Parent award - medicinal chemistry support program for therapeutic development

Active Indefinite Delivery Contract Awarded Last action

Contract number
HHSN271201800001I
Awardee
Awarding agency
Task orders
26 $42,165,989 obligated

Award facts

Opportunity
Combined order value
  • $43,622,406 Current, with exercised options
  • $62,126,371 Potential, with all options
Last date to order 86% complete
IDV ceiling 61% used
$69,645,159.00
Award type
Single award
Who can order
Only the awarding agency
Funding agency
National Institute of Neurological Disorders and Stroke National Institutes of Health, Department of Health and Human Services
Set-aside
No set-aside
Competition
Full and Open Competition · 4 offers Negotiated Proposal / Quote
Pricing
Cost Plus Fixed Fee

Award details come from SAM.gov/FPDS.

About this IDV

The National Institute of Neurological Disorders and Stroke awarded a single-award indefinite-delivery contract to Curia Global Inc. (doing business as Amri) on March 16, 2018, with a ceiling value of $69,645,159.00 and an ultimate completion date of March 15, 2028. Work is performed in Albany, New York.

The contract supports the Medicinal Chemistry Support Program for Therapeutic Development, providing end-to-end pharmaceutical research and development services spanning exploratory chemistry, hit-to-lead chemistry, lead optimization chemistry, absorption/distribution/metabolism/excretion (ADME) testing, process chemistry, scale-up synthesis, good manufacturing practices (GMP) production, and stability testing across therapeutic areas including neurology, infectious diseases, substance abuse, and translational sciences. The IDIQ covers multiple performance areas, including tech transfer, storage, handling, distribution, and IT security for an existing compound repository.

All delivery orders issued under this IDIQ carry cost-plus-fixed-fee pricing except the initial task order (firm fixed price). Recent delivery orders include the Martin (Nuvonuro) program for hit-to-lead chemistry and ADME testing; Tsukamoto (Johns Hopkins University) for lead optimization chemistry; Spigelman (UCLA) for exploratory chemistry; Aldrich (University of Florida) for exploratory chemistry and ADME testing; Grace (University of Texas MD Anderson Cancer Center) for hit-to-lead chemistry; Lu (Texas A&M University) for hit-to-lead chemistry; Ganesh (Emory University) for hit-to-lead chemistry; Shamloo (Stanford University) for exploratory chemistry; Al-Ali (University of Miami) for exploratory chemistry; Trushina (National Institute of Mental Health) for Alzheimer's disease exploratory chemistry; and Florio (Anagin) for stroke-focused exploratory chemistry. These orders draw from multiple NIH institutes including the National Institute on Drug Abuse, National Institute on Aging, and National Institute of Mental Health, in addition to NINDS.

