36C24E26Q0072_2.docx
DOCX document 27 KB Posted
- Solicitation number
- 36C24E26Q0072
About this file
This is an Amendment to a Request for Quote (RFQ) providing clarifications through Questions and Answers for solicitation 36C24E26Q0072. The Veterans Health Administration Regional Procurement Office East issued this combined synopsis/solicitation as a 100% small business set-aside for multi-omics services supporting a Degenerative Cervical Myelopathy (DCM) study at VA Pittsburgh Healthcare System. The requirement involves analysis services for 40 subject samples, with responses due by July 31, 2026, at 11:59 AM Eastern Time, submitted electronically to Contracting Officer Ms. Millicent Covert at millicent.covert@va.gov.
The amendment clarifies three critical technical specifications: (1) RNA-seq requires 6Gb sequencing depth or 150 million reads per sample; (2) sample collection involves three specialized tubes per subject totaling 120 tubes (40 PAXgene blood tubes for RNA analysis, 40 metabolomics plasma samples, and 40 proteomics plasma samples), with pre-collection separation required rather than post-collection splitting; and (3) proteomics analysis must utilize DIA-based LC-MS/MS technology, not Olink antibody-based panels, clarifying a discrepancy between pricing tables and scope narratives. The NAICS code 541380 (Testing Laboratories and Services) applies with a $19.0M small business employee size standard. This is a firm-fixed price contract awarded under FAR Subpart 12.6 for commercial items. The PSC is AN11 (Health R&D Services; Health Care Services; Basic Research). Quotes must comply with all instructions in the original solicitation and include completed Blocks 15A-15C of the SF30 Amendment form; incomplete submissions will be deemed non-responsive.
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Other files
| File | Type | Posted |
|---|---|---|
| RFQ 36C24E26Q0072 0001_ Amendment SF30.pdf | ||
| 36C24E26Q0072_1.docx | DOCX document |
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Text version
SUBJECT*
Degenerative cervical myelopathy (DCM) multi-omics services
GENERAL INFORMATION
| CONTRACTING OFFICE’S ZIP CODE* |
| 15215-1802 |
| SOLICITATION NUMBER* |
| 36C24E26Q0072 |
| RESPONSE DATE/TIME/ZONE |
| 07-31-2026 11:59 EASTERN TIME, NEW YORK, USA |
| ARCHIVE |
| 30 DAYS AFTER THE RESPONSE DATE |
| RECOVERY ACT FUNDS |
| N |
| SET-ASIDE |
| SBA |
| PRODUCT SERVICE CODE* |
| AN11 |
| NAICS CODE* |
| 541380 |
| CONTRACTING OFFICE ADDRESS |
| Veterans Health Administration |
Regional Procurement Office East Building 32 Suite 1A1111 1010 Delafield Road Pittsburgh PA 15215-1802
POINT OF CONTACT*
Contracting Officer Ms. Millicent Covert millicent.covert@va.gov (Calls shall not be accepted)
PLACE OF PERFORMANCE
ADDRESS
POSTAL CODE
COUNTRY
ADDITIONAL INFORMATION
AGENCY’S URL
URL DESCRIPTION
AGENCY CONTACT’S EMAIL ADDRESS
EMAIL DESCRIPTION
Amendment to a Previous Combined Solicitation Amendment to a Previous Combined Solicitation
DESCRIPTION
| *= Required Field |
| Amendment to a Previous Combined Solicitation |
Page 1 of
Amendment to a Previous Combined Solicitation
AMENDMENT FOR SOLICITATION 36C24E26Q0072
This solicitation is being amended to provide Question and Answers to all offerers/bidders.
QUESTION and ANSWERS Q1: What sequencing depth (Gb) or number of reads per sample (M) is required for the RNA-seq component? If there is no specific target, may we recommend one?
A1: 6Gb, 150 million reads
Q2: What volume of plasma and whole blood will be provided per sample type? Additionally, will 40 separate samples be aliquoted for each project (i.e., dedicated plasma tubes for proteomics and for metabolomics), or will the same plasma sample be sent for both and need to be split at the facility?
A2: Blood will be collected in specialized tubes (one tube is specialized for proteomics and one for metabolomics) – they cannot be collected as one, and then later separated. Each subject will be given three tubes each: PAXgene blood tube will be mailed intact (zero processing), metabolomics blood sample will be centrifuged to collect plasma and placed into its dedicated Eppendorf tube and metabolomics blood sample will be centrifuged to collect plasma and placed into its dedicated Eppendorf tube. There will be 40 subjects for a total of 120 tubes (40 intact blood tubes for RNA, 40 metabolomics plasma samples, and 40 proteomics samples).
Q3: The pricing table (Item 0002) specifies DIA-based LC-MS/MS proteomics, but the Scope/Task 2 narrative specifies "Olink proteomics analysis." These are different technologies (untargeted mass spec vs. targeted antibody-based panels) requiring different vendor capabilities and pricing. Please confirm which platform is required—DIA-MS, Olink, or both. If Olink is required, please specify the panel (e.g., Olink Explore HT, Target 96 Inflammation, etc.).
A3: Thank you for pointing out the discrepancy. DIA-base proteomics is the platform required.
Extension for offers is not granted. Submission deadline remains as no later than Friday, July 31, 2026, at 11:59AM Eastern Time.
IMPORTANT: complete all instructions as noted in “Instructions to Offeror” within original solicitation. Additionally, please complete Blocks 15A – 15C AMENDMENT OF SOLICITATION document. Incomplete submissions will be considered non-responsive.
All offeror quotes for this solicitation must be received electronically through email no later than Friday, July 31, 2026, at 11:59AM Eastern Time. Offers shall be sent by email to Millicent Covert at millicent.covert@va.gov. Reference solicitation number 36C24E26Q0072 within subject line of the email. Any quotes received after the prescribed date/time shall be considered non-responsive and will not be considered for award.
See attached document: RFQ 36C24E26Q0072 0001_ Amendment SF30.
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