Project Grant W81XWH2210556

This $181,772 project grant from the National Heart, Lung and Blood Institute will support research into coagulopathy in sepsis patients. The grantee, Beth Israel Deaconess Medical Center, will conduct an ancillary study using viscoelastic monitoring to examine the effects of randomly assigned fluid resuscitation strategies on coagulation parameters in sepsis patients. Specifically, the study aims to: 1) analyze how liberal versus restrictive fluid administration impacts coagulation measurements...

The Department of the Army Medical Command awarded a $10,265,040 project grant to Humanetics Corp to develop an injectable suspension of BIO 300 to treat radiation-induced lung injury. The grant period runs from July 1, 2022 to June 30, 2026. The funding supports the Military Medical Research and Development program (CFDA 12.420), which aims to transform military and public health care through innovative biomedical research solutions. Specifically, the award will allow Humanetics Corp to...

Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Boston Children's Hospital a $1.748 million Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to develop intravenous oxygen (IVO2) therapy for treating cardiac arrest. The grant, awarded May 21, 2025, with completion targeted for March 31, 2029, supports research on pH-responsive polymeric microbubbles (PMBs)—oxygen-carrying particles with polymer shells approximately...

The Department of the Army Medical Command awarded Northwestern University a $299,971 cooperative agreement from September 1, 2022 to August 31, 2024 to develop an Anesthesia Resuscitation Kit (ARK) for prolonged field care of military casualties with traumatic brain injury. The award is being made through the Military Medical Research and Development program (CFDA 12.420), which supports biomedical research that transforms healthcare for service members and the public through innovative...

Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a $761,262 Project Grant to The Trustees of Columbia University in the City of New York (Health Sciences Division) for research titled "Intravenously Injected Mesenchymal Stromal Cells Protect Against Acute Lung Injury by Transferring Mitochondria to Restore Endothelial Function." The award, effective September 1, 2025, through June 30, 2029, falls under the Cardiovascular Diseases Research...

This Project Grant award from the Department of the Army Medical Command provides $3,940,561 to fund the "Breathing Low Oxygen to Enhance Spinal Stimulation Training and Functional Recovery in Persons with Chronic Spinal Cord Injury: The BO2ST Trial" project under the Military Medical Research and Development program (CFDA 12.420). The award period is from September 30, 2022 through September 29, 2026. The project aims to investigate the extent to which daily acute intermittent hypoxia...

This $8,042,749 federal Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) is funding research at The Ohio State University to enhance the safety and efficacy of low-titer Group O whole blood. The research involves determining optimal concentrations of hemopexin, haptoglobin, and transferrin to neutralize hemolytic byproducts during ex vivo storage of whole blood units. The project includes testing this protein...

This $8.7 million project grant from the Department of the Army Medical Command, under the Military Medical Research and Development program (CFDA 12.420), supports the development of patient care technologies for permanent ambulatory artificial lung support from May 2022 to April 2026. Carnegie Mellon University is the primary awardee and will develop technologies to transition a pulmonary assist system to long-term support of chronic lung disease patients. Vanderbilt University Medical...

The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. was awarded a $277,569 cooperative agreement from the Department of Defense Uniformed Services University of the Health Sciences to develop and test acetazolamide as a treatment to extend the golden hour for trauma patients. Under the Uniformed Services University Medical Research Projects program (CFDA 12.750), the Foundation will conduct research from November 1, 2022 to April 30, 2025 to evaluate whether...

Federal Project Grant Award Summary Mainehealth received a $2.2 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective June 15, 2025, through June 14, 2028. The award funds research investigating the efficacy of tranexamic acid to reduce capillary leak, tissue edema, and fluid resuscitation requirements following severe burn injury. This research directly supports the DHA's mission to advance biomedical...