CRO Support for NCATS In Vitro and In Vivo Toxicology Studies

Award Date 4/20/2017
Last Date To Order 4/20/2022
Shared Ceiling $20M
Contract Type
Master IDIQ
Predecessor
Not listed
Successors

The National Center for Advancing Translational Sciences (NCATS) Master Indefinite Delivery/Indefinite Quantity (IDIQ) contract for Contract Research Organization (CRO) Support for In Vitro and In Vivo Toxicology Studies provides preclinical drug development and safety assessment services. The contract vehicle enables NCATS to procure non-clinical safety evaluations and toxicology studies across various therapeutic areas, supporting the advancement of potential drug candidates through early-stage development. The vehicle specifically focuses on conducting exploratory and genetic toxicology testing, as well as in-vivo toxicity assessments for small and large molecular compounds.

The task orders under this IDIQ consistently involve non-clinical safety assessments for drug candidates targeting diverse medical conditions, including neuropathic pain, hearing loss, gene therapies, multiple sclerosis, and rare diseases. Typical task orders range from $268,799 to $6,469,946, with performance periods spanning approximately 18-24 months. Frequent prime contractors include IIT Research Institute, Battelle Memorial Institute, Sri International, and Lovelace Biomedical Research Institute, all of which are non-profit research organizations. The contracts are consistently structured as cost-plus-fixed-fee, with no set-aside designations, and performance locations primarily in research facilities located in cities like Chicago, Columbus, and West Menlo Park. The funding consistently originates from the Department of Health and Human Services' National Institutes of Health, specifically the National Center for Advancing Translational Sciences.

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