Project Grant W81XWH1710649

The federal Project Grant award for "NEUROPHYSIOLOGY OF POST-TRAUMATIC EPILEPSY: UNRAVELING EPILEPTOGENESIS SIGNALS BIOMARKERS", totaling $860,998.00, was provided by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) federal grant program. This award supports advanced biomedical research initiatives focused on transforming healthcare for military service members and the broader public, with a particular emphasis on conditions relevant to the...

The Department of the Army Medical Command awarded a $3,099,990 project grant to the Western Institute For Veterans Research under the Military Medical Research and Development program (CFDA 12.420). The grant will fund the MILITARY INJURIES - UNDERSTANDING POST-TRAUMATIC EPILEPSY (MINUTE): BIOINFORMATICS WITH BIG DATA TO EXAMINE MULTIMODAL PTE BIOMARKERS project from September 30, 2021 through September 29, 2025. The project aims to utilize bioinformatics and big data approaches to examine...

The Department of Defense's (DoD) Military Medical Research and Development program (CFDA 12.420) awarded a $1,009,369 project grant to Brigham & Women's Hospital in Boston, MA. The grant funds a 3-year research project titled "Probing the Role of Ion Channels as Mediators of Post-Traumatic Epileptogenesis: GIRK Channel Modulation as a Roadmap to Therapy." The research aims to: 1) characterize aberrant neuronal activity patterns in the brain following traumatic brain injury...

This federal Project Grant award from the Department of the Army Medical Command, under the Military Medical Research and Development program (CFDA 12.420), provides $665,655.00 to The University of Kentucky Research Foundation to conduct research on "LEVERAGING PRECLINICAL REPEATED BLAST TRAUMATIC BRAIN INJURY TO MODEL MILITARY-RELEVANT POST-TRAUMATIC EPILEPSY". The project aims to advance the understanding and treatment of post-traumatic epilepsy, a condition of particular...

This Project Grant from the Defense Health Agency provides $745,381 to Virginia Commonwealth University from June 1, 2023 through May 31, 2026 to support research on "POST-TRAUMATIC EPILEPTOGENESIS: ROLE OF NEOCORTICAL-HIPPOCAMPAL INTERACTIONS" under the Military Medical Research and Development program (CFDA 12.420). VCU will conduct this research to advance the program's goals of transforming military and public healthcare through innovative biomedical research solutions. Subawards...

The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $444,125 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to the University of Virginia (UVA) to conduct research on the relationship between penetrating brain injury, toxic metal exposure, and the development of post-traumatic epilepsy. The study aims to determine whether the duration of exposure to retained metal fragments, such as copper and lead, in...

The Department of the Army Medical Command awarded $745,304 to Texas A&M University Health Science Center under the Military Medical Research and Development program (CFDA 12.420) to support the project "Epigenetic Therapy for Post-Traumatic Epilepsy" from September 30, 2022 through September 29, 2025. The project aims to develop innovative medical solutions for traumatic brain injury through basic, applied, and advanced biomedical research investigating epigenetic approaches to...

This Project Grant award of $424,175 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) aims to leverage existing large-scale whole exome sequencing (WES) and whole genome sequencing (WGS) datasets and biorepositories to identify additional genetic signals associated with post-traumatic stress disorder (PTSD). The research conducted at Virginia Commonwealth University will integrate rare genetic variants from WES/WGS data with...

The Defense Health Agency awarded Oklahoma State University a $371,617 Block Grant under the Military Medical Research and Development program (CFDA 12.420) to conduct research related to epilepsy. The award will support a 3-year project focused on two key objectives: Improving prediction of post-traumatic epilepsy (PTE) by enhancing machine learning models using electronic health record data from the VA and other sources. This will involve data preprocessing, model training, and the use of...

This Project Grant award R01MH139648 from the National Institute of Mental Health (NIMH) will fund research to study the structural and functional connectivity of the cerebellum and its relationship to posttraumatic stress disorder (PTSD). The $610,152 grant, awarded to Duke University, aims to analyze existing neuroimaging and clinical data from over 1,887 PTSD and trauma-exposed samples across 25 international cohorts. The research will investigate the influence of PTSD and trauma exposure...