Pharmacokinetic and Pharmacology Evaluations for Cancer Patients

Ended Master IDIQ Awarded

Federal agency
Awardees
5
Task orders
14
Obligated
$1,180,979

Vehicle facts

Opportunity
  • N02CM6700011 Solicitation number
Agency
Combined task order value
  • $1,180,979 Current, with exercised options
  • $1,452,665 Potential, with all options
Last date to order 100% complete
Shared ceiling 12% used
$9,900,000.00

IDV award and task order details come from SAM.gov/FPDS.

About this vehicle

The National Institutes of Health established this Master IDIQ for preclinical pharmacokinetic and pharmacology evaluations of cancer-therapy agents on July 1, 2016, with a shared ceiling of $9.9 million, but ordering closed on June 30, 2021 — this vehicle is no longer accepting new task orders.

Fourteen task orders were issued under the vehicle, with the most recent award on April 16, 2021. The National Cancer Institute (within NIH) placed all 14 orders. Activity declined sharply after the initial years: 2016–2017 saw nine orders, but only one order was placed in 2018, three in 2019, and one in 2021. The combined potential value across all task orders is $1.5 million, with $1.2 million obligated (81% of potential).

Awarded work centers on preclinical pharmacokinetic studies in animal models and analytical support for drug-candidate assessment. Task orders include pharmacokinetic and bioavailability studies in mice and rats (using NSG mouse models), plasma and urine bioanalysis for anticancer compounds, and formulation testing for early-stage pharmacokinetic assessments. Most orders are firm-fixed-price or cost-no-fee arrangements with performance periods ranging from one to five years. Representative task-order values range from roughly $27,000 to $218,000 in ceiling value.

Competition is highly concentrated. University of Pittsburgh holds 50% of combined potential value across seven orders ($851 thousand). Mayo Clinic accounts for 39% across four orders ($592 thousand). Southern Research Institute, Sri International, and IIT Research Institute collectively represent the remaining 11% with one order each. All orders are unrestricted (no set-aside designations).

This vehicle is inactive and unsuitable for new business development. The ordering window closed over five years ago, and no recompete or successor vehicle is indicated in the source material.

Description

Preclinical Pharmacokinetic and Pharmacology Evaluations of Agents Being Developed for Cancer Patients

IDV awards

Latest task orders

Task order Awardee Awarding agency Obligated Last action
Torfp g: to#6 "analytical support and PK sample analysis for preclinical… 75N91019F00130 University Of Pittsburgh - Of The Commonwealth System Of Higher Education NCI $59,335
Pharmacokinetic studies with selected anticancer compounds in NSG mice period… 75N91019F00129 University Of Pittsburgh - Of The Commonwealth System Of Higher Education NCI $208,940
Torfp h - title: "pharmacokinetic studies with selected anticancer compounds in… 75N91019F00129 Mayo Clinic NCI $174,696
Next NX232-107-158-006 to#3 milestone 3 (base) - PK & bioavail stud… HHSN26100003 Mayo Clinic NCI $167,150
Title: pharmacokinetic and bioavailability studies and analytical support… HHSN26100002 Mayo Clinic NCI $136,518
Special studies/analysis- chemical/biological HHSN26100003 University Of Pittsburgh - Of The Commonwealth System Of Higher Education NCI $17,757
Title: "determination of 5-fluoro-2'-deoxycytidine (fdcyd), selected downstream… HHSN26100004 University Of Pittsburgh - Of The Commonwealth System Of Higher Education NCI $27,605
Title: determination of LMP744 (NSC 706744) levels in human plasma and urine… HHSN26100002 University Of Pittsburgh - Of The Commonwealth System Of Higher Education NCI $274,027
Title: pharmacokinetic and oral bioavailability studies in rats. Period of… 75N91021F00001 University Of Pittsburgh - Of The Commonwealth System Of Higher Education NCI $103,177
Kick-off meeting preclinical pharmacokinetic & pharmacology evaluations of… HHSN26100001 University Of Pittsburgh - Of The Commonwealth System Of Higher Education NCI $685
Kick off meeting, pharmacokinetic & pharmacological evaluations of agents being… HHSN26100001 Southern Research Institute NCI $5,752
Kick off meeting, preclinical pharmacokinetic & pharmacological evaluations… HHSN26100001 Sri International NCI $2,723
Kick off meeting, preclinical pharmacokinetic & pharmacological evaluations… HHSN26100001 Mayo Clinic NCI $1,603
Kick off meeting, preclinical pharmacokinetic & pharmacology evaluations of… HHSN26100001 IIT Research Institute NCI $1,010
Show all 14

Top awardees by obligations

Rank Awardee Obligated Share
1 University Of Pittsburgh - Of The Commonwealth System Of Higher Education $691,527 59%
2 Mayo Clinic $479,967 41%
3 Southern Research Institute Minimum guarantee only $5,752 <1%
4 Sri International Minimum guarantee only $2,723 <1%
5 IIT Research Institute Minimum guarantee only $1,010 <1%

"Minimum guarantee only" marks awardees whose obligations here are just the minimum order their contract guarantees.

Top funding agencies by obligations

Rank Funding agency Obligated Share
1 Department of Health and Human Services $1,180,979 100%

Obligations by fiscal year

Fiscal year Obligated
FY2026 -$8,348
FY2023 $4,479
FY2022 $170,717
FY2021 $253,236
FY2020 $128,193
FY2019 $206,573
FY2018 $75,565
FY2017 $338,475
FY2016 $12,088

Quick answers

What is the Pharmacokinetic and Pharmacology Evaluations for Cancer Patients contract vehicle?

Pharmacokinetic and Pharmacology Evaluations for Cancer Patients is an indefinite delivery, indefinite quantity (IDIQ) contract vehicle run by National Institutes of Health (Department of Health and Human Services), awarded on July 1, 2016.

Which companies hold Pharmacokinetic and Pharmacology Evaluations for Cancer Patients?

5 companies hold Pharmacokinetic and Pharmacology Evaluations for Cancer Patients's IDV awards, one each. The latest went to Sri International on July 1, 2016. The awardees whose task orders obligated the most are University Of Pittsburgh - Of The Commonwealth System Of Higher Education, Mayo Clinic and Southern Research Institute.

How much has been spent through Pharmacokinetic and Pharmacology Evaluations for Cancer Patients?

14 task orders have been placed under Pharmacokinetic and Pharmacology Evaluations for Cancer Patients, obligating $1,180,979.

What is the shared ceiling of Pharmacokinetic and Pharmacology Evaluations for Cancer Patients?

Pharmacokinetic and Pharmacology Evaluations for Cancer Patients's shared ceiling is $9,900,000; its task orders have used 12% of it.

Which agencies use Pharmacokinetic and Pharmacology Evaluations for Cancer Patients the most?

The departments whose task orders under Pharmacokinetic and Pharmacology Evaluations for Cancer Patients obligated the most are Department of Health and Human Services ($1,180,979).

On GovTribe

See this vehicle's full record

  • Every IDV award and task order
  • Funding by agency, awardee, NAICS and set-aside
  • Teaming partners on this vehicle
  • Ask GovTribe AI about this vehicle