08-NON Competitive CSS 75N98026Q01054.docx

NON-COMPETITIVE

COMBINED SYNOPSIS / SOLICITATION

Title: 30 vials of cryopreserved HepaRG cells (Catalog Number: HPRGC10)

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

(ii) The solicitation number is 75N98026Q01054. This solicitation is issued as a Notice of Intent (NOI) for a non-competitive combined synopsis/solicitation to award a contract or purchase order without providing for full and open competition (including brand-name, if applicable).

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold. Additional authority includes 41 U.S.C. 1901 and FAR 6.302-3(a)(2)(ii).

The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a Purchase Order on a non-competitive basis to Life Technologies Corporation, 3175 Staley Road, Grand Island,New York 14072 USA for the purchase of 30 vials of cryopreserved HepaRG cells (Catalog Number: HPRGC10).

(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (insert current circular number and date).

(iv) The associated NAICS code is 6505, Drugs and Biologicals. This requirement is not set aside for small business.

(v) Description of Requirement:

The National Institute of Environmental Health Sciences (NIEHS) / Division of Translational Toxicology (DTT) / The Mechanistic Toxicology Branch (MMB) needs to purchase 30 vials of cryopreserved HepaRG cells (Catalog Number: HPRGC10) to explore NAM-based approaches for modeling toxicity-induced liver injury in humans with 3D microphysiological systems.

HepaRG are immortalized progenitor cells with established functionality to model aspects of human liver cell and tissue physiology far superior to conventional liver cell lines. These cells have also been shown to model liver fibrosis in response to toxic exposures when combined with stellate cells and monocytes. Thus, they represent an ideal cell system for optimizing assay and imaging conditions prior to initiating work with primary human liver cells from individual donor tissues.

Requirements:

Catalog Number: HPRGC10; HEPARG CELLS CRYOPRESERVED 10 MILLION RECOVERABLE CELLS

(vi) Delivery Location:

NIH/NIEHS

111 TW Alexander Drive Research Triangle Park, NC 27709

(vii) [Reserved, if needed]

(viii) FAR 52.204-7, System for Award Management, applies to this acquisition.

(ix) The provision at FAR 52.212-1, Instructions to Offerors—Commercial Items, applies to this acquisition. Add any additional instructions as required.

(x) The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.

(a) A written notice of award or acceptance of an offer, issued to the successful offeror within the time specified in the offer, shall result in a binding contract without further action by either party.

The Government reserves the right to accept any offer (or part of an offer) before the expiration date, whether or not discussions are conducted, unless a written notice of withdrawal is received prior to award. Add additional evaluation criteria as required.

(xi) FAR 52.212-4, Contract Terms and Conditions—Commercial Items, applies to this acquisition.

(xii) Additional contract requirements or terms and conditions, as determined necessary by the Contracting Officer and consistent with customary commercial practices: None.

(xiii) The Defense Priorities and Allocations System (DPAS) is not applicable to this requirement.

(xiv) Submission Requirements:

Responses must include sufficient information to demonstrate the respondent’s capability to provide the required product or service. Price quotations shall include, at a minimum: unit price, list price, shipping and handling costs, delivery timeframe after award, delivery terms, prompt payment discount terms, F.O.B. point (destination or origin), product or catalog numbers, product descriptions, and any other relevant information.

Evaluation factors may include, but are not limited to: past performance, technical capability, special features, trade-in considerations, expected lifecycle, warranty, maintenance availability, and environmental or energy efficiency considerations.

Respondents claiming to be manufacturers or authorized resellers of a specified brand-name product must provide:

(a) Product, catalog, model, and/or part number(s);

(b) Product description;

(c) Documentation demonstrating that the offered item meets all required salient characteristics;

(d) Quantity;

(e) Estimated price or cost;

(f) Shipping, handling, and/or installation charges; and

(g) Delivery timeframe after receipt of order.

Responses must also include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by September 1, 2026 and must reference solicitation number 75N98026Q01054. Responses may be submitted electronically to wagstaff@nih.gov.

(xv) Point of Contact:

Francisca Wagstaff at wagstaff@nih.gov