Task orders

Task order Ordering agency Obligated Awarded
Exploratory chemistry. Medicinal chemistry support program for therapeutic development (mcsp). POP: september 21… 75N98026F00003 Office of Logisitics and Acquisition Operations (NIH) $669,175
Exploratory chemistry and HIT-to-lead chemistry option. Medicinal chemistry support program for therapeutic development… 75N98026F00001 Office of Logisitics and Acquisition Operations (NIH) $2,138,209
Exploratory chemistry. Medicinal chemistry support program for therapeutic development (mcsp). POP: september 21… 75N98026F00002 Office of Logisitics and Acquisition Operations (NIH) $692,173
75N95025F00001 National Institute on Drug Abuse (NIH) $922,304
Tsukamoto (johns hopkins university) mcsp - lead optimization chemistry 75N95023F00004 National Institute on Drug Abuse (NIH) $1,474,682
Spigelman (ucla) - mcsp- exploratory chemistry (EC) 75N95023F00003 National Institute on Drug Abuse (NIH) $1,981,927
Martin (nuvonuro)-HIT to lead chemistry-admet only- mcsp-heal 75N95023F00002 National Institute on Drug Abuse (NIH) $256,491
Medicinal chemistry services to support project "aldrich (univ. Of florida) - exploratory chemistry-admet only - mcsp" 75N95023F00001 National Institute on Drug Abuse (NIH) $404,158
HIT to lead chemistry under performance area 2 of ID/IQ contract no. HHSN271201800001I 75N95022F00007 National Institute on Drug Abuse (NIH) $1,796,372
HIT to lead chemistry under performance area 2 of ID/IQ contract no. HHSN271201800001I 75N95022F00005 National Institute on Drug Abuse (NIH) $1,471,823
Ganesh (emory university) - mcsp - HIT to lead chemistry 75N95022F00004 National Institute on Drug Abuse (NIH) $2,873,043
Shamloo (standford university) - mcsp-exploratory chemistry (EC) 75N95022F00003 National Institute on Drug Abuse (NIH) $3,360,769
AL-ALI (university of miami, school of medicine) - mcsp - exploratory chemistry (EC) 75N95022F00002 National Institute on Drug Abuse (NIH) $3,173,499
Mcsp torfp no. NIH-ninds-21-02: trushina (medchem) - base exploratory chemistry (alzheimer's disease) 75N95021F00001 National Institute on Drug Abuse (NIH) $607,397
Mcsp torfp no. NIH-ninds-21-01: florio (anagin) - base EC (stroke) 75N95021F00022 National Institute on Drug Abuse (NIH) $3,420,025
Mcsp torfp no. NIH-ninds-20-03: katritch (USC) - base EC (pain) 75N95020F00003 National Institute on Drug Abuse (NIH) $3,167,871
Mcsp torfp no. NIH-ninds-20-04: childers - base EC [substance use disorder (cocaine)] 75N95020F00004 National Institute on Drug Abuse (NIH) $631,254
Mcsp torfp no. NIH-ninds-20-02: mouradian/disney - base EC (parkinson's) 75N95020F00002 National Institute on Drug Abuse (NIH) $1,392,674
NIH blueprint neurotherapeutics network (BPN) medicinal chemistry support program (mcsp) 75N95020F00001 National Institute on Drug Abuse (NIH) $251,981
Mulcahy exploratory chemistry 75N95019F00089 National Institute on Drug Abuse (NIH) $1,804,475
Mcnamara exploratory chemistry 75N95019F00088 National Institute on Drug Abuse (NIH) $2,869,424
Albany molecular research, INC(amri)[19-002417]mcsp task order XU project - exploratory chemistry POP: TBD 75N95019F00064 National Institute on Drug Abuse (NIH) $555,782
Task order no. 4 - rosenzweig-lipson - mscp - LO 75N95018F00004 National Institute on Drug Abuse (NIH) $1,376,050
Task order no. 3 miller LO - medicinal chemistry support program for therapeutic development 75N95018F00003 National Institute on Drug Abuse (NIH) $1,297,588
Task order no. 2 - "van leyen mcsp-EC" 75N95018F00002 National Institute on Drug Abuse (NIH) $3,403,139
Task order no. 0001 - medicinal chemistry support program for therapeutic development (mcsp HHSN27100001 National Institute on Drug Abuse (NIH) $173,705
Show all 26

Transactions

Action Obligated Date
Other Administrative Action P00008 $0
Other Administrative Action P00007 · Medicinal chemistry support program for therapeutic development. POP: march 16, 2018 to march 15, 2028. $0
Other Administrative Action P00006 · Medicinal chemistry support program for therapeutic development $0
Supplemental Agreement for work within scope P00005 · Further incorporoate e.o .14042 ensuring adequate covid safety protocols for federal contractors $0
Other Administrative Action P00004 $0
Supplemental Agreement for work within scope P00003 · Modify terms and conditions of parent contract: medicinal chemistry support program for therapeutic development $0
Change Order P00002 $0
Other Administrative Action P00001 $0
Original award $0

Quick answers

Who was awarded contract HHSN271201800001I?

HHSN271201800001I was awarded to Curia Global Inc. by National Institute on Drug Abuse (National Institutes of Health) on March 16, 2018.

How much is contract HHSN271201800001I worth?

Orders under HHSN271201800001I have obligated $42,165,989. Their combined current value, with exercised options, is $43,622,406. Their combined potential value, with all options, is $62,126,371. HHSN271201800001I's own ceiling is $69,645,159.

How many orders have been placed under contract HHSN271201800001I?

26 orders have been placed under HHSN271201800001I, the latest on September 21, 2026.

Which agency awarded contract HHSN271201800001I?

National Institute on Drug Abuse (National Institutes of Health) awarded HHSN271201800001I, with funding from National Institute of Neurological Disorders and Stroke (National Institutes of Health).

Who can order from contract HHSN271201800001I?

HHSN271201800001I is a single award indefinite delivery contract. Only the awarding agency can place orders on it.

Was contract HHSN271201800001I competed?

The extent of competition for HHSN271201800001I was full and open competition. The government received 4 offers.

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