Project Grant W81XWH2210311

The National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), awarded a $459,097 Project Grant to Pison Technology, Inc., a minority-owned small business in Boston, Massachusetts. The grant, awarded on June 12, 2025, will fund the development of a digital biomarker for amyotrophic lateral sclerosis (ALS) using Pison's wrist-worn neural biosensor device. The goal is to leverage the...

The National Science Foundation awarded Cardiophi LLC $532,000 under the Technology, Innovation, and Partnerships program to develop an artificial intelligence solution for the automated interpretation of electrocardiograms. The project aims to refine existing deep learning-based algorithms for detecting irregular heartbeats, develop methods for predicting the onset of cardiac arrhythmias, and create interpretable and explainable tools to provide insights from ECG signals to clinicians....

This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $275,737 to Rewire Neuroscience LLC to develop and validate a machine learning platform for predicting the ototoxic potential of pharmaceutical compounds. The key objectives are to: 1) optimize and apply an innovative machine learning model that can categorize drugs as ototoxic or...

This $1,417,500 Project Grant awarded by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) funds the development of "Electrified Cryo-EM", a novel tool that can kinetically trap biological systems in their metastable, non-equilibrium states. The research aims to unravel the structural changes in neurons during an action potential across multiple length scales, from voltage-gated channel proteins to the synaptic junction. Specifically,...

This Project Grant award from the National Science Foundation (NSF) under the Engineering program (CFDA 47.041) provides $199,992 to Boston University to develop a high-throughput electrical stimulation screening platform for assessing the long-term effects of cardiac contractility modulation (CCM) devices on engineered human heart tissue. The project will support a postdoctoral scholar co-mentored by researchers at the Food and Drug Administration (FDA) and Boston University to advance...

The National Science Foundation awarded a $550,000 Project Grant to Northeastern University under the Technology, Innovation, and Partnerships federal grant program (CFDA 47.084) to develop a smart seizure prediction system using AI-enabled implantable sensor networks. The system will use embedded artificial intelligence algorithms to enable in-situ medical inference for patients with neurological disorders not treatable with antiepilepsy medications. Northeastern University will develop the...

This Project Grant award of $621,065 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will fund the development of advanced genetically encoded voltage indicators (GEVIs) optimized for two-photon microscopy. The goal is to create GEVIs with improved sensitivity for detecting subthreshold signals and enhanced response kinetics to reliably capture rapid action potentials...

This $325,672 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Advanced Brain Monitoring, Inc., a veteran-owned small business in Carlsbad, California. The grant funds the development and validation of a novel mobile electroencephalography (EEG) platform to provide accessible, cost-effective cognitive assessments for individuals suffering from neurological manifestations of...

This $275,000 project grant from the National Science Foundation's Engineering Directorate (CFDA 47.041) will fund the development of novel electronic-photonic silicon carbide neural probes for recording and stimulating neural activity. The Georgia Tech Research Corporation will receive funding on behalf of collaborating researchers to design penetrating neural probes made entirely of silicon carbide, a robust material proven to withstand the corrosive brain environment long-term. The probes...

This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is for the development and commercialization of an automated platform for high-throughput behavioral and electrophysiology research in freely behaving rats. The $1,266,318 award to Spikegadgets, Inc., a neuroscience research equipment company based in San Francisco, CA, will fund the creation of an integrated system that can administer operant...