Project Grant W81XWH1910743

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded $624,000 to the University of Colorado-Denver under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) on April 1, 2026, with a completion date of March 31, 2028. This R21 Trailblazer Award funds the development of a novel ex vivo organ treatment technology designed to improve heart transplant outcomes and expand the usable donor organ supply. The project...

Federal Project Grant Award Summary Perfusion Solutions Inc. received a $320,838 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 5, 2025, with completion targeted for February 28, 2027. The award supports Phase I development of a fail-safe, high-output cavopulmonary assist pump designed for pediatric and congenital heart disease patients with single ventricle physiology...

Summary of AI-LIVER Federal Project Grant Award The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded Icahn School of Medicine at Mount Sinai a $3.39 million Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) for the three-year period from September 1, 2025, through August 31, 2028. The AI-LIVER project delivers two primary products: (1) establishment of an international cohort of...

This National Heart, Lung, and Blood Institute (NHLBI) Project Grant, awarded under the Cardiovascular Diseases Research program (CFDA 93.837), supports research at Florida International University to develop methods for extended ex vivo storage, preservation, and rehabilitation of living heart valve allografts for pediatric transplantation. The $1.42 million award, effective September 1, 2025 through May 31, 2030, addresses a critical clinical need for pediatric patients with congenital valve...

This federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $199,867 to the University of Washington to develop an innovative approach for long-term cryopreservation of organs using ice-free vitrification and single-mode electromagnetic resonance (SMER) heating. The project aims to overcome barriers in organ cryopreservation by advancing vitrification and EM heating technologies to enable fast and uniform rewarming of cryopreserved...

Federal Project Grant Award Summary Oregon State University received a $560,293 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286), awarded June 1, 2026, with completion expected by May 31, 2029. The project aims to develop advanced cryopreservation methods that extend organ viability from hours to years through high-throughput...

Federal Project Grant Award Summary Mayo Clinic received a $739,562 project grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded August 15, 2025, with performance extending through May 31, 2029. The grant supports research investigating the epigenetic regulation of donor heart preservation mediated by BRD4 (bromodomain and extraterminal domain protein 4), a protein that plays a critical role in cardiac function...

Federal Project Grant Award Summary New York University School of Medicine received a $165,672 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) effective September 15, 2025, with completion targeted for August 31, 2030. The award funds research aimed at increasing heart donor utilization in the United States by addressing critical barriers to heart transplant (HT) availability. The research will...

Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Ohio State University a Project Grant of $1,574,578 under the Cardiovascular Diseases Research program (CFDA 93.837) effective July 1, 2026, with completion scheduled for December 31, 2027. The award funds research into novel targeted modified messenger ribonucleic acid (mRNA) delivery strategies to improve outcomes in donation after circulatory death (DCD) heart transplantation. Specifically, the research...

Federal Project Grant Award Summary Massachusetts General Hospital's Research Management Division received a $159,104 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective February 13, 2026 through August 31, 2027. The award funds development and validation of Veloporation for Cryoprotective Agent Loading (VelCPA), a novel...