayXdaysXpeople$0
8Equipment rental (computers, copier, printer)per dayXdaysX=$0per dayXdaysX=$0
9Transcriptionistper dayXdaysX=$0per dayXdaysX=$0
10Material and Supplies (paper, pens, name tags, etc.)per meetingxNAx=$0per meetingxNAx=$0
Total$0$0
With Gen & Administrative$0$0
With Fee$0$0
TOTAL$0TOTAL$0

MEETING AND PARTICIPANT TRAVEL GRAND TOTAL $0 MEETING AND PARTICIPANT TRAVEL GRAND TOTAL $0

Total Projects per year 2 $0 1 $0 $0

Assumptions

Workshop

Contract Other Direct Costs: Meeting material and Participant travel for Workshop/Symposia/Seminar/Webinar (1 1/2 days) (3 travel days)
For in-person meetings, 12 panel members will be invited
Assumptions: 3 international, 9 domestic travelers; meeting held in DC metro area
Base Period per project costsOption 1 -- Additional LOE Option -- Base PeriodTotal Base & Option 1
UnitsUnitsUnitsUnitsUnitsUnits
$##$##
1Airfare - Internationalper personXpeopleX=$0per personXpeopleX=$0
2Airfare - Domesticper personXpeopleX=$0per personXpeopleX=$0
3Lodging (Washington, DC Gov't rate)per nightXnightsX=$0per nightXnightsX=$0
4Per Diem and Incidental expensesper dayXdaysX=$0per dayXdaysX=$0
Total$0$0
With Gen & Administrative$0$0
With Fee$0$0
TOTAL$0TOTAL$0
MISCELLENEOUS
5Miscelleneous (to cover airport parking, ground transportation, tolls, telephone)per dayXdaysX=$0per dayXdaysX=$0
6BaggageX$0X$0
7Equipment rental (computers, copier, printer)per dayXdaysX=$0per dayXdaysX=$0
8Material and Supplies (paper, pens, name tags, etc.)per meeting$0per meeting$0
9Webcast/teleconference costs for remote viewingper meeting$0per meeting$0
Total$0$0
With Gen & Administrative$0$0
With Fee$0$0
TOTAL$0TOTAL$0

