This $427,625 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program will support research at the University of North Carolina at Chapel Hill to characterize the pulmonary immune response induced by single and multiple exposures to combustion products from military burn pits. The studies will use a controlled furnace to burn various components found in military burn pits, including plastics,...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $567,093.00 to The Regents of the University of California (UC Berkeley) to investigate the impact of wildfire exposure on human DNA methylation and health. The key objectives of this 2-year award, which runs from March 2025 to March 2027, are to: 1) develop comprehensive wildfire exposure assessments for a cohort of 5,000 adults in...
This R21 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $433,950 to the University of California, Davis to study the impact of wildfire smoke exposure on lung injury and disease in pediatric populations. The key objectives are to: 1) Define the contribution of age on the toxicity of wood smoke particles in respiratory and alveolar epithelium, 2) Investigate the effect of early life wood...
This $646,476 Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program will support research at the University of California, Los Angeles (UCLA) to investigate how environmental exposure to inorganic arsenic impacts epigenetic regulation and transgenerational inheritance. The overarching goal is to understand how arsenic triggers epigenetic changes that can resist developmental reprogramming in...
The Defense Health Agency awarded a $1,010,604 Project Grant to Lawrence Livermore National Security, LLC (LLNS) under the Military Medical Research and Development program (CFDA 12.420) to conduct research on the "Adverse Neural Effects of Inhalation Exposure to Burn Pits". The grant, which runs from August 1, 2025 to July 31, 2028, supports advanced biomedical research aimed at transforming healthcare for military service members, veterans, and the public. LLNS, which operates the...
This federal Project Grant award of $795,848 from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program will support research at the University of California, Davis (UC Davis) to examine the impacts of prenatal wildfire smoke exposure on maternal immune function, epigenetic changes in children, and subsequent child neurodevelopmental and behavioral outcomes. The research aims to elucidate the immunologic and epigenetic pathways...
The Department of Defense's Defense Health Agency has awarded a $2,650,080 Project Grant to National Jewish Health, a non-profit hospital and research center in Denver, Colorado. The grant, titled "ROLE OF BURN PIT-RELATED PARTICULATE MATTER IN DRIVING DEPLOYMENT-RELATED LUNG DISEASE," is funded through the Military Medical Research and Development program (CFDA 12.420). The project aims to investigate the impact of exposure to burn pit particulate matter on the development of lung...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $409,750 to the University of South Carolina to investigate the transformation of metal oxide nanomaterials in wildland-urban interface (WUI) fires and their potential impact on causing congenital heart disease. The key objectives are to: 1) Test the hypothesis that fire-transformed metal oxide nanomaterials result in higher cardiac...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, is supporting research to investigate the genetic mechanisms underlying maladaptive respiratory responses to air pollution, specifically ozone (O3) exposure. The $671,165 award, spanning January 1, 2025 to October 31, 2029, will enable researchers at the University of North Carolina at Chapel Hill to: Profile the transcriptomes and...
This $213,284 federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program will support research to investigate the role of extracellular vesicles (EVs) in mediating the health effects of wildfire smoke exposure, particularly in individuals with asthma. The key objectives are to examine whether EV release and content associated with the hypoxia-inducible factor 1 (HIF-1) pathway differentiate the...