RFP_75N94022R00001_CSF_Amendment_0002_06-15-2022_0002.pdf

OMB No.: 0990-0115

AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT 1. CONTRACT ID CODE

PAGE

OF PAGES

2. AMENDMENT/MODIFICATION NO.

0 2

3. EFFECTIVE DATE

06/15/2022

4. REQUISITION/PURCHASE

REQ. NO.

N?A

5. PROJECT NO. ((if aapplicable)

6. ISSUED BY CODE 7. ADMINISTERED BY ((If other than Item 5) CODE

National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health and Human Development Contracts Management Branch 6710B Rockledge Drive

BETHESDA MD 20892

8. NAME AND ADDRESS OF CONTRACTOR ((No., street, city, county, State and ZIP Code)

TO ALL POTENTIAL OFFERORS

( ) 9A. AMENDMENT OF SOLICITATION

NO.

RFP 75N94022R00001 X

9B. DATED ((SEE ITEM 11)

06/15/2022

10A. MODIFICATION OF

CONTRACT/ORDER NO.

CODE FACILITY CODE 10B. DATED ((SEE ITEM 13)

11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS

�� The above numbered solicitation is amended as set forth in item 14. The hour and date specified for receipt of Offers is extended.

Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the following methods:

(a) By completing Items 8 and 15, and returning __1___ copy of the amendment in your business proposal; (b) By acknowledging receipt of this amendment on each copy of the offer submitted; or (c) By separate letter or telegram which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by telegram or letter, provided each telegram or letter makes reference to the solicitation and this amendment, and is received prior to the opening hour and date specified.

12. ACCOUNTING AND APPROPRIATION DATA ((if required)

13. THIS ITEM APPLIES ONLY TO MODIFICATIONS OF CONTRACTS/ORDERS,

IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14.

( ) A. THIS CHANGE ORDER IS ISSUED PURSUANT TO FAR 52.243-2. THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE

CONTRACT ORDER NO. IN ITEM 10A.

B.THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as changes in paying office, appropriation date, etc.) SET FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF FAR 43.103(b) and Contract

ARTICLE B.4.

C.THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:

D.OTHER (Specify type of modification and authority)

E. IMPORTANT: Contractor __ is not, X is required to sign this document and return 1 copy in your business proposal to the issuing office.

14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, including solicitation/contract subject matter where feasible.)

PURPOSE: To amend Request for Proposals (RFP) No. 75N94022R00001, entitled “Chemical Synthesis Facility,” to extend the due date for submission of proposals and the deadline for questions. In addition, this Amendment provides responses to questions received regarding this RFP and additional guidance for proposal preparation.

DUE DATE: Thursday, June 23, 2022, 4:00 PM Local Time (Eastern Standard Time [EST]) (Changed).

Questions must be submitted in writing via e-mail by June 17, 2022 (Changed).

Except as provided herein, all terms and conditions of the document referenced in item 9A or 10A, as heretofore changed, remains unchanged and in full force and effect.

15A. NAME AND TITLE OF SIGNER (Type or print)

16A. NAME AND TITLE OF CONTRACTING OFFICER

Alice Pagán Pereira

NICHD Contracts Management Branch, NIH

15B. CONTRACTOR/OFFEROR

BY ______________________________________________

(Signature of person authorized to sign)

15C. DATE

SIGNED

16B. UNITED STATES OF AMERICA

BY ________________________________________

(Signature of Contracting Officer)

16C.DATE

SIGNED Alice M. Pagan

Pereira -S Digitally signed by Alice M.

Pagan Pereira -S Date: 2022.06.15 17:51:52 -04'00'

RFP No. 75N94022R00001 AMENDMENT NO.: 0002 CONTINUATION PAGE Page 2 of 3

A. As a result of this Amendment, the RFP is revised as follows:

1. SECTION A – SOLICITATION/CONTRACT FORM (page 1):

a. Subsection 8 is revised to extend the Proposal Submission Deadline to Thursday, June 23, 2022, 4:00

PM (EST).

b. Subsection 11 is revised to extend the deadline for submission of questions to Friday, June 17, 2022.

B. This Amendment provides answers to questions received regarding this RFP. Please note that individual questions may have been combined or reworded. The responses are provided for information only as guidance to potential offerors and do not supersede any terms of the RFP, and do not revise or become part of this RFP.

1. Question: Do we need to provide a budget for the screening part of the contract, or should the offeror only provide an estimate for GMP Synthesis?

Answer: The offerors shall include a proposed budget that includes both GMP synthesis and small-scale laboratory synthesis. Please see Amendment 1 of this RFP posted on SAM.gov on May 13, 2022, which provided the Government’s estimated effort to assist offerors in the preparation of the proposal.

2. Question: Can the due date of submission of proposals be extended?

Answer: The due date for submitting the proposals is hereby extended to Thursday, June 23, 2022, at 4:00

PM (EST).

C. Additional instructions for minimum and maximum effort budgets over the course of the contract. Please incorporate the tables below in your proposal:

a. Minimum Effort (Government’s estimate hours: 4700 hours)

Period of Performance Estimated Cost ($) Fixed Fee ($) Estimated Cost-Plus Fixed Fee ($)

Base Period: 09/24/2022 – 09/23/2023 Option Period 1: 09/24/2023 – 09/23/2024 Option Period 2: 09/24/2024 - 09/23/2025 Option Period 3: 09/24/2025 - 09/23/2026 Option Period 4: 09/24/2026 - 09/23/2027 Option Period 5: 09/24/2027 - 09/23/2028 Option Period 6: 09/24/2028 - 09/23/2029

TOTALS

b. Maximum Effort (Government’s estimate hours: 9400 hours)

Period of Performance Estimated Cost ($) Fixed Fee ($) Estimated Cost-Plus Fixed Fee ($)

Base Period: 09/24/2022 – 09/23/2023 Option Period 1: 09/24/2023 – 09/23/2024 Option Period 2: 09/24/2024 - 09/23/2025 Option Period 3: 09/24/2025 - 09/23/2026 Option Period 4: 09/24/2026 - 09/23/2027 Option Period 5: 09/24/2027 - 09/23/2028 Option Period 6: 09/24/2028 - 09/23/2029

TOTALS

RFP No. 75N94022R00001

AMENDMENT NO.: 0002

CONTINUATION PAGE

NOTE: See Amendment 1 of the RFP that includes uniform assumptions for the estimate of the small-scale laboratory synthesis and cGMP synthesis.

This information is furnished for the offerors' information only and is not to be considered restrictive for proposal purposes.