MEETING AND PARTICIPANT TRAVEL GRAND TOTAL $0 MEETING AND PARTICIPANT TRAVEL GRAND TOTAL $0

Total Projects per year 3 $0 1 $0 $0

Assumptions

Contractor Travel

Contract Other Direct Costs: Contractor Travel
Assumptions: Specific Scientific Meeting, Expert Group, and Workshops/Symposium in-person meetings held in DC metro area; locations of SOT and World Congress shall be based on 2023 meetings.
Base Period per trip costsOption 1 -- Additional LOE Option -- Base PeriodTotal Base & Option 1
UnitsUnitsUnitsUnitsUnitsUnits
1Specific Scientific Meeting$##$$##$
Airfareper personXpersons$0per personXpersons$0
Lodgingper personXpersonsXnights$0per personXpersonsXnights$0
Per diemper personXpersonsXday$0per personXpersonsXday$0
Miscelleneous
Miscelleneous (to cover airport parking, ground transportation, tolls, telephone)per dayXpeopleXday$0per dayXpeopleXday$0
BaggageXpeople$0Xpeople$0
Total$0$0
With Gen & Administrative$0$0
With Fee$0$0
ICCVAM MEETING GRAND TOTAL$0ICCVAM MEETING GRAND TOTAL$0
Total Projects per year2$00$0$0
UnitsUnitsUnitsUnitsUnitsUnits
2Expert group Meeting (assume held in Washington, DC)
Airfareper personXpersons$0per personXpersons$0
Lodgingper personXpersonsXnights$0per personXpersonsXnights$0
Per diemper personXpersonsXdays$0per personXpersonsXdays$0
Miscelleneous
Miscelleneous (to cover airport parking, ground transportation, tolls, telephone)per dayXpersonsXdays$0per dayXpersonsXdays$0
BaggageXpersons$0Xpersons$0
Total$0$0
With Gen & Administrative$0$0
With Fee$0$0
EXPERT GROUP MEETING GRAND TOTAL$0EXPERT GROUP MEETING GRAND TOTAL$0
Total Projects per year2$01$0$0
UnitsUnitsUnitsUnitsUnitsUnits
3Workshop/Symposium
Airfareper personXpersons$0per personXpersons$0
Lodgingper personXpersonsXnights$0per personXpersonsXnights$0
Per diemper personXpersonsXdays$0per personXpersonsXdays$0
Miscelleneous
Miscelleneous (to cover airport parking, ground transportation, tolls, telephone)per dayXpeopleXdays$0per dayXpeopleXdays$0
BaggageXpersons$0Xpersons$0
Total$0$0
With Gen & Administrative$0$0
With Fee$0$0
WORKSHOP/SYMPOSIUM MEETING GRAND TOTAL$0WORKSHOP/SYMPOSIUM MEETING GRAND TOTAL$0
Total Projects per year3$01$0$0
UnitsUnitsUnitsUnitsUnitsUnits
4Professional Meetings (Domestic, non-local)(based on cost estimates for the 2023 SOT Meeting)
Airfareper personXpersons$0per personXpersons$0
Lodgingper personXpersonsXnights$0per personXpersonsXnights$0
Per diemper personXpersonsXdays$0per personXpersonsXdays$0
Miscelleneous
Miscelleneous (to cover airport parking, ground transportation, tolls, telephone)per dayXpersonsXdays$0per dayXpersonsXdays$0
BaggageXpersons$0Xpersons$0
Registration (SOT member)per personXpersons$0per personXpersons$0
Total$0$0
With Gen & Administrative$0$0
With Fee$0$0
DOMESTIC PROFESSIONAL MEETING GRAND TOTAL$0DOMESTIC PROFESSIONAL MEETING GRAND TOTAL$0
Total Projects per year3$01$0$0
UnitsUnitsUnitsUnitsUnitsUnits
5Professional Meetings (local)(based on registration fee for 2023 SOT meeting )
Registrationper personXpersons$0per personXpersons$0
Total$0$0
With Gen & Administrative$0$0
With Fee$0$0
LOCAL PROFESSIONAL MEETING GRAND TOTAL$0LOCAL PROFESSIONAL MEETING GRAND TOTAL$0
Total Projects per year2$01$0$0
UnitsUnitsUnitsUnitsUnitsUnits
6Professional Meeting (International) (based on cost estimates for the 2023 World Congress Meeting)
Airfareper personXpersons$0per personXpersons$0
Lodgingper personXpersonsXnights$0per personXpersonsXnights$0
Per diemper personXpersonsXdays$0per personXpersonsXdays$0
Miscelleneous
Miscelleneous (to cover airport parking, ground transportation, tolls, telephone)per dayXpersonsXdays$0per dayXpersonsXdays$0
BaggageXpersons$0Xpersons$0
Registrationper personXpersons$0per personXpersons$0
Total$0$0
With Gen & Administrative$0$0
With Fee$0$0
INTERNATIONAL PROFESSIONAL MEETING GRAND TOTAL$0INTERNATIONAL PROFESSIONAL MEETING GRAND TOTAL$0
Total Projects per year1$00$0$0

