Non-clinical safety assessment of gene therapy (pcca, mmab, DOK7 and colq) to support platform gene therapy for congenital myasthenic diseases (DOK7, colq) and acidemia (pcca, mmab)

Active Awarded Last action

Contract number
75N95020F00001
Awardee
Awarding agency
Obligated
$5,298,497

Award facts

Opportunity
Contract value 65% obligated
  • $5,298,497.16 Current, with exercised options
  • $8,098,466.16 Potential, with all options
Completion date 91% complete
Current and potential, with all options
Set-aside
No set-aside
Competition
Full and Open Competition · 3 offers Multiple Award, Fair Opportunity
Pricing
Cost Plus Fixed Fee
Place of performance
Albuquerque, NM 87108, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Supplemental Agreement for work within scope P00007 $1,282,991
Exercise an Option P00006 $1,745,514
Supplemental Agreement for work within scope P00005 $0
Supplemental Agreement for work within scope P00004 $0
Supplemental Agreement for work within scope P00003 $0
Supplemental Agreement for work within scope P00002 $0
Change Order P00001 $0
Original award $2,269,992

About this award

The National Institute on Drug Abuse issued a delivery order to Lovelace Biomedical Research Institute on September 25, 2020, with a ceiling value of $8,098,466.16 under the CRO Support for NCATS In Vitro and In Vivo Toxicology Studies IDIQ. The order is priced on a cost-plus-fixed-fee basis and covers non-clinical safety assessment of gene therapy platforms (PCCA, MMAB, DOK7, and COLQ) to support treatment of congenital myasthenic diseases and acidemia, with in vitro and in vivo toxicology studies.

Place of performance is Albuquerque, NM. Performance is scheduled through May 31, 2027.

Service Contract Inventory reporting shows minimal labor deployment in the order's active fiscal years. FY2024 invoiced $13,000 across 0.1 FTEs and 150 contractor hours at a derived rate of $87.49 per hour. FY2021 reported 68 contractor hours at $77.42 per hour on $5,000 invoiced. The prime self-performed all reported hours with no subcontractor engagement.

Quick answers

Who was awarded contract 75N95020F00001?

75N95020F00001 was awarded to Lovelace Biomedical Research Institute by National Institute on Drug Abuse (National Institutes of Health) on September 25, 2020.

How much is contract 75N95020F00001 worth?

The government has obligated $5,298,497 on 75N95020F00001. Its potential value, with all options, is $8,098,466.

Is contract 75N95020F00001 an order under another contract?

Yes. 75N95020F00001 is a delivery order under HHSN271201700017I, an indefinite delivery contract, on CRO Support for NCATS In Vitro and In Vivo Toxicology Studies.

Was contract 75N95020F00001 competed?

The extent of competition for 75N95020F00001 was full and open competition. The government received 3 offers.

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