Attachment_E_NIEHS_Level_of_Effort_worksheet.xlsx

This is a Level of Effort cost proposal template for the NIEHS Division of Translational Toxicology (DTT) Chemistry Research solicitation (75N94026R00002). The Excel-based template requires offerors to input direct labor costs, indirect rates, and other direct costs across a base year and up to ten option years, with a standard 3% annual inflation escalation factor. Offerors must populate only designated yellow cells with hourly rates for four labor categories (Senior Research Professional GS-14/15, Research Professional GS-12/13, Technical GS-7/11, and Support Staff GS-5), as well as fringe benefits, indirect costs, General & Administration, and fixed fee percentages. The template automatically calculates total costs by category and contract year through embedded formulas.

The cost proposal is structured into two primary sections: Base Government Cost Estimate for core DTT services and Optional Work Government Cost Estimate for Option 1 additional studies. Offerors must estimate labor hours by task type across 24 defined chemistry-related functional areas including ADMES, Characterization, Formulation, Biosample Analysis, Special Studies, Animal Studies, and Omics activities. Other direct costs categories include materials, supplies, equipment, travel, consultants, and computing communications. The template includes sections for contractor notes and assumptions, and offerors are required to document any formula modifications made to the template. A detailed labor cost breakdown table requires allocation of anticipated hours per year across all four labor categories for both base and optional work tasks.