Grand Total $0 $0 $0

Assumptions

SUMMARY

All activities (Research Outlines and non-Research Outlines) Cost and Hours per project
Cost Yr 1HrsCost/hr
Admin RO.$ -ERROR:#DIV/0!
RO.I. Information and data extraction -Mining ICE for chemical information$ -ERROR:#DIV/0!
RO.II. Computational tool development - Pathway-Based Predictive Approaches for Cardiovascular Toxicity Assessment$ -ERROR:#DIV/0!
RO.III. Interlaboratory study - phase I - iPSC-microglia Protocol development$ -ERROR:#DIV/0!
RO.III. Interlaboratory study - phase II - iPSC-microglia Screening test$ -ERROR:#DIV/0!
RO.IV. Problem formulation - Development of NAM Sets for Evaluation of Emerging Contaminants$ -ERROR:#DIV/0!
RO.V. Modeling - Structural- and Functional Pharmacokinetic-Based Prediction$ -ERROR:#DIV/0!
RO.VI. Database and Information Support - AI-powered tool development$ -ERROR:#DIV/0!
RO.VII. Meeting Support - Workshop$ -ERROR:#DIV/0!
Website Maintenance$ -ERROR:#DIV/0!
Training Support$ -ERROR:#DIV/0!
NOTE: For Fields C3:C13, include subcontract hours
Cost by activites (per project)
Start Yr 1Start Yr 2Start Yr 3Start Yr 4Start Yr 5Start Yr 6Start Yr 7Start Yr 8Start Yr 9Start Yr 10
Admin RO.$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.I. Information and data extraction -Mining ICE for chemical information$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.II. Computational tool development - Pathway-Based Predictive Approaches for Cardiovascular Toxicity Assessment$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.III. Interlaboratory study - phase I - iPSC-microglia Protocol development$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.III. Interlaboratory study - phase II - iPSC-microglia Screening test$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.IV. Problem formulation - Development of NAM Sets for Evaluation of Emerging Contaminants$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.V. Modeling - Structural- and Functional Pharmacokinetic-Based Prediction$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.VI. Database and Information Support - AI-powered tool development$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.VII. Meeting Support - Workshop$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Website Maintenance$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Training Support$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Total Cost for cumulative number of projects anticipatedCost Summary
Base and Option YearsStart Yr 1Start Yr 2Start Yr 3Start Yr 4Start Yr 5Start Yr 6Start Yr 7Start Yr 8Start Yr 9Start Yr 10TotalBase Total$0
Admin RO.$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -Base + Option 1 Total$0
RO.I. Information and data extraction -Mining ICE for chemical information$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -Base + Option 1 + Option 2 Total$0
RO.II. Computational tool development - Pathway-Based Predictive Approaches for Cardiovascular Toxicity Assessment$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.III. Interlaboratory study - phase I - iPSC-microglia Protocol development$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.III. Interlaboratory study - phase II - iPSC-microglia Screening test$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.IV. Problem formulation - Development of NAM Sets for Evaluation of Emerging Contaminants$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.V. Modeling - Structural- and Functional Pharmacokinetic-Based Prediction$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.VI. Database and Information Support - AI-powered tool development$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.VII. Meeting Support - Workshop$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Website Maintenance$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Training Support$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Contractor Travel Cost$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Other Meeting and Travel Cost (Expert Group and Workshop)$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Base Per Year$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Option 1- Additional Level of Effort OptionsOption 2 -- Option to Extend Services
Options 1 and 2Start Yr 1Start Yr 2Start Yr 3Start Yr 4Start Yr 5Start Yr 6Start Yr 7Start Yr 8Start Yr 9Start Yr 10Total Option 1up to 6 Month Extension
RO.I. Information and data extraction -Mining ICE for chemical information$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.II. Computational tool development - Pathway-Based Predictive Approaches for Cardiovascular Toxicity Assessment$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.III. Interlaboratory study - phase I - iPSC-microglia Protocol development$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.III. Interlaboratory study - phase II - iPSC-microglia Screening test$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.IV. Problem formulation - Development of NAM Sets for Evaluation of Emerging Contaminants$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.V. Modeling - Structural- and Functional Pharmacokinetic-Based Prediction$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.VI. Database and Information Support - AI-powered tool development$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
RO.VII. Meeting Support - Workshop$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Website Maintenance$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Training Support$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Contractor Travel Cost$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Other Meeting and Travel Cost (Expert Group and Workshop)$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -
Option Per Year$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$ -$0
Labor Hours for total number of projects anticipatedLabor Summary
Base and Option YearsStart Yr 1Start Yr 2Start Yr 3Start Yr 4Start Yr 5Start Yr 6Start Yr 7Start Yr 8Start Yr 9Start Yr 10TotalBase Total0
Admin RO.00000000000Base + Option 1 Total0
RO.I. Information and data extraction -Mining ICE for chemical information00000000000Base + Option 1 + Option 2 Total0
RO.II. Computational tool development - Pathway-Based Predictive Approaches for Cardiovascular Toxicity Assessment00000000000
RO.III. Interlaboratory study - phase I - iPSC-microglia Protocol development00000000000
RO.III. Interlaboratory study - phase II - iPSC-microglia Screening test00000000000
RO.IV. Problem formulation - Development of NAM Sets for Evaluation of Emerging Contaminants00000000000
RO.V. Modeling - Structural- and Functional Pharmacokinetic-Based Prediction00000000000
RO.VI. Database and Information Support - AI-powered tool development00000000000
RO.VII. Meeting Support - Workshop00000000000
Website Maintenance00000000000
Training Support00000000000
Base Per Year00000000000
Option 1- Additional Level of Effort OptionsOption 2 -- Option to Extend Services
Options 1 and 2Start Yr 1Start Yr 2Start Yr 3Start Yr 4Start Yr 5Start Yr 6Start Yr 7Start Yr 8Start Yr 9Start Yr 10Totalup to 6 Month Extension
RO.I. Information and data extraction -Mining ICE for chemical information00000000000
RO.II. Computational tool development - Pathway-Based Predictive Approaches for Cardiovascular Toxicity Assessment00000000000
RO.III. Interlaboratory study - phase I - iPSC-microglia Protocol development00000000000
RO.III. Interlaboratory study - phase II - iPSC-microglia Screening test00000000000
RO.IV. Problem formulation - Development of NAM Sets for Evaluation of Emerging Contaminants00000000000
RO.V. Modeling - Structural- and Functional Pharmacokinetic-Based Prediction00000000000
RO.VI. Database and Information Support - AI-powered tool development00000000000
RO.VII. Meeting Support - Workshop00000000000
Website Maintenance00000000000
Training Support00000000000
Option Per Year000000000000

