BARDA Chem and RadNuc Animal Model 2015-2020

The BARDA Chem and RadNuc Animal Model 2015-2020 is an Indefinite Delivery/Indefinite Quantity (IDIQ) contract vehicle established by the Biomedical Advanced Research and Development Authority (BARDA) to support the development of animal models for medical countermeasures against chemical, radiological, and nuclear threats. The primary objective of this contract vehicle is to facilitate research, testing, and development of animal models that can effectively simulate human disease conditions and evaluate potential medical countermeasures for chemical warfare agents, radiological exposure, and related threats. The solicitation seeks Good Laboratory Practice (GLP) laboratories capable of establishing and utilizing animal models that closely mimic human physiological responses to various hazardous agents.

Task orders under this IDIQ have consistently been awarded to research institutions and nonprofit organizations, including Battelle Memorial Institute, University of Maryland, University of Illinois, Lovelace Biomedical Research Institute, and TNO. The typical task order values range from approximately $400,000 to $11.8 million, with performance periods generally spanning 2-4 years. The primary funding agency is the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the Department of Health and Human Services. None of the task orders utilized set-aside designations, and the contractors frequently perform work at their own research facilities. The task orders cover diverse scopes such as developing animal models for chlorine gas exposure, synthetic opioid-induced respiratory depression, sulfur mustard toxicities, and acute radiation syndrome, demonstrating the vehicle's broad focus on medical countermeasure research and development.