Our goal is to develop biomarkers of immunotherapy response using AI models from H & E-stained histology images
Ended Project Grant Awarded Last action
- Award ID
- W81XWH2210367
- Recipient
-
Vindhya Data Science Inc. UEI LENFU46TUBH8
- Awarding agency
-
Defense Health Agency
Department of Defense
- Obligated
- $0
Award facts
- Assistance listing
- 12.420 Military Medical Research and Development
- Completion date
- Originally
- Place of performance
- Morrisville, NC, USA
Award details come from USAspending.gov.
Description
We will first train our model to identify immune cell types on histology images, and then utilize the 2-D spatial patterns of these immune cells as features to predict response to immunotherapy. For the first part of our model, we will generate training labels for classifying the immune cells using multiplex immunofluorescence (MIF). For each cell type, we will develop a separate AI model to predict a probability map of the presence of that cell on the original histology image. These probability maps will serve as input feature sets for predicting response to immunotherapy. MIF data are only needed for training models to predict cell types and will not be needed when we test our model. Our two-staged model will then be applied to histological images with H & E stains to predict responders to immunotherapy.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Amendment | $0 | |
| Original award | $0 |
Quick answers
Who received award W81XWH2210367?
W81XWH2210367 was awarded to Vindhya Data Science Inc. by Defense Health Agency (Department of Defense) on September 30, 2022.
How much is award W81XWH2210367 worth?
$0 has been obligated on W81XWH2210367.
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