Exec Summary

Base/Option YearsOption 1 -- Additional LOE Options (start year 1)
Direct LaborHoursTotalHoursTotal
Professional0$0.000$0.00
Technical0$0.000$0.00
Total Direct Labor0$ -0$ -
Fringe Benefits$ -$ -
Overhead$ -$ -
Other Direct Costs$ -$ -
Subcontracts$ -$ -
Materials/Supplies$ -$ -
Total Direct/Indirect$ -$ -
Gen & Administrative$ -$ -
Total with G&A$ -$ -
Fee$ -$ -
Total (base year 1)$ -$ -
Base Year$ -$ -
Option Year 1$ -$ -
Option Year 2$ -$ -
Option Year 3$ -$ -
Option Year 4$ -$ -
Option Year 5$ -$ -
Option Year 6$ -$ -
Option Year 7$ -$ -
Option Year 8$ -$ -
Option Year 9$ -$ -
Base/Option 1 Total$ -
Option 1 Total$ -
Option 2$ -
GRAND TOTAL$ -
Notes/Assumptions

Fringe applied to direct labor cost

Overhead applied to Labor plus Fringe

G&A applied to all costs (excluding G&A and fee)

Total Estimate

PeriodEstimated costFixed FeeEstimated Cost Plus Fixed FeeLevel of Effort (LOE)
Base Period$ - 0$ - 0$ - 00
Option Period 1$ - 0$ - 0$ - 00
Option Period 2$ - 0$ - 0$ - 00
Option Period 3$ - 0$ - 0$ - 00
Option Period 4$ - 0$ - 0$ - 00
Option Period 5$ - 0$ - 0$ - 00
Option Period 6$ - 0$ - 0$ - 00
Option Period 7$ - 0$ - 0$ - 00
Option Period 8$ - 0$ - 0$ - 00
Option Period 9$ - 0$ - 0$ - 00
Optional 6-month

Extension IAW

FAR 52.217-8$ - 0$ - 0$ - 00
Period - Optional
LOE IncreaseEstimated costFixed FeeEstimated Cost Plus Fixed FeeLevel of Effort (LOE)
Base Period$ - 0$ - 0$ - 00
Option Period 1$ - 0$ - 0$ - 00
Option Period 2$ - 0$ - 0$ - 00
Option Period 3$ - 0$ - 0$ - 00
Option Period 4$ - 0$ - 0$ - 00
Option Period 5$ - 0$ - 0$ - 00
Option Period 6$ - 0$ - 0$ - 00
Option Period 7$ - 0$ - 0$ - 00
Option Period 8$ - 0$ - 0$ - 00
Option Period 9$ - 0$ - 0$ - 00
Total Base Period and All Options$ - 0$ - 0$ - 00

File details come from the government source that posted it. Updated .